Best TWAS P=5.43e-08 · Best GWAS P=1.27e-08 conditioned to 0.000132
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | PBX3 | 0.05 | 0.02 | enet | 7 | 0.00 | 1.4e-01 | -5.1 | 5.4 | 7.8e-08 | -0.80 | 0.09 | 0.78 | FALSE |
| 2 | GTEx | Esophagus Muscularis | PBX3 | 0.12 | 0.08 | lasso | 7 | 0.09 | 4.2e-06 | 4.0 | 5.2 | 1.7e-07 | -0.58 | 0.26 | 0.74 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PBX3 | 0.04 | 0.07 | lasso | 3 | 0.06 | 6.7e-07 | 5.4 | 5.4 | 5.4e-08 | -0.40 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PBX3 | 0.03 | 0.03 | blup | 65 | 0.04 | 5.4e-05 | 4.4 | 5.3 | 1.3e-07 | -0.48 | 0.13 | 0.85 | FALSE |