TWAS hub - APOB

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.133	0.035	5.4e-08	0.123	0.072	0.107	0.11	0.123	8.4e-15	4.6e-09	5.2e-13	2.8e-13	1e-14

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1
LDL Cholesterol	325.6	515.3	515.3	-22.7
High cholesterol (Self-reported)	188.8	334.9	334.9	-18.3
Medication: Cholesterol lowering	79.3	123.2	123.2	-11.1
Cholesterol lowering medication	73.5	108.2	108.2	-10.4
Medication: Simvastatin	72.2	106.1	106.1	-10.3
Medication: Atorvastatin	38.7	47.8	47.8	-6.9
Triglycerides	22.8	37.3	37.3	-6.1
Cardiovascular Disease	20.9	69.1	69.1	-8.3
Medication for cholesterol, blood pressure or diabetes	20.7	34.3	34.3	5.9
Back pain experienced in last month	11.1	16.2	16.2	4.0
HDL Cholesterol	10.0	16.7	16.7	4.1
Alcohol drinker status: Previous	9.7	11.0	11.0	3.3
Medication: Aspirin	8.6	11.4	11.4	-3.4
Pain experienced in last month	6.9	11.5	11.5	-3.4
Heart attack/myocardial infarction (self-reported)	6.9	8.9	8.9	-3.0
Medication for cholesterol	6.7	10.1	10.1	3.2
Heart attack	6.3	8.1	8.1	-2.8
Angina (self-reported)	6.2	8.2	8.2	-2.9
Medication: Omeprazole (e.g. Zanprol)	5.7	6.9	6.9	2.6
Nervous feelings	5.4	10.1	10.1	3.2
Noisy workplace	5.3	6.6	6.6	-2.6
Medication: Aspirin	5.3	6.9	6.9	-2.6
Deep venous thrombosis (DVT) (self-reported)	5.0	6.5	6.5	2.5
Angina	4.9	6.4	6.4	-2.5
Medication: Gliclazide	4.7	5.3	5.3	2.3
Worry (Nagel 2018)	4.5	9.4	9.4	3.1
Blood clot in the leg (DVT)	4.5	5.8	5.8	2.4
Medication: Paracetamol	4.4	6.9	6.9	2.6
Pulse rate, automated reading	4.3	13.9	13.9	3.7
Illnesses of father: Heart disease	4.2	5.8	5.8	-2.4
Suffer from ‘nerves’	4.1	6.5	6.5	2.5
Coronary Artery Disease (CAD)	4.0	4.7	4.7	-2.2
Medication: Lansoprazole	4.0	4.6	4.6	2.1
Frequency of tenseness / restlessness in last 2 weeks	3.5	5.5	5.5	2.3
Bipolar Disorder (2018)	3.4	5.4	5.4	-2.3
Long-standing illness, disability or infirmity	3.3	5.0	5.0	2.2
Type 2 Diabetes (T2D) (2018)	3.1	5.8	5.8	2.4
Age at First Birth	2.9	4.3	4.3	2.1
Medication: Omeprazole	2.9	3.4	3.4	1.9
Medication: Paracetamol	2.7	4.5	4.5	2.1
Neck or shoulder pain in last month	2.7	3.8	3.8	2.0
Number of self-reported non-cancer illnesses	2.7	4.7	4.7	-2.2
Pain type(s) experienced in last month: Hip pain	2.7	3.4	3.4	1.9
Unable to work because of sickness or disability	2.7	3.5	3.5	1.9
Verbal and Numeric Reasoning (VNR)	2.6	6.3	6.3	2.5
Fasting Glucose	2.6	3.1	3.1	1.8
Bipolar Disorder or Schizophrenia	2.5	6.2	6.2	-2.5
Loud music exposure frequency	2.4	2.6	2.6	-1.6
Medication: Ibuprofen	2.4	2.9	2.9	1.7
Ever smoked	2.3	4.0	4.0	2.0
Neuroticism	2.2	5.3	5.3	2.3
Chronic bronchitis/emphysema (mother)	2.2	2.6	2.6	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.2	2.6	2.6	1.6
Neuroticism (Nagel 2018)	2.1	4.8	4.8	2.2
Sensitivity / hurt feelings	2.1	3.6	3.6	1.9
Had menopause	2.1	2.6	2.6	1.6
Diabetes (self-reported)	2.0	3.0	3.0	1.7
Tense / ‘highly strung’	1.9	3.2	3.2	1.8
Loneliness, isolation	1.9	2.7	2.7	1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.9	2.2	2.2	1.5
Eye problems/disorders: Diabetes related eye disease	1.8	1.9	1.9	1.4
Diabetes (mother)	1.8	2.3	2.3	1.5
Past tobacco smoking	1.8	3.3	3.3	-1.8
Hearing difficulty/problems with background noise	1.8	2.8	2.8	1.7
Prostate Cancer	1.7	2.3	2.3	1.5
Medication: Atenolol	1.7	2.2	2.2	-1.5
Neuroticism score	1.7	3.5	3.5	1.9
Hypothyroidism/myxoedema (self-reported)	1.7	3.2	3.2	-1.8
Medication: Metformin	1.6	2.3	2.3	1.5
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.1	2.1	1.5
Medication: Levothyroxine sodium	1.6	2.7	2.7	-1.6
Qualifications: nursing, teaching	1.6	2.5	2.5	1.6
Heel T-Score	1.5	12.3	12.3	3.5
Length of working week for main job	1.5	1.6	1.6	1.3
Comparative body size at age 10	1.5	4.2	4.2	2.0
Diabetes diagnosed by doctor	1.5	2.4	2.4	1.5
Intelligence (Savage-Jansen 2018)	1.4	4.3	4.3	2.1
Major Depression (MDD)	1.4	1.7	1.7	1.3
Waist circumference	1.4	5.1	5.1	2.3
Time employed in main current job	1.4	1.6	1.6	1.2
Migraine (self-reported)	1.4	1.7	1.7	1.3
Mouth/teeth dental problems: Mouth ulcers	1.4	2.2	2.2	1.5
Diastolic blood pressure, automated reading	1.4	4.5	4.5	2.1
Bipolar Disorder (2011)	1.3	1.2	1.2	-1.1
Leg pain on walking	1.3	1.6	1.6	1.3
Commuting to job workplace: Car/motor vehicle	1.3	1.5	1.5	1.2
Depressed Affect (Nagel 2018)	1.2	2.6	2.6	1.6
Respiratory disease	1.2	2.6	2.6	1.6
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	1.6	-1.3
Depression (self-reported)	1.2	1.4	1.4	1.2
Number of treatments/medications taken	1.1	1.9	1.9	-1.4
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	1.4	1.2
Headache pain in last month	1.1	1.8	1.8	1.4
Overall health rating	1.1	2.3	2.3	1.5
Depression (Nagel 2018)	1.0	1.5	1.5	1.2
Multivitamins +/- minerals	1.0	1.3	1.3	1.1
Had other major operations	1.0	1.2	1.2	1.1
Financial difficulties in last 2 years	1.0	1.3	1.3	-1.2
Age at first live birth	1.0	1.7	1.7	-1.3
Illnesses of siblings: Diabetes	1.0	1.2	1.2	1.1
Rheumatoid Arthritis	0.9	1.2	1.2	-1.1
Smoking Status	0.9	2.2	2.2	1.5
Fluid intelligence score	0.9	1.9	1.9	1.4
Lung cancer (father)	0.9	1.0	1.0	1.0
Exposure to tobacco smoke at home	0.9	1.0	1.0	1.0
Age at last live birth	0.9	1.3	1.3	-1.1
Schizophrenia (2018)	0.8	1.7	1.7	-1.3
HbA1C	0.8	0.9	0.9	0.9
Vitamin and mineral supplements	0.8	1.0	1.0	-1.0
Hip circumference	0.8	3.2	3.2	1.8
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	1.3	1.1
Medication: Ventolin 100micrograms inhaler	0.8	1.0	1.0	1.0
Number of children fathered	0.8	0.9	0.9	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	0.9	1.0
Number of full sisters	0.8	1.0	1.0	1.0
Friendships satisfaction	0.8	1.0	1.0	1.0
Breast Cancer	0.7	1.6	1.6	1.3
Mean Putamen Volume	0.7	0.8	0.8	0.9
Type 2 Diabetes (T2D) (2012)	0.7	0.9	0.9	-0.9
Age when periods started (menarche)	0.7	1.6	1.6	-1.3
Hayfever, allergic rhinitis or eczema	0.7	1.5	1.5	-1.2
Osteoporosis (self-reported)	0.7	0.8	0.8	0.9
Miserableness	0.7	1.3	1.3	1.1
Body Mass Index (BMI) (2010)	0.6	0.9	0.9	-0.9
Primary Biliary Cirrhosis	0.6	0.8	0.8	0.9
Waist Hip Ratio (WHR)	0.6	2.5	2.5	1.6
Pack years adult smoking proportion	0.6	1.0	1.0	-1.0
Relative age voice broke	0.6	1.0	1.0	1.0
Mouth/teeth dental problems: Dentures	0.6	1.1	1.1	1.0
Breastfed as a baby	0.6	0.7	0.7	-0.8
High blood pressure (siblings)	0.6	0.8	0.8	-0.9
Number of operations (self-reported)	0.6	0.9	0.9	0.9
Basal cell carcinoma (self-reported)	0.6	0.7	0.7	-0.8
Lupus	0.5	0.8	0.8	0.9
BMI	0.5	3.1	3.1	1.8
Hypothyroidism (self reported)	0.5	1.2	1.2	-1.1
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	0.5	-0.7
Number of incorrect matches in round	0.5	0.8	0.8	-0.9
Alcohol usually taken with meals	0.5	0.7	0.7	-0.9
Hair/balding pattern: Pattern 2	0.5	0.6	0.6	0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.0	1.0	1.0
Mouth/teeth dental problems	0.5	0.7	0.7	-0.9
Trunk predicted mass	0.5	2.6	2.6	1.6
Birth weight	0.5	1.0	1.0	-1.0
Shortness of breath walking on level ground	0.5	0.6	0.6	-0.8
Medication for pain relief, constipation, heartburn	0.5	0.8	0.8	-0.9
Alcohol intake frequency.	0.5	1.3	1.3	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	0.6	-0.8
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	0.6	0.8
Knee pain experienced in last month	0.5	0.8	0.8	0.9
Tinnitus: Yes, now most or all of the time	0.5	0.6	0.6	-0.8
Medication: Lisinopril	0.5	0.7	0.7	-0.8
Age started oral contraceptive pill	0.5	0.6	0.6	0.8
Pack years of smoking	0.5	0.7	0.7	-0.9
Neuroticism (2016)	0.4	0.5	0.5	0.7
Lung FEV1/FVC ratio	0.4	1.9	1.9	1.4
Frequency of depressed mood in last 2 weeks	0.4	0.6	0.6	0.8
Ever used hormone-replacement therapy (HRT)	0.4	0.5	0.5	0.7
Medication for hormone replacement therapy	0.4	0.4	0.4	-0.6
Medication: Co-codamol	0.4	0.5	0.5	-0.7
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	0.4	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	1.0	1.0
Stomach or abdominal pain in last month	0.4	0.5	0.5	0.7
Supplements: Glucosamine	0.4	0.6	0.6	0.8
Body mass index (BMI)	0.4	1.5	1.5	1.2
Weight	0.4	2.1	2.1	1.4
Trunk fat-free mass	0.4	2.3	2.3	1.5
Pulse rate	0.4	0.6	0.6	0.8
Mouth/teeth dental problems: Bleeding gums	0.4	0.6	0.6	0.8
Leg fat percentage (right)	0.4	1.4	1.4	1.2
Exposure to tobacco smoke outside home	0.4	0.5	0.5	0.7
Health satisfaction	0.4	0.5	0.5	0.7
Had major operations	0.4	0.4	0.4	0.7
Smoking status: Previous	0.4	0.5	0.5	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	0.9	0.9
Average weekly red wine intake	0.4	0.5	0.5	-0.7
Commuting to job workplace: Public transport	0.4	0.5	0.5	-0.7
Arm fat-free mass (left)	0.4	2.1	2.1	1.5
Alzheimer’s Disease (in father)	0.3	0.4	0.4	0.6
Crohns Disease (2017)	0.3	0.7	0.7	-0.8
Blood White Count	0.3	2.0	2.0	1.4
Systolic Blood Pressure	0.3	1.4	1.4	-1.2
Lung FVC	0.3	1.4	1.4	-1.2
Hand grip strength (left)	0.3	0.7	0.7	0.9
Ever had hysterectomy (womb removed)	0.3	0.4	0.4	-0.6
Supplements: Zinc	0.3	0.3	0.3	0.6
Average weekly fortified wine intake	0.3	0.3	0.3	-0.6
Qualifications: CSEs or equivalent	0.3	0.4	0.4	-0.6
Arm fat-free mass (right)	0.3	1.5	1.5	1.2
Heart disease (mother)	0.3	0.3	0.3	-0.6
Whole body fat mass	0.3	1.1	1.1	1.1
Leg fat mass (right)	0.3	1.3	1.3	1.1
Arm predicted mass (right)	0.3	1.7	1.7	1.3
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.3	0.6
Medication: Bendroflumethiazide	0.3	0.5	0.5	0.7
Leg fat percentage (left)	0.3	1.1	1.1	1.0
Myopia	0.3	0.4	0.4	-0.6
Leg fat mass (left)	0.3	1.2	1.2	1.1
Arm predicted mass (left)	0.3	1.6	1.6	1.3
Schizophrenia (2014)	0.2	0.5	0.5	-0.7
Blood Red Count	0.2	2.3	2.3	1.5
Fed-up feelings	0.2	0.4	0.4	0.6
High blood pressure	0.2	0.7	0.7	0.8
Trunk fat mass	0.2	1.0	1.0	1.0
Medication: Ramipril	0.2	0.3	0.3	-0.5
Happiness	0.2	0.2	0.2	0.5
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.2	-0.4
Impedance of arm (left)	0.2	0.8	0.8	-0.9
Arm fat mass (right)	0.2	1.0	1.0	1.0
Birth weight of first child	0.2	0.3	0.3	0.6
Body fat percentage	0.2	0.7	0.7	0.8
Mean time to correctly identify matches	0.2	0.4	0.4	0.6
Comparative height size at age 10	0.2	1.4	1.4	1.2
Supplements: Vitamin C	0.2	0.2	0.2	0.5
Whole body fat-free mass	0.2	1.2	1.2	1.1
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.3	-0.5
Osteoarthritis (self-reported)	0.2	0.2	0.2	0.5
Smoking status: Current	0.2	0.4	0.4	0.6
Whole body water mass	0.2	1.1	1.1	1.1
Arm fat mass (left)	0.2	0.8	0.8	0.9
Wears glasses or contact lenses	0.2	0.2	0.2	0.5
Ever taken oral contraceptive pill	0.2	0.2	0.2	-0.5
Alcohol drinker status: Never	0.2	0.2	0.2	-0.5
Basal metabolic rate	0.2	1.0	1.0	1.0
Supplements: Calcium	0.2	0.2	0.2	0.5
Schizophrenia vs Biploar Disorder	0.1	0.1	0.1	0.3
Irritable Bowel Disease (IBD)	0.1	0.2	0.2	-0.4
Ovarian Cancer	0.1	0.1	0.1	0.4
Crohns Disease (2012)	0.1	0.1	0.1	-0.3
Ulcerative Colitis	0.1	0.2	0.2	0.4
Blood Platelet Count	0.1	0.9	0.9	0.9
Average weekly spirits intake	0.1	0.2	0.2	0.4
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.2	0.4
Severe depression (siblings)	0.1	0.1	0.1	0.3
Impedance of leg (right)	0.1	0.3	0.3	0.6
Leg fat-free mass (left)	0.1	0.3	0.3	0.5
Trunk fat percentage	0.1	0.6	0.6	0.8
Current tobacco smoking	0.1	0.1	0.1	0.3
High blood pressure (mother)	0.1	0.1	0.1	0.4
Forced vital capacity (FVC)	0.1	0.5	0.5	-0.7
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.2	-0.4
Allergy	0.1	0.3	0.3	-0.6
Arm fat percentage (right)	0.1	0.4	0.4	0.7
Alcohol intake versus 10 years previously	0.1	0.1	0.1	0.3
Falls in the last year	0.1	0.1	0.1	-0.4
Illnesses of mother	0.1	0.1	0.1	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	0.2	0.5
Hair/balding pattern: Pattern 4	0.1	0.3	0.3	0.5
Peak expiratory flow (PEF)	0.1	0.3	0.3	0.6
Forced vital capacity (FVC), Best measure	0.1	0.4	0.4	-0.6
Number of full brothers	0.1	0.2	0.2	-0.4
Wheeze or whistling in the chest in last year	0.1	0.1	0.1	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.1	-0.3
Qualifications: College or University degree	0.1	0.2	0.2	-0.5
Mouth/teeth dental problems: Loose teeth	0.1	0.2	0.2	-0.4
Family relationship satisfaction	0.1	0.1	0.1	0.3
Hypertension (Self-reported)	0.1	0.3	0.3	0.5
Arm fat percentage (left)	0.1	0.2	0.2	0.5
Mood swings	0.1	0.1	0.1	0.3
Ever had bowel cancer screening	0.1	0.1	0.1	0.2
Commuting to job workplace: Walk	0.1	0.1	0.1	0.4
Eye problems/disorders: Cataract	0.1	0.1	0.1	-0.3
Breast cancer (self-reported)	0.1	0.1	0.1	-0.3
Illnesses of father: High blood pressure	0.1	0.2	0.2	-0.4
Average weekly beer plus cider intake	0.1	0.1	0.1	0.4
Irritability	0.1	0.2	0.2	-0.4
Fractured/broken bones in last 5 years	0.1	0.1	0.1	-0.3
Ever depressed for a whole week	0.1	0.2	0.2	-0.4
Commuting to job workplace: Cycle	0.1	0.1	0.1	-0.3
Impedance of whole body	0.1	0.3	0.3	-0.6
Alzheimer’s Disease (in mother)	0.0	0.0	0.0	-0.2
Alzheimer’s Disease (including proxy)	0.0	0.0	0.0	0.0
Ulcerative Colitis (UC)	0.0	0.0	0.0	-0.1
Reaction Time	0.0	0.0	0.0	0.2
Blood Eosinophil Count	0.0	0.4	0.4	0.6
Height	0.0	0.0	0.0	0.1
Allergy or Eczema	0.0	0.0	0.0	-0.2
Chronotype (morning person)	0.0	0.0	0.0	-0.1
Hair Pigment	0.0	1.3	1.3	-1.1
Tanning	0.0	0.0	0.0	0.1
Hearing difficulty/problems: Yes	0.0	0.0	0.0	0.1
Relative age of first facial hair	0.0	0.1	0.1	-0.3
Systolic blood pressure, automated reading	0.0	0.1	0.1	-0.3
Diabetes (father)	0.0	0.0	0.0	0.1
Hand grip strength (right)	0.0	0.1	0.1	0.3
Townsend deprivation index at recruitment	0.0	0.0	0.0	0.2
Maternal smoking around birth	0.0	0.0	0.0	0.2
Taking other prescription medications	0.0	0.0	0.0	-0.0
Serious illness, injury or assault to yourself	0.0	0.0	0.0	0.0
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.0	0.2
Sitting height	0.0	0.1	0.1	-0.3
Chronic bronchitis/emphysema (father)	0.0	0.0	0.0	-0.1
Impedance of leg (left)	0.0	0.1	0.1	0.2
Leg predicted mass (left)	0.0	0.2	0.2	0.5
Qualifications: None of the above	0.0	0.1	0.1	0.3
Pain all over the body in last month	0.0	0.0	0.0	0.0
Illnesses of siblings	0.0	0.0	0.0	0.2
Impedance of arm (right)	0.0	0.2	0.2	-0.5
Father’s age at death	0.0	0.1	0.1	-0.2
Worrier / anxious feelings	0.0	0.0	0.0	0.2
Hair/balding pattern: Pattern 3	0.0	0.0	0.0	-0.0
Number of live births	0.0	0.0	0.0	0.2
Forced expiratory volume in 1-second (FEV1)	0.0	0.0	0.0	-0.1
Qualifications: A levels/AS levels or equivalent	0.0	0.0	0.0	-0.0
Asthma	0.0	0.0	0.0	0.2
Prospective memory result	0.0	0.0	0.0	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.0	0.0	0.0	-0.2
Pulse wave Arterial Stiffness index	0.0	0.0	0.0	-0.1
Standing height	0.0	0.3	0.3	0.6
Pulse wave reflection index	0.0	0.0	0.0	-0.1
Ever highly irritable/argumentative for 2 days	0.0	0.0	0.0	-0.1
Qualifications: O levels/GCSEs or equivalent	0.0	0.1	0.1	0.3
Glaucoma (self-reported)	0.0	0.0	0.0	-0.2
Gout (self-reported)	0.0	0.0	0.0	-0.1
Medication: Amlodipine	0.0	0.0	0.0	-0.0
Worry too long after embarrassment	0.0	0.0	0.0	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.0	0.0	-0.2
Pulse wave peak to peak time	0.0	0.0	0.0	0.2
Eye problems/disorders: None of the above	0.0	0.0	0.0	0.1
Emphysema/chronic bronchitis	0.0	0.0	0.0	0.2
Medication: Blood pressure	0.0	0.0	0.0	-0.2
Medication: Allopurinol	0.0	0.0	0.0	-0.0
Medication: Seretide 50 evohaler	0.0	0.0	0.0	-0.1
Chest pain or discomfort	0.0	0.0	0.0	-0.2
Leg fat-free mass (right)	0.0	0.1	0.1	0.3
Mineral and other dietary supplements	0.0	0.1	0.1	-0.3
Asthma (self-reported)	0.0	0.0	0.0	0.2
Illnesses of father: None of the above (group 1)	0.0	0.0	0.0	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.0	0.0	-0.0
Leg predicted mass (right)	0.0	0.1	0.1	0.2
Average weekly champagne plus white wine intake	0.0	0.0	0.0	0.1
Guilty feelings	0.0	0.0	0.0	-0.1
Hearing aid user	0.0	0.0	0.0	-0.0
Mother’s age at death	0.0	0.0	0.0	0.1
Financial situation satisfaction	0.0	0.0	0.0	0.1
Eye problems/disorders: Glaucoma	0.0	0.0	0.0	-0.1
Medication: Blood pressure	0.0	0.0	0.0	0.2
Supplements: Fish oil (including cod liver oil)	0.0	0.0	0.0	-0.2
Risk taking	0.0	0.0	0.0	-0.1
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.0	0.1
Vascular/heart problems diagnosed by doctor	0.0	0.0	0.0	0.2
Heart disease (siblings)	0.0	0.1	0.1	-0.2

Hub : Genes

APOB

Models

Trait associations