Hub : Genes

PDLIM4

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1140	0.0310	2.3e-14	0.183	0.131	0.169	0.171	0.175	9.5e-22	1.1e-15	4.6e-20	2.7e-20	8.0e-21
2	GTEx	Cells Transformed fibroblasts	0.0800	0.0370	1.1e-03	0.086	NA	0.052	NA	0.070	4.9e-07	NA	9.2e-05	NA	6.4e-06
3	GTEx	Ovary	0.2500	0.1190	2.0e-03	0.223	NA	0.052	NA	-0.003	3.4e-06	NA	2.1e-02	NA	4.0e-01
4	GTEx	Skin Not Sun Exposed Suprapubic	0.1330	0.0600	1.6e-04	0.080	NA	0.060	NA	0.062	3.6e-05	NA	3.1e-04	NA	2.6e-04
5	GTEx	Skin Sun Exposed Lower leg	0.0920	0.0310	1.2e-08	0.076	NA	0.084	NA	0.087	7.1e-07	NA	2.0e-07	NA	1.0e-07
6	GTEx	Testis	0.1550	0.0670	7.5e-04	0.065	NA	0.052	NA	0.034	7.4e-04	NA	2.5e-03	NA	1.2e-02
7	GTEx	Thyroid	0.0510	0.0320	8.3e-03	0.022	NA	0.013	NA	0.001	8.2e-03	NA	3.1e-02	NA	2.5e-01
8	METSIM	Adipose	0.0500	0.0252	4.0e-04	0.043	0.011	0.019	0.015	0.022	3.7e-07	8.2e-03	7.1e-04	1.9e-03	2.8e-04
9	ROSMAP	Brain Pre-frontal Cortex	0.2502	0.0554	0.0e+00	0.268	0.223	0.253	0.254	0.260	1.9e-34	3.1e-28	2.4e-32	1.7e-32	2.7e-33
10	TCGA	Bladder Urothelial Carcinoma	0.0470	0.0290	5.8e-03	0.012	0.014	0.017	NA	0.015	3.3e-02	2.0e-02	1.2e-02	NA	1.7e-02
11	TCGA	Breast Invasive Carcinoma	0.0518	0.0228	2.3e-09	0.054	0.046	0.039	NA	0.051	3.0e-11	8.0e-10	1.3e-08	NA	9.0e-11
12	TCGA	Colon Adenocarcinoma	0.1410	0.0750	7.7e-05	0.044	0.082	0.090	NA	0.063	1.5e-03	1.8e-05	6.8e-06	NA	1.7e-04
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0860	0.0490	1.3e-04	0.025	0.017	0.043	NA	0.047	7.8e-04	4.6e-03	1.1e-05	NA	4.5e-06
14	TCGA	Brain Lower Grade Glioma	0.0642	0.0367	4.9e-03	0.001	0.019	0.015	NA	0.006	2.1e-01	2.6e-03	7.2e-03	NA	5.7e-02
15	TCGA	Liver Hepatocellular Carcinoma	0.0760	0.0460	5.6e-03	0.031	0.049	0.027	NA	0.030	1.3e-02	2.4e-03	2.0e-02	NA	1.4e-02
16	TCGA	Prostate Adenocarcinoma	0.3216	0.0762	0.0e+00	0.358	0.357	0.367	NA	0.366	5.2e-39	7.3e-39	3.8e-40	NA	5.9e-40

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Bipolar Disorder (2018)	0.8	1.3	9.3	-0.3	-0.3	-1.3	1.5	1.0	-1.0	0.2	-0.2	-0.3	-1.3	-0.1	0.7	-1.1	-3.0	1.1	-0.3
Bipolar Disorder or Schizophrenia	0.4	0.9	4.8	0.0	-0.1	-0.8	1.7	1.5	-1.0	0.5	0.0	-0.1	-0.7	0.1	1.0	-0.0	-2.2	1.3	0.1
Depressed Affect (Nagel 2018)	0.3	0.6	3.2	-0.1	-0.1	-0.1	-1.4	-0.9	1.3	0.1	0.1	-0.1	0.4	-0.3	-0.4	0.8	1.8	-1.2	-0.1
Depression (Nagel 2018)	0.9	1.3	4.9	-0.9	-0.8	-0.0	-1.7	-1.8	2.2	-0.4	-0.9	-0.8	-0.7	-0.9	-1.0	-0.1	0.7	-1.7	-1.0
Intelligence (Savage-Jansen 2018)	0.2	0.6	2.4	0.4	0.4	-1.1	0.5	0.6	0.6	0.4	0.7	0.4	0.7	0.5	0.5	1.4	1.5	-0.4	0.5
Neuroticism (Nagel 2018)	0.5	1.1	3.6	-0.5	-0.5	-0.2	-1.7	-1.4	1.9	-0.2	-0.4	-0.5	-0.1	-0.7	-0.5	0.4	1.7	-1.9	-0.5
Schizophrenia (2018)	0.1	0.3	1.2	0.3	0.1	-0.0	0.9	1.1	-0.5	0.4	0.2	0.2	0.2	0.3	0.7	0.8	-0.4	0.7	0.3
Schizophrenia vs Biploar Disorder	1.3	1.7	4.5	1.3	1.3	-0.3	1.3	1.1	-0.4	1.1	1.1	1.3	1.8	1.3	0.6	2.0	2.1	0.7	1.6
Worry (Nagel 2018)	0.4	0.9	2.6	-0.7	-0.6	0.8	-1.2	-1.3	1.4	-0.9	-1.0	-0.8	-0.6	-0.7	-0.6	-0.4	0.7	-1.6	-0.9
Alzheimer’s Disease (in mother)	0.3	0.3	0.8	0.8	0.7	-0.1	-0.0	0.8	0.3	0.1	-0.3	0.6	0.5	0.6	0.3	0.9	0.3	0.6	0.8
Alzheimer’s Disease (in father)	0.3	0.3	0.9	-0.9	-0.9	0.2	-0.1	0.1	0.2	0.0	-0.2	-0.8	-0.7	-0.9	0.0	-0.3	-0.1	-0.9	-0.8
Alzheimer’s Disease (including proxy)	0.2	0.2	1.2	-0.4	-0.3	0.0	0.0	0.3	1.1	-0.4	-0.8	-0.5	-0.6	-0.4	0.3	0.4	-0.1	-0.5	-0.2
Crohns Disease (2017)	24.4	53.5	121.0	-6.2	-6.2	8.3	-11.0	-10.6	6.2	-8.5	-7.0	-6.6	-3.0	-7.2	-9.3	-6.6	0.6	-6.1	-6.9
Irritable Bowel Disease (IBD)	18.1	43.1	89.5	-5.8	-5.8	7.0	-9.5	-9.2	5.0	-7.2	-6.1	-6.1	-3.1	-6.8	-8.9	-6.0	-0.1	-5.8	-6.5
Ulcerative Colitis (UC)	5.3	9.9	22.9	-3.0	-3.1	3.0	-3.9	-4.0	1.8	-3.0	-2.6	-3.2	-1.9	-3.6	-4.8	-3.0	-0.9	-3.1	-3.5
Major Depression (MDD)	0.6	0.7	2.0	-0.8	-0.9	0.4	-1.4	-0.6	0.1	-0.4	-0.7	-0.9	-0.6	-1.2	-1.3	-0.8	-0.6	-0.7	-0.9
Reaction Time	0.3	0.5	3.0	-0.5	-0.5	1.7	-0.6	-0.2	0.0	-0.5	-0.4	-0.5	-1.0	-0.7	-0.7	-0.8	-1.0	-0.5	-0.5
Verbal and Numeric Reasoning (VNR)	0.7	1.6	3.6	1.1	1.1	-1.8	1.2	1.2	-0.7	1.4	1.9	1.3	1.1	1.1	0.9	1.6	1.5	0.0	1.2
Breast Cancer	5.7	13.8	27.7	4.1	3.9	-1.8	3.9	5.3	-3.1	4.2	3.9	4.2	2.7	3.9	3.5	3.9	0.7	3.9	4.2
Ovarian Cancer	0.6	0.8	1.3	0.9	0.9	-1.0	0.9	0.6	-0.3	0.9	1.1	0.9	1.1	0.9	1.0	0.7	1.1	1.1	0.9
Prostate Cancer	0.1	0.2	0.5	-0.5	-0.4	-0.4	-0.2	-0.4	0.3	-0.4	-0.3	-0.5	-0.7	-0.5	0.7	-0.3	0.2	-0.6	-0.1
Age at First Birth	0.4	0.5	3.7	-0.4	-0.3	1.9	-1.2	-0.2	-0.3	-0.4	-0.2	-0.3	-0.7	-0.5	-0.5	-0.7	-1.0	-0.2	-0.4
Bipolar Disorder (2011)	0.2	0.2	1.2	-0.2	-0.1	-1.0	-0.0	-0.1	0.3	-0.1	-0.5	-0.3	-0.3	-0.1	-0.2	-1.1	-0.8	0.1	-0.1
Body Mass Index (BMI) (2010)	0.2	0.3	2.0	-0.3	-0.3	0.6	0.4	0.4	-0.6	0.2	-0.2	-0.3	-0.4	-0.1	-0.0	-0.8	-1.4	0.5	-0.3
Coronary Artery Disease (CAD)	0.1	0.1	0.6	-0.0	0.2	0.5	0.4	0.3	-0.3	-0.4	-0.8	-0.2	-0.1	-0.0	-0.2	-0.8	-0.3	0.5	-0.2
Crohns Disease (2012)	17.4	27.9	62.9	-4.4	-4.6	5.2	-7.9	-7.8	4.8	-6.2	-5.0	-5.0	-1.9	-5.2	-6.8	-4.8	0.8	-4.2	-5.0
Mean Putamen Volume	1.5	1.7	3.2	-1.3	-1.6	0.9	-0.8	-1.1	0.7	-1.3	-1.0	-1.3	-1.8	-1.2	-0.7	-1.8	-1.8	-1.2	-1.5
Fasting Glucose	1.8	2.2	3.4	-1.8	-1.6	1.6	-0.9	-1.3	0.6	-0.8	-1.8	-1.5	-1.6	-1.8	-1.5	-1.7	-1.1	-1.2	-1.7
HbA1C	0.3	0.3	1.4	-0.4	-0.7	-0.5	-0.5	-0.0	-0.0	-1.2	-0.1	-0.8	-0.4	-0.6	-0.3	-0.1	-0.9	-0.2	-0.5
HDL Cholesterol	1.7	2.8	5.1	-2.0	-2.0	0.6	-1.4	-1.2	1.6	-1.3	-1.5	-1.9	-2.2	-2.0	-1.2	-1.1	-1.5	-2.2	-1.8
LDL Cholesterol	0.4	0.7	1.6	-0.6	-0.7	0.7	-1.2	-1.2	0.1	-1.0	-0.9	-0.5	-0.5	-0.3	-0.5	-1.3	0.3	-0.9	-1.0
Lupus	1.8	2.7	7.0	-1.5	-1.7	1.1	-2.6	-2.3	1.5	-1.6	-1.4	-1.6	-0.7	-1.9	-1.7	-0.9	0.9	-2.1	-1.4
Neuroticism (2016)	0.3	0.4	2.0	0.1	0.0	0.6	-0.8	-0.2	0.2	0.7	1.0	0.2	0.3	-0.3	-0.3	1.3	1.4	-0.8	-0.1
Primary Biliary Cirrhosis	0.1	0.1	0.4	0.2	0.2	-0.1	0.4	0.0	-0.7	-0.3	0.2	0.1	0.3	0.4	0.6	0.0	-0.0	0.5	0.4
Rheumatoid Arthritis	0.3	0.4	1.5	-0.5	-0.4	-0.4	1.2	1.1	-0.6	0.6	-0.1	-0.3	-0.5	-0.4	-0.8	-0.0	-1.1	-0.6	-0.2
Schizophrenia (2014)	0.3	0.6	1.8	0.5	0.3	-0.3	1.3	1.2	-1.0	0.6	0.3	0.4	0.1	0.5	0.9	0.8	-0.9	1.1	0.5
Triglycerides	5.0	8.1	11.7	3.1	3.1	-1.4	2.9	3.1	-3.4	3.4	3.0	3.2	3.0	3.0	1.5	2.8	1.7	2.8	3.1
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.4	0.7	0.7	-0.4	0.7	0.8	-0.3	1.0	0.3	1.2	0.7	1.2	-0.1	1.0	0.9	-0.1	0.9
Ulcerative Colitis	4.3	6.3	15.1	-2.1	-2.2	2.5	-3.8	-3.7	1.1	-2.3	-2.1	-2.3	-0.9	-2.8	-3.9	-2.4	0.5	-2.3	-2.4
Blood Eosinophil Count	56.4	434.3	998.6	17.4	17.4	-16.8	25.4	30.3	-26.9	31.6	26.2	19.9	10.1	17.2	16.9	20.0	-0.5	16.0	18.8
Blood Platelet Count	11.1	128.9	225.0	10.9	10.7	-6.7	13.4	15.0	-13.6	14.6	14.1	12.0	8.9	10.8	8.9	10.6	3.6	9.8	11.9
Blood Red Count	0.2	2.0	3.7	1.6	1.6	-0.8	1.4	1.9	-1.0	1.9	1.2	1.6	1.4	1.5	1.0	0.9	0.4	1.5	1.7
Blood White Count	19.6	145.0	259.2	12.3	12.2	-8.3	13.6	16.1	-11.7	14.8	13.1	12.9	10.5	12.3	9.0	12.0	4.2	11.7	13.1
Heel T-Score	1.0	7.8	11.2	3.2	3.1	-2.8	2.8	2.7	-1.5	2.9	2.8	3.2	3.2	3.2	2.1	2.5	2.1	2.5	3.4
BMI	0.6	3.7	7.3	2.1	2.1	-1.2	1.4	1.7	-1.8	2.7	2.4	2.2	1.7	2.3	1.8	0.5	0.1	2.7	2.1
Height	16.0	308.6	503.8	-17.4	-17.0	12.1	-19.2	-22.4	19.9	-22.4	-21.7	-18.7	-15.2	-17.1	-12.9	-17.2	-7.3	-14.7	-18.8
Waist Hip Ratio (WHR)	0.6	2.9	7.1	-1.9	-1.8	-0.5	-1.0	-2.7	1.5	-2.1	-2.1	-1.9	-1.3	-1.8	-1.6	-1.5	-0.6	-1.8	-1.8
Systolic Blood Pressure	0.3	1.5	3.3	1.4	1.4	-0.5	1.7	1.5	-1.8	0.7	0.7	1.3	1.2	1.5	0.9	0.5	0.6	1.3	1.3
Smoking Status	0.2	0.4	2.4	-0.2	-0.2	0.5	-1.5	-1.5	0.5	-0.7	-0.3	-0.2	0.2	-0.3	-0.3	-0.2	0.9	-0.1	-0.4
Allergy or Eczema	4.5	11.7	27.9	3.0	2.9	-5.1	4.2	4.4	-3.3	5.3	3.6	3.2	1.6	3.2	2.9	3.2	0.1	2.1	3.1
Cardiovascular Disease	2.6	8.7	17.3	2.6	2.5	-3.7	4.2	4.0	-2.6	3.8	3.0	2.7	1.3	2.8	3.4	2.7	0.5	2.3	2.7
Hypothyroidism (self reported)	3.6	8.2	12.0	-3.5	-3.4	2.6	-2.4	-2.6	1.2	-2.5	-2.4	-3.2	-2.7	-3.5	-3.3	-2.9	-2.0	-3.2	-3.3
Respiratory disease	22.5	50.2	80.4	7.2	7.1	-8.0	8.8	8.9	-4.8	9.0	6.3	7.1	4.8	7.3	6.8	8.4	2.0	5.9	7.4
Type 2 Diabetes (T2D) (2018)	0.3	0.6	1.9	1.0	1.1	-0.3	0.3	0.9	-0.7	0.4	0.2	0.9	0.8	1.0	-0.0	0.6	0.1	1.4	0.7
Lung FEV1/FVC ratio	7.1	35.8	74.3	-6.3	-6.3	6.0	-8.6	-8.4	2.5	-5.2	-3.1	-5.9	-3.0	-6.7	-7.2	-5.9	1.8	-7.1	-6.4
Lung FVC	4.1	20.6	54.3	2.9	2.8	-4.8	7.4	7.3	-5.4	6.2	5.8	3.7	1.5	3.2	4.0	3.5	-1.7	2.8	4.0
Neuroticism	0.3	0.7	2.7	-0.5	-0.5	0.4	-1.2	-1.2	1.2	-0.3	-0.2	-0.5	-0.0	-0.8	-0.9	0.2	1.4	-1.6	-0.6
Chronotype (morning person)	1.6	3.8	9.5	1.9	2.0	-3.1	2.3	1.9	-0.2	1.6	1.4	2.0	1.5	2.4	2.5	2.1	1.1	1.6	2.0
Hair Pigment	0.0	0.4	2.8	0.4	0.5	0.1	1.1	0.8	-0.6	0.0	-0.7	0.2	-0.6	0.1	-0.3	0.0	-1.7	0.2	-0.2
Tanning	0.0	0.2	1.0	-0.1	-0.2	0.1	0.1	0.3	0.6	-0.7	-1.0	-0.4	0.1	0.2	0.5	-0.3	-0.4	0.5	0.2
Hand grip strength (left)	15.0	39.4	58.7	-6.4	-6.4	6.0	-7.5	-7.7	5.8	-7.5	-7.0	-6.7	-5.1	-6.7	-4.8	-6.3	-2.2	-5.4	-6.8
Number of treatments/medications taken	5.7	10.3	16.0	3.3	3.3	-3.0	3.2	4.0	-3.5	4.0	3.4	3.4	2.4	3.3	2.6	3.5	1.4	2.6	3.4
Average weekly spirits intake	0.3	0.4	1.2	0.5	0.5	-1.1	0.2	0.2	0.4	0.5	0.7	0.6	0.5	0.8	0.9	0.8	0.4	0.2	0.5
Sensitivity / hurt feelings	1.0	1.7	3.9	-1.2	-1.3	0.7	-1.8	-1.8	1.0	-0.7	-0.7	-1.1	-0.5	-1.5	-1.7	-0.8	1.1	-2.0	-1.5
Frequency of depressed mood in last 2 weeks	2.0	2.8	7.4	-1.5	-1.4	0.4	-2.7	-2.6	1.8	-1.3	-1.8	-1.5	-1.3	-1.6	-1.7	-0.9	0.4	-2.1	-1.8
Hearing difficulty/problems: Yes	0.2	0.4	1.4	0.5	0.3	-1.2	0.8	0.9	0.2	0.9	0.6	0.4	0.1	0.5	0.7	0.3	-0.2	0.4	0.6
Relative age of first facial hair	1.8	3.8	9.4	2.1	2.1	-1.9	2.3	2.6	-0.4	2.1	1.1	2.0	1.3	2.1	1.6	3.1	0.5	1.8	2.0
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.8	0.9	0.9	-0.4	1.0	0.9	-1.2	1.1	1.0	0.9	1.3	0.9	-0.2	1.1	0.8	0.9	1.1
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.4	-0.0	-0.1	-0.5	0.5	0.3	-0.3	0.1	-0.0	-0.1	-0.1	0.2	-0.3	-0.2	-0.6	-0.2	-0.0
Ever had hysterectomy (womb removed)	0.7	0.7	1.9	-1.2	-1.2	0.1	0.5	-0.3	-1.0	0.0	-0.0	-1.0	-0.7	-1.0	-1.2	-0.9	-0.6	-1.4	-0.9
Systolic blood pressure, automated reading	0.2	0.6	1.8	0.9	0.8	-0.1	0.7	0.4	-0.2	-0.0	0.2	0.7	1.3	1.1	0.3	0.4	1.2	0.8	0.9
Eye problems/disorders: Diabetes related eye disease	1.1	1.3	2.6	-1.1	-1.1	1.1	-1.6	-1.5	0.8	-1.5	-1.1	-1.2	-0.7	-1.2	-1.0	-0.9	-0.6	-0.5	-1.3
Angina	1.8	2.4	4.5	2.0	1.8	-1.6	1.2	1.5	-0.2	1.6	1.1	1.7	1.8	1.8	0.4	2.1	1.5	1.6	1.6
Medication for hormone replacement therapy	2.4	2.7	4.6	2.0	2.1	-1.6	1.0	1.0	-1.2	1.5	1.2	2.0	2.1	2.1	1.3	1.1	1.3	1.9	1.9
Vitamin and mineral supplements	1.4	2.0	3.8	1.5	1.4	-1.2	1.2	1.2	-0.5	1.5	1.6	1.5	1.4	1.5	1.9	1.3	1.1	1.4	1.7
Supplements: Zinc	1.4	1.5	3.8	-1.4	-1.2	-0.8	-0.3	-1.1	0.4	-1.5	-1.8	-1.4	-1.4	-0.8	-0.4	-2.0	-1.6	-0.9	-1.4
Medication: Co-codamol	1.0	1.1	2.1	1.4	1.4	-0.0	-0.1	0.1	0.7	0.4	0.6	1.2	1.4	1.2	0.8	1.4	1.4	1.4	1.2
Medication: Metformin	1.0	1.4	4.0	1.5	1.5	-0.8	0.8	1.4	-1.7	0.8	0.7	1.4	1.0	1.4	0.8	0.5	-0.0	2.0	1.2
Diabetes (father)	0.6	0.7	3.0	0.8	0.7	0.2	-0.2	0.1	-1.0	0.7	0.5	0.7	1.4	0.8	0.4	1.0	1.7	0.5	0.7
Diabetes (mother)	0.2	0.2	1.8	0.3	0.4	-0.5	0.3	0.7	-1.3	0.7	0.1	0.3	-0.1	0.2	0.4	-0.0	-0.2	-0.0	0.3
Severe depression (siblings)	0.4	0.4	1.5	0.7	0.7	-0.7	0.6	0.6	-0.4	1.2	0.7	0.7	0.4	0.6	0.4	0.3	-0.2	0.7	0.7
Pack years adult smoking proportion	0.8	1.2	3.9	-0.5	-0.5	0.3	-1.6	-1.5	2.0	-1.2	-1.7	-0.8	-0.1	-0.5	-1.8	-0.3	0.7	-1.0	-0.7
Impedance of leg (right)	0.4	1.9	9.7	0.2	0.1	-2.8	3.1	2.4	-1.9	0.8	0.6	0.2	-0.2	0.3	0.4	0.7	-1.2	0.5	0.5
Leg fat-free mass (left)	8.3	43.8	80.8	-6.2	-6.1	5.4	-8.3	-9.0	7.7	-7.9	-7.9	-6.7	-5.5	-6.1	-4.4	-7.1	-2.4	-5.1	-7.0
Trunk fat percentage	0.1	0.2	1.1	-0.3	-0.3	-0.3	-0.3	-0.2	0.2	-0.2	-0.4	-0.4	-0.5	-0.1	-0.1	-1.0	-1.0	0.4	-0.4
Hand grip strength (right)	17.1	46.3	68.8	-7.2	-7.1	5.9	-7.6	-8.3	5.8	-8.0	-7.4	-7.3	-5.5	-7.4	-5.6	-7.5	-2.2	-6.2	-7.5
Townsend deprivation index at recruitment	0.1	0.1	0.3	0.2	0.3	0.2	0.3	0.5	-0.3	0.0	-0.1	0.2	0.0	0.3	-0.1	0.0	-0.6	0.2	0.2
Current tobacco smoking	0.5	0.9	2.3	-0.6	-0.5	0.3	-1.5	-1.5	1.0	-0.9	-1.2	-0.7	-0.0	-0.6	-1.5	-0.8	0.8	-0.7	-0.7
Average weekly fortified wine intake	1.2	1.4	3.7	-1.4	-1.4	-0.3	-0.3	-1.0	0.5	-0.8	-0.8	-1.3	-1.6	-1.1	-1.0	-1.9	-1.6	-1.1	-1.1
Maternal smoking around birth	0.6	0.8	3.2	-0.5	-0.5	-1.6	0.1	-0.6	1.8	-1.2	-1.4	-0.8	-0.2	-0.3	-0.8	-0.2	0.5	-0.8	-0.5
Fed-up feelings	0.4	0.8	3.2	-0.4	-0.4	-0.2	-1.4	-1.1	1.2	-0.3	-0.3	-0.4	0.4	-0.6	-1.2	0.2	1.8	-1.4	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	1.6	2.2	5.3	-1.6	-1.4	0.2	-1.4	-1.6	1.9	-0.7	-1.6	-1.5	-1.4	-1.5	-2.0	-0.5	-0.3	-2.3	-1.6
Relative age voice broke	0.5	0.7	3.0	-0.2	-0.2	-1.7	1.4	1.3	-0.2	0.7	-0.1	-0.2	-1.0	-0.3	0.2	0.7	-1.4	-0.3	-0.1
Taking other prescription medications	3.3	5.1	7.2	2.3	2.4	-2.1	2.3	2.6	-2.7	2.6	2.1	2.4	1.9	2.4	1.3	2.6	0.9	2.0	2.5
Age when periods started (menarche)	4.6	11.0	18.0	-3.5	-3.4	3.9	-3.5	-3.7	2.0	-3.3	-3.1	-3.4	-2.6	-3.8	-4.2	-3.4	-0.9	-3.3	-3.4
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	2.6	-1.2	-1.2	1.1	-1.4	-1.0	0.4	-0.6	-1.2	-1.2	-0.9	-1.2	-1.2	-0.9	-0.3	-1.6	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	0.7	0.4	0.3	-0.6	-0.3	0.3	0.6	-0.0	-0.0	0.3	0.4	0.4	0.5	0.5	0.9	-0.2	0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.7	-0.1	-0.1	-0.1	-0.4	-0.5	0.5	-0.8	-0.7	-0.2	0.0	0.2	-0.0	-0.3	0.1	0.2	-0.2
Qualifications: CSEs or equivalent	0.8	1.1	1.8	-1.2	-1.2	-0.7	-0.5	-0.9	1.3	-1.1	-1.2	-1.2	-1.1	-1.1	-0.5	-1.0	-1.0	-0.8	-1.3
Serious illness, injury or assault to yourself	0.3	0.4	1.5	-0.5	-0.5	-0.2	-0.3	-0.9	1.2	-0.9	-0.8	-0.6	-0.7	-0.4	-0.3	-0.5	-0.6	-0.4	-0.6
High blood pressure	7.5	21.0	32.3	4.8	4.6	-4.1	5.4	5.7	-4.0	5.4	4.9	4.8	3.8	4.9	4.1	4.1	1.4	4.6	5.0
Hayfever, allergic rhinitis or eczema	6.1	13.2	30.9	2.8	2.8	-5.6	5.2	5.1	-4.3	5.3	3.7	3.1	1.3	3.0	2.9	2.9	-0.6	2.1	3.1
Multivitamins +/- minerals	1.1	1.4	2.5	-1.3	-1.3	1.2	-1.2	-1.2	0.5	-1.3	-1.4	-1.3	-1.0	-1.4	-1.3	-1.0	-0.5	-1.2	-1.6
Stomach or abdominal pain in last month	3.0	3.8	8.5	-1.7	-1.8	1.3	-2.9	-2.4	1.6	-2.2	-2.2	-1.9	-1.4	-1.8	-2.3	-1.9	-0.8	-2.2	-1.8
Supplements: Glucosamine	0.1	0.1	0.5	0.0	-0.0	0.4	-0.6	-0.4	-0.1	-0.6	-0.3	-0.1	-0.2	0.1	0.4	-0.3	-0.7	-0.0	0.0
Diverticular disease/diverticulitis (self-reported)	0.4	0.4	3.1	-0.1	-0.2	0.1	-1.1	-0.6	1.8	-1.0	-0.9	-0.4	-0.1	-0.2	0.1	-0.1	-0.1	0.0	-0.2
Medication: Atenolol	2.3	2.9	5.2	1.9	1.7	-0.5	1.4	2.3	-2.0	2.1	2.1	1.8	1.5	1.6	1.3	1.7	0.3	2.2	1.7
Medication: Levothyroxine sodium	2.3	3.8	6.6	-2.5	-2.4	1.5	-1.7	-1.8	0.3	-1.1	-1.1	-2.2	-2.0	-2.6	-2.4	-2.2	-1.6	-2.3	-2.3
Sitting height	8.1	57.3	104.0	-7.4	-7.4	5.1	-8.8	-10.2	8.4	-9.5	-9.1	-8.0	-6.1	-7.4	-4.7	-8.3	-2.2	-6.6	-7.9
Chronic bronchitis/emphysema (father)	2.0	2.4	3.5	1.8	1.8	-0.6	1.1	1.9	-1.9	1.7	1.6	1.8	1.6	1.4	0.8	1.7	0.6	1.7	1.6
High blood pressure (mother)	2.2	3.1	5.5	1.7	1.8	-1.5	1.7	2.2	-1.4	2.4	2.3	2.0	1.2	1.7	1.7	1.9	-0.1	1.8	1.8
Body mass index (BMI)	0.8	3.6	6.1	2.3	2.3	-1.2	1.1	1.8	-0.9	2.2	2.0	2.2	1.7	2.5	2.1	1.3	0.6	2.4	2.2
Impedance of leg (left)	0.9	4.5	16.8	1.4	1.3	-3.1	4.1	3.5	-2.8	1.8	1.7	1.4	0.9	1.4	1.4	1.9	-0.5	1.3	1.8
Leg predicted mass (left)	8.2	43.6	80.3	-6.2	-6.1	5.4	-8.2	-9.0	7.6	-7.8	-7.8	-6.7	-5.5	-6.1	-4.4	-7.1	-2.4	-5.2	-6.9
Trunk fat mass	1.1	4.7	8.7	-2.0	-2.0	1.1	-2.6	-2.9	2.5	-2.5	-2.6	-2.3	-2.1	-1.9	-1.2	-3.0	-1.5	-1.1	-2.4
Waist circumference	0.3	1.3	3.6	-0.8	-0.8	-0.0	-1.5	-1.9	1.5	-1.2	-1.4	-1.0	-0.9	-0.6	-0.6	-1.7	-0.9	-0.1	-1.1
Number of incorrect matches in round	0.4	0.7	5.6	-0.4	-0.2	2.4	-1.4	-0.4	0.4	-0.8	-0.7	-0.3	-0.3	-0.7	-1.1	-0.2	0.1	-0.5	-0.6
Past tobacco smoking	1.3	2.3	3.7	-1.6	-1.7	1.4	-1.6	-1.2	0.9	-1.3	-1.7	-1.7	-1.1	-1.7	-1.9	-1.9	-0.4	-1.8	-1.6
Alcohol usually taken with meals	0.1	0.2	0.7	0.5	0.5	0.3	-0.0	0.2	-0.5	0.5	0.7	0.6	0.3	0.5	0.6	0.1	-0.1	0.8	0.3
Nervous feelings	0.4	0.8	1.7	1.1	1.1	-1.1	0.7	1.0	-0.3	1.1	1.0	1.1	0.4	1.0	0.7	1.3	0.3	0.2	0.9
Frequency of tenseness / restlessness in last 2 weeks	2.4	3.8	7.8	-1.6	-1.5	1.2	-2.8	-2.6	2.7	-2.5	-2.7	-1.8	-1.3	-1.6	-1.2	-1.3	0.2	-2.0	-1.9
Hearing difficulty/problems with background noise	0.5	0.8	2.0	0.7	0.7	-0.8	0.9	1.2	-1.4	1.3	1.2	0.8	0.6	0.7	0.6	0.3	0.3	0.3	1.0
Hair/balding pattern: Pattern 2	3.5	4.5	7.4	-2.0	-2.1	1.6	-2.2	-2.4	2.7	-2.5	-2.5	-2.3	-2.1	-2.0	-1.6	-1.5	-0.7	-2.6	-2.1
Had menopause	0.4	0.4	1.8	0.8	0.8	-0.1	0.2	0.2	1.4	-0.7	-0.6	0.4	0.2	0.9	0.6	0.6	-0.3	0.9	0.5
Had other major operations	0.8	1.0	2.4	-1.1	-1.0	0.8	-0.9	-1.1	0.0	-0.6	-0.7	-0.9	-1.0	-0.9	-1.4	-1.5	-0.9	-1.5	-0.9
Forced vital capacity (FVC)	1.6	6.0	9.2	-2.7	-2.6	1.2	-1.7	-2.5	2.5	-3.0	-2.8	-2.7	-3.0	-2.6	-0.5	-3.0	-2.4	-1.9	-2.7
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	1.7	0.5	0.4	-0.7	-0.1	0.4	-0.2	0.3	0.4	0.5	0.7	0.5	0.2	0.5	1.3	-0.4	0.5
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	2.1	-0.0	-0.1	-1.4	0.6	0.3	-0.8	0.8	0.6	0.1	0.0	0.1	0.3	0.1	0.2	-0.3	-0.0
Qualifications: None of the above	0.7	1.4	5.7	-1.0	-1.0	2.4	-1.5	-0.5	-0.5	0.2	0.0	-0.8	-0.4	-1.4	-2.4	-0.2	0.5	-1.4	-1.0
Financial difficulties in last 2 years	0.7	1.0	2.2	-0.9	-0.9	-0.0	-1.5	-1.5	0.8	-1.3	-1.2	-1.0	-0.6	-0.9	-0.8	-1.1	0.1	-0.8	-1.1
Mouth/teeth dental problems	0.6	0.9	6.4	0.8	0.8	-0.9	1.2	0.4	-0.4	-0.2	-0.1	0.7	-0.0	1.1	2.5	-0.1	-0.5	1.1	0.7
Heart attack	2.3	3.0	5.2	2.3	2.2	-0.8	1.3	2.0	-0.8	1.3	1.1	2.0	1.6	2.2	1.6	2.1	0.6	2.3	2.0
Allergy	14.5	33.3	59.1	-5.5	-5.5	7.3	-7.4	-7.7	5.1	-7.5	-5.5	-5.7	-3.4	-5.6	-5.2	-5.7	-0.7	-4.7	-5.7
Pain all over the body in last month	0.6	0.6	2.6	-0.5	-0.4	1.1	-1.6	-1.2	0.1	0.0	-0.2	-0.3	-0.1	-0.8	-1.2	0.4	1.1	-0.8	-0.6
Diabetes (self-reported)	0.3	0.5	2.1	0.8	0.8	-1.2	0.4	0.7	-0.7	0.2	-0.0	0.7	0.4	0.8	0.0	0.1	-0.6	1.4	0.6
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	6.7	0.9	0.8	-1.8	2.6	2.1	-1.6	2.0	1.4	1.0	0.2	1.0	1.2	0.7	-0.7	0.7	1.0
Medication: Ramipril	2.8	3.6	5.8	2.2	2.2	-0.9	1.8	2.0	-1.6	1.9	1.8	2.2	2.3	2.2	0.9	1.6	1.5	2.0	2.4
Medication: Simvastatin	0.0	0.1	0.3	-0.1	-0.2	-0.1	-0.5	0.2	0.3	0.2	0.0	-0.1	-0.4	-0.3	-0.1	0.3	0.0	-0.3	-0.4
Fluid intelligence score	0.7	1.4	4.1	1.1	1.1	-1.0	0.8	0.9	-0.4	1.0	1.4	1.2	1.1	1.1	0.8	2.0	2.0	0.1	1.1
Illnesses of siblings	2.6	3.6	7.2	-1.9	-1.9	1.8	-1.9	-2.3	2.4	-2.7	-2.3	-2.2	-1.7	-2.0	-0.8	-1.3	-0.6	-1.2	-2.0
Neuroticism score	0.3	0.7	2.9	-0.4	-0.4	0.3	-1.4	-1.2	1.0	-0.2	-0.2	-0.4	-0.3	-0.8	-0.9	0.3	0.9	-1.7	-0.8
Weight	3.5	17.1	33.8	-3.7	-3.6	3.0	-5.3	-5.8	5.3	-5.0	-5.1	-4.1	-3.4	-3.5	-2.3	-4.8	-1.6	-2.7	-4.2
Impedance of arm (right)	0.3	1.4	2.7	-1.5	-1.4	0.1	0.0	-1.0	-0.3	-1.5	-1.2	-1.4	-1.0	-1.5	-1.7	-1.2	-0.9	-1.2	-1.4
Arm fat percentage (right)	0.7	2.7	4.6	1.8	1.7	-1.9	1.3	1.6	-1.4	2.1	1.9	1.8	1.4	2.0	1.6	0.6	0.2	2.1	1.7
Trunk fat-free mass	7.9	45.5	88.2	-6.4	-6.2	5.2	-8.3	-9.4	8.2	-8.2	-8.2	-6.9	-5.5	-6.2	-4.0	-7.1	-2.0	-5.3	-7.0
Hip circumference	0.2	0.7	2.1	-0.2	-0.2	0.8	-1.3	-1.3	1.2	-0.9	-1.1	-0.4	-0.7	-0.0	0.4	-1.4	-0.9	0.4	-0.6
Time employed in main current job	0.3	0.3	0.8	-0.7	-0.7	-0.5	-0.3	-0.2	-0.9	0.2	0.2	-0.6	-0.5	-0.6	-0.5	-0.8	-0.8	-0.3	-0.5
Alcohol intake versus 10 years previously	1.0	1.5	8.3	-1.2	-1.1	0.7	0.3	0.3	-0.1	-0.1	-0.6	-1.1	-2.2	-1.1	0.2	-1.4	-2.9	-0.8	-1.2
Father’s age at death	5.6	7.5	15.5	-2.3	-2.3	2.9	-3.9	-3.9	3.4	-3.9	-3.0	-2.6	-1.1	-2.6	-2.0	-2.3	0.7	-2.1	-2.3
Worrier / anxious feelings	0.3	0.5	1.7	-0.5	-0.4	0.2	-1.1	-1.2	0.5	-0.4	-0.2	-0.4	0.0	-0.7	-1.3	0.0	1.1	-1.0	-0.8
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	5.0	-1.1	-1.0	0.8	-2.2	-1.9	1.3	-0.9	-1.1	-1.0	-1.1	-1.3	-1.3	-0.3	0.8	-2.2	-1.4
Falls in the last year	0.6	0.8	2.3	-1.1	-1.0	0.1	-0.5	-0.4	0.0	-0.6	-0.8	-1.1	-1.0	-1.1	-1.5	-1.0	-1.3	-0.6	-0.9
Hair/balding pattern: Pattern 3	2.5	3.7	13.2	0.9	1.0	-2.6	2.6	2.5	-3.6	2.5	2.6	1.3	1.1	1.1	0.8	0.4	-0.8	2.0	1.4
Number of live births	0.3	0.4	0.9	-0.4	-0.5	0.9	-1.0	-0.8	0.8	-0.9	-0.6	-0.5	0.3	-0.5	-0.6	-0.3	-0.0	0.3	-0.4
Forced expiratory volume in 1-second (FEV1)	4.0	13.6	20.2	-4.2	-4.1	2.4	-3.8	-4.5	2.8	-4.1	-3.5	-4.1	-3.7	-4.2	-2.4	-4.5	-2.0	-3.4	-4.3
Pulse rate	0.0	0.0	0.1	-0.0	-0.1	0.0	0.0	-0.3	0.0	-0.3	0.1	-0.0	0.1	0.0	-0.1	-0.2	-0.2	-0.1	-0.2
Happiness	2.0	2.4	4.9	-1.2	-1.1	2.2	-2.1	-1.6	1.7	-2.1	-2.0	-1.3	-1.5	-1.4	-1.3	-0.6	-0.0	-1.6	-1.7
Noisy workplace	2.3	2.9	7.3	1.6	1.5	-2.7	2.5	2.0	-0.1	1.1	0.9	1.4	0.6	2.0	2.5	1.1	-0.9	2.0	1.7
Qualifications: A levels/AS levels or equivalent	0.5	1.2	5.7	1.0	1.0	-1.6	1.4	0.8	0.1	0.1	0.2	0.8	0.6	1.3	2.4	0.5	-0.1	1.4	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	3.1	0.1	0.2	0.4	-1.8	-1.3	1.4	-1.1	-0.5	0.0	0.3	-0.1	0.4	0.5	1.7	-0.2	-0.3
Mouth/teeth dental problems: Dentures	0.3	0.5	4.4	-0.0	-0.1	0.2	-0.4	-0.2	2.1	-0.1	-0.4	-0.2	0.5	-0.1	-1.4	0.9	0.7	-0.1	-0.0
Asthma	27.7	54.6	89.7	7.7	7.6	-8.0	8.4	9.0	-5.6	9.5	7.2	7.8	5.4	7.6	6.4	8.5	2.8	6.0	7.8
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.8	-0.6	-0.4	1.2	-0.8	-0.5	1.0	-1.3	-1.0	-0.5	-0.7	-0.4	-0.2	-0.5	-0.1	-0.5	-0.6
Medication: Cholesterol lowering	1.2	1.9	3.7	1.5	1.5	-0.4	1.1	1.9	-1.8	1.7	1.5	1.5	0.7	1.5	1.2	1.4	0.2	1.4	1.2
Depression (self-reported)	0.2	0.3	2.9	0.2	0.2	-1.7	-0.0	-0.5	-0.7	0.8	0.2	0.2	0.2	0.2	0.0	-0.4	-0.1	-0.1	0.3
Medication: Lansoprazole	0.1	0.1	0.9	0.3	0.3	0.0	-0.1	-0.0	0.9	-0.3	-0.6	0.1	-0.1	0.3	-0.2	0.1	-0.2	-0.5	0.3
Prospective memory result	0.7	0.8	1.9	0.7	0.6	-0.8	1.3	1.4	-0.8	1.2	1.2	0.8	0.3	0.9	1.1	0.7	-0.3	0.5	0.8
Lung cancer (father)	0.8	0.9	4.0	-0.3	-0.3	1.2	-2.0	-1.6	1.2	-1.0	-1.1	-0.4	-0.1	-0.4	-1.0	-0.2	0.7	-0.6	-0.6
Illnesses of mother	2.4	3.0	6.3	-1.5	-1.5	2.5	-2.4	-2.2	1.1	-2.4	-1.8	-1.6	-1.2	-1.4	-1.3	-2.1	-0.3	-0.8	-1.7
Forced expiratory volume in 1-second (FEV1), Best measure	5.0	16.1	27.0	-4.8	-4.6	2.4	-3.5	-4.5	2.4	-4.2	-3.7	-4.5	-4.2	-4.6	-2.9	-5.2	-2.6	-4.0	-4.6
Pulse wave Arterial Stiffness index	0.3	0.3	1.7	-0.4	-0.3	0.2	-0.3	-1.0	0.1	-0.3	-0.2	-0.3	0.1	-0.3	-1.3	-0.9	0.3	-0.6	-0.4
Impedance of arm (left)	0.7	3.3	5.4	-2.2	-2.2	0.6	-0.3	-1.3	-0.0	-2.0	-1.7	-2.2	-1.8	-2.3	-2.3	-1.8	-1.5	-2.0	-2.2
Arm fat mass (right)	0.3	1.1	3.2	-0.6	-0.6	0.3	-1.7	-1.6	1.7	-1.1	-1.2	-0.8	-0.7	-0.4	-0.1	-1.8	-0.8	0.0	-0.8
Trunk predicted mass	7.9	44.9	88.0	-6.3	-6.2	5.2	-8.3	-9.4	8.1	-8.2	-8.1	-6.8	-5.4	-6.1	-3.9	-7.0	-2.0	-5.3	-7.0
Standing height	16.7	165.3	275.7	-12.9	-12.7	9.4	-14.0	-16.6	13.5	-16.0	-15.5	-13.8	-11.1	-12.9	-9.3	-13.2	-4.9	-11.1	-13.9
Length of working week for main job	0.4	0.5	1.0	0.9	0.9	-0.7	0.8	0.6	0.5	0.4	0.1	0.7	0.4	1.0	0.7	0.5	-0.2	0.9	0.9
Exposure to tobacco smoke at home	0.2	0.2	1.5	0.3	0.3	0.0	-0.6	-0.9	1.2	-0.4	-0.1	0.2	0.4	0.3	0.1	0.3	0.6	0.2	0.2
Breastfed as a baby	0.6	0.7	3.7	-0.6	-0.5	1.9	-1.4	-0.8	0.6	-0.8	-0.5	-0.6	-0.4	-0.7	-0.9	-1.1	-0.5	-0.1	-0.6
Tense / ‘highly strung’	0.5	0.9	4.5	-0.6	-0.7	0.0	-0.9	-1.1	2.1	-0.8	-1.0	-0.8	-0.8	-0.7	-0.5	-0.1	0.0	-1.6	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.9	-1.0	-1.0	-1.0	-0.8	-1.2	1.1	-1.0	-1.1	-1.1	-1.2	-0.8	-0.7	-1.7	-1.3	-0.7	-1.3
Hair/balding pattern: Pattern 4	0.6	1.5	3.9	1.1	1.3	-0.6	1.3	1.2	-2.0	0.8	1.3	1.3	1.2	1.3	0.8	-0.1	-0.4	2.0	1.4
Birth weight of first child	5.3	9.7	14.0	-3.7	-3.6	1.7	-2.5	-3.3	1.9	-3.4	-3.3	-3.6	-3.1	-3.5	-2.6	-3.7	-2.0	-3.1	-3.5
Peak expiratory flow (PEF)	3.7	8.5	13.8	-3.2	-3.1	1.4	-3.3	-3.7	3.0	-3.5	-3.2	-3.2	-2.5	-3.1	-1.9	-3.4	-1.1	-2.4	-3.3
Pulse wave reflection index	1.1	1.3	3.9	0.9	1.0	-0.7	1.4	1.6	-1.6	2.0	1.8	1.2	0.6	0.8	0.1	0.2	-0.1	0.7	1.1
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.0	-0.2	-0.1	-0.6	-0.4	-0.5	0.7	-0.7	-0.7	-0.3	-0.9	0.0	-0.1	-0.3	-1.0	-0.0	-0.5
Loud music exposure frequency	0.5	0.5	2.6	0.4	0.4	-1.6	1.1	1.1	-0.3	0.5	0.0	0.3	-0.2	0.4	0.9	0.4	-0.7	0.6	0.3
Qualifications: O levels/GCSEs or equivalent	0.7	1.1	2.5	-0.8	-0.7	0.5	-0.7	-1.4	1.2	-1.6	-1.2	-0.9	-1.4	-0.3	0.9	-1.2	-1.1	-0.5	-1.0
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	7.0	1.1	1.1	-0.2	1.1	1.4	-2.7	1.6	2.1	1.4	1.3	0.8	0.0	0.8	0.5	1.1	1.1
Blood clot in the leg (DVT)	0.9	1.2	3.0	-0.7	-0.6	1.3	-1.7	-1.6	1.0	-1.6	-1.5	-0.8	-0.3	-0.8	-0.9	-1.2	-0.0	-0.2	-1.0
Medication: Paracetamol	1.2	2.0	4.8	-1.1	-1.1	0.4	-1.6	-1.5	2.2	-2.2	-1.9	-1.4	-1.4	-1.1	-0.7	-1.3	-0.2	-1.4	-1.3
Headache pain in last month	0.5	0.8	2.9	-0.9	-0.8	-0.5	-0.3	-0.3	0.4	-0.6	-0.9	-0.9	-1.3	-0.6	-0.5	-1.3	-1.7	-1.1	-0.7
Medication for cholesterol, blood pressure or diabetes	3.7	6.1	9.8	-2.8	-2.8	1.2	-2.1	-3.1	2.5	-3.0	-2.5	-2.8	-1.9	-2.7	-2.0	-2.8	-1.1	-2.6	-2.5
Glaucoma (self-reported)	0.9	1.1	2.9	0.8	0.8	-1.0	1.4	1.7	0.1	1.0	0.4	0.7	-0.0	1.2	1.6	0.6	-1.0	1.5	0.8
Gout (self-reported)	3.6	4.9	11.1	-2.5	-2.5	-0.5	-0.8	-1.0	1.8	-1.9	-2.7	-2.6	-3.1	-2.5	-1.1	-2.3	-3.3	-1.3	-2.6
Hypothyroidism/myxoedema (self-reported)	4.2	8.2	13.0	-3.6	-3.5	2.2	-2.3	-2.5	1.0	-2.0	-1.8	-3.2	-3.2	-3.6	-3.2	-2.8	-2.3	-3.5	-3.5
Medication: Amlodipine	3.0	4.2	9.5	2.1	2.1	-1.8	2.3	3.1	-1.9	2.5	2.0	2.1	1.3	1.9	1.4	1.9	-0.5	2.3	2.1
Medication: Ventolin 100micrograms inhaler	9.3	11.9	17.0	4.0	4.0	-3.2	2.5	3.1	-2.2	4.0	3.1	4.0	3.3	3.9	3.5	4.1	3.0	2.5	4.0
Birth weight	3.4	7.4	15.6	-2.6	-2.5	2.6	-3.3	-3.9	2.1	-3.4	-3.1	-2.7	-2.0	-2.6	-2.6	-2.9	-0.8	-2.2	-3.0
Chronic bronchitis/emphysema (mother)	1.3	1.5	4.1	1.2	1.1	-1.2	2.0	1.8	-1.2	1.1	0.9	1.1	0.7	1.4	0.9	1.5	-0.1	0.8	1.3
High blood pressure (siblings)	4.1	6.0	9.3	2.4	2.4	-2.2	3.0	2.8	-2.7	3.0	2.9	2.7	2.2	2.6	1.6	1.9	0.9	1.8	2.6
Forced vital capacity (FVC), Best measure	1.8	6.8	13.1	-3.1	-3.0	0.8	-1.2	-2.3	1.9	-2.8	-2.8	-3.0	-3.2	-2.9	-1.0	-3.6	-2.7	-2.3	-2.9
Body fat percentage	0.3	1.1	2.5	1.0	1.0	-1.6	1.0	1.2	-0.8	1.4	1.1	1.0	0.6	1.2	1.0	0.1	-0.5	1.5	0.9
Leg fat percentage (right)	2.4	8.9	14.8	3.0	2.9	-3.9	3.3	3.5	-2.3	3.7	3.3	3.0	2.2	3.2	2.9	2.1	0.2	3.2	3.1
Arm fat-free mass (right)	6.7	34.2	63.5	-5.5	-5.3	4.7	-7.3	-8.0	7.1	-7.1	-7.2	-6.0	-4.8	-5.3	-3.5	-6.2	-1.9	-4.6	-6.1
Exposure to tobacco smoke outside home	5.9	7.9	11.3	-3.2	-3.1	1.6	-2.9	-3.4	2.5	-2.7	-2.6	-3.1	-2.7	-3.3	-2.5	-3.0	-1.5	-2.9	-3.2
Comparative body size at age 10	2.0	5.5	11.3	2.1	2.1	-3.4	2.7	2.6	-2.0	3.0	3.1	2.3	1.8	2.4	1.6	2.4	0.5	1.5	2.4
Number of full brothers	0.8	1.1	3.8	-0.6	-0.6	1.9	-1.8	-1.6	0.2	-0.4	-0.4	-0.5	0.0	-1.1	-1.6	-1.0	0.4	-0.6	-0.8
Worry too long after embarrassment	0.3	0.4	2.5	0.0	0.1	-1.6	-0.2	-0.5	0.7	0.1	0.3	0.1	-0.1	-0.0	0.2	0.6	1.0	-1.3	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.9	1.2	4.1	-0.7	-0.6	0.8	-2.0	-1.9	0.6	-0.9	-0.5	-0.6	-0.3	-0.8	-1.8	-1.1	0.8	-1.3	-1.1
Wheeze or whistling in the chest in last year	2.3	4.1	10.6	1.9	1.8	-2.6	2.7	3.3	-0.7	3.1	1.4	1.8	0.5	1.8	2.0	2.3	-0.6	1.9	1.8
Number of children fathered	0.4	0.4	1.8	-0.4	-0.3	0.8	-0.8	-1.4	-0.2	-0.3	0.2	-0.2	0.2	-0.4	-1.1	-0.5	0.8	-1.0	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.4	5.8	1.7	1.7	-0.3	1.5	2.4	-1.2	1.8	1.6	1.8	1.0	1.5	1.1	1.5	-0.1	2.1	1.7
Age at first live birth	0.2	0.4	1.5	0.3	0.3	-0.1	0.8	1.2	-1.1	0.7	0.6	0.4	0.3	0.4	-0.1	0.1	-0.7	1.0	0.5
Pulse wave peak to peak time	0.2	0.2	0.5	-0.4	-0.4	0.4	-0.6	-0.1	0.6	-0.7	-0.7	-0.5	-0.7	-0.5	0.6	0.1	-0.4	-0.1	-0.4
Health satisfaction	2.4	3.2	6.2	2.2	2.2	-0.3	0.6	0.9	-0.7	1.3	1.4	2.1	2.3	2.1	1.6	2.5	2.5	1.7	1.9
Shortness of breath walking on level ground	2.1	2.5	3.5	1.5	1.4	-1.9	1.7	1.6	-1.4	1.9	1.5	1.5	1.5	1.7	1.7	1.7	0.7	1.4	1.6
Qualifications: College or University degree	0.9	2.8	6.4	1.6	1.5	-2.0	2.0	1.6	-1.0	1.4	1.6	1.6	1.5	1.9	2.5	0.9	0.4	1.9	1.9
Eye problems/disorders: None of the above	1.5	1.8	2.6	-1.5	-1.5	0.8	-1.2	-0.9	0.9	-1.4	-1.5	-1.6	-1.6	-1.5	-1.1	-1.1	-1.2	-1.6	-1.5
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.9	0.2	0.2	0.1	-0.9	-0.6	0.5	-0.1	0.3	0.3	0.7	0.1	-0.8	0.2	1.0	-0.4	0.2
Emphysema/chronic bronchitis	0.6	0.6	3.3	-0.3	-0.4	0.1	-0.6	-0.4	1.8	-1.4	-1.8	-0.8	-0.2	-0.4	-0.3	0.1	0.1	0.2	-0.4
Medication for pain relief, constipation, heartburn	0.2	0.3	1.1	0.4	0.4	-0.2	-0.3	-0.7	-0.5	0.5	0.6	0.5	1.0	0.3	0.7	0.0	0.6	0.8	0.5
Neck or shoulder pain in last month	0.4	0.6	2.1	-0.5	-0.5	1.0	0.2	0.0	1.1	-1.1	-1.4	-0.7	-1.1	-0.2	-0.1	-0.6	-0.8	-1.0	-0.5
Medication: Blood pressure	6.2	10.9	14.7	3.8	3.8	-2.2	3.0	3.8	-2.7	3.5	3.1	3.8	2.8	3.7	3.0	3.8	1.7	3.6	3.5
Angina (self-reported)	2.6	3.4	6.1	2.4	2.3	-1.5	1.2	1.6	-0.4	1.8	1.4	2.1	2.2	2.2	0.7	2.5	2.0	1.9	1.9
Migraine (self-reported)	0.3	0.4	1.6	-0.2	-0.2	-1.1	0.4	0.3	0.0	-0.2	-0.6	-0.3	-1.1	0.1	0.6	-0.8	-1.3	-0.4	-0.1
Medication: Ibuprofen	0.2	0.2	1.3	0.0	0.2	1.1	-0.6	-0.3	0.7	-0.8	-0.4	0.1	-0.1	0.1	0.2	0.0	0.5	-0.3	0.1
Medication: Allopurinol	1.8	2.3	7.5	-1.7	-1.6	-1.0	-0.1	-0.5	1.0	-1.1	-1.9	-1.7	-2.3	-1.6	-0.7	-1.5	-2.7	-0.5	-1.8
Medication: Omeprazole	0.5	0.6	2.1	0.6	0.6	0.4	0.9	1.4	-1.4	1.0	1.0	0.7	0.5	0.4	-0.4	0.6	-0.0	0.3	0.6
Medication: Seretide 50 evohaler	15.3	17.6	23.4	4.3	4.2	-4.5	4.7	4.8	-4.1	4.8	4.1	4.4	3.9	4.3	3.7	4.7	2.3	3.2	4.5
Mean time to correctly identify matches	0.1	0.2	0.9	0.4	0.4	0.9	0.2	0.4	-0.2	0.5	0.6	0.4	-0.0	0.2	-0.1	0.3	-0.2	0.5	0.4
Heart disease (mother)	0.4	0.4	2.4	-0.2	-0.4	-1.5	0.9	0.2	-0.1	0.9	1.0	-0.1	0.6	-0.2	-0.6	0.4	0.6	-0.8	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.1	2.4	5.1	-1.4	-1.5	1.7	-2.3	-1.9	1.9	-2.1	-2.0	-1.6	-0.7	-1.6	-1.1	-0.6	0.7	-1.0	-1.6
Whole body fat mass	0.5	2.2	5.2	-1.3	-1.2	0.5	-2.0	-2.0	1.9	-1.6	-1.8	-1.5	-1.4	-1.1	-0.6	-2.3	-1.2	-0.4	-1.5
Leg fat mass (right)	0.1	0.3	1.2	0.1	0.1	-1.1	-0.4	-0.3	0.8	0.1	-0.2	0.0	-0.3	0.4	0.7	-1.0	-0.9	0.9	-0.0
Arm predicted mass (right)	6.4	32.9	60.8	-5.3	-5.2	4.5	-7.2	-7.8	7.2	-7.1	-7.2	-5.8	-4.7	-5.1	-3.3	-6.0	-1.9	-4.4	-5.9
Pulse rate, automated reading	0.6	1.9	4.1	1.3	1.3	-0.6	1.9	1.8	-2.0	1.5	1.7	1.4	0.9	1.5	0.9	0.9	-0.7	1.5	1.4
Alcohol intake frequency.	0.1	0.3	1.7	0.7	0.7	-0.2	0.1	0.1	0.5	0.3	-0.0	0.6	-0.1	0.7	1.3	0.1	-0.3	0.4	0.6
Comparative height size at age 10	14.1	77.4	134.6	-9.1	-8.9	4.8	-9.1	-11.6	9.5	-10.6	-10.5	-9.6	-7.4	-8.8	-6.8	-9.2	-3.0	-8.2	-9.5
Number of full sisters	1.6	1.9	4.7	-1.1	-1.0	0.5	-1.6	-1.9	2.0	-1.9	-2.2	-1.3	-1.3	-0.9	-0.9	-1.3	-0.9	-0.9	-1.2
Suffer from ‘nerves’	0.8	1.3	2.7	-0.9	-0.9	0.2	-1.1	-1.3	1.6	-1.5	-1.5	-1.1	-1.5	-1.0	-0.4	-1.0	-0.8	-1.2	-1.3
Overall health rating	0.1	0.3	1.4	0.0	-0.0	-0.8	0.2	0.3	-0.9	0.9	0.2	0.0	-0.0	-0.0	-1.2	0.4	0.1	-0.5	0.0
Chest pain or discomfort	0.3	0.4	1.4	0.7	0.7	-1.2	0.5	0.6	-0.4	1.0	0.6	0.7	0.5	0.6	-0.2	0.3	-0.0	0.8	0.6
Had major operations	1.2	1.4	5.7	1.0	0.8	-2.4	1.4	0.9	-0.6	0.6	0.5	0.7	1.5	1.1	1.1	1.0	1.3	1.0	1.2
Age at last live birth	0.1	0.1	0.7	-0.1	-0.1	0.4	0.1	0.1	-0.1	-0.5	-0.4	-0.2	-0.1	0.1	-0.4	-0.4	-0.8	0.7	0.1
Family relationship satisfaction	2.1	2.6	5.7	-1.4	-1.3	1.3	-2.4	-2.1	1.6	-2.0	-2.3	-1.5	-1.4	-1.7	-1.1	-0.8	-0.5	-1.5	-1.7
Leg pain on walking	0.2	0.3	0.7	0.5	0.4	-0.7	0.4	0.1	-0.0	0.5	0.6	0.4	0.8	0.5	0.7	0.2	0.9	0.8	0.4
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	1.0	-0.0	-0.1	-0.2	0.1	-0.1	0.3	-0.2	0.1	-0.1	0.4	0.0	-0.0	0.5	1.0	-0.1	-0.2
Commuting to job workplace: Car/motor vehicle	0.5	0.5	1.6	-0.7	-0.9	-1.2	-0.4	-0.7	1.1	-0.4	-0.6	-0.8	-0.0	-0.9	-0.9	-0.4	0.1	-0.5	-0.7
Illness, injury, bereavement, stress in last 2 years	2.8	3.4	8.0	1.7	1.8	-0.6	2.1	2.8	-2.1	2.8	2.5	1.9	1.2	1.5	1.6	1.4	0.3	1.2	2.0
Medication: Aspirin	2.1	2.7	7.0	1.5	1.4	-1.4	2.2	2.7	-1.4	2.4	2.0	1.5	1.3	1.4	0.7	1.8	0.5	1.4	1.6
Supplements: Vitamin C	1.3	1.5	3.6	-1.4	-1.3	0.1	-0.6	-0.5	-0.3	-0.6	-0.8	-1.3	-1.6	-1.1	-1.5	-1.8	-1.9	-1.6	-1.3
Knee pain experienced in last month	0.3	0.5	1.4	0.7	0.7	-0.2	0.6	1.0	-0.5	0.5	0.5	0.6	0.3	0.7	1.2	0.6	-0.5	1.0	0.8
Hypertension (Self-reported)	7.9	21.9	30.9	4.9	4.8	-4.3	5.5	5.6	-3.9	5.3	4.8	5.0	4.1	5.1	4.3	4.4	1.7	4.7	5.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.7	1.0	0.8	0.2	0.2	1.3	-1.0	0.4	0.6	0.8	0.8	0.8	0.3	0.7	0.4	0.3	0.9
Illnesses of father: Heart disease	1.9	2.6	8.5	1.6	1.4	-2.9	2.2	1.8	0.2	0.3	-0.2	1.1	1.1	2.1	2.5	0.9	-0.3	2.1	1.6
Illnesses of siblings: Diabetes	0.7	0.9	3.8	-0.8	-0.7	0.2	0.3	0.7	-1.6	0.9	0.1	-0.5	-1.3	-0.8	-0.9	-1.0	-2.0	-0.8	-0.6
Smoking status: Previous	1.2	1.9	3.7	1.3	1.4	-0.9	1.6	1.4	-1.2	1.4	1.6	1.4	0.6	1.4	1.9	1.5	-0.2	1.6	1.4
Forced expiratory volume in 1-second (FEV1), predicted	10.3	21.5	33.6	-4.7	-4.6	3.0	-4.6	-5.8	4.6	-5.7	-5.8	-5.0	-4.6	-4.7	-2.8	-5.1	-2.2	-4.1	-5.1
Whole body fat-free mass	8.0	45.8	87.6	-6.4	-6.2	5.4	-8.4	-9.4	8.1	-8.2	-8.1	-6.9	-5.5	-6.2	-4.2	-7.2	-2.2	-5.3	-7.0
Leg fat-free mass (right)	7.6	40.6	78.0	-5.9	-5.7	5.6	-8.1	-8.8	7.4	-7.7	-7.6	-6.3	-5.1	-5.8	-4.2	-6.8	-2.0	-5.0	-6.6
Arm fat percentage (left)	0.6	2.2	4.2	1.6	1.6	-1.6	1.1	1.5	-1.3	2.0	1.8	1.6	1.2	1.8	1.4	0.5	0.1	1.9	1.5
Average weekly red wine intake	0.5	0.7	3.6	-0.2	-0.2	-1.0	0.9	1.1	-1.9	1.1	1.4	0.1	-0.1	-0.1	0.5	0.1	-0.4	-0.3	0.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.8	-0.2	-0.2	-0.2	0.3	0.1	-0.2	0.9	0.8	0.1	0.0	-0.3	-0.7	0.3	0.8	-0.7	0.0
Mood swings	0.1	0.2	1.6	-0.4	-0.3	-0.6	-0.3	-0.2	0.0	0.6	0.4	-0.2	-0.1	-0.5	-0.7	0.3	0.3	-1.3	-0.4
Loneliness, isolation	0.1	0.1	0.7	-0.3	-0.2	-0.3	-0.4	-0.3	0.4	-0.2	-0.2	-0.3	-0.5	-0.3	-0.3	0.0	-0.1	-0.8	-0.3
Long-standing illness, disability or infirmity	3.1	4.7	6.9	2.3	2.4	-1.4	2.1	2.3	-2.6	2.5	2.3	2.4	2.3	2.2	1.0	2.1	1.4	2.2	2.4
Ever had bowel cancer screening	0.4	0.5	2.5	-0.3	-0.4	1.6	-0.9	-0.8	0.6	-0.9	-0.6	-0.5	-0.0	-0.4	-1.2	-0.2	0.2	-0.4	-0.4
Diabetes diagnosed by doctor	0.5	0.9	2.8	1.1	1.2	-1.7	0.8	1.0	-0.3	0.6	0.2	1.0	0.5	1.1	0.6	0.6	-0.3	1.6	0.9
Ever had stillbirth, spontaneous miscarriage or termination	2.1	2.2	5.5	2.1	2.1	-0.6	0.4	0.5	-0.9	0.9	1.1	1.9	2.0	2.0	0.6	1.0	1.0	2.4	1.8
Friendships satisfaction	0.3	0.4	1.6	0.1	0.1	1.1	-0.9	-0.6	1.2	-1.3	-0.9	-0.1	-0.0	-0.1	-0.0	0.2	0.2	-0.5	-0.1
Qualifications: nursing, teaching	0.8	1.2	4.8	0.7	0.7	-2.2	1.2	0.3	0.8	-0.7	-0.8	0.4	-0.3	1.2	2.1	-0.4	-1.2	1.2	0.6
Commuting to job workplace: Walk	0.3	0.3	1.4	0.6	0.6	0.7	0.3	0.4	-0.3	0.3	0.6	0.6	0.0	0.8	1.2	0.6	0.7	-0.1	0.5
Eye problems/disorders: Cataract	0.2	0.3	1.1	0.0	0.0	-0.4	0.4	-0.1	-1.1	0.8	1.0	0.3	0.6	-0.0	-0.1	-0.1	0.9	-0.2	0.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.0	1.9	-1.2	-1.2	0.8	-1.3	-0.3	0.2	-0.6	-1.1	-1.3	-1.1	-1.3	-1.4	-0.8	-0.9	-1.0	-1.0
Medication for cholesterol	3.9	6.0	10.8	-2.5	-2.4	2.2	-2.4	-2.9	2.5	-3.3	-2.9	-2.6	-2.4	-2.4	-1.4	-2.4	-1.3	-2.1	-2.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.7	4.4	8.0	-2.5	-2.4	1.1	-0.8	-1.6	1.8	-1.7	-1.8	-2.3	-2.6	-2.4	-2.8	-2.0	-1.4	-2.6	-2.4
Back pain experienced in last month	2.3	3.4	6.8	-2.0	-2.0	2.1	-2.3	-2.2	0.0	-1.1	-1.2	-1.9	-0.9	-2.1	-2.6	-1.8	0.6	-2.5	-1.9
Mineral and other dietary supplements	0.4	0.5	3.2	0.6	0.5	0.5	-0.4	-0.1	0.5	0.6	0.6	0.6	0.9	0.3	0.1	1.1	1.8	0.1	0.5
Breast cancer (self-reported)	3.6	4.3	6.9	-2.2	-2.1	1.6	-2.0	-2.6	1.6	-2.5	-2.3	-2.3	-2.1	-2.1	-1.5	-2.3	-1.3	-1.8	-2.4
Asthma (self-reported)	26.5	52.7	85.2	7.5	7.5	-8.1	8.5	8.9	-5.6	9.2	6.9	7.6	5.1	7.6	6.5	8.2	2.3	5.9	7.7
Osteoporosis (self-reported)	0.4	0.5	1.7	-0.7	-0.6	-0.1	-0.6	-0.7	1.2	-0.7	-0.7	-0.6	-0.9	-0.7	-0.5	-0.0	0.0	-1.3	-0.5
Osteoarthritis (self-reported)	5.4	7.0	14.4	2.7	2.7	-0.4	2.0	2.8	-3.6	3.5	3.8	3.0	2.7	2.5	1.4	2.2	1.8	1.9	3.1
Medication: Aspirin	1.7	2.3	5.3	1.3	1.2	-1.6	2.1	2.1	-1.3	2.3	1.9	1.3	1.2	1.3	0.5	1.6	0.7	1.1	1.4
Medication: Gliclazide	0.1	0.1	0.5	0.3	0.4	-0.3	-0.2	-0.2	-0.1	-0.5	0.0	0.3	0.6	0.3	-0.4	-0.1	0.7	0.5	0.2
Illnesses of father: None of the above (group 1)	1.4	1.8	3.7	-1.3	-1.3	1.9	-1.5	-1.7	0.8	-0.9	-0.6	-1.2	-1.4	-1.5	-1.5	-1.3	-0.4	-1.6	-1.4
Smoking status: Current	0.3	0.5	1.7	-0.3	-0.3	-0.2	-1.2	-1.3	0.8	-0.7	-0.8	-0.4	0.2	-0.3	-1.3	-0.6	0.8	-0.3	-0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.4	-1.5	-1.6	0.5	-0.3	-0.3	-0.2	-0.2	0.3	-1.2	-1.4	-1.5	-1.0	-0.9	-1.0	-1.2	-1.1
Whole body water mass	8.1	46.4	88.9	-6.4	-6.2	5.4	-8.5	-9.4	8.2	-8.3	-8.2	-6.9	-5.5	-6.2	-4.2	-7.2	-2.1	-5.3	-7.1
Leg predicted mass (right)	7.6	40.6	78.1	-5.9	-5.7	5.5	-8.1	-8.8	7.4	-7.7	-7.6	-6.3	-5.1	-5.8	-4.1	-6.8	-2.0	-4.9	-6.6
Arm fat mass (left)	0.2	0.7	2.3	-0.3	-0.3	0.3	-1.5	-1.4	1.5	-0.8	-0.9	-0.5	-0.4	-0.1	0.1	-1.5	-0.4	0.2	-0.6
Number of self-reported non-cancer illnesses	8.1	14.0	20.5	3.9	3.9	-4.3	4.1	4.4	-2.7	4.5	3.4	3.9	3.0	3.9	3.2	4.5	1.8	3.3	3.9
Average weekly champagne plus white wine intake	0.2	0.3	1.6	0.5	0.5	0.4	-0.7	-0.1	0.3	0.1	-0.1	0.4	0.7	0.3	-0.1	0.7	1.3	0.1	0.3
Miserableness	0.6	1.0	2.7	-1.0	-1.0	0.8	-1.5	-1.1	1.1	-0.4	-0.5	-0.9	-0.6	-1.3	-1.1	0.2	0.9	-1.6	-1.1
Guilty feelings	0.6	1.0	5.0	1.0	1.1	-0.3	-1.1	-0.6	0.6	0.6	0.8	1.0	1.2	0.8	0.6	1.1	2.2	-0.3	0.7
Wears glasses or contact lenses	0.2	0.3	1.0	0.2	0.2	-0.2	1.0	0.7	-1.0	0.7	0.8	0.3	-0.2	0.4	-0.0	-0.4	-0.5	0.4	0.1
Ever taken oral contraceptive pill	1.6	1.8	2.5	1.3	1.3	-0.9	1.4	1.5	-1.4	1.2	1.3	1.3	1.6	1.3	1.4	1.4	1.3	1.2	1.3
Hearing aid user	0.9	1.0	2.6	1.1	0.9	-0.2	0.8	0.7	-1.6	1.4	1.4	1.1	1.1	1.0	0.3	1.2	1.0	0.2	1.1
Mother’s age at death	0.2	0.2	0.6	-0.5	-0.5	0.5	-0.6	-0.1	-0.5	0.0	0.2	-0.4	-0.5	-0.5	-0.5	-0.5	-0.8	0.0	-0.5
Financial situation satisfaction	0.2	0.3	0.5	0.7	0.7	-0.7	0.1	0.3	0.5	0.3	-0.1	0.5	0.5	0.6	0.7	0.7	0.4	0.5	0.4
Tinnitus: Yes, now most or all of the time	2.1	2.4	4.1	1.8	1.6	-1.2	1.1	1.6	-1.1	1.3	1.3	1.6	2.0	1.7	1.7	1.5	1.6	1.4	2.0
Commuting to job workplace: Public transport	0.7	0.8	3.0	-0.5	-0.4	1.6	-0.8	-0.8	1.0	-1.7	-1.6	-0.7	-0.9	-0.2	-0.1	-0.5	-0.5	-0.3	-0.7
Eye problems/disorders: Glaucoma	1.6	1.9	3.8	1.3	1.3	-1.0	1.5	1.9	-0.9	1.9	1.5	1.3	0.8	1.5	1.7	1.0	-0.2	1.8	1.3
Medication: Blood pressure	7.4	14.2	26.9	3.2	3.1	-4.6	5.2	5.2	-3.9	5.1	4.5	3.5	2.7	3.4	2.5	3.0	0.2	3.2	3.9
Pain type(s) experienced in last month: Hip pain	2.0	2.5	4.6	-1.5	-1.5	1.2	-1.5	-1.3	2.1	-1.9	-2.1	-1.8	-1.4	-1.3	-1.2	-1.9	-1.3	-1.2	-1.5
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.7	0.1	0.1	-0.5	0.7	0.3	-0.8	-0.3	-0.2	-0.0	0.1	0.4	0.3	-0.5	-0.8	0.6	0.1
High cholesterol (Self-reported)	0.3	0.5	1.2	-0.6	-0.7	-0.1	-0.9	-0.6	1.1	-0.9	-0.8	-0.8	-0.9	-0.7	-0.0	-0.0	0.0	-0.8	-1.0
Medication: Bendroflumethiazide	11.2	17.0	30.6	4.1	4.0	-3.0	4.3	4.8	-4.5	5.5	5.3	4.4	3.5	4.0	3.3	4.0	1.8	3.8	4.3
Medication: Paracetamol	0.4	0.6	1.9	-0.5	-0.6	-0.3	-0.7	-0.6	1.4	-1.2	-1.1	-0.7	-1.0	-0.5	-0.0	-0.5	-0.3	-1.0	-0.5
Medication: Lisinopril	0.2	0.2	1.5	-0.1	0.0	0.2	0.5	1.2	-0.8	0.2	0.1	-0.0	-0.1	-0.3	-0.2	0.2	-0.4	0.8	-0.0
Medication: Atorvastatin	0.4	0.5	1.5	0.8	0.8	-0.2	1.0	1.1	-0.4	0.1	0.2	0.6	0.3	1.0	1.2	0.7	-0.3	0.8	0.9
Illnesses of father: High blood pressure	1.0	1.3	2.3	1.1	1.3	-0.6	1.5	1.5	-0.9	0.6	0.9	1.2	1.2	1.4	0.7	1.4	0.6	1.0	1.4
Alcohol drinker status: Never	0.3	0.4	1.2	0.8	0.6	-1.1	0.6	0.3	0.6	0.0	-0.4	0.4	0.7	0.7	0.4	0.5	0.7	0.1	0.8
Ever smoked	0.4	0.8	1.3	1.0	1.1	-0.4	0.6	0.5	-0.7	0.7	1.0	1.1	0.8	1.0	1.0	1.1	0.7	1.1	0.8
Basal metabolic rate	7.3	40.6	76.6	-6.0	-5.8	4.9	-7.9	-8.8	7.7	-7.8	-7.7	-6.5	-5.3	-5.8	-3.9	-6.9	-2.2	-4.8	-6.6
Leg fat percentage (left)	3.5	12.6	18.1	3.7	3.6	-3.8	3.6	4.0	-2.7	4.3	4.0	3.8	3.0	4.0	3.5	2.9	0.9	3.7	3.9
Arm fat-free mass (left)	6.0	30.6	61.6	-4.9	-4.8	4.3	-7.2	-7.8	7.2	-7.0	-7.0	-5.5	-4.3	-4.7	-3.1	-5.9	-1.6	-3.9	-5.5
Number of operations (self-reported)	0.6	0.9	2.7	-0.6	-0.6	0.4	-1.2	-1.4	1.6	-1.4	-1.4	-0.9	0.0	-0.5	-0.8	-0.6	0.4	-0.5	-0.6
Average weekly beer plus cider intake	2.4	3.5	7.0	-1.5	-1.3	1.4	-2.6	-2.6	2.1	-2.5	-2.4	-1.7	-0.7	-1.5	-2.4	-1.6	0.1	-1.3	-1.7
Irritability	0.2	0.3	0.9	0.3	0.4	0.6	-0.4	0.4	-0.3	0.8	0.6	0.4	0.6	-0.0	-0.2	0.6	0.9	-0.8	0.3
Risk taking	0.3	0.5	2.2	0.7	0.9	-1.5	-0.2	-0.4	0.8	0.3	-0.1	0.6	0.3	0.9	0.3	0.0	-0.3	1.3	0.5
Ever had prostate specific antigen (PSA) test	0.3	0.3	0.9	0.4	0.4	-0.6	0.6	0.7	-0.4	1.0	0.9	0.5	0.3	0.3	0.5	0.9	-0.1	0.5	0.5
Fractured/broken bones in last 5 years	1.1	1.5	4.7	-0.6	-0.6	0.7	-1.6	-2.2	2.0	-2.0	-1.8	-0.9	-0.2	-0.6	-0.9	-0.8	0.4	-0.5	-0.9
Age started oral contraceptive pill	0.2	0.3	0.8	0.6	0.6	0.4	0.1	-0.3	0.9	-0.9	-0.4	0.4	0.8	0.6	0.1	0.1	0.3	0.8	0.6
Diastolic blood pressure, automated reading	3.8	11.8	20.2	3.4	3.2	-2.5	4.5	4.2	-3.7	4.2	4.2	3.5	3.1	3.6	3.0	2.7	1.5	2.5	3.8
Ever depressed for a whole week	0.2	0.2	1.1	-0.1	-0.1	-1.0	0.2	0.1	0.3	-0.3	-0.6	-0.2	-0.6	-0.0	0.4	-0.2	-1.0	0.4	-0.3
Unable to work because of sickness or disability	0.7	1.0	2.3	1.2	1.3	-1.5	0.6	0.3	0.1	0.6	0.2	1.0	1.3	1.3	0.5	0.7	0.7	1.5	1.2
Commuting to job workplace: Cycle	1.9	2.3	5.3	-1.4	-1.4	1.2	-0.7	-1.5	2.0	-2.3	-2.2	-1.7	-1.4	-1.1	-1.0	-1.8	-1.2	-1.1	-1.4
Myopia	0.3	0.4	1.4	-0.4	-0.4	0.3	-0.1	0.2	0.9	-0.8	-0.9	-0.6	-0.9	-0.3	0.1	-0.6	-1.2	-0.0	-0.6
Vascular/heart problems diagnosed by doctor	7.6	20.8	35.2	-4.6	-4.5	4.2	-5.7	-5.9	4.0	-5.7	-4.8	-4.7	-3.6	-4.7	-4.0	-4.2	-1.1	-4.4	-4.8
Cholesterol lowering medication	0.2	0.2	1.4	-0.1	-0.3	-0.5	-0.4	-0.3	1.2	-0.6	-0.5	-0.3	0.1	-0.3	-0.3	0.5	0.6	-0.5	-0.2
Medication: Omeprazole (e.g. Zanprol)	2.0	2.4	7.3	1.4	1.3	-0.6	2.0	2.7	-2.0	2.2	1.9	1.5	1.1	1.3	0.3	1.5	-0.1	1.2	1.6
Pain experienced in last month	0.1	0.1	0.4	-0.2	-0.4	-0.1	0.0	-0.6	0.1	-0.5	-0.2	-0.3	-0.0	-0.4	-0.2	-0.3	-0.0	0.1	-0.4
Supplements: Calcium	2.5	2.8	8.0	-1.5	-1.4	-0.5	-0.9	-1.3	1.6	-2.2	-2.8	-1.9	-1.9	-1.3	-1.0	-1.8	-2.5	-0.7	-1.5
Basal cell carcinoma (self-reported)	1.1	1.3	4.5	-0.9	-0.8	0.5	-2.1	-1.8	1.2	-0.8	-1.2	-0.9	-0.3	-1.2	-1.3	-0.6	1.1	-1.4	-1.0
Heart attack/myocardial infarction (self-reported)	2.4	3.0	5.5	2.3	2.2	-0.7	1.4	2.1	-0.9	1.4	1.1	2.0	1.6	2.2	1.6	2.1	0.5	2.3	2.0
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.5	-0.3	-0.2	0.7	-1.1	-1.2	0.6	-1.1	-1.1	-0.4	-0.0	-0.3	-0.5	-0.8	0.1	0.2	-0.6
Heart disease (siblings)	0.1	0.2	1.2	-0.1	-0.0	-1.1	-0.1	-0.2	0.3	0.1	0.0	-0.0	0.4	0.1	-0.6	-0.0	0.8	-0.6	-0.2
Alcohol drinker status: Previous	0.9	1.0	4.3	0.7	0.8	1.1	-1.6	-1.6	0.8	-0.5	-0.3	0.6	1.2	0.5	0.0	0.4	2.1	0.4	0.5
Pack years of smoking	0.5	0.7	3.6	0.0	0.0	0.0	-1.3	-1.2	1.9	-0.9	-1.2	-0.3	0.4	-0.0	-1.2	0.2	1.0	-0.5	-0.1
Impedance of whole body	0.2	1.0	1.6	-1.2	-1.2	-0.5	1.2	0.4	-1.1	-0.8	-0.7	-1.1	-1.0	-1.2	-1.3	-0.6	-1.3	-1.1	-1.0
Leg fat mass (left)	0.1	0.4	1.3	0.5	0.5	-0.9	-0.2	-0.1	0.7	0.2	0.1	0.4	0.1	0.8	1.1	-0.6	-0.5	1.1	0.4
Arm predicted mass (left)	6.6	33.6	65.3	-5.3	-5.1	4.7	-7.5	-8.1	7.2	-7.1	-7.2	-5.8	-4.6	-5.1	-3.5	-6.2	-1.7	-4.4	-5.8