[Hub]/) : Traits : Medication: Levothyroxine sodium : ← →

chr3:11,350,553-12,928,762

Best TWAS P=1.65e-08 · Best GWAS P=1.04e-07 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Hypothalamus	TIMP4	0.24	0.10	lasso	4	0.11	1.7e-03	5.3	5.6	1.6e-08	0.97	0.02	0.95	TRUE
4	The Cancer Genome Atlas	Lung Adenocarcinoma	SYN2	0.03	0.02	enet	6	0.02	4.0e-03	5.3	5.6	2.1e-08	0.90	0.01	0.96	FALSE
3	ROSMAP	Brain Pre-frontal Cortex	TIMP4	0.07	0.05	lasso	7	0.06	5.5e-08	4.4	5.3	1.4e-07	0.90	0.05	0.95	FALSE
2	GTEx	Esophagus Gastroesophageal Junction	SYN2	0.23	0.09	lasso	4	0.12	3.3e-05	4.4	5.1	2.9e-07	0.93	0.03	0.96	FALSE