[Hub]/) : Traits : Medication: Levothyroxine sodium : ← →

chr17:39,589,083-41,265,776

Best TWAS P=1.55e-11 · Best GWAS P=1.4e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PTRF 0.05 0.00 bslmm 264 0.01 6.3e-03 2.6 -5.4 7.0e-08 -0.43 0.06 0.16 FALSE
2 CommonMind Brain Pre-frontal Cortex RAB5C 0.21 0.18 bslmm 326 0.18 8.1e-21 6.7 6.4 2.0e-10 0.96 0.00 1.00 FALSE
3 GTEx Adipose Visceral Omentum RAB5C 0.19 0.02 lasso 6 0.02 3.7e-02 4.5 5.6 2.8e-08 0.94 0.01 0.92 FALSE
4 GTEx Esophagus Muscularis RAB5C 0.20 0.12 lasso 6 0.11 3.1e-07 4.5 5.4 5.6e-08 0.91 0.01 0.99 FALSE
5 GTEx Muscle Skeletal RAB5C 0.10 0.07 lasso 2 0.06 3.9e-06 6.7 6.7 1.9e-11 1.00 0.00 1.00 FALSE
6 GTEx Nerve Tibial RAB5C 0.14 0.08 lasso 8 0.07 1.1e-05 6.8 5.6 2.2e-08 0.95 0.01 0.99 FALSE
7 GTEx Pancreas RAB5C 0.14 0.13 lasso 2 0.08 2.6e-04 6.7 6.7 2.3e-11 1.00 0.00 0.99 FALSE
8 GTEx Stomach RAB5C 0.15 0.10 lasso 3 0.10 2.5e-05 4.6 5.3 1.5e-07 0.90 0.02 0.98 FALSE
9 The Cancer Genome Atlas Thyroid Carcinoma HSPB9 0.05 0.05 lasso 2 0.04 4.7e-05 6.7 6.7 1.6e-11 1.00 0.00 1.00 TRUE