Best TWAS P=1.58e-157 · Best GWAS P=1.99e-161 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 6.1e-04 | -26.4 | 26.7 | 1.6e-157 | -0.97 | 0.02 | 0.96 | TRUE |
2 | GTEx | Colon Transverse | GPR126 | 0.13 | -0.01 | lasso | 7 | 0.00 | 4.2e-01 | -9.4 | -8.2 | 2.2e-16 | 0.32 | 0.07 | 0.37 | FALSE |
3 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 1.9e-04 | -12.9 | 21.1 | 2.1e-98 | -0.74 | 0.13 | 0.86 | TRUE |
4 | NTR | Blood | HIVEP2 | 0.02 | 0.01 | blup | 424 | 0.01 | 2.6e-03 | -11.4 | -16.1 | 5.1e-58 | 0.40 | 0.34 | 0.05 | TRUE |
5 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | GPR126 | 0.06 | 0.00 | blup | 69 | 0.01 | 4.6e-02 | -2.2 | -9.9 | 4.0e-23 | 0.42 | 0.02 | 0.07 | FALSE |
6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NMBR | 0.03 | 0.03 | blup | 46 | 0.02 | 3.6e-05 | 6.7 | -8.0 | 1.7e-15 | 0.13 | 0.84 | 0.08 | TRUE |
7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NMBR | 0.04 | 0.04 | enet | 9 | 0.03 | 1.7e-04 | 5.9 | -5.7 | 1.1e-08 | 0.11 | 0.37 | 0.07 | FALSE |
8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | VTA1 | 0.03 | 0.02 | blup | 66 | 0.02 | 1.7e-03 | 8.2 | -7.4 | 1.6e-13 | 0.08 | 0.24 | 0.02 | TRUE |
9 | The Cancer Genome Atlas | Thyroid Carcinoma | VTA1 | 0.03 | 0.04 | enet | 3 | 0.01 | 1.2e-02 | 6.0 | -5.6 | 1.8e-08 | 0.07 | 0.20 | 0.02 | FALSE |
10 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NMBR | 0.09 | 0.01 | blup | 46 | 0.04 | 3.4e-02 | 6.6 | -8.7 | 4.9e-18 | 0.11 | 0.01 | 0.67 | TRUE |