Best TWAS P=2.09e-17 · Best GWAS P=1.3e-15 conditioned to 0.0018
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | ZHX2 | 0.21 | 0.20 | lasso | 4 | 0.20 | 6.8e-63 | -7.6 | 8.5 | 2.1e-17 | 0.67 | 0.04 | 0.96 | TRUE |
2 | YFS | Blood | ZHX2 | 0.31 | 0.22 | enet | 30 | 0.25 | 1.1e-82 | -7.6 | -7.9 | 2.7e-15 | -0.60 | 0.04 | 0.96 | FALSE |