Best TWAS P=8.76e-14 · Best GWAS P=6.24e-24 conditioned to 1.17e-26
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | SMOC2 | 0.24 | 0.05 | lasso | 6 | 0.05 | 1.7e-04 | 6.4 | -6.2 | 4.5e-10 | -0.10 | 0.87 | 0.01 | FALSE |
| 2 | GTEx | Nerve Tibial | AL391319.1 | 0.20 | 0.04 | lasso | 4 | 0.05 | 9.5e-05 | 5.9 | -6.2 | 4.5e-10 | -0.09 | 0.80 | 0.01 | TRUE |
| 3 | GTEx | Thyroid | AL391319.1 | 0.15 | 0.12 | lasso | 4 | 0.11 | 1.0e-08 | -7.3 | 7.5 | 8.8e-14 | 0.03 | 1.00 | 0.00 | TRUE |