TWAS
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Models
Genes
Traits
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Traits
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Medication: Levothyroxine sodium
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chr22:30,233,446-30,820,707
Best TWAS P=3.89e-08 · Best GWAS P=4.35e-10 conditioned to 0.00161
30.2M
30.3M
30.4M
30.5M
30.6M
30.7M
30.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Thyroid Carcinoma
HORMAD2
0.06
0.04
enet
10
0.07
5.7e-07
-6.2
5.5
3.9e-08
-0.94
0.01
0.99
TRUE