Best TWAS P=1.72e-09 · Best GWAS P=2.4e-29 conditioned to 9.81e-18
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | EPOR | 0.11 | 0.04 | lasso | 7 | 0.04 | 3.8e-04 | -6.3 | -6.0 | 2.2e-09 | 0.48 | 0.52 | 0.38 | TRUE |
| 2 | NTR | Blood | SMARCA4 | 0.07 | 0.06 | lasso | 11 | 0.06 | 9.0e-18 | -5.6 | 5.3 | 1.2e-07 | -0.38 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | KANK2 | 0.28 | 0.26 | lasso | 3 | 0.26 | 4.6e-29 | 5.9 | 5.9 | 2.9e-09 | -0.02 | 0.00 | 1.00 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SPC24 | 0.06 | 0.00 | enet | 15 | 0.01 | 1.4e-02 | -9.4 | 6.0 | 1.7e-09 | -0.35 | 0.00 | 0.55 | TRUE |