Best TWAS P=1.03e-09 · Best GWAS P=5.25e-07 conditioned to 0.452
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NTR | Blood | ZNF48 | 0.01 | 0.00 | blup | 196 | 0.00 | 2.2e-02 | 3.2 | -6.1 | 1.0e-09 | -0.38 | 0.03 | 0.08 | TRUE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ALDOA | 0.02 | 0.01 | enet | 9 | 0.02 | 9.2e-05 | 4.9 | 5.3 | 1.5e-07 | 0.90 | 0.01 | 0.98 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | FAM57B | 0.04 | 0.01 | blup | 46 | 0.03 | 2.6e-07 | 4.6 | 5.6 | 2.6e-08 | 0.80 | 0.02 | 0.97 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | DOC2A | 0.03 | 0.01 | blup | 47 | 0.02 | 3.8e-03 | 5.0 | -5.4 | 5.2e-08 | -0.92 | 0.01 | 0.66 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | INO80E | 0.07 | 0.03 | blup | 48 | 0.03 | 1.1e-04 | 5.0 | -5.4 | 6.5e-08 | -0.86 | 0.01 | 0.92 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | DOC2A | 0.03 | 0.02 | blup | 48 | 0.03 | 6.1e-04 | 4.4 | -5.1 | 2.9e-07 | -0.94 | 0.02 | 0.83 | FALSE |