[Hub]/) : Traits : Sitting height :

chr6:141,924,760-143,855,272

Best TWAS P=1.58e-157 · Best GWAS P=1.99e-161 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous GPR126 0.06 0.04 lasso 4 0.04 6.1e-04 -26.4 26.7 1.6e-157 -0.97 0.02 0.96 TRUE
2 GTEx Colon Transverse GPR126 0.13 -0.01 lasso 7 0.00 4.2e-01 -9.4 -8.2 2.2e-16 0.32 0.07 0.37 FALSE
3 METSIM Adipose GPR126 0.05 0.01 blup 429 0.02 1.9e-04 -12.9 21.1 2.1e-98 -0.74 0.13 0.86 TRUE
4 NTR Blood HIVEP2 0.02 0.01 blup 424 0.01 2.6e-03 -11.4 -16.1 5.1e-58 0.40 0.34 0.05 TRUE
5 The Cancer Genome Atlas Bladder Urothelial Carcinoma GPR126 0.06 0.00 blup 69 0.01 4.6e-02 -2.2 -9.9 4.0e-23 0.42 0.02 0.07 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma NMBR 0.03 0.03 blup 46 0.02 3.6e-05 6.7 -8.0 1.7e-15 0.13 0.84 0.08 TRUE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NMBR 0.04 0.04 enet 9 0.03 1.7e-04 5.9 -5.7 1.1e-08 0.11 0.37 0.07 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma VTA1 0.03 0.02 blup 66 0.02 1.7e-03 8.2 -7.4 1.6e-13 0.08 0.24 0.02 TRUE
9 The Cancer Genome Atlas Thyroid Carcinoma VTA1 0.03 0.04 enet 3 0.01 1.2e-02 6.0 -5.6 1.8e-08 0.07 0.20 0.02 FALSE
10 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma NMBR 0.09 0.01 blup 46 0.04 3.4e-02 6.6 -8.7 4.9e-18 0.11 0.01 0.67 TRUE