TWAS
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Genes
Traits
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Traits
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Medication: Levothyroxine sodium
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chr19:49,279,612-50,652,095
Best TWAS P=3.11e-07 · Best GWAS P=5.62e-07 conditioned to 0.0134
49.2M
49.4M
49.6M
49.8M
50M
50.2M
50.4M
50.6M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Ovary
ALDH16A1
0.33
0.21
lasso
3
0.15
0.00015
3.6
5.1
3.1e-07
-0.59
0.03
0.45
TRUE