Best TWAS P=2.35e-08 · Best GWAS P=2.22e-08 conditioned to 0.142
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | RP11-611L7.1 | 0.19 | 0.18 | enet | 17 | 0.15 | 3.9e-19 | 4.9 | 5.6 | 2.3e-08 | 0.88 | 0.07 | 0.93 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | ZNF12 | 0.07 | 0.02 | blup | 32 | 0.05 | 2.8e-05 | 4.9 | 5.2 | 2.5e-07 | 0.79 | 0.01 | 0.95 | FALSE |