TWAS
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Traits
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Traits
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Medication: Simvastatin
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chr2:20,529,948-21,958,745
Best TWAS P=8.57e-25 · Best GWAS P=2.03e-25 conditioned to 1
20.6M
20.8M
21M
21.2M
21.4M
21.6M
21.8M
22M
0
5
10
15
20
25
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
APOB
0.13
0.12
lasso
2
0.12
1e-14
10
-10
8.6e-25
-1
0
1
TRUE