TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Medication: Levothyroxine sodium
:
←
→
chr4:148,303,195-150,060,844
Best TWAS P=1.68e-15 · Best GWAS P=1.62e-16 conditioned to 1
148.2M
148.4M
148.6M
148.8M
149M
149.2M
149.4M
149.6M
149.8M
150M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Thyroid
NR3C2
0.24
0.22
lasso
2
0.21
7e-16
-8
-8
1.7e-15
0.98
0.02
0.98
TRUE