Best TWAS P=1.58e-14 · Best GWAS P=3.99e-16 conditioned to 1.66e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TULP4 | 0.16 | 0.08 | bslmm | 596 | 0.12 | 2.9e-14 | -6.0 | -5.8 | 5.1e-09 | -0.45 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Artery Aorta | SNX9 | 0.14 | 0.00 | lasso | 3 | 0.00 | 1.9e-01 | 8.1 | 5.6 | 2.3e-08 | 0.61 | 0.01 | 0.97 | FALSE |
| 3 | GTEx | Thyroid | TULP4 | 0.09 | 0.02 | lasso | 4 | 0.03 | 1.4e-03 | 8.1 | 5.7 | 1.0e-08 | 0.51 | 0.04 | 0.79 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | TULP4 | 0.07 | 0.02 | lasso | 3 | 0.03 | 1.2e-04 | 8.1 | -5.3 | 9.8e-08 | -0.59 | 0.02 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TULP4 | 0.09 | 0.05 | blup | 148 | 0.04 | 2.0e-05 | 5.4 | -7.7 | 1.6e-14 | -0.53 | 0.73 | 0.06 | TRUE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | TULP4 | 0.03 | 0.03 | lasso | 3 | 0.02 | 5.1e-03 | 4.9 | -5.2 | 2.6e-07 | -0.61 | 0.11 | 0.53 | FALSE |