Best TWAS P=1.62e-07 · Best GWAS P=4e-08 conditioned to 0.0414
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | GGTA1P | 0.15 | 0.10 | enet | 12 | 0.12 | 2.3e-07 | -5.1 | -5.2 | 2.6e-07 | 0.79 | 0.07 | 0.92 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | GGTA1P | 0.31 | 0.40 | enet | 13 | 0.43 | 4.3e-21 | -5.1 | -5.2 | 1.6e-07 | 0.83 | 0.08 | 0.92 | TRUE |
| 3 | GTEx | Heart Left Ventricle | GGTA1P | 0.30 | 0.43 | lasso | 13 | 0.44 | 2.1e-25 | -5.1 | -5.2 | 2.0e-07 | 0.80 | 0.07 | 0.93 | FALSE |
| 4 | GTEx | Muscle Skeletal | GGTA1P | 0.13 | 0.16 | lasso | 5 | 0.16 | 1.3e-15 | -5.1 | -5.2 | 2.0e-07 | 0.78 | 0.06 | 0.94 | FALSE |
| 5 | GTEx | Whole Blood | GGTA1P | 0.14 | 0.14 | lasso | 7 | 0.13 | 1.1e-11 | -5.1 | 5.2 | 2.0e-07 | -0.76 | 0.06 | 0.94 | FALSE |