Best TWAS P=3.45e-08 · Best GWAS P=7.24e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | FES | 0.16 | 0.04 | lasso | 5 | 0.05 | 4.8e-05 | 4.2 | -5.3 | 9.5e-08 | -0.86 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Cells Transformed fibroblasts | FES | 0.28 | 0.17 | enet | 21 | 0.20 | 2.8e-15 | 5.0 | -5.2 | 1.6e-07 | -0.90 | 0.01 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FES | 0.06 | 0.05 | blup | 46 | 0.07 | 7.4e-14 | 5.0 | -5.5 | 3.6e-08 | -0.88 | 0.00 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | FES | 0.08 | 0.07 | enet | 7 | 0.08 | 4.2e-09 | 5.0 | -5.2 | 1.8e-07 | -0.92 | 0.00 | 1.00 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FES | 0.12 | 0.09 | lasso | 5 | 0.08 | 4.1e-09 | 5.0 | -5.3 | 1.2e-07 | -0.91 | 0.01 | 0.99 | FALSE |
| 6 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | FES | 0.32 | 0.26 | lasso | 2 | 0.25 | 2.0e-09 | 5.4 | -5.4 | 5.9e-08 | -1.00 | 0.00 | 1.00 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | FES | 0.30 | 0.30 | lasso | 7 | 0.32 | 1.3e-31 | 5.4 | -5.5 | 3.4e-08 | -0.97 | 0.00 | 1.00 | TRUE |