Best TWAS P=4.68e-12 · Best GWAS P=1.67e-13 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | RASGRP1 | 0.31 | 0.34 | lasso | 5 | 0.33 | 6.6e-23 | 6.2 | 6.2 | 4.3e-10 | 0.77 | 0.87 | 0.13 | FALSE |
| 2 | GTEx | Skin Not Sun Exposed Suprapubic | RASGRP1 | 0.37 | 0.44 | lasso | 5 | 0.42 | 3.6e-25 | 6.2 | 6.3 | 3.4e-10 | 0.77 | 0.87 | 0.13 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RASGRP1 | 0.37 | 0.33 | lasso | 6 | 0.38 | 1.2e-32 | 6.1 | 6.0 | 2.3e-09 | 0.76 | 0.88 | 0.12 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | RASGRP1 | 0.10 | 0.01 | blup | 67 | 0.02 | 1.9e-02 | 3.4 | 5.2 | 2.4e-07 | 0.67 | 0.03 | 0.31 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | RASGRP1 | 0.05 | 0.03 | lasso | 2 | 0.02 | 1.9e-03 | 7.4 | 6.9 | 4.7e-12 | 0.97 | 0.01 | 0.97 | TRUE |