TWAS hub - DBNL

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.212	0.0600	7.4e-09	0.096	0.083	0.124	0.131	0.140	9.3e-12	2.4e-10	7.5e-15	1.3e-15	1.1e-16
2	GTEx	Cells Transformed fibroblasts	0.147	0.0520	1.1e-03	0.064	NA	0.076	NA	0.066	1.5e-05	NA	2.5e-06	NA	1.2e-05
3	GTEx	Esophagus Mucosa	0.127	0.0480	1.6e-04	0.030	NA	0.070	NA	0.069	4.1e-03	NA	2.1e-05	NA	2.3e-05
4	GTEx	Esophagus Muscularis	0.356	0.0760	2.7e-06	0.185	NA	0.122	NA	0.168	2.1e-11	NA	7.5e-08	NA	2.0e-10
5	GTEx	Heart Left Ventricle	0.192	0.0651	1.6e-04	0.068	NA	0.050	NA	0.056	1.8e-04	NA	1.2e-03	NA	5.9e-04
6	GTEx	Skin Not Sun Exposed Suprapubic	0.149	0.0590	1.3e-03	0.001	NA	0.035	NA	0.013	2.9e-01	NA	5.0e-03	NA	6.0e-02
7	GTEx	Testis	0.138	0.0590	5.4e-03	0.131	NA	0.048	NA	0.070	2.0e-06	NA	3.3e-03	NA	4.8e-04
8	GTEx	Thyroid	0.128	0.0570	3.0e-03	0.095	NA	0.070	NA	0.075	1.0e-07	NA	4.9e-06	NA	2.3e-06
9	ROSMAP	Brain Pre-frontal Cortex	0.410	0.0537	0.0e+00	0.226	0.233	0.301	0.282	0.317	1.6e-28	1.4e-29	3.5e-39	2.3e-36	1.5e-41
10	YFS	Blood	0.187	0.0303	0.0e+00	0.076	0.138	0.147	0.138	0.148	8.8e-24	9.9e-43	7.2e-46	1.1e-42	4.4e-46
11	TCGA	Bladder Urothelial Carcinoma	0.191	0.0850	3.1e-03	0.070	0.024	0.050	NA	0.060	1.6e-06	3.7e-03	4.5e-05	NA	8.6e-06
12	TCGA	Breast Invasive Carcinoma	0.174	0.0598	1.9e-08	0.056	0.045	0.053	NA	0.055	1.6e-11	1.4e-09	5.2e-11	NA	2.0e-11
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.226	0.0689	9.5e-08	0.068	0.089	0.100	NA	0.087	4.0e-08	3.5e-10	2.6e-11	NA	4.6e-10
14	TCGA	Brain Lower Grade Glioma	0.390	0.0937	9.9e-13	0.123	0.145	0.141	NA	0.146	8.0e-14	3.9e-16	1.1e-15	NA	3.2e-16
15	TCGA	Lung Adenocarcinoma	0.212	0.0682	1.2e-07	0.083	0.084	0.090	NA	0.092	6.5e-10	5.0e-10	1.2e-10	NA	6.6e-11
16	TCGA	Pancreatic Adenocarcinoma	0.402	0.1240	7.1e-03	0.070	0.022	0.057	NA	0.045	6.8e-04	4.1e-02	2.0e-03	NA	5.8e-03
17	TCGA	Prostate Adenocarcinoma	0.303	0.1007	7.3e-10	0.073	0.113	0.112	NA	0.130	4.3e-08	8.2e-12	9.1e-12	NA	1.6e-13
18	TCGA	Soft Tissue Sarcoma	0.144	0.0870	8.1e-03	-0.003	0.013	0.036	NA	0.018	5.1e-01	5.6e-02	3.4e-03	NA	2.9e-02
19	TCGA	Thyroid Carcinoma	0.191	0.0760	2.7e-05	0.032	0.062	0.069	NA	0.077	4.1e-04	1.2e-06	2.7e-07	NA	6.0e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Supplements: Calcium	5.9	6.5	10.1	2.9	1.5	2.3	2.4	2.1	1.1	-0.3	2.4	3.2	2.6	2.7	2.9	2.9	3.0	3.0	2.8	2.5	3.2	2.9
HbA1C	4.4	4.9	8.8	-1.6	-2.7	-2.8	-2.7	-1.7	-0.3	-1.4	-3.0	-2.1	-1.8	-2.8	-2.5	-2.7	-2.4	-2.5	-1.3	-2.7	-1.2	-1.9
Mouth/teeth dental problems: Bleeding gums	4.3	5.6	11.4	-2.9	-0.6	-1.2	-2.4	-2.5	0.1	0.3	-1.9	-3.2	-2.6	-2.6	-2.9	-2.2	-3.0	-2.4	-3.4	-1.4	-2.5	-3.0
Chronotype (morning person)	4.1	9.5	16.8	4.0	1.4	0.5	3.0	2.3	1.1	-1.3	2.5	4.0	3.9	3.3	3.8	3.4	3.9	3.0	3.5	2.7	3.3	4.1
Vitamin and mineral supplements	4.0	5.5	9.7	-3.1	-1.4	-1.8	-1.6	-2.6	-0.1	0.8	-1.8	-2.9	-2.6	-2.3	-2.8	-2.3	-2.9	-2.4	-2.5	-1.8	-3.0	-3.1
Leg pain on walking	3.6	4.6	9.2	-1.5	-2.3	-3.0	-2.6	-1.0	-1.9	-1.0	-2.6	-2.3	-1.6	-2.6	-2.3	-2.2	-2.2	-2.6	-1.8	-2.3	-1.9	-1.7
Hair/balding pattern: Pattern 3	3.4	5.1	9.8	2.2	2.0	1.6	3.1	1.2	2.7	0.7	2.4	2.4	2.9	2.6	2.6	2.1	2.6	2.5	0.9	2.4	1.8	2.4
Fractured/broken bones in last 5 years	3.4	4.4	8.6	1.7	1.9	1.8	2.5	1.4	-0.1	1.2	2.6	2.1	1.8	2.4	2.3	2.5	2.2	2.6	2.9	2.1	2.2	1.8
Mouth/teeth dental problems	3.2	4.9	8.1	2.4	1.1	1.5	2.2	2.2	0.5	0.2	2.1	2.9	2.1	2.5	2.7	2.5	2.7	2.4	2.7	2.1	2.2	2.5
Multivitamins +/- minerals	3.1	4.0	7.1	2.7	1.1	1.2	1.1	2.2	-0.3	-1.0	1.3	2.5	2.4	1.9	2.3	2.3	2.4	2.0	2.0	1.8	2.6	2.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.1	3.6	5.5	-2.1	-1.6	-0.8	-2.1	0.3	-1.2	0.3	-1.9	-2.2	-2.3	-2.0	-2.2	-2.3	-2.2	-2.1	-2.2	-1.7	-2.3	-2.2
Diabetes diagnosed by doctor	2.8	4.6	8.6	-2.3	-2.1	-2.9	-1.9	-2.5	-1.0	-0.0	-1.6	-2.6	-2.9	-1.8	-2.1	-2.3	-2.2	-2.1	-1.0	-2.5	-2.4	-2.3
Average weekly beer plus cider intake	2.8	4.1	7.3	-1.6	-2.2	-1.0	-2.5	-0.1	-0.7	-1.7	-2.5	-2.1	-1.8	-2.4	-2.3	-2.3	-2.2	-2.7	-2.4	-1.9	-2.1	-1.8
Sitting height	2.7	18.8	33.2	-4.3	-3.8	-2.9	-5.8	-2.1	-0.7	-2.4	-5.3	-5.3	-4.3	-5.7	-5.7	-4.0	-5.5	-5.1	-3.2	-3.9	-3.2	-4.9
Commuting to job workplace: Walk	2.7	2.9	7.0	1.2	2.0	2.6	1.9	0.4	-0.9	0.8	2.5	1.3	1.0	2.2	1.9	1.8	1.8	2.2	1.5	1.9	1.2	1.4
Sensitivity / hurt feelings	2.6	4.4	8.0	2.4	2.1	1.3	2.4	2.5	-1.0	0.1	2.1	2.3	2.8	2.3	2.6	2.0	2.6	1.8	1.9	1.5	1.5	2.6
Age started oral contraceptive pill	2.6	3.2	8.2	-2.9	-0.4	-1.6	-0.7	-2.8	0.0	2.3	-0.5	-1.9	-2.5	-0.9	-1.7	-1.8	-1.9	-0.9	-0.9	-1.5	-2.3	-2.6
Alcohol drinker status: Previous	2.6	3.0	5.5	2.3	1.4	0.5	1.6	1.8	0.8	-0.9	1.7	2.0	1.9	1.7	2.1	1.7	2.1	1.8	1.1	1.7	1.9	2.3
Crohns Disease (2012)	2.5	4.1	12.8	-2.4	-3.6	-3.1	-3.2	0.0	-2.8	-1.2	-3.5	-2.5	-2.4	0.0	0.0	-1.4	0.0	0.0	-1.1	-1.5	0.0	0.0
Pack years of smoking	2.4	3.5	6.8	-1.8	-1.1	-0.2	-2.2	-0.4	1.3	-0.2	-1.9	-2.6	-2.1	-2.6	-2.5	-2.1	-2.5	-2.0	-2.3	-1.4	-1.2	-2.1
Waist Hip Ratio (WHR)	2.3	10.4	19.2	2.3	4.0	3.6	4.3	2.2	-0.9	2.0	4.4	2.9	2.6	4.3	3.9	3.2	3.7	3.4	3.7	2.6	1.6	2.9
Diabetes (mother)	2.3	3.0	7.6	-1.2	-1.8	-2.1	-1.2	-0.9	-1.7	-0.5	-1.6	-1.7	-1.0	-1.5	-1.5	-2.6	-1.5	-2.1	-2.0	-2.8	-2.0	-1.2
Pack years adult smoking proportion	2.3	3.5	7.1	-1.6	-1.4	-0.6	-2.3	0.1	1.0	-0.6	-2.2	-2.4	-1.9	-2.7	-2.5	-2.1	-2.4	-2.2	-2.3	-1.6	-1.2	-2.0
Time employed in main current job	2.3	2.6	7.5	-2.6	1.2	1.6	-0.4	-2.1	0.0	2.2	0.3	-2.3	-2.7	-0.8	-1.6	-0.7	-1.9	-0.4	-0.7	-0.1	-1.6	-2.5
Alcohol intake versus 10 years previously	2.3	3.4	11.8	0.0	-3.4	-2.2	-2.8	1.3	-0.8	-2.6	-3.0	-0.9	0.0	-2.4	-1.7	-1.4	-1.3	-2.3	-0.6	-1.8	-0.5	-0.4
Loud music exposure frequency	2.3	2.5	7.3	0.8	2.3	2.7	1.9	0.6	-0.0	1.4	2.0	1.0	0.9	1.7	1.5	1.9	1.4	1.7	1.2	2.0	1.0	1.0
Glaucoma (self-reported)	2.3	2.7	6.7	-1.5	-2.4	-2.6	-1.3	-0.3	-0.8	-0.1	-2.0	-0.8	-0.8	-1.7	-1.7	-2.3	-1.7	-1.7	-1.0	-2.6	-1.3	-1.6
Breast cancer (self-reported)	2.3	2.8	5.3	-1.8	-1.9	-0.7	-1.5	-1.2	-1.0	-0.3	-1.5	-2.0	-2.0	-1.8	-1.9	-2.3	-1.9	-1.6	-0.8	-2.3	-1.4	-1.9
Exposure to tobacco smoke at home	2.2	2.5	5.4	-1.9	-0.1	1.0	-1.0	-2.0	-0.4	1.6	-0.4	-2.0	-2.1	-1.3	-1.6	-2.3	-1.7	-1.0	-2.2	-1.9	-1.2	-1.9
Chronic bronchitis/emphysema (mother)	2.2	2.5	6.5	-1.4	-1.1	-1.5	-2.0	-0.8	-0.2	-0.1	-1.6	-2.1	-1.9	-1.7	-1.7	-1.6	-1.7	-1.7	-2.6	-1.3	-1.3	-1.5
Eye problems/disorders: None of the above	2.2	2.5	4.2	1.9	1.3	2.1	1.4	1.9	-0.6	-1.0	1.2	1.5	1.8	1.6	1.8	1.9	2.0	1.0	1.8	1.5	1.1	2.0
Medication: Ibuprofen	2.2	2.6	5.0	-1.4	-1.8	-1.3	-2.0	0.8	-1.4	-0.1	-1.9	-1.5	-1.0	-1.9	-1.9	-2.0	-1.8	-1.8	-1.6	-2.2	-1.1	-1.6
Diabetes (self-reported)	2.1	3.2	7.8	-1.9	-1.8	-2.5	-1.5	-2.8	-0.8	0.1	-1.2	-2.0	-2.4	-1.4	-1.7	-1.9	-1.8	-1.6	-0.5	-2.1	-1.9	-1.9
Qualifications: A levels/AS levels or equivalent	2.1	4.8	10.7	1.5	3.3	2.2	2.7	-0.0	1.9	1.0	2.7	1.5	1.6	2.5	2.3	2.7	2.1	2.7	1.9	3.0	1.8	1.7
Average weekly champagne plus white wine intake	2.1	2.8	4.7	1.7	1.6	0.8	1.6	0.6	0.5	0.4	1.8	2.0	1.8	1.9	2.0	2.2	2.0	2.1	1.7	1.9	1.8	1.8
Type 2 Diabetes (T2D) (2012)	2.0	2.3	4.7	-2.1	-1.2	-0.3	-1.0	-2.2	-1.7	0.8	-1.1	-1.5	-1.8	-1.3	-1.7	-2.0	-1.7	-1.1	0.2	-2.1	-1.1	-2.0
Tense / ‘highly strung’	2.0	3.4	5.9	1.9	1.7	1.5	1.4	1.9	2.2	-0.4	1.7	1.9	1.8	1.6	1.8	2.2	1.8	2.2	1.4	2.4	2.4	1.8
Ulcerative Colitis (UC)	1.9	3.5	11.8	-1.4	-3.2	-3.4	-1.8	-0.1	-1.6	-0.3	-1.8	-1.3	-1.5	-1.6	-1.6	-2.1	-1.6	-2.1	-1.4	-2.1	-2.1	-1.4
Cardiovascular Disease	1.9	6.2	11.2	2.1	2.4	1.9	3.2	0.2	0.3	1.0	3.2	2.8	2.4	3.4	3.1	2.0	3.0	3.1	3.3	1.6	2.1	2.5
Breast Cancer	1.8	4.2	6.6	2.5	1.6	1.6	1.9	2.0	0.7	-0.9	2.0	2.1	2.0	2.2	2.5	2.5	2.5	1.9	2.2	2.2	2.0	2.6
Type 2 Diabetes (T2D) (2018)	1.8	3.3	7.0	-2.1	-1.8	-2.0	-1.4	-2.6	0.2	0.2	-1.2	-2.4	-2.6	-1.7	-2.0	-1.7	-2.1	-1.7	-1.0	-1.8	-1.9	-2.1
Frequency of depressed mood in last 2 weeks	1.8	2.6	7.0	-2.0	-0.3	0.1	-1.8	-0.3	-0.1	0.5	-1.1	-2.7	-2.4	-1.7	-2.0	-1.0	-2.1	-1.4	-2.4	0.0	-1.5	-2.1
Knee pain experienced in last month	1.8	2.7	8.1	-1.2	-1.7	-0.2	-2.8	0.6	-0.7	-1.2	-2.4	-1.7	-0.9	-2.5	-2.2	-1.1	-2.1	-1.8	-2.0	-0.7	-0.5	-1.6
Fasting Glucose	1.7	2.0	11.8	-1.6	-0.7	-1.0	-0.9	-3.4	-0.3	1.0	-0.4	-1.7	-2.3	-0.7	-1.0	-1.6	-1.2	-0.5	-1.3	-1.0	-1.2	-1.3
HDL Cholesterol	1.7	2.8	5.3	-1.1	-2.1	-1.8	-2.0	-1.1	-0.2	-1.4	-2.3	-1.2	-1.7	-2.0	-1.7	-2.0	-1.5	-2.0	-1.6	-2.1	-1.1	-1.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	3.8	1.1	1.7	1.9	1.9	1.0	1.0	0.5	1.8	1.6	1.4	1.8	1.6	1.2	1.6	2.0	1.3	1.3	1.4	1.2
Depression (Nagel 2018)	1.6	2.4	7.2	-2.1	-0.6	0.0	-1.4	-1.0	-0.6	1.3	-0.7	-2.3	-2.7	-1.4	-1.8	-1.3	-2.0	-1.1	-1.8	-0.5	-1.5	-2.2
Irritable Bowel Disease (IBD)	1.6	3.7	11.7	-1.0	-3.2	-3.4	-1.6	0.5	-2.8	-0.8	-2.0	-0.9	-0.9	-1.5	-1.4	-2.4	-1.3	-2.2	-1.2	-2.6	-2.2	-1.0
Blood Platelet Count	1.6	18.9	30.2	-4.2	-5.0	-4.4	-4.2	-3.8	-2.2	-0.4	-4.7	-4.2	-4.2	-4.8	-4.9	-5.5	-4.9	-4.5	-4.5	-5.1	-3.8	-4.5
Pain all over the body in last month	1.6	1.7	2.7	1.6	1.3	1.0	1.3	1.0	1.2	0.6	1.3	1.0	1.4	1.1	1.4	1.6	1.4	1.4	0.9	1.5	1.6	1.5
Mouth/teeth dental problems: Loose teeth	1.6	1.9	3.2	-1.2	-1.5	-0.9	-1.3	0.4	-1.5	0.6	-1.4	-1.6	-0.9	-1.5	-1.5	-1.8	-1.5	-1.6	-1.8	-1.6	-1.4	-1.3
High cholesterol (Self-reported)	1.6	2.8	6.2	1.1	2.1	1.9	1.9	-0.4	-0.1	0.6	2.5	1.7	0.9	2.4	2.1	1.3	1.9	2.2	2.3	1.0	1.3	1.4
Schizophrenia (2018)	1.5	3.2	5.5	-2.3	-1.8	-1.9	-2.1	-1.1	-0.5	0.3	-2.4	-2.1	-2.3	-1.7	-1.9	-1.6	-2.0	-1.7	-1.2	-1.6	-1.8	-2.0
Ulcerative Colitis	1.5	2.2	10.0	-1.8	-2.8	-3.2	-1.8	-0.5	-2.9	0.1	-1.5	-1.4	-1.9	0.0	0.0	-0.2	0.0	0.0	0.4	-0.3	-0.7	0.0
Systolic Blood Pressure	1.5	7.5	15.1	3.0	1.5	0.8	3.5	1.0	0.4	1.1	3.0	3.9	3.2	3.7	3.7	1.8	3.7	3.2	3.1	1.2	2.3	3.3
Chronic bronchitis/emphysema (father)	1.5	1.8	4.4	-1.2	-0.6	-1.9	-1.5	-2.1	1.6	-0.3	-1.1	-1.3	-1.5	-1.6	-1.6	-0.9	-1.5	-1.2	-1.0	-0.7	-0.5	-1.4
Qualifications: O levels/GCSEs or equivalent	1.5	2.5	3.7	1.4	1.8	1.3	1.9	0.9	1.9	1.1	1.4	1.4	1.9	1.6	1.6	1.8	1.6	1.6	1.3	1.8	1.5	1.4
Medication: Gliclazide	1.5	1.7	3.2	1.0	0.7	-0.6	1.4	-1.2	0.6	0.5	1.6	1.5	0.2	1.8	1.6	1.7	1.5	1.8	1.6	1.5	1.1	1.2
Eye problems/disorders: Glaucoma	1.5	1.8	4.4	-1.7	-1.7	-1.6	-0.8	-0.1	-0.4	0.8	-1.5	-0.6	-0.8	-1.2	-1.5	-1.9	-1.6	-1.0	-0.9	-2.1	-1.1	-1.7
Pain type(s) experienced in last month: Hip pain	1.5	1.8	3.6	-1.7	-0.7	-0.6	-1.6	-1.2	-0.1	0.4	-1.2	-1.7	-1.9	-1.7	-1.9	-1.2	-1.9	-1.0	-1.4	-0.8	-0.8	-1.9
Schizophrenia (2014)	1.4	3.2	6.7	-2.6	-1.4	-1.7	-1.7	-1.6	-0.9	1.0	-2.0	-2.2	-2.3	-1.5	-1.9	-1.6	-2.0	-1.5	-1.4	-1.5	-1.9	-2.2
Hearing difficulty/problems: Yes	1.4	2.1	11.6	1.2	1.9	3.4	0.9	2.5	0.5	-0.2	1.2	0.9	1.6	1.0	1.1	1.2	1.2	1.2	0.2	1.3	1.3	1.2
Father’s age at death	1.4	1.9	7.2	0.5	2.6	2.7	1.2	-0.1	0.1	1.0	1.9	0.3	0.5	1.5	1.2	1.7	1.1	1.2	0.8	1.9	0.3	0.8
Hearing aid user	1.4	1.6	5.2	-1.2	-1.3	0.0	-0.8	0.9	-2.3	0.3	-1.0	-0.8	-1.0	-0.9	-1.0	-1.9	-1.1	-1.4	-1.2	-1.9	-1.7	-1.1
Worry (Nagel 2018)	1.3	2.6	5.3	1.6	1.8	2.3	1.5	2.3	0.8	0.1	1.7	1.3	1.4	1.6	1.7	1.8	1.7	1.8	0.8	2.0	1.7	1.6
Mean Putamen Volume	1.3	1.5	3.6	1.1	1.4	1.5	1.0	0.0	1.9	-0.2	0.9	1.0	1.0	0.8	0.9	1.8	0.9	1.1	1.5	1.8	1.5	0.9
Age when periods started (menarche)	1.3	3.1	5.0	2.2	1.9	1.6	1.1	0.7	1.0	-0.6	1.3	1.9	1.8	1.5	1.9	2.2	2.0	1.8	2.2	2.0	2.2	2.1
Arm predicted mass (right)	1.3	6.4	17.9	-1.4	-2.6	-1.6	-4.2	0.6	1.2	-2.7	-3.8	-2.6	-1.8	-4.0	-3.4	-1.5	-3.0	-3.3	-1.9	-1.6	-0.7	-2.0
Medication: Co-codamol	1.2	1.4	2.7	-1.2	-1.6	-1.5	-1.3	0.2	-0.0	-0.3	-1.6	-1.2	-0.8	-1.6	-1.5	-0.8	-1.5	-1.6	-0.3	-1.0	-1.2	-1.3
Current tobacco smoking	1.2	2.0	4.1	-1.5	-0.7	-1.5	-1.0	-1.0	-0.6	0.1	-1.2	-1.8	-2.0	-1.4	-1.6	-1.5	-1.6	-1.6	-1.9	-1.2	-1.5	-1.5
Number of live births	1.2	1.7	4.8	1.7	1.4	0.9	1.0	2.2	1.7	-0.0	0.9	0.9	1.3	1.1	1.4	1.5	1.4	0.9	0.5	1.6	1.1	1.7
Arm fat-free mass (right)	1.2	6.1	17.0	-1.2	-2.6	-1.7	-4.1	0.8	1.2	-2.9	-3.8	-2.5	-1.6	-3.9	-3.2	-1.4	-2.8	-3.3	-1.8	-1.5	-0.6	-1.9
Alcohol intake frequency.	1.2	2.8	9.5	2.8	-0.4	-0.4	0.7	3.1	-0.6	-1.6	0.4	1.9	2.5	1.0	1.8	1.1	2.0	0.8	1.1	0.8	1.9	2.6
Ever had bowel cancer screening	1.2	1.4	3.2	-1.4	-1.2	-0.9	-1.4	-0.4	-0.5	-0.3	-1.1	-1.6	-1.5	-1.3	-1.4	-0.8	-1.4	-1.5	-1.2	-0.5	-1.8	-1.4
Alzheimer’s Disease (in father)	1.1	1.2	2.5	1.6	0.1	-0.3	0.5	1.0	1.3	-1.6	0.4	0.8	1.1	0.6	1.0	1.4	1.2	0.6	1.3	0.9	1.5	1.5
Lupus	1.1	1.7	2.8	1.3	1.4	1.5	1.7	-0.0	0.2	-0.6	1.4	1.4	1.4	1.4	1.5	1.2	1.5	1.6	0.7	1.2	1.4	1.4
Height	1.1	20.9	36.2	-6.0	-2.6	-2.7	-5.0	-3.5	-2.2	1.3	-4.0	-5.7	-5.6	-4.7	-5.5	-4.3	-5.7	-4.9	-3.9	-4.1	-5.3	-6.0
Trunk fat-free mass	1.1	6.4	17.9	-1.1	-2.8	-1.6	-4.2	1.2	1.2	-3.4	-3.9	-2.3	-1.6	-3.9	-3.2	-1.4	-2.8	-3.3	-1.9	-1.6	-0.6	-1.8
Trunk predicted mass	1.1	6.4	17.6	-1.1	-2.8	-1.6	-4.2	1.2	1.2	-3.5	-3.9	-2.3	-1.6	-3.9	-3.1	-1.4	-2.8	-3.3	-1.8	-1.6	-0.6	-1.8
Exposure to tobacco smoke outside home	1.1	1.5	3.5	-1.4	-0.5	-0.7	-1.1	-1.6	-0.6	0.7	-0.6	-1.7	-1.9	-1.0	-1.2	-1.5	-1.3	-1.2	-1.2	-1.3	-1.4	-1.4
Wheeze or whistling in the chest in last year	1.1	2.1	3.9	-1.9	-0.6	-0.4	-1.4	-0.8	-0.7	1.7	-1.2	-1.6	-1.7	-1.5	-1.8	-1.3	-1.9	-1.2	-1.8	-0.6	-1.5	-2.0
Leg fat-free mass (right)	1.1	5.7	16.2	-1.3	-2.5	-1.5	-4.0	0.9	1.0	-2.7	-3.5	-2.5	-1.5	-3.7	-3.1	-1.2	-2.8	-3.1	-1.9	-1.2	-0.7	-1.9
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	5.5	1.8	-1.0	-0.7	0.0	2.3	-0.5	-1.4	-0.3	1.2	1.5	0.6	1.1	0.1	1.3	0.0	-0.1	-0.2	0.4	1.7
Smoking status: Current	1.1	1.7	3.7	-1.4	-0.6	-1.4	-0.9	-1.0	-0.7	0.2	-1.0	-1.6	-1.9	-1.2	-1.4	-1.4	-1.4	-1.4	-1.7	-1.2	-1.4	-1.4
Whole body water mass	1.1	6.3	17.8	-1.2	-2.7	-1.6	-4.2	1.1	1.3	-3.1	-3.8	-2.4	-1.6	-3.9	-3.2	-1.3	-2.9	-3.2	-1.9	-1.4	-0.6	-1.9
Coronary Artery Disease (CAD)	1.0	1.2	4.5	0.3	0.3	-0.3	1.5	0.4	-2.1	2.1	1.3	1.1	0.9	1.7	1.2	0.2	1.1	1.0	0.0	0.1	-0.6	0.5
Heel T-Score	1.0	8.2	13.0	3.2	3.3	3.0	2.8	2.5	0.9	-0.4	2.8	2.4	2.8	3.0	3.3	3.2	3.4	2.9	3.6	2.8	2.9	3.3
Relative age of first facial hair	1.0	2.0	3.6	1.6	1.5	1.4	1.4	1.0	0.5	-0.4	1.4	1.2	1.4	1.5	1.7	1.8	1.7	1.5	1.3	1.9	1.3	1.7
Angina	1.0	1.3	2.7	0.8	1.4	1.2	1.3	0.1	1.4	-0.4	1.6	0.8	0.5	1.3	1.2	1.1	1.2	1.3	1.6	0.9	1.0	1.0
Medication: Metformin	1.0	1.5	7.5	-1.2	-1.1	-2.1	-0.7	-2.7	-0.3	0.1	-0.3	-1.4	-2.1	-0.5	-0.8	-0.7	-0.9	-0.7	0.2	-1.1	-1.0	-1.1
Leg fat-free mass (left)	1.0	5.2	15.0	-1.3	-2.3	-1.4	-3.9	0.8	1.1	-2.6	-3.4	-2.5	-1.5	-3.6	-3.0	-1.0	-2.7	-3.0	-1.6	-1.0	-0.7	-1.9
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	4.9	-1.5	0.1	0.2	-0.1	-1.0	-2.2	2.1	0.5	-1.1	-1.1	0.0	-0.5	-0.4	-0.7	-0.3	-0.3	-0.1	-1.5	-1.2
Supplements: Glucosamine	1.0	1.3	5.9	0.2	-2.2	-2.4	-1.8	-0.0	-0.2	-1.8	-1.7	-0.3	-0.2	-1.2	-0.8	-0.6	-0.5	-1.1	-0.4	-0.9	0.1	-0.0
Leg predicted mass (left)	1.0	5.2	15.0	-1.3	-2.3	-1.5	-3.9	0.7	1.1	-2.6	-3.4	-2.5	-1.5	-3.6	-3.0	-1.0	-2.7	-3.0	-1.6	-1.0	-0.7	-1.9
Nervous feelings	1.0	1.8	3.6	1.6	1.9	1.9	0.9	1.0	1.3	-0.7	1.5	0.7	1.2	1.1	1.4	1.4	1.4	1.3	0.7	1.5	1.6	1.5
Neuroticism score	1.0	2.0	4.4	1.4	2.0	2.1	1.2	2.0	0.7	-0.1	1.4	0.9	1.2	1.2	1.3	1.5	1.3	1.6	0.8	1.6	1.7	1.3
Comparative height size at age 10	1.0	5.8	9.4	-2.6	-1.8	-2.0	-2.4	-1.3	-2.9	0.4	-2.0	-2.9	-2.8	-2.2	-2.5	-2.6	-2.5	-2.8	-1.7	-2.9	-3.1	-2.6
Had major operations	1.0	1.2	9.2	-0.4	-0.9	0.3	-0.6	1.7	-3.0	-0.5	-1.2	-0.2	0.2	-0.8	-0.7	-1.2	-0.6	-0.8	-0.1	-1.7	-0.6	-0.5
Whole body fat-free mass	1.0	5.9	17.1	-1.1	-2.6	-1.5	-4.1	1.2	1.2	-3.2	-3.7	-2.3	-1.5	-3.8	-3.1	-1.2	-2.7	-3.1	-1.7	-1.2	-0.5	-1.7
Back pain experienced in last month	1.0	1.5	4.6	-1.7	-0.8	-1.7	-0.6	-0.8	-2.1	1.3	-0.7	-0.7	-1.2	-0.6	-1.0	-1.2	-1.2	-0.8	0.1	-1.7	-1.3	-1.5
Leg predicted mass (right)	1.0	5.6	15.9	-1.3	-2.5	-1.6	-4.0	1.0	1.1	-2.7	-3.5	-2.4	-1.5	-3.7	-3.1	-1.2	-2.8	-3.0	-1.8	-1.2	-0.7	-1.9
Tinnitus: Yes, now most or all of the time	1.0	1.2	3.3	0.0	-1.3	-1.2	-1.8	-0.6	0.6	-1.7	-1.2	-1.1	-1.4	-1.5	-1.0	-0.9	-0.8	-1.2	-1.2	-0.9	0.1	-0.3
Basal metabolic rate	1.0	5.3	15.1	-1.2	-2.3	-1.4	-3.9	1.0	1.2	-2.8	-3.5	-2.3	-1.4	-3.6	-3.0	-1.1	-2.7	-3.0	-1.6	-1.1	-0.5	-1.8
Heart disease (siblings)	1.0	1.3	4.6	0.1	-1.6	-2.1	-1.6	0.4	-1.1	-1.5	-1.4	-0.7	-0.7	-1.1	-0.7	-1.1	-0.5	-1.4	-0.1	-1.6	-0.5	-0.1
Arm predicted mass (left)	1.0	5.3	14.4	-1.1	-2.5	-1.6	-3.8	1.0	1.7	-2.7	-3.5	-2.2	-1.4	-3.6	-3.0	-1.2	-2.6	-2.9	-1.6	-1.3	-0.4	-1.7
Reaction Time	0.9	1.8	4.8	1.0	1.2	0.7	2.2	-0.4	-1.2	0.9	1.8	1.4	1.4	1.9	1.7	1.4	1.6	1.3	0.6	1.2	0.3	1.3
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	1.8	-1.0	-1.2	-1.0	-1.2	-1.2	0.5	-0.3	-0.9	-1.2	-1.3	-1.1	-1.1	-1.0	-1.2	-0.9	-0.8	-0.8	-0.8	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	4.0	2.0	1.3	0.4	1.4	0.4	1.1	-0.5	1.2	1.4	1.3	1.5	1.8	1.5	1.9	1.4	1.6	1.1	1.6	2.0
Number of incorrect matches in round	0.9	1.5	3.5	0.8	1.2	1.9	1.2	0.2	1.6	0.8	1.5	1.3	0.7	1.2	1.1	1.2	1.0	1.6	1.3	1.3	1.6	0.8
Pulse wave Arterial Stiffness index	0.9	1.0	3.6	-1.8	0.6	0.6	0.2	-0.6	-1.4	1.9	0.4	-1.1	-0.9	0.0	-0.7	-0.7	-0.9	-0.3	-0.3	-0.4	-1.7	-1.5
Birth weight of first child	0.9	1.6	4.1	-0.8	-0.7	-0.1	-1.7	0.3	0.8	-1.8	-1.7	-2.0	-0.9	-1.9	-1.7	-0.1	-1.5	-1.7	-0.6	-0.1	-0.7	-1.1
Shortness of breath walking on level ground	0.9	1.1	3.7	0.1	-0.7	0.5	-1.8	1.0	-0.9	-1.9	-1.4	-1.2	-0.3	-1.7	-1.2	-0.1	-1.0	-1.2	-1.2	0.1	0.3	-0.3
Angina (self-reported)	0.9	1.2	2.4	0.9	1.3	1.1	1.2	0.3	1.3	-0.7	1.5	0.8	0.6	1.2	1.2	1.0	1.2	1.3	1.6	0.8	1.1	1.0
Qualifications: nursing, teaching	0.9	1.4	2.5	1.1	1.6	0.3	1.1	0.2	1.2	-0.2	1.4	1.1	1.0	1.4	1.3	1.1	1.3	1.6	1.4	1.1	1.4	1.2
Eye problems/disorders: Cataract	0.9	1.1	3.6	-0.7	-1.3	-1.9	-1.0	-1.3	0.5	-0.6	-1.1	-1.1	-0.9	-1.2	-1.1	-0.9	-1.1	-0.9	-0.8	-0.9	-0.5	-0.8
Asthma (self-reported)	0.9	1.8	3.3	1.8	0.6	1.0	0.7	1.7	-0.2	-0.8	0.8	1.6	1.5	1.1	1.5	1.8	1.6	1.0	1.8	1.4	1.5	1.8
Medication: Lisinopril	0.9	1.1	5.0	1.5	-1.6	-2.0	-0.0	1.3	0.0	-2.2	-0.8	1.0	0.9	-0.0	0.6	-0.0	0.8	-0.4	0.3	-0.6	0.4	1.3
Arm fat-free mass (left)	0.9	4.6	13.0	-0.8	-2.4	-1.7	-3.6	1.1	1.6	-2.9	-3.4	-1.8	-1.2	-3.4	-2.7	-1.0	-2.3	-2.7	-1.3	-1.2	-0.2	-1.4
Crohns Disease (2017)	0.8	1.8	8.2	-0.3	-2.0	-1.9	-0.9	1.1	-2.9	-1.0	-1.6	-0.3	0.2	-0.9	-0.7	-1.7	-0.6	-1.6	-0.6	-2.0	-1.4	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	4.1	-1.4	-0.0	0.5	-1.0	-1.3	0.1	0.9	-0.2	-1.6	-2.0	-0.9	-1.2	-0.2	-1.3	-0.2	-1.4	0.7	-0.2	-1.5
Had menopause	0.8	1.0	7.4	-1.3	0.5	-1.2	0.1	-2.7	0.4	1.5	0.4	-0.7	-1.3	0.1	-0.4	-0.7	-0.6	-0.0	-0.2	-0.6	-1.0	-1.1
Hip circumference	0.8	3.4	7.3	-2.1	-0.9	-0.8	-2.5	-0.8	0.6	-0.5	-2.1	-2.3	-1.8	-2.7	-2.7	-1.1	-2.6	-2.1	-1.7	-0.9	-1.2	-2.4
Falls in the last year	0.8	1.0	2.1	-0.9	-1.0	0.2	-1.2	0.4	-0.2	-0.6	-1.2	-1.2	-1.2	-1.4	-1.3	-0.7	-1.3	-1.2	-1.4	-0.2	-1.0	-1.1
Mouth/teeth dental problems: Dentures	0.8	1.3	3.0	-1.3	0.1	-0.7	-0.5	-1.7	-0.5	1.2	-0.5	-1.6	-1.1	-0.8	-1.1	-1.3	-1.1	-1.1	-1.7	-1.0	-1.6	-1.2
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	2.4	-0.5	-1.6	-1.1	-1.4	0.8	-1.1	-0.4	-1.3	-0.8	-0.4	-1.2	-1.0	-1.1	-0.9	-1.1	-1.2	-1.3	-0.4	-0.6
Ever highly irritable/argumentative for 2 days	0.8	1.0	2.1	-0.6	-0.5	0.6	-1.3	1.2	-0.5	-1.2	-1.2	-1.4	-0.7	-1.4	-1.2	-0.6	-1.1	-1.3	-1.0	-0.5	-0.3	-0.8
Heart disease (mother)	0.8	1.0	3.0	0.4	0.3	-0.3	1.5	0.2	-0.5	1.7	1.2	1.2	1.1	1.5	1.2	0.6	1.1	0.9	1.4	0.2	-0.0	0.7
Pulse rate, automated reading	0.8	2.7	7.0	-1.8	-0.8	-0.5	-2.3	-2.0	-0.2	0.9	-1.0	-2.5	-2.6	-1.8	-2.0	-0.7	-2.0	-1.3	-2.0	0.1	-1.1	-1.9
Overall health rating	0.8	1.7	3.7	-1.2	-1.5	-1.0	-1.9	0.4	-1.4	-0.5	-1.4	-1.6	-1.2	-1.8	-1.7	-1.0	-1.7	-1.4	-1.0	-0.8	-0.7	-1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	3.6	1.7	1.4	0.8	1.1	1.2	-1.8	-0.1	1.4	1.3	1.5	1.6	1.8	1.0	1.8	1.0	0.9	0.7	0.6	1.9
Mother’s age at death	0.8	0.9	4.3	0.5	2.1	1.2	0.7	-0.6	1.0	0.8	1.1	0.3	0.4	0.8	0.7	1.4	0.6	0.9	1.0	1.5	0.7	0.5
Bipolar Disorder or Schizophrenia	0.7	1.8	4.1	-1.7	-1.3	-2.0	-1.3	-0.7	-0.1	0.2	-1.6	-1.3	-1.5	-1.2	-1.4	-1.4	-1.4	-1.3	-0.5	-1.8	-1.4	-1.5
Alzheimer’s Disease (in mother)	0.7	0.9	2.7	-0.5	-1.3	-1.6	-1.0	-0.7	-1.0	-1.1	-1.1	-0.7	-0.8	-1.0	-0.9	-0.6	-0.8	-1.0	-0.0	-0.7	-0.7	-0.6
Verbal and Numeric Reasoning (VNR)	0.7	1.7	5.8	1.0	1.5	2.4	1.4	1.7	0.1	-0.1	1.3	1.4	1.9	1.2	1.2	0.9	1.2	1.3	1.3	0.7	1.2	1.1
Systolic blood pressure, automated reading	0.7	2.0	10.7	0.1	1.0	-0.7	1.7	-1.3	0.3	3.3	2.0	1.5	0.5	2.0	1.4	0.6	1.2	1.9	1.3	0.5	0.3	0.5
Supplements: Zinc	0.7	0.7	2.0	1.4	0.1	-0.0	0.3	0.6	-0.3	-1.2	0.3	0.9	1.0	0.6	1.0	0.5	1.1	0.6	1.2	0.2	1.1	1.3
Impedance of leg (right)	0.7	3.6	10.3	-0.1	2.3	1.0	3.2	-1.3	-2.4	3.0	2.8	1.2	0.5	2.9	2.1	1.0	1.7	1.9	1.9	0.5	-0.7	0.6
Impedance of leg (left)	0.7	3.4	9.5	-0.1	2.2	1.0	3.1	-1.3	-2.3	3.1	2.7	1.2	0.5	2.9	2.0	0.8	1.6	1.9	1.7	0.4	-0.7	0.6
Hearing difficulty/problems with background noise	0.7	1.2	6.4	0.1	1.5	2.5	1.2	1.3	0.6	0.6	1.6	0.5	0.2	1.3	1.0	0.7	0.8	1.2	-0.2	1.0	0.1	0.4
Financial difficulties in last 2 years	0.7	0.9	2.1	-0.2	-1.3	0.1	-1.4	1.4	-0.0	-1.0	-1.4	-0.4	-0.4	-1.3	-1.0	-1.2	-0.9	-0.9	-0.8	-1.2	0.3	-0.5
Medication: Ramipril	0.7	0.9	2.6	0.8	0.2	0.4	1.2	0.7	-1.1	0.6	0.8	1.3	1.1	1.1	1.1	0.5	1.0	1.0	1.6	-0.0	0.9	0.9
Medication: Simvastatin	0.7	1.0	3.2	-0.3	1.5	0.4	1.4	-1.8	-0.1	1.6	1.6	0.3	-0.0	1.5	0.9	0.2	0.7	1.1	1.1	-0.0	-0.1	0.0
Weight	0.7	3.3	8.4	-1.6	-1.1	-0.9	-2.9	0.0	0.9	-1.1	-2.4	-2.3	-1.4	-2.9	-2.7	-0.9	-2.5	-2.3	-1.4	-0.8	-0.8	-2.0
Impedance of arm (right)	0.7	3.2	11.2	-0.9	2.0	0.9	2.9	-2.1	-2.6	3.3	2.7	0.5	0.0	2.6	1.5	0.3	1.0	1.6	1.2	0.2	-1.4	-0.2
Impedance of arm (left)	0.7	3.4	13.0	-1.2	2.0	0.9	2.6	-2.4	-3.2	3.6	2.6	0.1	-0.3	2.4	1.3	0.2	0.8	1.4	1.3	0.1	-1.6	-0.4
Standing height	0.7	7.4	12.5	-3.1	-2.0	-1.4	-3.4	-1.1	-1.7	-1.1	-3.1	-3.5	-2.9	-3.3	-3.5	-2.2	-3.4	-3.4	-1.8	-2.3	-2.8	-3.3
Breastfed as a baby	0.7	0.9	3.5	0.1	1.1	1.7	1.3	0.5	0.6	1.9	1.3	0.7	0.7	1.1	0.8	-0.1	0.8	0.9	-0.8	0.6	-0.3	0.4
Birth weight	0.7	1.6	8.1	0.5	-0.2	-0.3	-1.9	-0.3	1.9	-2.9	-1.4	-1.6	-0.5	-1.9	-1.2	0.6	-0.8	-1.1	-0.2	0.6	1.1	-0.0
Comparative body size at age 10	0.7	2.0	4.5	1.8	0.9	0.5	1.3	0.3	1.5	-0.8	1.1	1.6	1.7	1.3	1.6	1.6	1.6	1.4	2.1	1.1	1.9	1.7
Pulse wave peak to peak time	0.7	0.8	3.2	1.5	-0.6	-0.6	-0.3	0.4	1.3	-1.8	-0.5	0.8	0.7	-0.1	0.5	0.5	0.7	0.2	0.3	0.2	1.5	1.3
Neck or shoulder pain in last month	0.7	1.0	3.8	0.1	-1.4	-0.3	-1.1	2.0	-1.9	-1.3	-1.2	0.0	0.1	-0.8	-0.5	-0.9	-0.3	-1.0	-0.1	-1.1	-0.5	0.0
Migraine (self-reported)	0.7	0.9	1.6	-0.8	-0.7	0.9	-1.2	1.0	-0.5	-0.4	-1.1	-0.9	-0.4	-1.3	-1.2	-1.1	-1.2	-0.8	-0.9	-1.1	-0.2	-1.0
Age at last live birth	0.7	1.0	3.1	-0.9	-0.4	-0.1	-0.9	0.1	-0.6	-0.2	-0.9	-1.8	-1.0	-1.1	-1.1	-1.0	-1.1	-1.4	-1.6	-0.7	-1.4	-0.9
Ever taken oral contraceptive pill	0.7	0.7	2.3	-1.3	1.1	0.9	0.5	-1.2	0.4	1.5	0.8	-0.7	-1.2	0.4	-0.2	0.3	-0.5	0.1	-0.1	0.7	-1.2	-1.0
Number of operations (self-reported)	0.7	1.0	6.3	0.6	0.5	1.4	0.4	1.7	-2.5	-0.1	0.7	0.6	0.6	1.0	0.9	1.0	0.9	0.5	1.0	0.8	-0.2	0.8
Diastolic blood pressure, automated reading	0.7	2.0	6.7	0.6	1.8	0.3	1.6	-0.9	0.8	2.6	1.8	1.6	1.0	1.8	1.4	1.1	1.3	2.1	1.1	1.2	1.2	0.8
Basal cell carcinoma (self-reported)	0.7	0.8	2.4	1.4	-1.0	-0.0	-0.3	1.5	-1.4	-0.6	0.1	1.3	0.3	0.6	0.9	0.3	1.1	0.6	0.5	0.0	1.3	1.3
Impedance of whole body	0.7	3.7	13.9	-0.8	2.3	1.2	3.1	-2.0	-3.0	3.7	2.8	0.6	0.0	2.8	1.6	0.4	1.2	1.8	1.6	0.2	-1.3	-0.1
Schizophrenia vs Biploar Disorder	0.6	0.8	2.2	0.4	0.5	0.6	0.3	-0.4	1.2	0.4	0.0	0.1	0.3	0.9	0.9	1.2	0.9	1.4	1.1	1.5	1.4	0.9
Major Depression (MDD)	0.6	0.8	5.9	0.9	1.2	2.4	0.4	1.6	0.9	-0.3	0.8	0.3	0.7	0.0	0.0	0.0	0.0	0.0	-0.6	0.0	0.8	0.0
Hypothyroidism (self reported)	0.6	1.4	4.0	2.0	0.4	0.2	0.3	0.5	0.9	-1.5	0.6	1.2	1.5	0.7	1.2	1.1	1.4	1.0	1.0	0.7	2.0	1.8
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.8	0.5	0.7	0.9	0.8	1.2	-1.3	1.2	1.3	0.5	0.6	1.1	1.0	0.8	0.9	0.9	0.7	0.9	0.2	0.6
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.4	0.3	1.3	1.5	0.5	-0.2	0.6	0.8	1.1	0.4	0.1	0.9	0.7	1.0	0.6	1.0	0.2	1.5	0.3	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.5	3.6	1.9	1.1	0.6	1.0	0.5	0.0	-0.8	1.1	1.1	1.1	1.2	1.6	1.2	1.7	1.1	1.4	0.7	1.4	1.9
Asthma	0.6	1.3	2.8	1.6	0.5	0.9	0.3	1.7	-0.2	-0.8	0.5	1.3	1.2	0.7	1.1	1.5	1.2	0.7	1.6	1.2	1.3	1.5
Peak expiratory flow (PEF)	0.6	1.3	3.2	1.6	0.9	0.7	0.8	1.8	-0.7	-0.6	0.8	1.0	1.5	1.0	1.3	1.4	1.4	0.7	0.3	1.2	0.9	1.6
Pulse wave reflection index	0.6	0.8	4.8	-1.2	0.4	0.6	1.1	-0.0	-1.4	2.2	0.8	0.1	-0.3	0.8	0.1	-0.6	-0.1	0.3	0.4	-0.8	-1.3	-0.8
Headache pain in last month	0.6	1.0	3.6	-0.7	-1.0	-0.4	-1.1	1.4	-1.9	-0.7	-1.1	-0.8	-0.6	-1.0	-0.9	-0.9	-0.9	-1.1	-0.5	-0.9	-0.9	-0.8
Gout (self-reported)	0.6	0.8	2.4	-0.2	1.4	1.6	0.6	-1.5	0.2	1.4	1.4	-0.4	-0.8	0.6	0.3	0.0	0.1	0.9	-1.2	0.8	-0.0	-0.1
Medication: Seretide 50 evohaler	0.6	0.7	2.6	0.4	-1.2	-0.9	-0.7	1.6	0.0	-1.6	-1.2	0.5	0.8	-0.7	-0.3	0.0	-0.1	-0.6	0.9	-0.5	0.5	0.2
Suffer from ‘nerves’	0.6	1.0	2.5	1.1	1.2	1.5	0.7	0.7	1.0	-0.2	1.0	0.7	0.4	0.9	1.0	1.1	1.0	1.4	0.4	1.1	1.6	1.0
Commuting to job workplace: Car/motor vehicle	0.6	0.7	6.0	-0.5	1.3	0.9	0.8	-0.1	1.1	2.4	0.7	0.4	0.5	0.6	0.2	0.3	0.1	0.7	0.9	0.3	-0.1	-0.4
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.7	0.0	1.1	0.2	1.3	-1.1	0.4	0.5	1.1	0.6	0.2	1.1	0.8	1.1	0.7	0.9	1.1	1.0	0.1	0.3
Mineral and other dietary supplements	0.6	0.8	4.1	-0.9	1.9	1.7	1.2	-0.2	0.4	2.0	0.8	-0.6	-0.1	0.3	-0.2	-0.1	-0.4	0.2	-0.3	0.4	-0.8	-0.8
Osteoarthritis (self-reported)	0.6	0.8	3.6	-0.8	1.5	1.9	0.3	-0.4	0.5	1.5	1.1	-0.4	-0.6	0.4	-0.1	0.7	-0.2	0.9	-0.4	1.4	0.1	-0.7
Miserableness	0.6	1.0	4.1	0.6	1.2	2.0	0.9	1.8	-0.0	0.5	1.0	1.0	0.7	0.9	0.8	0.4	0.7	1.2	0.8	0.4	1.2	0.6
Guilty feelings	0.6	0.9	6.3	0.8	-0.3	0.7	-1.0	2.5	-0.8	-2.2	-0.8	-0.3	1.0	-0.9	-0.3	0.0	-0.1	-0.7	-0.4	0.0	0.4	0.5
Financial situation satisfaction	0.6	0.7	5.2	-0.4	0.6	2.3	-0.9	-0.3	-0.3	-0.7	-0.4	-1.3	-0.4	-1.1	-0.9	-0.1	-0.9	-0.6	-0.5	0.2	0.2	-0.6
Supplements: Fish oil (including cod liver oil)	0.6	0.8	3.6	-0.3	-1.5	-1.9	-1.5	-1.0	0.4	-1.0	-0.9	-0.5	-1.1	-0.8	-0.7	-0.3	-0.5	-0.6	-0.4	-0.5	0.1	-0.4
Ever smoked	0.6	1.0	5.8	-0.3	2.1	2.4	0.8	-0.5	0.0	1.3	1.5	-0.2	0.0	0.7	0.3	0.9	0.2	1.0	-0.1	1.4	0.2	-0.2
Body Mass Index (BMI) (2010)	0.5	0.7	1.9	1.1	0.7	0.5	0.2	0.4	0.6	-0.8	0.5	0.6	0.9	0.4	0.7	1.4	0.8	0.8	0.8	1.4	1.3	0.9
Ever used hormone-replacement therapy (HRT)	0.5	0.6	3.5	-1.2	0.3	-0.2	-0.5	-1.9	-0.3	1.3	0.3	-0.7	-1.1	0.0	-0.5	-0.0	-0.6	0.1	-0.2	0.3	-0.7	-1.1
Relative age voice broke	0.5	0.8	2.0	0.5	0.9	0.4	1.3	0.9	0.5	0.8	1.1	1.1	1.0	1.4	1.2	0.5	1.1	1.0	-0.0	0.8	-0.1	0.8
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	4.3	0.2	0.7	1.4	0.3	1.3	-2.1	0.0	0.8	0.1	0.3	0.6	0.5	0.7	0.5	0.3	0.2	0.9	-0.2	0.3
Trunk fat mass	0.5	2.3	5.6	-2.2	-0.0	-0.1	-1.8	-1.1	0.0	0.8	-1.2	-2.2	-1.5	-2.0	-2.3	-0.9	-2.3	-1.5	-1.0	-0.8	-1.2	-2.4
Past tobacco smoking	0.5	0.9	6.9	0.3	-2.0	-2.6	-0.7	0.4	-0.3	-1.3	-1.3	0.2	-0.1	-0.6	-0.3	-0.5	-0.1	-0.9	0.4	-1.0	-0.3	0.2
Alcohol usually taken with meals	0.5	0.8	2.0	0.8	0.6	0.3	0.4	-0.3	0.8	0.2	0.6	1.1	0.8	0.7	0.8	1.4	0.8	1.1	1.1	1.4	1.2	0.8
Had other major operations	0.5	0.6	2.1	-0.7	1.3	0.3	0.3	-0.5	-1.4	1.2	1.2	-0.3	-0.7	0.8	0.3	0.6	0.1	0.4	1.1	0.6	-1.0	-0.4
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.1	-0.3	-0.4	1.1	-1.1	0.9	-0.5	-1.4	-0.7	-0.7	-0.6	-1.1	-0.9	-0.6	-0.8	-0.7	-0.3	-0.6	0.2	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	5.4	0.8	0.1	2.3	-0.5	2.0	-0.1	-1.4	-0.1	-0.0	0.6	-0.4	0.0	0.5	0.1	0.3	-0.1	0.8	1.3	0.6
Number of full brothers	0.5	0.6	1.5	-0.4	-0.6	-1.2	-0.9	0.4	0.0	-0.7	-0.5	-1.1	-1.1	-0.6	-0.5	-0.7	-0.5	-1.1	-0.9	-0.6	-1.1	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.5	0.6	2.6	0.3	-0.8	-0.8	-0.8	0.6	1.6	-1.5	-0.9	-0.0	0.0	-0.8	-0.5	-0.5	-0.3	-0.2	-0.1	-0.8	0.9	0.0
Qualifications: College or University degree	0.5	1.7	5.4	-0.2	2.3	0.9	1.3	-2.0	1.8	1.3	1.8	0.4	-0.2	1.3	0.8	1.4	0.6	1.6	1.2	1.6	0.6	-0.0
Medication for pain relief, constipation, heartburn	0.5	0.9	7.1	0.4	1.5	0.6	0.8	-0.3	2.7	-0.3	0.6	0.2	0.6	0.4	0.4	1.3	0.4	0.6	1.0	1.5	0.6	0.4
Mean time to correctly identify matches	0.5	1.0	2.8	-0.1	1.1	0.1	1.5	-1.6	-1.6	1.7	1.5	0.5	0.3	1.4	0.9	0.4	0.7	0.8	0.3	0.2	-0.5	0.2
Number of full sisters	0.5	0.6	1.5	-0.1	-0.8	-0.2	-1.0	-0.2	0.2	-1.2	-1.1	-0.8	-0.5	-1.2	-0.9	-0.9	-0.7	-1.0	-0.4	-1.0	0.1	-0.3
Smoking status: Previous	0.5	0.8	6.7	0.0	1.7	2.6	0.5	0.1	0.6	0.8	1.1	-0.1	0.5	0.5	0.3	0.5	0.2	0.8	-0.3	0.9	0.5	0.0
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.4	1.1	0.2	0.5	-0.1	0.8	0.3	-0.3	0.5	1.0	0.3	0.7	0.9	0.9	1.0	0.8	0.7	0.9	1.2	1.0
Medication for cholesterol	0.5	0.8	2.5	-0.0	-1.1	-0.4	-0.9	0.6	0.4	-1.6	-1.4	-0.8	-0.2	-1.3	-0.9	-0.5	-0.7	-1.3	-1.0	-0.5	-0.3	-0.2
Wears glasses or contact lenses	0.5	0.6	3.0	0.9	0.1	1.0	-0.3	1.7	-1.4	-1.1	-0.4	0.2	1.0	-0.2	0.2	-0.3	0.4	-0.3	0.1	-0.7	0.5	0.8
Medication: Blood pressure	0.5	1.0	2.6	0.4	0.2	-0.8	1.4	-0.4	0.2	1.5	1.2	1.6	0.4	1.5	1.2	0.9	1.0	1.4	1.2	0.7	0.6	0.6
Irritability	0.5	0.8	3.8	0.2	1.4	2.0	0.8	0.4	1.2	0.5	1.1	0.1	0.4	0.5	0.4	0.9	0.3	0.9	0.1	1.5	0.7	0.2
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.5	-0.0	0.8	0.2	1.0	-0.3	-0.1	1.2	0.9	0.5	0.2	1.0	0.7	0.9	0.5	1.0	1.1	0.9	0.2	0.2
Unable to work because of sickness or disability	0.5	0.7	3.6	1.1	0.3	0.4	-0.2	1.9	0.8	-1.2	-0.1	0.6	1.0	0.0	0.5	0.8	0.6	0.2	0.7	0.7	1.1	1.0
Neuroticism (Nagel 2018)	0.4	0.9	5.1	0.6	1.3	2.2	0.8	2.2	0.1	0.3	0.8	0.3	1.0	0.5	0.5	0.7	0.5	0.8	-0.1	1.0	0.8	0.5
Respiratory disease	0.4	1.0	2.7	1.3	0.2	0.4	0.2	1.6	-0.5	-0.9	0.2	1.4	1.5	0.6	0.9	1.2	1.0	0.5	1.4	0.8	1.1	1.2
Ever had hysterectomy (womb removed)	0.4	0.4	1.4	-0.5	0.0	0.4	-0.7	0.1	-1.1	-0.5	-0.6	-0.9	-0.3	-0.8	-0.7	-0.3	-0.6	-0.7	-1.2	0.2	-0.5	-0.5
Average weekly fortified wine intake	0.4	0.5	2.2	-0.8	0.1	0.5	-0.8	-0.7	-1.5	0.4	-0.0	-0.8	-0.8	-0.4	-0.6	-0.6	-0.6	-0.4	0.2	-0.6	-0.8	-0.8
Maternal smoking around birth	0.4	0.5	2.4	-0.3	-0.8	0.5	-1.2	1.6	0.4	-0.5	-1.0	-0.3	-0.2	-0.9	-0.8	-0.6	-0.7	-0.7	0.0	-0.6	-0.1	-0.5
Medication: Atenolol	0.4	0.4	3.0	0.6	0.4	0.0	0.4	-0.3	0.1	-0.3	0.6	0.8	0.5	0.6	0.6	-0.0	0.6	0.7	1.7	-0.8	1.0	0.6
Heart attack	0.4	0.5	2.7	0.4	-0.9	-0.3	-0.3	-0.8	1.3	-1.6	-0.3	0.3	-0.3	-0.2	-0.0	-0.4	0.0	-0.0	1.0	-1.0	0.8	0.3
Length of working week for main job	0.4	0.4	3.2	0.2	0.7	0.8	-0.4	-0.5	1.8	-1.1	-0.2	-0.5	0.2	-0.6	-0.4	0.1	-0.3	-0.1	-0.5	0.5	0.8	-0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.6	0.9	-0.1	0.9	-0.4	1.6	0.3	-1.3	-0.2	0.2	0.3	0.0	0.3	0.8	0.4	0.3	0.9	0.9	1.0	0.7
Hair/balding pattern: Pattern 4	0.4	0.9	2.1	-1.0	-1.0	-1.2	-1.0	-1.5	-0.3	0.4	-0.9	-0.7	-1.2	-0.7	-0.8	-1.0	-0.9	-0.7	0.1	-1.3	-0.8	-1.0
Medication: Paracetamol	0.4	0.7	6.0	0.4	-1.3	-0.1	-0.7	1.4	-2.5	-0.5	-0.6	0.3	0.5	-0.3	-0.0	-0.5	0.1	-0.5	0.2	-0.9	0.0	0.4
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	2.6	1.5	0.7	0.7	0.1	0.1	1.0	-1.2	0.6	0.2	0.7	0.3	0.7	0.9	0.9	0.7	0.3	0.9	1.6	1.3
Medication: Ventolin 100micrograms inhaler	0.4	0.5	3.7	0.9	-0.5	-0.4	-0.8	-0.2	-0.4	-1.9	-0.8	-0.3	0.1	-0.7	-0.1	0.4	-0.0	-0.6	0.1	0.2	0.8	0.6
High blood pressure (siblings)	0.4	0.6	1.9	1.0	0.1	-0.8	0.4	0.0	-0.4	-0.2	0.6	1.1	1.4	0.7	0.8	0.4	0.9	0.6	1.4	-0.2	0.8	1.0
Medication: Omeprazole	0.4	0.4	2.1	-0.8	-0.4	-0.5	-0.6	-0.4	1.2	0.6	-0.3	-0.4	-0.7	-0.5	-0.7	-0.4	-0.7	-0.1	-1.4	0.1	-0.0	-0.8
Supplements: Vitamin C	0.4	0.5	2.0	1.1	0.2	0.9	0.3	1.4	0.6	-0.5	0.1	1.0	0.4	0.4	0.7	0.3	0.8	0.6	0.2	0.2	1.2	1.0
Loneliness, isolation	0.4	0.5	2.7	0.1	1.4	1.6	0.4	0.1	0.2	0.6	1.0	-0.2	-0.1	0.5	0.4	0.9	0.3	0.7	0.8	1.1	0.5	0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	4.3	-0.5	-1.3	-1.4	-0.2	-0.4	-2.1	-0.2	-0.5	0.2	-0.4	-0.0	-0.2	-0.6	-0.3	-0.3	0.5	-1.0	-0.8	-0.4
Osteoporosis (self-reported)	0.4	0.5	1.7	1.1	-1.0	0.2	-0.5	1.1	-1.0	-1.3	-0.9	0.5	0.5	-0.4	0.1	0.0	0.3	-0.5	0.1	-0.4	0.8	0.8
Medication: Paracetamol	0.4	0.6	5.3	-0.5	-1.1	-0.2	-0.9	0.4	-2.3	0.1	-0.7	-0.4	-0.2	-0.7	-0.6	-0.8	-0.6	-0.7	-0.3	-1.0	-0.4	-0.5
Ever depressed for a whole week	0.4	0.4	1.8	-0.4	0.4	1.3	-1.1	0.6	0.4	-0.6	-0.4	-0.8	-0.4	-0.8	-0.7	0.0	-0.7	-0.4	-0.9	0.5	0.0	-0.6
Myopia	0.4	0.5	3.9	0.2	0.8	1.1	0.0	-0.4	0.1	-0.5	0.7	-0.7	-0.3	0.0	0.1	1.5	0.2	-0.1	0.0	2.0	-0.3	0.2
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.1	0.3	-1.0	-0.4	-0.4	-0.9	1.4	-1.4	-0.3	0.2	-0.5	-0.3	-0.1	-0.5	-0.1	-0.1	0.8	-1.1	0.7	0.1
Alzheimer’s Disease (including proxy)	0.3	0.5	4.2	0.5	-0.8	-1.5	-0.5	-0.2	-0.2	-2.0	-0.5	-0.1	-0.1	-0.4	-0.1	0.1	0.0	-0.4	0.6	-0.2	0.4	0.4
Age at First Birth	0.3	0.4	4.2	0.9	-0.3	0.2	-0.4	0.2	-0.3	-2.0	-0.4	-0.0	-0.1	-0.2	0.3	0.4	0.4	-0.3	-0.5	0.4	0.4	0.9
LDL Cholesterol	0.3	0.4	2.7	-0.3	-0.6	-1.7	-0.8	-0.5	-1.1	0.3	-0.6	0.1	0.2	-0.4	-0.3	-0.6	-0.3	-0.6	0.5	-1.1	-0.4	-0.2
Triglycerides	0.3	0.5	1.6	0.5	0.7	0.2	0.7	-0.2	-0.6	1.0	1.3	0.6	0.5	1.0	0.9	0.4	0.9	0.9	0.5	0.6	0.4	0.7
Blood Eosinophil Count	0.3	2.3	10.0	2.4	-0.8	-0.5	0.5	1.7	-0.7	-3.2	-0.2	1.9	1.9	0.5	1.3	0.5	1.6	0.2	1.6	-0.7	1.7	2.2
Allergy or Eczema	0.3	0.7	3.3	-1.3	-0.2	0.9	-0.2	-0.8	-1.0	1.8	0.1	-0.6	-1.4	-0.0	-0.5	0.1	-0.7	-0.2	0.0	0.3	-1.2	-1.1
Neuroticism	0.3	0.7	4.2	0.3	1.3	2.1	0.6	1.9	0.6	-0.1	0.4	-0.1	0.5	0.1	0.2	0.5	0.2	0.7	-0.2	0.9	1.0	0.2
Average weekly spirits intake	0.3	0.4	1.4	-1.0	0.8	0.9	-0.2	-0.6	-0.6	1.2	-0.1	-0.7	-0.3	-0.5	-0.7	-0.4	-0.8	-0.2	-0.2	-0.4	-0.4	-1.0
Medication for hormone replacement therapy	0.3	0.3	1.0	-0.3	-0.1	-0.0	-1.0	-1.0	-0.7	-0.1	-0.3	-1.0	-0.4	-0.6	-0.6	-0.7	-0.5	-0.4	-0.4	-0.6	-0.0	-0.4
Trunk fat percentage	0.3	1.2	4.4	-2.0	1.0	0.4	-0.4	-1.4	-0.3	2.1	0.1	-1.4	-1.0	-0.7	-1.2	-0.3	-1.4	-0.4	-0.2	-0.2	-1.0	-1.9
Fed-up feelings	0.3	0.5	1.8	-0.0	0.0	0.8	-0.9	1.3	-0.4	0.0	-0.4	-1.1	-0.6	-0.9	-0.7	-0.5	-0.5	-0.6	-1.1	-0.1	0.2	-0.2
Qualifications: CSEs or equivalent	0.3	0.4	1.3	1.0	0.4	0.8	0.6	0.6	0.5	-0.1	0.4	0.3	0.8	0.4	0.6	1.0	0.7	0.3	0.1	1.1	0.5	0.9
Serious illness, injury or assault to yourself	0.3	0.4	1.3	0.3	0.4	1.1	0.3	-0.3	-0.1	0.4	1.1	0.5	0.1	0.7	0.6	0.8	0.5	1.0	0.2	1.0	0.6	0.4
Stomach or abdominal pain in last month	0.3	0.3	2.3	0.1	0.3	0.0	0.3	-0.1	0.8	0.4	0.5	0.3	-0.2	0.4	0.3	1.2	0.2	0.8	0.3	1.5	0.6	0.1
High blood pressure (mother)	0.3	0.4	1.6	0.7	0.4	-0.2	-0.2	-1.0	1.3	-0.8	0.8	-0.4	-0.5	0.2	0.4	0.8	0.4	0.3	0.5	0.8	0.8	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	2.2	-0.9	1.1	1.5	0.2	-0.3	0.6	1.5	0.6	-0.6	-0.7	0.2	-0.2	0.2	-0.4	0.6	-0.7	0.8	-0.0	-0.8
Forced expiratory volume in 1-second (FEV1)	0.3	0.9	3.3	0.0	-0.5	-0.3	-1.3	1.2	-1.8	-1.1	-1.3	-0.9	0.0	-1.1	-0.7	-0.4	-0.5	-1.4	-1.4	-0.4	-0.8	-0.1
Happiness	0.3	0.4	2.9	-0.3	0.9	1.7	0.3	-0.4	-0.9	1.2	0.7	-0.3	-0.0	0.1	-0.1	0.1	-0.1	0.4	-0.2	0.4	0.2	-0.3
Prospective memory result	0.3	0.3	4.5	0.1	-0.6	-2.1	-0.0	0.3	-0.2	0.1	-0.1	0.2	-0.3	0.4	0.3	0.4	0.3	-0.2	0.4	0.1	-0.6	0.2
Illnesses of mother	0.3	0.3	2.1	-0.4	-0.1	1.2	-0.0	1.4	-0.3	0.0	-0.5	0.1	0.4	-0.4	-0.4	-0.4	-0.5	-0.1	-0.9	0.0	-0.1	-0.5
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	2.5	0.7	0.3	-0.3	0.1	0.8	1.0	0.1	0.2	0.6	0.7	0.3	0.5	1.3	0.5	0.5	-0.2	1.6	0.7	0.7
Health satisfaction	0.3	0.4	1.3	0.5	0.1	0.6	-1.0	0.4	-1.1	-0.7	-0.2	-0.2	0.2	-0.6	-0.3	0.9	-0.1	0.0	0.1	1.0	1.0	0.3
Emphysema/chronic bronchitis	0.3	0.3	1.4	1.0	-0.6	-1.2	-0.0	-0.1	0.5	-0.8	-0.5	0.5	0.7	-0.1	0.3	0.1	0.5	0.1	-0.5	0.1	0.7	0.8
Medication: Blood pressure	0.3	0.5	1.5	-0.1	-0.9	-0.1	-0.7	-0.0	-1.0	-1.2	-0.8	-0.4	-0.3	-0.7	-0.5	-1.0	-0.4	-0.7	-0.0	-1.2	-0.3	-0.2
Medication: Allopurinol	0.3	0.4	1.1	0.6	1.1	0.9	0.6	-0.6	-0.4	0.9	1.1	-0.1	0.1	0.6	0.7	0.1	0.6	0.5	-0.7	0.3	0.3	0.6
Whole body fat mass	0.3	1.3	3.3	-1.6	0.2	0.3	-1.5	-0.5	0.5	0.5	-1.0	-1.7	-0.8	-1.7	-1.8	-0.3	-1.8	-1.2	-0.7	-0.3	-0.6	-1.8
Chest pain or discomfort	0.3	0.4	2.0	0.6	-0.1	0.0	0.4	0.7	1.4	-1.0	0.3	0.6	0.5	0.4	0.5	0.8	0.6	0.4	0.8	0.6	0.4	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	2.7	0.2	-1.0	-1.6	-0.2	0.6	0.0	-0.7	-0.9	0.2	-0.1	-0.3	-0.1	-0.7	-0.0	-0.4	-0.5	-0.7	-0.0	0.2
Medication: Aspirin	0.3	0.4	3.3	-0.4	-0.6	-1.2	-0.3	-1.8	0.2	0.1	-0.1	-0.1	-0.9	-0.1	-0.2	-0.6	-0.3	0.1	-0.1	-0.7	0.0	-0.4
Illnesses of father: Heart disease	0.3	0.4	1.0	0.1	0.8	0.9	0.2	-0.1	-0.3	0.9	1.0	0.2	-0.0	0.8	0.6	0.5	0.5	0.8	1.0	0.6	0.2	0.2
Average weekly red wine intake	0.3	0.5	2.1	-0.4	-0.7	-1.0	-0.8	-1.4	-0.3	-0.2	-0.7	-0.6	-0.7	-0.7	-0.7	-0.7	-0.6	-0.5	-0.2	-0.9	-0.0	-0.5
Medication: Aspirin	0.3	0.3	3.6	-0.2	0.1	-0.9	0.2	-1.9	0.2	0.3	0.5	0.1	-0.7	0.4	0.2	-0.3	0.1	0.5	0.2	-0.3	0.2	-0.1
Medication: Bendroflumethiazide	0.3	0.4	2.0	-0.4	-0.8	-1.4	0.2	-0.7	-0.7	0.8	-0.1	0.5	-0.5	0.3	0.1	-0.6	-0.0	-0.1	0.3	-1.0	-0.8	-0.3
Cholesterol lowering medication	0.3	0.4	1.3	0.1	0.8	-0.4	0.6	-0.9	-0.6	0.8	0.9	0.4	0.1	0.9	0.7	0.4	0.6	0.7	1.1	0.2	0.1	0.3
Depressed Affect (Nagel 2018)	0.2	0.5	2.7	-0.7	0.8	1.6	-0.1	1.0	-0.4	0.8	0.0	-0.9	-0.5	-0.4	-0.6	-0.3	-0.7	-0.0	-0.5	0.1	-0.1	-0.8
Primary Biliary Cirrhosis	0.2	0.3	1.3	0.7	0.6	0.7	0.1	1.1	0.4	-0.5	0.3	0.3	0.4	0.3	0.4	0.4	0.6	0.6	0.2	0.5	0.9	0.6
Rheumatoid Arthritis	0.2	0.2	0.7	0.0	0.7	0.1	0.6	-0.6	0.7	0.3	0.4	-0.1	0.5	0.0	0.0	0.8	0.0	0.0	0.8	0.8	0.0	0.0
Blood Red Count	0.2	1.5	10.4	-0.5	-0.8	-3.2	-0.5	0.9	0.2	-0.7	-1.8	-0.6	0.2	-1.1	-0.9	-1.1	-0.8	-1.8	0.3	-1.9	-1.2	-0.5
Smoking Status	0.2	0.5	2.6	-0.4	0.1	1.0	-0.6	0.7	-0.5	0.0	-0.5	-0.8	-0.5	-0.8	-0.7	-0.4	-0.7	-0.6	-1.6	-0.2	-0.2	-0.5
Hand grip strength (left)	0.2	0.6	1.8	-0.6	-0.8	0.6	-1.0	1.3	-0.2	-0.5	-1.2	-0.5	-0.8	-0.9	-0.9	-0.0	-0.8	-0.8	-1.4	0.4	-0.5	-0.7
Number of treatments/medications taken	0.2	0.4	3.5	0.5	-0.4	-0.3	-0.1	0.6	-1.9	-0.2	0.2	0.5	0.4	0.4	0.5	-0.6	0.5	0.3	0.6	-1.1	0.4	0.5
Diabetes (father)	0.2	0.2	1.0	0.0	-0.0	0.5	-0.1	0.2	1.0	-0.7	-0.5	-0.3	0.5	-0.4	-0.3	0.2	-0.3	-0.7	-0.1	-0.0	-0.2	-0.0
High blood pressure	0.2	0.4	1.4	0.1	-0.4	-0.5	0.7	-0.1	-0.3	1.2	0.7	1.2	0.5	1.0	0.7	0.0	0.6	0.9	1.0	-0.2	0.2	0.3
Medication: Levothyroxine sodium	0.2	0.4	1.7	0.5	0.9	0.4	0.1	-1.3	0.9	-0.3	0.7	-0.3	-0.0	0.2	0.3	0.7	0.3	0.5	0.4	0.7	0.8	0.5
Body mass index (BMI)	0.2	0.7	3.3	-0.3	-0.0	-0.2	-1.4	0.4	1.8	-0.6	-1.1	-0.8	-0.1	-1.5	-1.2	0.1	-1.0	-0.8	-0.6	0.2	0.5	-0.6
Hair/balding pattern: Pattern 2	0.2	0.3	0.6	0.4	0.4	0.2	0.8	0.4	-0.2	0.1	0.5	0.7	0.3	0.7	0.6	0.4	0.6	0.6	0.7	0.4	0.3	0.5
Forced vital capacity (FVC)	0.2	0.8	2.4	-0.4	-0.4	-0.4	-1.5	0.4	-1.2	-0.9	-1.3	-1.1	-0.4	-1.2	-1.0	-0.3	-0.9	-1.3	-1.1	-0.3	-0.7	-0.5
Qualifications: None of the above	0.2	0.4	1.6	0.3	-1.1	-0.2	-0.8	1.3	-0.7	-0.8	-0.9	0.0	0.4	-0.7	-0.4	-0.4	-0.2	-0.6	-0.3	-0.6	0.1	0.1
Fluid intelligence score	0.2	0.4	1.5	-0.2	0.5	1.2	0.9	1.1	-0.6	0.6	0.3	0.7	1.2	0.4	0.2	-0.6	0.2	0.4	0.2	-0.7	-0.1	-0.1
Illnesses of siblings	0.2	0.2	1.1	-0.4	0.2	1.1	0.3	0.4	0.8	0.5	-0.2	-0.3	-0.4	-0.2	-0.3	0.4	-0.4	0.1	-0.5	0.9	-0.1	-0.4
Worrier / anxious feelings	0.2	0.5	4.9	0.4	0.5	1.1	0.3	2.2	-0.5	-0.4	0.3	0.3	0.7	0.3	0.4	0.4	0.4	0.3	-0.1	0.3	0.4	0.4
Pulse rate	0.2	0.4	1.6	-0.2	0.1	0.6	-0.8	-0.5	-0.1	-0.5	-0.4	-1.1	-0.9	-0.8	-0.6	-0.0	-0.6	-0.5	-1.3	0.6	-0.1	-0.4
Noisy workplace	0.2	0.2	1.9	0.4	0.0	-0.4	-0.4	1.2	-1.4	-0.3	-0.2	-0.2	-0.0	-0.2	0.1	0.1	0.1	-0.4	-0.2	0.1	-0.0	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.7	-0.3	0.5	0.5	-0.6	0.7	-0.8	0.6	-0.3	-0.3	0.3	-0.4	-0.4	0.5	-0.4	-0.1	-0.2	0.6	0.0	-0.4
Medication: Cholesterol lowering	0.2	0.4	1.7	0.1	0.6	0.5	0.9	-1.3	-0.4	-0.1	1.1	0.0	-0.1	0.7	0.5	-0.6	0.4	0.4	0.7	-1.0	-0.0	0.2
Depression (self-reported)	0.2	0.2	1.1	0.3	-0.0	0.4	0.3	1.1	0.6	-0.5	0.1	0.4	0.2	0.2	0.3	0.1	0.3	0.4	0.6	-0.1	0.7	0.3
Medication: Lansoprazole	0.2	0.2	1.3	0.3	0.8	-0.0	-0.0	-0.6	-1.1	0.3	0.7	-0.6	-0.6	0.2	0.3	0.1	0.3	-0.1	0.3	-0.1	-0.0	0.4
Lung cancer (father)	0.2	0.2	0.9	-0.5	-0.3	-0.6	-0.5	0.1	-0.1	0.2	-0.4	-0.5	-1.0	-0.5	-0.5	-0.4	-0.6	-0.2	-0.6	-0.3	-0.3	-0.6
Arm fat mass (right)	0.2	0.8	2.2	-0.9	-0.0	-0.1	-1.4	0.1	1.1	-0.1	-1.0	-1.1	-0.5	-1.5	-1.4	-0.0	-1.4	-0.9	-0.5	0.0	0.0	-1.2
Blood clot in the leg (DVT)	0.2	0.2	0.7	-0.7	-0.4	-0.5	-0.0	0.4	-0.3	0.7	-0.5	-0.4	-0.4	-0.2	-0.4	0.2	-0.5	-0.5	0.1	0.2	-0.9	-0.6
Body fat percentage	0.2	0.7	3.6	-1.3	1.3	0.8	-0.1	-0.9	0.2	1.9	0.3	-0.9	-0.4	-0.4	-0.8	0.1	-1.0	-0.1	0.0	0.2	-0.5	-1.3
Age at first live birth	0.2	0.3	1.7	-0.3	1.2	0.6	0.7	-1.3	-0.0	0.4	0.8	-0.7	-0.4	0.3	0.1	0.3	0.1	-0.0	-0.0	0.3	-0.6	-0.1
Leg fat mass (right)	0.2	0.9	2.6	-1.0	0.2	0.1	-1.5	-0.2	1.1	-0.0	-1.0	-1.3	-0.6	-1.6	-1.5	0.1	-1.4	-1.1	-0.6	0.1	-0.2	-1.2
Hypertension (Self-reported)	0.2	0.5	1.5	0.3	-0.3	-0.6	0.9	-0.6	0.0	1.0	0.8	1.2	0.5	1.1	0.8	0.2	0.7	1.1	1.1	0.0	0.5	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.9	0.1	0.7	0.8	0.8	0.5	-0.3	1.0	0.8	0.5	0.4	0.6	0.5	-0.1	0.4	0.6	0.3	-0.0	0.2	0.3
Illnesses of siblings: Diabetes	0.2	0.2	2.0	0.5	0.0	0.4	-0.4	-0.2	0.1	-1.4	0.2	-0.3	-0.3	-0.0	0.2	0.3	0.2	-0.0	0.2	0.2	0.4	0.5
Friendships satisfaction	0.2	0.2	0.9	0.6	0.7	0.6	0.1	0.1	0.1	0.1	0.2	0.3	0.5	0.1	0.3	0.6	0.4	0.4	0.8	0.5	0.9	0.5
Illnesses of father: None of the above (group 1)	0.2	0.2	0.7	-0.3	-0.4	0.1	-0.3	0.4	-0.8	-0.3	-0.5	-0.5	-0.4	-0.5	-0.5	-0.2	-0.4	-0.6	-0.8	-0.1	-0.7	-0.3
Arm fat mass (left)	0.2	0.9	2.6	-1.1	0.1	-0.1	-1.4	-0.2	1.2	0.0	-1.0	-1.3	-0.7	-1.6	-1.6	-0.2	-1.5	-1.0	-0.4	-0.1	-0.0	-1.3
Number of self-reported non-cancer illnesses	0.2	0.3	1.4	-0.2	0.2	0.7	0.3	0.8	-1.0	1.2	0.6	0.5	0.4	0.7	0.4	0.1	0.3	0.5	0.9	0.1	-0.1	-0.1
Commuting to job workplace: Public transport	0.2	0.2	1.3	-0.7	0.0	-0.5	0.5	-1.1	-0.3	0.2	0.0	-0.4	-0.5	0.0	-0.2	-0.3	-0.3	-0.1	-0.2	-0.4	-0.5	-0.6
Medication: Atorvastatin	0.2	0.3	1.7	0.1	-0.8	-1.3	-0.1	-1.1	0.7	-0.5	0.1	0.1	-0.4	-0.0	0.1	-0.6	0.1	-0.2	0.3	-0.8	-0.2	0.2
Illnesses of father: High blood pressure	0.2	0.2	0.9	0.7	-0.6	-0.5	-0.6	0.2	0.3	-0.7	-0.3	0.5	0.5	-0.1	0.2	0.2	0.2	0.2	0.4	0.0	1.0	0.5
Alcohol drinker status: Never	0.2	0.3	1.2	0.6	0.1	-0.3	0.0	0.8	-1.1	0.1	0.5	0.2	0.3	0.5	0.6	-0.6	0.6	-0.1	0.1	-0.8	-0.2	0.7
Pain experienced in last month	0.2	0.3	1.7	-0.4	0.7	0.6	0.5	-1.3	0.6	0.6	0.6	-0.1	-0.1	0.5	0.2	-0.0	0.1	0.2	-0.7	0.5	-0.6	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.8	-0.8	-0.5	-0.5	-0.2	0.4	-0.3	0.6	-0.7	-0.6	-0.3	-0.5	-0.6	0.1	-0.7	-0.7	-0.1	0.1	-0.9	-0.8
Leg fat mass (left)	0.2	0.8	2.5	-0.8	0.2	0.1	-1.5	0.1	1.2	-0.1	-1.0	-1.2	-0.5	-1.6	-1.4	0.1	-1.3	-1.1	-0.6	0.1	-0.1	-1.1
Bipolar Disorder (2018)	0.1	0.2	0.7	0.1	0.2	-0.8	0.5	0.3	0.4	-0.1	0.4	0.6	0.4	0.3	0.2	-0.2	0.2	0.0	0.7	-0.8	-0.0	0.1
Intelligence (Savage-Jansen 2018)	0.1	0.3	1.9	-0.5	0.7	1.4	0.5	-0.1	-0.2	0.8	0.5	0.2	0.3	0.4	0.1	-0.4	-0.1	0.6	0.2	-0.4	0.1	-0.4
Ovarian Cancer	0.1	0.2	1.0	-0.6	0.6	-0.3	0.2	-0.6	0.4	1.0	0.4	-0.1	-0.1	0.2	-0.1	0.3	-0.2	0.2	-0.3	0.6	-0.2	-0.5
Prostate Cancer	0.1	0.2	1.1	-0.1	-0.5	0.7	-0.5	1.0	-0.6	-0.8	-0.3	-0.2	-0.0	-0.4	-0.3	0.1	-0.4	-0.2	-0.5	0.1	-0.0	-0.2
Bipolar Disorder (2011)	0.1	0.1	1.0	0.4	-0.2	-1.0	0.2	0.4	0.4	0.0	-0.1	0.6	0.6	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Neuroticism (2016)	0.1	0.1	0.6	-0.1	-0.1	-0.1	-0.2	0.3	-0.7	-0.0	-0.0	-0.2	-0.7	-0.1	-0.1	-0.7	-0.2	0.1	-0.1	-0.8	0.4	-0.1
Blood White Count	0.1	0.8	2.3	1.3	-1.5	-1.2	-0.2	0.9	-0.8	-1.4	-0.8	1.0	1.2	-0.1	0.4	-0.1	0.6	-0.2	0.2	-0.7	0.9	1.1
BMI	0.1	0.4	2.7	0.2	0.7	0.0	-0.4	1.0	1.6	-0.4	-0.2	-0.0	0.6	-0.6	-0.3	0.7	-0.2	-0.1	-0.1	0.7	0.7	0.0
Lung FEV1/FVC ratio	0.1	0.5	3.8	0.4	-0.0	0.7	0.4	1.5	-1.9	0.6	0.3	-0.0	0.5	0.3	0.5	-0.4	0.5	-0.2	-0.8	-0.2	-0.8	0.6
Hair Pigment	0.1	1.7	5.8	0.9	-1.9	-0.6	-1.2	2.4	-0.5	-1.6	-2.1	-0.1	1.5	-1.5	-0.7	-1.2	-0.4	-1.7	-0.3	-1.7	0.4	0.5
Tanning	0.1	1.7	4.5	1.9	-0.2	-0.1	0.5	2.1	0.2	-1.1	0.3	1.9	1.5	0.9	1.4	1.7	1.6	0.6	1.3	1.2	1.1	1.9
Severe depression (siblings)	0.1	0.1	0.8	0.0	0.8	0.9	0.2	0.0	0.4	0.2	0.5	-0.1	0.3	0.1	0.0	0.4	0.1	0.3	0.1	0.6	0.3	0.0
Hand grip strength (right)	0.1	0.3	1.3	-0.1	-0.6	0.0	-0.8	0.8	0.2	-0.9	-1.0	-0.2	-0.4	-0.7	-0.5	0.1	-0.4	-0.5	-1.1	0.5	-0.1	-0.2
Taking other prescription medications	0.1	0.1	1.2	0.4	-0.0	0.3	-0.0	1.1	-0.7	0.0	0.3	0.2	0.1	0.3	0.4	-0.0	0.4	0.2	0.1	-0.1	0.1	0.4
Hayfever, allergic rhinitis or eczema	0.1	0.2	1.1	-0.6	-0.4	1.0	-0.0	-0.1	-0.5	1.0	0.2	-0.2	-0.9	0.1	-0.2	0.5	-0.2	0.1	0.3	0.5	-0.4	-0.5
Waist circumference	0.1	0.4	0.9	-0.9	0.9	0.7	-0.5	0.1	0.3	0.6	-0.1	-0.9	-0.5	-0.7	-0.8	0.2	-0.9	-0.5	-0.2	0.3	-0.5	-0.9
Allergy	0.1	0.3	1.5	0.4	1.2	-0.1	0.8	0.0	0.5	-0.0	0.8	0.3	0.8	0.7	0.6	-0.3	0.6	0.5	-0.0	-0.2	0.1	0.5
Hayfever/allergic rhinitis (self-reported)	0.1	0.2	0.9	-0.2	-0.6	-0.9	-0.4	0.6	-0.2	0.7	-0.7	0.3	0.0	-0.2	-0.2	0.1	-0.2	-0.4	-0.0	-0.0	-0.5	-0.2
Arm fat percentage (right)	0.1	0.4	2.0	-0.6	1.3	0.7	0.2	-0.4	0.7	1.4	0.5	-0.2	0.1	-0.0	-0.3	0.5	-0.4	0.3	0.2	0.6	0.2	-0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	2.7	0.5	-0.3	-0.8	-0.5	1.3	-1.6	-0.6	-0.6	0.2	0.5	-0.2	0.1	0.2	0.2	-0.5	-0.4	-0.1	-0.2	0.4
Medication: Amlodipine	0.1	0.2	1.8	0.1	0.2	0.9	0.2	-0.3	-1.4	-0.1	0.3	-0.1	-0.1	0.1	0.1	-0.2	0.1	0.0	-0.0	-0.2	-0.0	0.1
Forced vital capacity (FVC), Best measure	0.1	0.5	1.8	-0.3	-0.5	-1.1	-1.2	0.4	-1.3	-0.5	-1.0	-0.3	-0.2	-0.7	-0.6	-0.1	-0.5	-0.8	-0.6	-0.3	-0.4	-0.3
Leg fat percentage (right)	0.1	0.2	1.2	-0.4	1.1	0.5	0.0	-0.3	0.7	1.1	0.3	-0.2	0.1	-0.2	-0.3	0.6	-0.3	0.1	0.3	0.6	0.1	-0.4
Worry too long after embarrassment	0.1	0.1	0.6	-0.1	0.1	0.4	-0.1	0.3	-0.8	0.2	-0.1	-0.1	0.5	-0.1	-0.1	-0.3	-0.1	-0.0	-0.6	-0.2	-0.1	-0.1
Number of children fathered	0.1	0.1	0.9	0.3	0.2	0.6	-0.2	0.9	0.4	-0.5	-0.3	0.3	0.3	-0.0	0.1	0.4	0.2	-0.1	-0.2	0.6	0.1	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.5	0.6	0.1	-0.0	-0.0	-0.2	0.3	-0.4	0.2	-0.0	0.2	0.0	0.2	0.0	0.3	0.0	-0.7	0.1	0.3	0.5
Family relationship satisfaction	0.1	0.2	0.8	-0.1	-0.4	-0.1	-0.5	-0.4	-0.9	-0.4	-0.5	-0.2	0.2	-0.5	-0.4	-0.3	-0.4	-0.4	-0.3	-0.4	-0.0	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.1	0.2	-0.4	-0.0	0.3	-0.5	0.3	-0.3	-0.1	-0.5	-0.3	-0.2	-0.4	-0.4	0.3	-0.4	-0.5	0.2	0.1	-0.4	-0.4
Arm fat percentage (left)	0.1	0.4	2.3	-0.9	1.2	0.7	-0.1	-0.6	0.6	1.5	0.3	-0.7	-0.2	-0.3	-0.6	0.3	-0.7	0.0	0.0	0.4	-0.0	-0.9
Mood swings	0.1	0.3	2.8	-0.1	0.4	0.7	0.6	1.7	-0.0	0.5	0.4	0.1	0.6	0.2	0.1	0.1	0.0	0.4	-0.1	0.3	0.1	-0.1
Long-standing illness, disability or infirmity	0.1	0.2	2.0	-0.1	-0.2	0.1	-0.2	0.4	-1.4	-0.1	-0.3	-0.2	0.2	-0.2	-0.2	-0.2	-0.2	-0.3	0.0	-0.2	-0.4	-0.1
Leg fat percentage (left)	0.1	0.2	1.0	-0.3	1.0	0.5	-0.1	-0.1	0.9	1.0	0.2	-0.2	0.3	-0.3	-0.3	0.6	-0.3	0.0	0.1	0.5	0.3	-0.3
Risk taking	0.1	0.2	0.9	0.0	-0.3	0.0	-0.5	0.9	-0.3	-0.7	-0.5	-0.1	0.1	-0.6	-0.4	-0.0	-0.3	-0.5	-0.3	-0.1	0.1	-0.1
Commuting to job workplace: Cycle	0.1	0.1	0.7	0.0	0.0	-0.3	0.0	0.0	-0.0	-0.6	-0.2	-0.2	0.4	-0.0	-0.0	-0.1	0.0	-0.2	-0.8	0.1	-0.3	0.0
Vascular/heart problems diagnosed by doctor	0.1	0.4	1.5	0.1	0.2	0.2	-0.8	0.1	0.4	-1.2	-0.7	-1.0	-0.3	-1.0	-0.6	0.1	-0.5	-0.8	-1.0	0.3	0.0	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.9	-0.1	0.0	0.0	-0.3	0.1	0.8	0.4	-0.0	0.1	-0.1	-0.2	-0.2	0.1	-0.2	0.1	-0.9	0.4	0.4	-0.2
Lung FVC	0.0	0.2	1.1	0.1	0.7	0.5	-0.2	-0.3	-1.1	0.5	0.8	0.3	-0.5	0.6	0.4	0.2	0.4	0.6	-0.4	0.3	0.2	0.2
Townsend deprivation index at recruitment	0.0	0.0	0.1	0.1	0.1	-0.0	0.1	-0.2	-0.1	-0.2	0.3	0.1	-0.2	0.1	0.1	0.2	0.1	0.0	0.1	0.3	-0.0	0.1

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