Best TWAS P=5.07e-08 · Best GWAS P=1.31e-07 conditioned to 0.118
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | SDCCAG8 | 0.23 | 0.25 | enet | 13 | 0.28 | 3.5e-21 | 5.0 | 5.2 | 1.6e-07 | 0.90 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Whole Blood | SDCCAG8 | 0.18 | 0.15 | lasso | 7 | 0.14 | 6.2e-13 | 4.9 | 5.3 | 1.1e-07 | 0.97 | 0.02 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | SDCCAG8 | 0.09 | 0.04 | blup | 114 | 0.08 | 4.6e-07 | 5.0 | 5.4 | 6.2e-08 | 0.70 | 0.02 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | CEP170 | 0.03 | 0.03 | enet | 4 | 0.02 | 7.9e-04 | 4.9 | 5.1 | 2.9e-07 | 0.90 | 0.02 | 0.93 | FALSE |
| 5 | The Cancer Genome Atlas | Rectum Adenocarcinoma | SDCCAG8 | 0.30 | 0.06 | blup | 113 | 0.12 | 8.0e-04 | 5.1 | 5.5 | 5.1e-08 | 0.79 | 0.02 | 0.87 | TRUE |