Best TWAS P=3.11e-08 · Best GWAS P=1.63e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | P4HA2-AS1 | 0.14 | 0.05 | lasso | 8 | 0.08 | 3.8e-06 | -5.2 | -5.3 | 1.4e-07 | 0.91 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Thyroid | PDLIM4 | 0.05 | 0.02 | enet | 5 | 0.01 | 3.1e-02 | -5.2 | 5.5 | 3.1e-08 | -0.96 | 0.01 | 0.96 | TRUE |
| 3 | METSIM | Adipose | PDLIM4 | 0.05 | 0.04 | lasso | 4 | 0.02 | 2.8e-04 | -5.2 | 5.3 | 1.3e-07 | -0.99 | 0.00 | 0.99 | FALSE |