Best TWAS P=1.25e-16 · Best GWAS P=5.8e-22 conditioned to 3.05e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RPS6KA2 | 0.08 | 0.02 | lasso | 4 | 0.02 | 4.1e-03 | 8.9 | -8.3 | 1.3e-16 | 0.77 | 0.08 | 0.39 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | LINC00473 | 0.08 | 0.02 | bslmm | 700 | 0.02 | 7.9e-04 | -9.6 | 6.6 | 4.5e-11 | -0.67 | 0.00 | 0.99 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | SDIM1 | 0.08 | 0.03 | enet | 15 | 0.04 | 1.9e-05 | -6.5 | 6.1 | 1.2e-09 | -0.42 | 0.53 | 0.42 | FALSE |