[Hub]/) : Traits : Medication: Levothyroxine sodium : ← →

chr15:38,088,200-39,556,796

Best TWAS P=4.68e-12 · Best GWAS P=1.67e-13 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	The Cancer Genome Atlas	Prostate Adenocarcinoma	RASGRP1	0.05	0.03	lasso	2	0.02	1.9e-03	7.4	6.9	4.7e-12	0.97	0.01	0.97	TRUE
2	GTEx	Skin Not Sun Exposed Suprapubic	RASGRP1	0.37	0.44	lasso	5	0.42	3.6e-25	6.2	6.3	3.4e-10	0.77	0.87	0.13	FALSE
1	GTEx	Esophagus Mucosa	RASGRP1	0.31	0.34	lasso	5	0.33	6.6e-23	6.2	6.2	4.3e-10	0.77	0.87	0.13	FALSE
3	GTEx	Skin Sun Exposed Lower leg	RASGRP1	0.37	0.33	lasso	6	0.38	1.2e-32	6.1	6.0	2.3e-09	0.76	0.88	0.12	FALSE
4	The Cancer Genome Atlas	Colon Adenocarcinoma	RASGRP1	0.10	0.01	blup	67	0.02	1.9e-02	3.4	5.2	2.4e-07	0.67	0.03	0.31	FALSE