[Hub]/) : Traits : Medication: Simvastatin :

chr15:90,730,363-92,135,418

Best TWAS P=3.45e-08 · Best GWAS P=7.24e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial FES 0.16 0.04 lasso 5 0.05 4.8e-05 4.2 -5.3 9.5e-08 -0.86 0.01 0.98 FALSE
2 GTEx Cells Transformed fibroblasts FES 0.28 0.17 enet 21 0.20 2.8e-15 5.0 -5.2 1.6e-07 -0.90 0.01 0.98 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma FES 0.06 0.05 blup 46 0.07 7.4e-14 5.0 -5.5 3.6e-08 -0.88 0.00 0.99 FALSE
4 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FES 0.08 0.07 enet 7 0.08 4.2e-09 5.0 -5.2 1.8e-07 -0.92 0.00 1.00 FALSE
5 The Cancer Genome Atlas Prostate Adenocarcinoma FES 0.12 0.09 lasso 5 0.08 4.1e-09 5.0 -5.3 1.2e-07 -0.91 0.01 0.99 FALSE
6 The Cancer Genome Atlas Testicular Germ Cell Tumors FES 0.32 0.26 lasso 2 0.25 2.0e-09 5.4 -5.4 5.9e-08 -1.00 0.00 1.00 FALSE
7 The Cancer Genome Atlas Thyroid Carcinoma FES 0.30 0.30 lasso 7 0.32 1.3e-31 5.4 -5.5 3.4e-08 -0.97 0.00 1.00 TRUE