Best TWAS P=3.46e-08 · Best GWAS P=3.24e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Putamen basal ganglia | DARS2 | 0.13 | 0.01 | enet | 14 | 0.00 | 0.36700 | -5.8 | 5.3 | 1.1e-07 | -0.94 | 0.02 | 0.88 | FALSE |
| 2 | The Cancer Genome Atlas | Esophageal Carcinoma | MRPS14 | 0.12 | -0.01 | blup | 38 | 0.00 | 0.36000 | 4.8 | -5.2 | 2.1e-07 | 0.78 | 0.00 | 0.23 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | MRPS14 | 0.06 | 0.01 | blup | 38 | 0.02 | 0.00091 | -3.4 | -5.3 | 1.0e-07 | 0.83 | 0.00 | 0.67 | FALSE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | RABGAP1L | 0.12 | 0.03 | blup | 305 | 0.03 | 0.01160 | -5.7 | -5.5 | 3.5e-08 | 0.96 | 0.03 | 0.88 | TRUE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | RABGAP1L | 0.12 | 0.01 | lasso | 6 | 0.03 | 0.00050 | -5.8 | -5.5 | 4.1e-08 | 0.88 | 0.06 | 0.94 | FALSE |