TWAS hub - PBX3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1660	0.0500	3.1e-06	0.078	NA	0.083	NA	0.097	5.7e-07	NA	2.6e-07	NA	2.4e-08
2	GTEx	Artery Tibial	0.1110	0.0444	1.4e-03	0.072	NA	0.043	NA	0.065	2.5e-06	NA	2.6e-04	NA	8.1e-06
3	GTEx	Cells Transformed fibroblasts	0.0550	0.0260	4.3e-03	0.022	NA	0.004	NA	-0.003	8.4e-03	NA	1.4e-01	NA	6.2e-01
4	GTEx	Colon Sigmoid	0.2330	0.0740	1.0e-04	0.221	NA	0.094	NA	0.165	2.4e-08	NA	3.3e-04	NA	1.8e-06
5	GTEx	Colon Transverse	0.1120	0.0510	5.0e-03	0.010	NA	0.015	NA	0.016	1.1e-01	NA	6.2e-02	NA	5.5e-02
6	GTEx	Esophagus Gastroesophageal Junction	0.2150	0.0690	2.6e-05	0.188	NA	0.102	NA	0.139	2.4e-07	NA	1.6e-04	NA	1.0e-05
7	GTEx	Esophagus Muscularis	0.1190	0.0370	1.7e-05	0.083	NA	0.083	NA	0.090	9.6e-06	NA	9.2e-06	NA	4.2e-06
8	GTEx	Heart Atrial Appendage	0.0990	0.0430	6.6e-03	0.084	NA	0.036	NA	0.037	1.3e-04	NA	9.4e-03	NA	9.0e-03
9	GTEx	Heart Left Ventricle	0.2053	0.0586	1.8e-06	0.221	NA	0.161	NA	0.206	5.2e-12	NA	6.2e-09	NA	3.3e-11
10	GTEx	Nerve Tibial	0.0774	0.0358	8.0e-03	0.028	NA	0.032	NA	0.024	4.5e-03	NA	2.3e-03	NA	7.9e-03
11	GTEx	Pancreas	0.1300	0.0500	9.5e-04	0.016	NA	0.000	NA	-0.002	6.6e-02	NA	3.2e-01	NA	3.9e-01
12	GTEx	Skin Not Sun Exposed Suprapubic	0.1230	0.0420	2.4e-04	0.134	NA	0.123	NA	0.127	8.4e-08	NA	2.9e-07	NA	1.8e-07
13	GTEx	Testis	0.1900	0.0560	8.6e-06	0.218	NA	0.169	NA	0.195	4.7e-10	NA	5.6e-08	NA	4.7e-09
14	GTEx	Thyroid	0.0700	0.0300	1.6e-03	0.003	NA	0.007	NA	0.011	1.7e-01	NA	9.5e-02	NA	4.7e-02
15	YFS	Blood	0.0505	0.0157	9.8e-07	0.027	0.016	0.033	0.026	0.032	3.0e-09	3.3e-06	5.7e-11	3.7e-09	7.3e-11
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0399	0.0217	1.3e-05	0.067	0.047	0.044	NA	0.056	5.1e-08	5.4e-06	9.5e-06	NA	6.7e-07
17	TCGA	Lung Squamous Cell Carcinoma	0.0269	0.0217	9.5e-03	0.002	0.011	0.015	NA	0.001	1.6e-01	1.9e-02	6.2e-03	NA	2.2e-01
18	TCGA	Prostate Adenocarcinoma	0.0312	0.0160	3.7e-05	0.030	0.039	0.032	NA	0.032	3.7e-04	5.4e-05	2.5e-04	NA	2.4e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Overall health rating	14.0	30.0	50.2	-5.5	-5.8	-4.5	-5.2	-4.5	-5.3	-5.8	-5.8	-6.2	-4.6	-3.1	-6.1	-6.1	-6.3	4.2	-7.1	-4.4	-6.5
Smoking Status	12.7	30.5	51.6	-5.5	-6.1	-7.2	-5.3	-4.8	-5.8	-6.2	-6.4	-5.3	-5.1	-5.1	-5.7	-5.5	-6.4	2.3	-4.5	-4.9	-5.7
Smoking status: Current	12.2	19.4	26.7	-4.6	-4.9	-5.2	-4.3	-4.0	-4.6	-4.9	-4.9	-4.3	-3.7	-3.6	-4.6	-4.5	-4.7	3.1	-3.9	-4.1	-4.7
Current tobacco smoking	11.5	18.8	27.0	-4.6	-4.8	-5.2	-4.3	-4.1	-4.5	-4.9	-4.9	-4.2	-3.5	-3.5	-4.5	-4.4	-4.6	3.2	-3.9	-4.1	-4.5
Pulse wave reflection index	11.1	13.7	19.9	-3.9	-4.1	-3.8	-4.0	-4.2	-4.5	-4.0	-3.6	-3.6	-3.7	-1.8	-4.1	-3.7	-3.1	3.3	-3.3	-3.1	-4.0
Unable to work because of sickness or disability	10.4	13.4	19.3	-4.0	-3.7	-3.4	-3.6	-3.0	-3.5	-3.8	-3.9	-4.0	-4.1	-1.9	-4.0	-4.0	-3.5	2.0	-4.4	-3.8	-4.4
Pulse rate, automated reading	8.9	28.7	87.8	4.8	6.1	9.4	5.4	5.5	5.9	6.6	5.0	5.1	3.9	5.1	5.0	5.6	3.4	-4.0	3.7	2.9	5.8
Long-standing illness, disability or infirmity	8.9	13.7	22.7	-3.6	-3.6	-2.6	-3.5	-2.5	-3.9	-3.7	-3.7	-4.4	-3.9	-1.7	-4.0	-4.5	-4.7	2.6	-4.8	-2.9	-4.4
Mouth/teeth dental problems: Dentures	8.4	14.2	26.0	-4.4	-3.5	-3.2	-3.7	-3.1	-3.8	-3.6	-3.6	-3.9	-3.8	-2.6	-3.9	-4.0	-2.8	3.9	-4.4	-5.1	-3.7
Osteoarthritis (self-reported)	8.4	10.9	18.4	-3.1	-3.2	-3.9	-2.9	-2.6	-3.4	-3.8	-3.1	-3.8	-2.1	-3.0	-3.1	-3.8	-4.3	3.1	-3.0	-3.1	-3.7
Average weekly champagne plus white wine intake	8.3	11.4	14.7	3.5	3.8	3.2	3.3	2.8	3.5	3.8	3.5	3.6	3.1	1.7	3.8	3.7	2.6	-3.6	3.8	3.4	3.5
Financial difficulties in last 2 years	7.4	10.0	18.2	-3.1	-3.5	-2.8	-3.6	-2.2	-3.2	-3.2	-3.6	-3.1	-2.3	-2.4	-3.5	-3.4	-4.3	2.0	-3.1	-3.2	-3.2
Hair/balding pattern: Pattern 2	7.2	9.1	14.5	2.7	2.9	2.0	3.0	2.8	3.5	2.9	3.1	3.8	3.2	0.3	3.2	3.7	2.2	-3.2	3.0	3.6	3.4
Age at First Birth	6.9	10.0	13.7	3.5	3.2	2.8	3.3	2.8	3.1	3.4	3.4	3.5	3.4	1.5	3.3	3.2	2.9	-2.7	3.6	2.9	3.7
Medication: Co-codamol	6.7	7.7	12.7	-2.2	-2.5	-1.0	-2.6	-2.3	-2.9	-2.5	-2.6	-3.4	-3.3	-0.7	-3.0	-3.3	-3.6	3.2	-3.5	-2.7	-3.1
Pain all over the body in last month	6.7	7.2	12.1	-2.4	-2.6	-2.1	-2.5	-2.1	-2.9	-2.7	-2.6	-3.5	-2.6	-1.9	-2.8	-3.3	-3.0	1.8	-3.3	-2.2	-3.2
Emphysema/chronic bronchitis	6.7	7.6	12.4	-3.3	-2.7	-3.1	-2.4	-2.3	-2.7	-3.0	-2.6	-3.0	-2.8	-1.0	-2.8	-3.1	-1.5	2.8	-3.5	-2.1	-3.5
Pulse rate	6.3	10.7	23.2	3.4	3.6	4.8	3.3	3.1	3.7	3.7	3.4	3.3	3.2	2.7	3.3	3.3	3.1	-1.7	2.3	2.2	3.2
Maternal smoking around birth	6.2	9.0	13.1	-2.8	-3.4	-2.9	-3.6	-2.8	-3.2	-3.3	-3.3	-2.7	-2.6	-3.4	-3.2	-2.9	-2.7	2.9	-2.7	-2.5	-3.0
Alcohol usually taken with meals	5.9	9.5	16.1	4.0	3.2	3.6	3.4	3.3	3.5	3.1	3.8	2.0	3.7	2.5	3.2	2.4	2.7	-1.3	2.2	3.3	2.7
Qualifications: O levels/GCSEs or equivalent	5.7	9.1	14.1	3.4	3.1	3.7	2.5	2.8	3.1	3.3	3.2	2.8	3.8	1.8	3.2	2.9	1.8	-2.2	3.2	3.4	3.0
Townsend deprivation index at recruitment	5.6	7.9	12.5	-2.7	-2.9	-3.5	-2.6	-1.6	-2.8	-3.0	-2.7	-2.6	-3.0	-2.5	-2.7	-2.8	-3.0	2.9	-3.1	-2.8	-2.9
Reason for reducing amount of alcohol drunk: Health precaution	5.4	6.4	11.6	2.5	2.6	1.4	2.6	2.0	2.5	2.7	2.7	3.1	1.4	0.1	2.8	3.3	3.4	-2.0	3.2	1.7	3.0
Other serious medical condition/disability diagnosed by doctor	5.1	6.6	12.7	-2.2	-2.4	-1.0	-2.6	-2.3	-2.6	-2.2	-2.3	-2.9	-3.1	-1.0	-2.8	-3.0	-3.6	2.6	-3.1	-2.2	-2.8
Hand grip strength (right)	5.1	13.8	22.7	3.2	4.2	4.8	3.0	3.1	3.5	4.7	3.7	4.1	3.0	1.8	3.8	4.2	3.5	-3.5	4.4	2.3	4.6
Mouth/teeth dental problems: Bleeding gums	5.0	6.5	9.7	3.1	2.7	2.2	2.5	2.5	2.5	2.7	2.7	2.3	2.9	0.8	2.9	2.5	1.8	-2.7	3.0	2.5	2.6
Systolic Blood Pressure	4.9	24.3	41.2	4.1	5.5	6.0	4.8	4.2	4.9	5.7	5.2	4.6	4.0	6.4	4.6	5.2	6.1	-3.3	4.2	3.2	5.3
Medication for hormone replacement therapy	4.9	5.4	8.5	-2.2	-2.5	-0.9	-2.7	-1.9	-2.5	-2.1	-2.7	-2.7	-2.4	-0.5	-2.9	-2.6	-2.3	1.4	-2.6	-2.9	-2.3
Serious illness, injury or assault to yourself	4.9	6.0	12.5	-2.5	-2.6	-2.5	-2.5	-2.3	-2.5	-2.4	-2.5	-2.1	-3.5	-2.1	-2.8	-2.4	-1.5	1.2	-2.8	-2.6	-2.2
Hand grip strength (left)	4.8	12.6	19.6	3.3	3.9	4.4	3.0	3.2	3.7	4.4	3.3	3.8	2.9	2.4	3.6	3.8	3.3	-3.4	3.9	2.8	4.0
Mother’s age at death	4.8	6.1	16.3	2.9	2.7	4.0	2.2	2.0	2.4	2.9	2.2	2.1	2.1	3.5	2.3	2.2	1.2	-2.0	2.2	1.4	2.4
Health satisfaction	4.7	6.1	8.8	-2.8	-2.6	-2.5	-2.2	-2.1	-2.3	-2.7	-2.6	-2.6	-2.9	-1.7	-2.7	-2.6	-2.5	1.4	-2.9	-1.9	-3.0
Medication: Seretide 50 evohaler	4.6	5.3	9.1	-2.1	-2.5	-2.5	-2.3	-2.1	-2.5	-2.4	-2.4	-2.6	-1.8	-1.0	-2.5	-2.8	-2.0	1.9	-2.4	-2.0	-3.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	4.6	5.4	11.2	-2.6	-2.5	-3.4	-2.0	-2.4	-2.5	-2.7	-2.4	-1.9	-2.7	-1.5	-2.1	-2.1	-1.7	2.5	-1.5	-2.0	-2.4
Medication: Omeprazole	4.4	5.3	14.1	-2.4	-2.3	-1.7	-2.7	-1.5	-2.4	-2.1	-2.3	-2.1	-3.8	-1.4	-2.6	-2.1	-2.6	1.4	-2.0	-1.9	-2.7
Pain type(s) experienced in last month: Hip pain	4.4	5.6	9.1	-2.4	-2.4	-1.2	-2.0	-2.2	-2.4	-2.4	-2.4	-2.9	-2.4	0.4	-2.7	-3.0	-2.8	2.2	-3.0	-1.7	-2.6
Sensitivity / hurt feelings	4.3	7.3	23.2	-2.5	-2.9	-3.9	-2.1	-1.5	-2.5	-3.2	-2.9	-2.3	-1.0	-3.7	-2.2	-2.6	-4.8	-0.3	-2.1	-1.1	-3.0
Eye problems/disorders: Glaucoma	4.3	5.1	8.8	-2.2	-2.3	-0.5	-2.9	-2.9	-2.4	-2.3	-2.8	-2.3	-3.0	-0.1	-2.5	-2.4	-1.2	1.7	-2.2	-1.7	-2.6
Irritability	4.2	7.1	14.6	2.6	3.0	2.2	3.1	3.1	3.0	2.9	2.6	2.6	3.8	0.9	2.9	2.7	0.2	-2.6	2.3	2.2	2.9
Qualifications: None of the above	4.1	8.9	13.6	-3.1	-3.5	-3.7	-3.0	-2.7	-3.3	-3.6	-3.3	-3.0	-2.5	-1.7	-3.3	-3.0	-2.0	2.4	-3.2	-2.5	-2.8
Falls in the last year	4.1	5.5	10.0	-2.4	-2.6	-3.2	-1.9	-2.0	-2.3	-2.7	-2.3	-2.8	-2.3	-0.2	-2.4	-2.7	-1.1	2.2	-2.7	-1.8	-3.0
Pulse wave peak to peak time	4.0	4.7	8.4	2.2	2.4	0.9	2.5	2.7	2.6	2.2	1.9	2.1	2.4	0.0	2.5	2.1	1.7	-2.9	2.1	1.8	2.2
Respiratory disease	3.8	8.5	14.9	-2.9	-2.6	-2.1	-2.2	-2.5	-3.4	-2.9	-2.4	-3.6	-2.9	-1.1	-2.9	-3.5	-3.4	3.0	-3.9	-2.2	-3.8
Bipolar Disorder (2011)	3.5	3.4	8.2	1.8	1.7	1.1	2.0	1.2	1.8	2.0	1.9	2.1	1.6	0.6	2.0	2.2	2.9	-0.9	2.3	0.8	2.5
Number of full brothers	3.5	4.4	12.1	-2.2	-2.0	-1.7	-1.9	-2.0	-2.2	-2.2	-2.2	-2.4	-3.5	-0.5	-2.3	-2.2	-0.3	1.6	-2.1	-2.3	-2.1
Heart attack	3.4	4.4	9.9	-2.3	-1.7	-3.1	-1.1	-1.2	-1.9	-2.1	-2.0	-2.5	-2.0	-1.8	-1.9	-2.5	-1.9	1.7	-2.6	-2.1	-2.3
Medication: Omeprazole (e.g. Zanprol)	3.4	4.1	10.3	-2.0	-2.0	-1.5	-2.1	-1.4	-2.3	-2.0	-2.1	-2.2	-3.2	-0.5	-2.2	-2.1	-2.3	1.1	-1.7	-1.7	-2.6
Worrier / anxious feelings	3.3	6.2	10.3	3.2	2.6	1.0	3.1	3.1	2.8	2.3	2.3	2.2	3.2	-0.1	2.9	2.2	0.4	-3.1	2.6	2.8	2.2
Glaucoma (self-reported)	3.3	3.8	7.4	-2.0	-2.4	-0.6	-2.7	-2.1	-1.9	-2.2	-2.6	-1.9	-2.1	-0.4	-2.4	-2.1	-1.0	1.6	-2.2	-1.0	-2.1
Pain experienced in last month	3.3	5.5	8.8	2.3	2.4	1.5	2.3	2.3	2.7	2.4	3.0	2.7	2.4	1.3	2.6	2.7	2.6	-1.4	2.7	1.7	2.3
Heart attack/myocardial infarction (self-reported)	3.3	4.3	9.8	-2.2	-1.7	-3.1	-1.2	-1.2	-1.9	-2.1	-2.0	-2.5	-1.9	-1.9	-1.9	-2.5	-1.8	1.7	-2.5	-2.0	-2.2
Tinnitus: Yes, but not now, but have in the past	3.2	3.4	5.2	-2.0	-1.8	-1.8	-1.8	-1.8	-2.0	-2.2	-1.8	-2.1	-2.1	-2.3	-1.6	-1.9	-0.9	1.1	-1.7	-1.4	-2.3
Peak expiratory flow (PEF)	3.2	7.5	14.5	2.7	2.6	3.1	2.2	2.4	2.9	3.2	3.1	3.1	2.1	1.2	2.8	3.1	2.5	-2.4	3.8	2.1	3.1
Medication: Lisinopril	3.2	4.2	8.0	2.3	2.1	1.9	2.1	2.3	2.8	2.4	2.0	2.4	2.0	0.2	2.1	2.3	1.8	-1.5	2.0	1.0	2.2
Qualifications: College or University degree	3.1	9.7	15.6	3.1	3.5	3.9	3.2	3.0	3.3	3.4	3.6	2.7	3.3	3.3	3.4	2.9	2.0	-1.5	3.2	2.8	3.0
Alcohol intake frequency.	3.1	7.2	11.6	-2.9	-2.8	-2.2	-3.1	-2.9	-2.8	-2.6	-2.6	-2.5	-2.8	-1.1	-2.9	-2.8	-2.4	2.5	-2.5	-3.4	-2.8
Pack years adult smoking proportion	3.0	4.6	15.1	-1.8	-2.3	-3.3	-2.1	-1.8	-1.9	-2.0	-2.2	-1.2	-1.6	-3.9	-1.9	-1.6	-2.9	1.3	-0.9	-2.1	-1.5
Reaction Time	2.9	5.6	8.9	1.9	2.5	2.3	2.5	2.2	2.7	2.6	2.3	2.6	1.5	3.0	2.2	2.7	2.6	-2.1	1.8	2.3	2.3
Ever used hormone-replacement therapy (HRT)	2.9	3.7	6.4	-2.1	-2.2	-1.6	-2.3	-1.9	-2.3	-2.1	-2.5	-1.7	-2.1	-1.5	-2.2	-1.5	-1.8	0.8	-1.5	-2.2	-1.6
Pulse wave Arterial Stiffness index	2.9	3.4	7.2	-1.8	-2.0	-0.6	-2.2	-2.4	-2.3	-1.9	-1.5	-1.8	-2.1	0.1	-2.1	-1.7	-1.3	2.7	-1.6	-1.4	-1.8
Commuting to job workplace: Walk	2.9	3.1	6.9	2.6	2.2	1.0	1.8	2.3	1.8	2.3	2.0	1.3	2.1	0.9	2.1	1.3	-0.1	-1.3	2.2	-0.3	1.7
Average weekly fortified wine intake	2.8	3.2	7.4	-1.7	-1.7	-0.7	-2.1	-2.4	-2.2	-1.5	-1.7	-2.0	-2.7	0.0	-1.9	-1.8	-0.3	2.4	-1.4	-1.9	-1.5
Forced expiratory volume in 1-second (FEV1)	2.8	9.4	17.4	3.1	2.9	3.9	2.4	2.4	3.0	3.6	3.2	3.5	2.1	2.1	3.0	3.5	2.9	-2.2	4.2	2.4	3.7
Comparative height size at age 10	2.8	15.6	23.3	3.9	4.3	4.8	4.1	3.3	3.6	4.5	4.2	4.1	3.0	3.2	4.1	4.2	3.9	-3.1	4.0	3.7	4.4
Knee pain experienced in last month	2.8	4.3	7.8	-2.6	-2.4	-2.8	-1.9	-1.8	-2.0	-2.6	-2.2	-2.1	-1.8	-1.3	-2.1	-2.2	-1.1	1.4	-2.2	-1.1	-2.6
Financial situation satisfaction	2.8	3.4	10.4	-1.4	-2.0	-3.2	-1.4	-0.6	-1.1	-2.1	-1.7	-1.2	-2.8	-2.6	-1.6	-1.5	-2.5	0.7	-1.4	-1.5	-1.8
Systolic blood pressure, automated reading	2.7	7.8	14.4	2.1	3.2	3.3	2.7	2.3	2.7	3.3	3.2	2.7	2.4	3.1	2.6	3.1	3.8	-1.4	2.3	1.3	3.2
Ever smoked	2.7	4.8	10.6	-1.8	-2.4	-3.3	-2.2	-1.9	-2.0	-2.5	-3.0	-2.2	-1.7	-1.6	-2.3	-2.4	-2.5	0.0	-1.5	-1.6	-2.4
Schizophrenia (2018)	2.6	5.5	10.7	1.9	2.1	0.5	2.2	1.9	2.5	2.1	2.3	3.1	2.8	-1.2	2.8	3.2	1.2	-2.4	3.3	1.3	3.1
LDL Cholesterol	2.6	4.1	7.5	-1.7	-1.9	-2.7	-2.3	-2.2	-2.1	-1.9	-2.1	-1.7	-2.4	-2.2	-2.0	-1.7	-1.1	2.3	-1.4	-2.6	-1.6
Sitting height	2.6	18.5	29.6	4.9	4.8	5.4	3.7	3.6	3.9	5.2	4.6	4.5	3.8	1.9	4.6	4.6	2.6	-3.6	5.4	3.1	5.3
Lung cancer (father)	2.6	3.0	5.9	-1.7	-1.9	-1.7	-1.9	-2.4	-1.8	-1.7	-1.9	-1.4	-1.4	-2.0	-1.8	-1.4	-1.7	1.2	-1.4	-2.0	-1.4
Standing height	2.6	26.0	39.4	5.3	5.7	6.3	4.8	3.9	4.9	6.2	5.4	5.6	4.4	2.8	5.4	5.6	4.0	-4.4	5.9	3.5	6.1
Medication: Amlodipine	2.6	3.7	10.4	1.3	2.6	3.2	1.8	1.8	1.7	2.6	2.2	1.9	0.1	2.6	1.9	2.3	0.3	-1.1	1.5	0.1	2.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.6	3.1	7.1	-2.0	-1.7	-1.1	-1.7	-1.5	-2.2	-1.9	-1.7	-2.0	-2.7	0.1	-1.9	-2.0	-1.1	1.5	-1.7	-0.8	-2.2
Past tobacco smoking	2.5	4.5	11.6	1.6	2.2	3.4	2.0	1.3	1.8	2.3	2.8	2.0	1.6	2.6	2.0	2.1	2.9	0.7	1.4	1.8	2.2
Time employed in main current job	2.5	2.9	5.7	1.8	1.3	0.8	1.8	1.6	2.0	1.4	1.6	1.7	2.2	0.2	1.7	1.5	2.4	-2.1	1.4	2.3	1.7
Happiness	2.5	3.0	5.9	-1.8	-2.4	-2.2	-2.0	-1.4	-1.4	-2.1	-1.9	-1.3	-1.1	-1.9	-2.0	-1.5	-1.9	1.2	-1.6	-1.2	-1.6
Mean time to correctly identify matches	2.5	4.8	9.5	2.0	2.4	2.2	2.3	2.0	2.4	2.6	2.0	2.3	1.5	3.1	2.0	2.3	2.4	-1.4	1.5	1.9	2.2
Osteoporosis (self-reported)	2.5	3.1	6.0	-1.9	-1.6	-1.4	-1.2	-1.7	-1.6	-1.6	-1.5	-1.9	-1.9	-1.5	-1.7	-1.9	-2.0	1.6	-2.2	-2.4	-1.8
Age started oral contraceptive pill	2.5	3.1	5.9	1.7	2.1	2.4	2.0	1.3	1.6	1.9	1.9	1.4	1.4	1.1	2.0	1.8	1.5	-1.6	1.5	1.7	2.1
Wheeze or whistling in the chest in last year	2.4	4.3	8.1	-2.4	-2.1	-1.5	-1.8	-1.5	-2.0	-2.3	-2.0	-2.4	-1.8	0.0	-2.2	-2.5	-2.2	1.7	-2.8	-2.0	-2.6
Leg pain on walking	2.4	3.0	4.8	-1.8	-2.1	-1.3	-2.0	-1.3	-1.8	-1.9	-1.9	-1.9	-0.9	0.0	-2.2	-2.1	-1.9	1.6	-1.9	-1.0	-1.9
Schizophrenia (2014)	2.3	5.2	9.8	1.8	2.1	0.1	2.4	2.1	2.5	2.0	2.1	3.1	2.7	-1.3	2.7	3.0	0.9	-2.4	3.0	1.1	2.9
Frequency of unenthusiasm / disinterest in last 2 weeks	2.3	3.1	5.0	-1.6	-2.0	-1.2	-1.6	-1.1	-1.6	-2.0	-2.0	-2.1	-1.8	-0.1	-2.1	-2.1	-2.2	0.8	-2.2	-1.3	-2.1
Forced expiratory volume in 1-second (FEV1), Best measure	2.3	7.5	15.1	2.7	2.7	3.0	2.1	2.0	2.4	3.2	2.7	3.5	1.5	1.7	2.8	3.4	2.7	-2.0	3.9	1.9	3.5
Blood clot in the leg (DVT)	2.3	3.0	4.8	-1.9	-1.9	-2.1	-1.1	-1.0	-1.4	-2.1	-1.5	-1.9	-1.9	-0.7	-1.7	-1.9	-1.6	1.6	-2.2	-1.4	-2.2
Medication: Ventolin 100micrograms inhaler	2.3	3.0	8.7	-1.5	-1.6	-2.9	-1.3	-1.7	-1.7	-2.0	-1.6	-2.0	-1.7	-1.0	-1.6	-2.0	-1.4	0.8	-1.9	-0.7	-2.2
Hypertension (Self-reported)	2.3	6.3	15.0	2.0	3.0	3.9	2.4	2.2	2.3	3.1	2.7	2.4	1.4	2.7	2.5	2.8	2.4	-1.2	2.2	1.9	2.6
Number of self-reported non-cancer illnesses	2.3	4.1	12.4	-1.6	-1.6	-1.9	-1.8	-1.0	-2.3	-1.7	-1.7	-2.3	-2.4	-1.2	-1.9	-2.3	-3.5	1.5	-2.1	-2.1	-2.2
Pack years of smoking	2.3	3.4	11.6	-1.5	-1.9	-2.8	-1.9	-1.6	-1.7	-1.7	-2.0	-0.9	-1.5	-3.4	-1.6	-1.3	-2.6	0.9	-0.7	-1.8	-1.3
Blood Red Count	2.2	21.2	36.1	-5.2	-4.9	-4.5	-4.6	-4.0	-4.6	-5.1	-4.6	-3.9	-4.8	-3.4	-4.9	-4.6	-3.5	6.0	-4.8	-3.9	-4.9
Average weekly spirits intake	2.2	2.7	4.7	-1.4	-2.2	-1.8	-1.8	-1.5	-1.8	-2.1	-1.7	-1.7	-1.2	-0.8	-2.0	-1.7	-1.8	0.9	-1.6	-0.6	-1.9
Age at first live birth	2.2	3.9	7.6	2.8	2.0	1.2	1.9	1.9	2.2	1.8	2.3	1.7	2.4	0.8	2.3	1.2	1.9	-0.7	2.0	2.7	2.0
Neck or shoulder pain in last month	2.2	3.2	5.1	-1.2	-1.9	-0.7	-2.0	-1.7	-2.3	-1.6	-2.2	-2.2	-1.2	0.1	-2.2	-2.2	-2.3	1.6	-1.9	-1.4	-1.7
Illnesses of father: High blood pressure	2.2	2.7	5.4	1.2	1.9	2.1	1.3	1.3	1.1	2.1	1.5	1.6	1.6	2.3	1.5	1.9	0.8	-1.6	2.0	-0.2	2.2
Diastolic blood pressure, automated reading	2.2	6.7	15.3	1.6	2.7	3.5	2.3	2.0	2.6	2.8	2.3	2.8	1.5	3.1	2.2	3.3	3.9	-2.0	2.1	1.1	3.2
Mouth/teeth dental problems	2.1	3.3	5.7	1.8	1.8	1.2	1.8	1.1	1.6	1.8	1.7	1.9	1.1	2.2	1.8	2.2	2.4	-1.9	2.0	1.8	1.9
Leg fat percentage (right)	2.1	7.6	14.9	-3.0	-3.0	-3.9	-2.6	-3.2	-2.7	-3.2	-2.6	-2.2	-2.0	-3.3	-2.9	-2.5	-1.5	2.2	-3.0	-1.5	-2.9
Number of children fathered	2.1	2.4	4.5	-1.4	-1.7	-1.5	-1.4	-1.7	-1.5	-1.8	-1.8	-2.0	-1.5	-0.5	-1.6	-1.9	-0.7	1.0	-1.7	-0.9	-2.1
Illness, injury, bereavement, stress in last 2 years	2.1	2.6	4.7	1.9	1.7	1.1	1.7	1.2	1.9	1.8	1.6	1.5	2.2	1.9	1.7	1.7	1.6	-0.5	1.6	1.2	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.1	4.3	10.5	1.9	1.8	1.6	1.4	1.9	2.2	2.2	2.1	3.1	1.2	0.5	2.2	2.8	2.0	-1.3	3.2	1.2	2.6
Ulcerative Colitis (UC)	2.0	3.7	5.6	1.9	2.2	2.0	2.3	1.9	2.2	2.1	2.3	1.7	2.4	2.0	2.0	1.6	1.2	-1.6	1.5	1.7	1.8
High blood pressure	2.0	5.7	16.4	1.8	2.9	4.0	2.2	2.0	2.1	3.0	2.5	2.3	1.8	2.6	2.3	2.6	2.2	-1.1	1.9	1.8	2.4
Mouth/teeth dental problems: Loose teeth	2.0	2.4	7.0	-1.6	-1.4	-2.1	-1.1	-1.5	-1.4	-1.4	-1.3	-1.1	-1.1	-2.1	-1.2	-1.4	-2.6	1.4	-1.2	-1.3	-1.3
Hearing difficulty/problems: Yes	1.9	2.9	4.9	-1.6	-1.9	-0.7	-2.2	-1.5	-1.9	-1.8	-1.9	-1.7	-1.8	-0.5	-2.2	-1.7	-1.8	1.4	-1.9	-1.5	-1.8
Age when periods started (menarche)	1.9	4.5	9.1	-1.6	-2.5	-3.0	-2.4	-1.8	-2.3	-2.4	-2.6	-2.0	-2.0	-2.9	-2.3	-2.1	-1.8	0.3	-1.6	-0.5	-2.2
Frequency of tiredness / lethargy in last 2 weeks	1.9	3.2	9.2	-1.2	-1.7	-1.2	-1.2	-0.7	-1.4	-1.7	-1.7	-2.2	-1.7	-0.3	-1.9	-2.2	-3.0	1.4	-2.7	-0.8	-2.4
Deep venous thrombosis (DVT) (self-reported)	1.9	2.5	4.8	-1.8	-1.6	-2.2	-0.9	-0.9	-1.3	-1.9	-1.3	-1.6	-1.9	-0.7	-1.4	-1.7	-1.4	1.6	-1.9	-1.3	-1.9
Height	1.8	35.5	63.8	6.6	6.5	8.0	5.3	4.8	5.8	7.5	6.3	6.4	6.0	2.9	6.1	6.4	4.0	-4.2	6.7	4.2	7.2
Waist Hip Ratio (WHR)	1.8	8.0	18.4	-2.6	-3.1	-4.1	-2.0	-1.8	-2.5	-3.5	-3.2	-2.8	-1.4	-3.2	-2.6	-2.8	-4.3	0.4	-3.0	-1.6	-3.1
Number of treatments/medications taken	1.8	3.2	8.0	-1.7	-1.3	-0.9	-1.5	-1.6	-1.9	-1.2	-1.8	-2.0	-2.4	0.1	-1.9	-1.9	-2.8	0.9	-2.0	-2.4	-1.9
Arm fat percentage (right)	1.8	7.0	11.8	-2.9	-2.8	-3.0	-2.3	-2.9	-2.7	-3.2	-2.4	-2.6	-2.3	-2.1	-2.9	-2.7	-1.8	2.2	-3.4	-1.2	-3.2
Age at last live birth	1.8	2.6	7.0	2.0	1.5	1.7	1.4	1.4	1.4	1.4	1.7	1.2	1.8	1.0	1.7	1.1	1.9	-0.6	1.8	2.6	1.7
Mean Putamen Volume	1.7	1.9	2.8	-1.4	-1.5	-0.9	-1.4	-1.6	-1.6	-1.6	-1.5	-1.5	-1.7	-0.5	-1.5	-1.2	-1.1	1.0	-1.4	-1.4	-1.4
HDL Cholesterol	1.7	2.9	5.4	1.6	1.8	0.7	1.8	1.8	1.8	1.9	1.9	2.1	1.3	-0.2	2.0	2.1	0.2	-2.3	2.0	1.3	1.9
Blood White Count	1.7	12.9	17.1	-3.4	-3.8	-2.2	-4.0	-3.2	-3.9	-3.4	-3.9	-4.0	-3.6	-1.1	-4.1	-4.1	-3.7	3.8	-3.8	-3.5	-4.0
Hypothyroidism (self reported)	1.7	4.0	8.6	-1.6	-2.1	-0.1	-2.3	-1.1	-1.8	-2.0	-1.9	-2.6	-1.6	-1.5	-2.4	-2.2	-2.9	1.5	-2.6	-1.2	-2.4
Medication: Blood pressure	1.7	2.9	8.6	1.2	2.2	2.9	2.0	1.7	1.3	2.3	2.0	1.3	0.5	2.3	1.6	1.8	1.6	-0.7	1.0	0.6	1.6
Arm fat percentage (left)	1.7	6.7	11.6	-2.7	-2.7	-3.0	-2.3	-2.8	-2.5	-3.1	-2.3	-2.5	-2.1	-2.3	-2.9	-2.7	-1.7	2.2	-3.4	-1.1	-3.2
Average weekly red wine intake	1.7	2.5	8.2	1.8	1.3	2.9	1.2	1.7	1.6	1.3	1.3	0.7	2.1	2.2	1.2	0.8	1.6	-1.1	0.8	2.1	0.8
Back pain experienced in last month	1.7	2.5	6.3	-1.3	-1.8	-2.0	-1.5	-1.5	-1.3	-2.0	-1.9	-1.4	-2.5	-1.8	-1.6	-1.5	-0.6	1.1	-1.7	-0.6	-1.7
Leg fat percentage (left)	1.7	6.1	15.8	-2.6	-2.6	-4.0	-2.0	-2.5	-2.3	-2.9	-2.2	-1.9	-1.7	-3.6	-2.5	-2.2	-1.8	1.6	-2.7	-1.2	-2.6
Triglycerides	1.6	2.7	3.8	-1.1	-1.8	-0.9	-1.8	-1.8	-1.9	-1.6	-1.9	-1.6	-1.7	-1.4	-1.9	-1.4	-1.6	1.9	-1.2	-1.8	-1.6
Medication: Paracetamol	1.6	2.7	8.1	-1.0	-1.8	-1.6	-1.3	-0.4	-1.0	-2.0	-1.7	-1.9	-1.1	-1.5	-1.5	-2.1	-2.8	1.6	-1.9	-0.8	-1.8
Schizophrenia vs Biploar Disorder	1.5	2.0	4.4	1.2	1.6	2.1	1.2	1.4	1.7	1.7	1.2	1.6	0.7	1.4	1.1	1.5	1.3	-1.9	0.7	1.2	1.3
Chronic bronchitis/emphysema (father)	1.5	1.7	4.2	-1.0	-1.1	-1.6	-0.9	-0.1	-0.9	-1.4	-1.1	-1.5	-0.5	-1.2	-1.2	-1.6	-2.1	1.3	-1.5	-1.2	-2.0
Body mass index (BMI)	1.5	6.4	11.5	-3.2	-2.6	-2.4	-2.4	-2.5	-2.6	-2.9	-2.2	-2.5	-2.4	-2.1	-2.9	-2.5	-1.6	2.2	-3.4	-1.5	-3.1
Waist circumference	1.5	5.4	9.8	-2.8	-2.3	-3.0	-2.0	-2.1	-2.2	-2.7	-2.0	-2.1	-2.1	-2.7	-2.4	-2.1	-1.9	1.3	-3.1	-1.0	-3.0
Asthma	1.5	2.9	6.0	-1.6	-1.4	-1.7	-1.1	-1.5	-1.9	-1.6	-1.1	-2.0	-1.1	-0.6	-1.5	-2.1	-2.4	1.9	-2.2	-1.3	-2.3
Medication for cholesterol, blood pressure or diabetes	1.5	2.5	6.7	-1.3	-2.2	-2.6	-1.9	-1.7	-1.2	-2.2	-1.6	-1.2	-0.5	-2.1	-1.4	-1.7	-0.7	1.2	-1.1	-0.2	-1.7
Medication for pain relief, constipation, heartburn	1.5	2.6	4.2	1.5	1.6	1.2	1.3	0.6	1.4	1.8	2.0	1.8	2.0	1.1	1.6	2.0	1.9	-1.0	2.0	1.2	1.9
Asthma (self-reported)	1.5	2.9	5.5	-1.5	-1.4	-2.0	-1.1	-1.4	-1.9	-1.7	-1.1	-2.0	-1.2	-0.9	-1.5	-2.1	-2.3	1.9	-2.2	-1.1	-2.3
Ever depressed for a whole week	1.5	1.9	6.7	-1.2	-1.5	-2.6	-1.2	-0.3	-0.8	-1.5	-1.4	-0.9	-2.2	-1.9	-1.1	-1.0	-1.0	0.5	-0.5	-1.4	-1.4
Coronary Artery Disease (CAD)	1.4	1.6	4.8	-1.8	-1.3	-0.6	-1.3	-1.0	-1.4	-1.4	-1.2	-1.3	-2.2	-0.5	-1.2	-1.6	-0.5	1.0	-1.4	-1.2	-1.0
Cardiovascular Disease	1.4	4.6	14.3	1.2	2.7	3.8	2.2	1.5	1.8	2.7	2.2	1.7	1.3	2.3	2.1	2.3	1.8	-1.6	1.8	1.6	2.5
Father’s age at death	1.4	1.8	3.1	1.5	1.4	1.7	1.3	1.5	1.2	1.5	1.5	1.2	1.5	0.6	1.5	1.3	1.4	-0.5	1.8	1.3	1.0
Loud music exposure frequency	1.4	1.6	3.6	0.9	1.1	0.0	1.1	1.4	1.3	1.0	0.8	1.5	1.5	-0.9	1.4	1.5	-0.3	-1.3	1.9	1.4	1.5
Body fat percentage	1.4	5.5	10.4	-2.4	-2.5	-3.2	-2.0	-2.5	-2.2	-2.8	-2.1	-2.0	-1.6	-3.0	-2.5	-2.2	-1.9	1.6	-2.8	-1.0	-2.7
Illnesses of siblings: Diabetes	1.4	1.8	3.4	-1.5	-1.4	-0.7	-1.5	-1.6	-1.3	-1.2	-1.5	-1.0	-1.8	-0.6	-1.6	-1.3	-1.6	0.6	-1.4	-1.2	-1.1
Loneliness, isolation	1.4	1.9	9.3	-1.4	-1.4	-1.0	-1.1	-0.4	-0.9	-1.4	-1.1	-1.0	-0.8	-1.7	-1.2	-1.4	-3.0	0.6	-1.6	-1.6	-1.3
Qualifications: nursing, teaching	1.4	2.1	8.1	1.7	1.5	2.8	0.9	0.8	1.1	2.0	1.2	1.0	1.2	2.0	1.1	1.3	1.5	-0.8	1.4	0.7	1.5
Worry (Nagel 2018)	1.3	2.8	8.2	2.0	1.4	0.7	1.9	2.1	1.6	1.3	1.3	1.0	2.9	-1.1	1.7	1.1	-1.7	-1.7	1.6	2.3	1.2
Ulcerative Colitis	1.3	1.8	4.1	1.4	1.5	1.6	1.6	2.0	1.6	1.6	1.4	0.9	1.6	1.9	1.2	0.7	-0.5	-1.1	0.6	1.1	1.1
Supplements: Glucosamine	1.3	1.7	4.3	-1.1	-1.5	-1.8	-1.7	-1.1	-1.0	-1.2	-1.2	-0.8	-0.4	-0.3	-1.5	-1.3	-1.2	2.1	-1.1	-1.8	-1.2
Had menopause	1.3	1.6	3.9	-1.0	-1.3	-0.9	-1.6	-2.0	-1.6	-1.4	-1.5	-1.4	-1.1	-1.3	-1.4	-1.3	-0.8	0.7	-1.3	-0.3	-1.1
Chronic bronchitis/emphysema (mother)	1.3	1.5	5.1	-1.1	-1.3	-2.3	-1.2	-1.2	-1.2	-1.4	-0.9	-0.8	-0.8	-2.2	-1.0	-0.9	-0.6	0.6	-1.0	-1.1	-0.9
Number of full sisters	1.3	1.6	2.6	-1.4	-1.4	-0.6	-1.4	-0.6	-1.3	-1.2	-1.6	-1.2	-1.3	-0.3	-1.6	-1.1	-1.1	1.2	-1.4	-1.4	-1.3
Supplements: Calcium	1.3	1.5	2.9	-0.9	-1.3	-0.8	-1.3	-1.7	-1.5	-1.1	-1.1	-1.5	-1.2	-0.8	-1.4	-1.4	-0.0	1.0	-1.6	-1.3	-1.0
Lung FEV1/FVC ratio	1.2	6.0	12.8	2.3	2.4	2.0	1.7	1.5	2.2	2.6	2.4	3.3	1.7	1.2	2.6	3.3	3.4	-1.1	3.6	1.5	3.1
Taking other prescription medications	1.2	1.9	5.4	-0.8	-1.0	-0.9	-0.9	-1.3	-1.7	-1.1	-1.0	-1.8	-1.5	-0.4	-1.2	-1.7	-2.3	1.4	-1.5	-1.4	-1.7
Hayfever/allergic rhinitis (self-reported)	1.2	1.5	3.2	1.7	1.4	0.9	1.4	1.0	1.4	1.3	1.5	1.0	-0.1	1.8	1.4	0.8	1.2	-0.2	1.1	1.4	1.0
Trunk predicted mass	1.2	6.8	14.6	1.7	3.1	3.8	2.3	1.8	2.0	3.4	3.2	2.9	1.2	1.9	2.6	3.0	2.8	-2.1	2.6	2.0	3.0
Birth weight of first child	1.2	2.1	7.3	0.4	1.4	2.7	0.9	1.2	1.5	1.4	0.8	1.7	0.9	2.1	1.0	1.8	1.0	-1.9	1.2	0.5	1.4
Exposure to tobacco smoke outside home	1.2	1.6	13.4	-0.6	-1.3	-3.7	-0.8	-0.6	-0.7	-1.3	-1.0	-0.7	0.4	-2.4	-0.7	-1.0	-0.3	0.1	-0.6	-0.2	-1.0
Worry too long after embarrassment	1.2	2.1	7.5	1.6	1.1	-0.0	1.5	1.8	1.6	1.0	0.9	1.5	2.7	-1.2	1.5	1.0	-0.8	-1.7	1.4	1.6	0.9
Fractured/broken bones in last 5 years	1.2	1.5	8.8	-0.9	-1.4	-3.0	-1.4	-0.1	-0.7	-1.1	-0.9	-0.7	-0.7	-1.8	-1.0	-1.1	-0.7	0.3	-0.8	-0.9	-1.4
Myopia	1.2	1.7	6.7	0.8	1.2	2.6	0.3	1.0	0.7	1.7	1.2	1.0	1.4	2.2	0.7	1.2	1.7	-0.5	1.0	0.6	1.5
Vascular/heart problems diagnosed by doctor	1.2	3.2	10.8	-1.2	-2.3	-3.3	-1.9	-1.7	-1.6	-2.3	-1.9	-1.6	-1.3	-1.9	-1.7	-1.9	-1.3	0.8	-1.2	-1.2	-1.8
Blood Platelet Count	1.1	12.4	18.7	-3.2	-3.3	-2.6	-4.1	-3.9	-4.3	-3.1	-3.8	-3.9	-4.0	-2.6	-3.8	-3.8	-3.8	2.4	-3.0	-3.9	-3.2
BMI	1.1	6.6	12.5	-3.5	-2.6	-2.6	-2.3	-2.3	-2.5	-3.0	-2.1	-2.5	-3.1	-2.0	-2.9	-2.5	-1.0	2.6	-3.4	-0.8	-3.0
Trunk fat-free mass	1.1	6.5	14.7	1.7	3.1	3.8	2.3	1.7	2.0	3.3	3.1	2.8	1.2	1.9	2.5	3.0	2.7	-2.1	2.5	2.0	2.9
Tense / ‘highly strung’	1.1	1.8	5.0	1.7	1.5	1.3	1.6	1.7	1.3	1.5	1.1	0.8	2.2	0.5	1.2	0.9	-1.1	-0.9	0.9	1.4	1.3
Guilty feelings	1.1	1.6	4.7	-1.3	-1.4	-1.3	-1.3	-0.5	-0.8	-1.3	-1.5	-1.1	-0.4	-0.3	-1.4	-1.4	-2.2	-0.2	-1.3	-1.0	-2.0
Medication: Blood pressure	1.1	2.1	4.4	1.2	1.8	2.1	1.4	1.2	1.6	2.1	1.6	1.7	1.1	0.8	1.4	1.7	0.9	-1.1	1.2	0.7	1.5
Number of operations (self-reported)	1.1	1.7	6.8	-1.4	-1.1	-0.6	-0.7	-0.7	-0.9	-1.3	-1.1	-1.6	-2.0	-0.1	-1.5	-1.5	-0.9	0.9	-2.6	-0.6	-1.5
Bipolar Disorder or Schizophrenia	1.0	2.4	6.7	0.8	1.1	-0.9	1.1	0.7	1.3	1.0	1.3	2.1	1.9	-1.8	1.8	2.3	1.0	-1.1	2.6	0.4	2.3
Neuroticism (Nagel 2018)	1.0	2.2	9.4	1.4	0.8	-0.8	1.2	1.6	1.2	0.7	0.7	0.8	3.1	-2.2	1.2	0.6	-2.9	-1.2	1.3	1.5	0.4
Neuroticism (2016)	1.0	1.4	3.5	-1.0	-1.3	-0.5	-1.2	-0.6	-1.1	-1.2	-1.8	-1.5	-0.2	-0.1	-1.4	-1.3	-1.9	0.3	-1.3	-0.6	-1.7
Tanning	1.0	11.7	20.7	-3.6	-3.8	-4.5	-3.3	-3.1	-3.1	-3.9	-3.3	-3.0	-3.1	-3.4	-3.5	-3.5	-2.9	2.3	-3.8	-2.8	-3.9
Angina	1.0	1.3	2.3	-1.2	-1.1	-1.0	-0.9	-0.7	-1.3	-1.0	-1.3	-1.5	-1.2	-0.4	-1.3	-1.4	-0.7	1.2	-1.3	-1.4	-1.2
Forced vital capacity (FVC)	1.0	3.7	9.7	2.0	1.7	2.9	1.2	1.3	1.7	2.4	1.9	2.1	1.3	1.3	1.8	2.1	1.3	-1.3	3.1	1.2	2.4
Ever unenthusiastic/disinterested for a whole week	1.0	1.3	3.5	1.2	1.0	0.3	1.1	1.9	1.3	1.1	1.1	1.3	0.3	0.1	1.2	1.2	-0.5	-1.7	1.3	0.5	1.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.0	1.5	4.0	-0.7	-1.1	-1.7	-0.5	-0.3	-1.1	-1.4	-1.0	-1.9	-0.5	-1.2	-1.0	-1.9	-1.2	-0.0	-1.5	0.0	-2.0
Ever highly irritable/argumentative for 2 days	1.0	1.2	4.3	-1.0	-1.2	-1.5	-1.2	0.0	-0.7	-0.9	-1.3	-0.7	-2.1	-0.3	-1.1	-0.8	-0.9	0.6	-1.0	-1.6	-1.0
Major Depression (MDD)	0.9	1.1	3.5	-1.4	-1.1	-1.6	-1.2	-0.8	-0.5	-1.2	-1.4	-0.4	-0.5	-1.9	-0.9	-0.4	-0.9	-0.3	0.2	-1.6	-0.5
Trunk fat percentage	0.9	3.7	7.1	-1.9	-2.0	-2.5	-1.8	-2.1	-1.8	-2.2	-1.8	-1.6	-1.2	-2.7	-2.1	-1.7	-1.6	1.1	-2.3	-0.9	-2.2
Medication: Levothyroxine sodium	0.9	1.6	2.8	-1.5	-1.4	-0.3	-1.5	-0.4	-1.0	-1.4	-1.1	-1.1	-1.4	-0.2	-1.4	-1.2	-1.7	1.7	-1.6	-0.6	-1.6
High blood pressure (mother)	0.9	1.3	7.3	0.8	1.3	2.7	1.1	0.8	1.1	1.3	1.2	0.8	-0.2	1.3	1.0	0.8	0.8	-0.1	0.0	0.7	1.2
Number of live births	0.9	1.3	6.1	-1.0	-1.3	-0.4	-1.2	0.0	-0.9	-1.4	-0.9	-1.0	-0.6	-2.5	-1.0	-1.1	-1.5	0.3	-1.2	0.8	-1.4
Qualifications: A levels/AS levels or equivalent	0.9	1.9	6.8	1.2	1.4	2.6	0.7	0.6	0.8	1.7	1.5	0.9	1.3	1.9	1.1	1.1	1.9	-0.9	1.0	1.5	1.2
Angina (self-reported)	0.9	1.2	2.1	-1.1	-1.0	-0.9	-0.8	-0.7	-1.2	-0.9	-1.2	-1.5	-1.1	-0.3	-1.2	-1.3	-0.7	1.2	-1.3	-1.5	-1.0
Leg fat mass (right)	0.9	3.5	5.4	-2.3	-2.0	-2.2	-1.7	-2.3	-2.0	-2.1	-1.6	-1.4	-1.7	-2.3	-2.1	-1.6	-0.8	1.4	-2.3	-0.8	-2.1
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.0	2.2	-1.4	-1.1	-0.5	-1.0	-1.5	-1.3	-0.7	-1.5	-0.6	-1.3	0.2	-1.3	-0.7	0.4	0.7	-1.0	-1.4	-0.4
High cholesterol (Self-reported)	0.9	1.5	4.1	1.0	1.4	0.6	1.4	1.2	1.0	1.2	1.2	1.2	2.0	-0.7	1.4	1.4	-0.4	-1.5	1.1	0.8	1.6
Commuting to job workplace: Cycle	0.9	1.1	2.0	1.1	1.1	1.1	0.6	1.1	1.0	1.2	1.1	1.3	1.2	0.6	1.1	1.0	1.4	-0.6	1.1	1.2	0.7
Depression (Nagel 2018)	0.8	1.2	3.9	-0.8	-1.3	-1.1	-1.0	-0.7	-0.7	-1.2	-1.3	-1.1	-0.9	-0.9	-1.3	-1.1	-2.0	0.5	-0.9	-0.7	-1.2
Had other major operations	0.8	1.0	2.0	-0.8	-1.0	-1.0	-0.7	-0.4	-0.9	-1.2	-1.1	-1.1	-1.1	-1.3	-1.0	-1.1	-0.5	0.7	-1.2	-1.0	-1.4
Medication: Lansoprazole	0.8	0.9	1.7	-1.2	-0.8	-1.3	-0.4	-0.7	-0.9	-1.0	-1.1	-1.1	-0.6	0.5	-0.8	-1.2	-0.6	0.0	-1.2	-1.3	-1.2
Birth weight	0.8	1.8	5.6	1.0	1.2	2.4	0.9	0.5	0.8	1.7	0.9	1.3	0.9	1.6	1.0	1.5	1.6	-1.1	1.6	1.3	1.6
Forced vital capacity (FVC), Best measure	0.8	2.9	7.7	1.7	1.6	2.5	1.2	1.1	1.4	2.1	1.7	2.1	0.8	1.1	1.7	2.0	1.3	-1.0	2.8	1.0	2.3
Chest pain or discomfort	0.8	1.1	2.0	-0.8	-1.0	-0.6	-0.9	-0.7	-0.9	-0.8	-1.2	-1.1	-0.7	-0.8	-1.1	-1.2	-1.4	1.3	-1.4	-1.4	-1.0
Whole body fat-free mass	0.8	4.4	12.7	1.1	2.6	3.6	1.9	1.4	1.6	2.7	2.7	2.2	0.9	1.6	2.0	2.4	2.1	-1.7	1.7	1.7	2.2
Whole body water mass	0.8	4.3	12.4	1.1	2.5	3.5	1.9	1.4	1.6	2.7	2.7	2.2	0.8	1.6	2.0	2.4	2.2	-1.7	1.6	1.6	2.2
Ever taken oral contraceptive pill	0.8	0.9	1.7	-1.1	-1.1	-0.7	-1.1	-0.4	-0.9	-1.0	-0.7	-1.1	0.2	-1.0	-1.2	-1.1	-1.3	0.6	-0.9	-0.8	-0.9
Irritable Bowel Disease (IBD)	0.7	1.7	3.5	1.5	1.4	1.0	1.6	1.3	1.3	1.2	1.6	0.9	1.9	0.9	1.5	0.9	0.4	-1.1	0.9	1.9	1.0
Qualifications: CSEs or equivalent	0.7	1.0	3.7	-0.0	1.0	0.8	1.4	1.2	0.9	0.9	1.2	0.9	-0.3	0.8	0.8	1.1	1.3	-0.6	-0.4	1.9	0.5
Hypothyroidism/myxoedema (self-reported)	0.7	1.4	3.5	-1.1	-1.1	0.4	-1.2	-0.4	-0.9	-1.2	-0.9	-1.4	-1.0	-0.5	-1.3	-1.3	-1.8	1.0	-1.9	-0.4	-1.6
Arm fat-free mass (right)	0.7	3.5	8.0	1.2	2.2	2.8	1.7	1.5	1.6	2.4	2.3	2.1	0.9	0.8	1.8	2.3	1.8	-1.7	1.7	1.5	2.1
Comparative body size at age 10	0.7	2.0	3.6	-1.6	-1.4	-1.2	-1.3	-1.9	-1.4	-1.7	-1.3	-1.4	-1.6	-1.8	-1.4	-1.4	0.2	1.3	-1.1	-1.1	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	0.9	2.9	-1.1	-0.7	-1.5	-0.5	-0.7	-0.7	-0.9	-0.9	-0.9	-1.0	-1.7	-0.8	-0.9	0.3	-0.5	-1.3	-0.1	-1.1
Smoking status: Previous	0.7	1.0	3.6	-0.3	-0.8	-1.9	-0.8	-0.2	-0.7	-0.7	-1.3	-0.7	-0.8	-1.5	-0.8	-0.8	-1.5	-1.2	-0.3	-0.8	-0.8
Ever had bowel cancer screening	0.7	0.8	1.5	-1.2	-0.6	0.6	-1.0	-0.3	-1.2	-0.9	-1.1	-1.1	-1.0	0.3	-1.0	-0.8	-0.8	0.7	-1.1	-0.8	-0.7
Mineral and other dietary supplements	0.7	0.9	2.3	1.0	0.7	1.0	0.9	1.4	1.3	0.8	0.9	0.9	0.8	-0.9	1.1	0.6	-0.5	-0.7	0.8	1.5	0.4
Breast cancer (self-reported)	0.7	0.8	4.4	1.3	0.8	-0.3	1.1	0.8	0.8	0.4	1.1	0.8	0.4	-0.4	1.0	0.7	-0.5	-0.6	0.7	2.1	0.5
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.7	0.7	0.5	0.4	0.4	0.5	0.9	0.9	0.5	1.2	0.3	1.4	0.7	1.1	1.5	-0.2	1.6	0.7	0.9
Medication: Bendroflumethiazide	0.7	1.0	2.0	1.1	1.3	1.4	1.1	0.3	0.7	1.4	1.3	0.9	1.1	1.2	1.0	1.1	-0.1	-0.6	0.8	0.2	1.0
Alcohol drinker status: Never	0.7	0.8	3.2	-1.2	-0.9	-0.9	-1.2	-0.8	-0.8	-0.8	-1.0	-0.5	-1.4	-0.1	-0.9	-0.6	0.1	0.7	-0.4	-1.8	-0.8
Average weekly beer plus cider intake	0.7	1.0	4.4	-1.1	-1.0	-0.9	-1.1	0.0	-0.6	-1.1	-1.0	-0.6	-0.8	-1.6	-0.9	-0.4	-2.1	0.0	-0.8	-0.7	-1.0
Leg fat mass (left)	0.7	2.9	6.1	-2.1	-1.7	-2.2	-1.4	-1.9	-1.7	-1.9	-1.4	-1.2	-1.5	-2.5	-1.8	-1.4	-1.0	1.1	-2.1	-0.5	-1.9
Arm predicted mass (left)	0.7	3.6	7.8	1.1	2.2	2.8	1.8	1.4	1.5	2.4	2.5	2.2	0.9	0.8	1.9	2.3	1.9	-1.7	1.6	1.7	2.0
Bipolar Disorder (2018)	0.6	0.9	4.6	-1.0	-0.9	-2.1	-0.9	-1.2	-1.0	-0.9	-0.8	-0.4	-0.4	-1.3	-0.6	-0.3	0.2	1.3	0.1	-1.0	-0.1
Lupus	0.6	0.9	2.2	-0.2	-0.9	-1.5	-1.3	-0.8	-1.1	-0.6	-1.2	-0.4	-1.1	-0.4	-1.0	-0.8	-1.5	-0.0	-0.6	-0.7	-0.8
Neuroticism	0.6	1.3	13.8	0.2	0.1	-0.7	0.3	1.0	0.2	0.0	-0.1	0.1	1.5	-2.4	0.3	-0.1	-3.7	-0.8	0.2	0.5	-0.1
Hearing difficulty/problems with background noise	0.6	0.9	2.4	-0.6	-0.9	-1.3	-0.8	0.0	-0.6	-1.2	-0.9	-1.0	-1.3	-1.1	-0.8	-1.0	-1.5	0.4	-0.9	-0.0	-1.1
Allergy	0.6	1.5	5.1	0.5	0.7	1.8	0.0	0.1	0.5	0.9	0.2	1.4	0.7	1.1	0.4	1.7	2.3	-2.1	1.2	0.6	1.8
Neuroticism score	0.6	1.2	12.1	0.4	0.3	-0.0	0.7	1.4	0.7	0.2	0.1	0.1	1.6	-0.9	0.4	-0.1	-3.5	-1.2	0.0	0.9	-0.1
Alcohol intake versus 10 years previously	0.6	0.8	2.7	1.0	0.8	1.1	0.2	0.6	1.0	1.2	0.7	1.3	0.6	0.2	0.7	1.0	-0.4	-1.6	1.1	0.2	1.1
Prospective memory result	0.6	0.8	1.6	0.9	0.9	-0.7	1.3	1.1	0.9	0.9	1.2	1.0	0.8	0.4	1.1	0.9	0.4	-1.0	0.4	-0.1	0.4
Arm fat mass (right)	0.6	2.6	5.6	-2.0	-1.6	-1.4	-1.4	-1.9	-1.7	-1.8	-1.2	-1.5	-1.6	-1.4	-1.9	-1.5	-0.7	1.4	-2.4	-0.5	-2.0
Heart disease (mother)	0.6	0.7	4.2	-0.2	-0.9	-2.0	-0.5	-0.5	-0.7	-0.9	-0.8	-0.6	-0.3	-0.9	-0.5	-0.7	-1.4	0.7	-0.3	-0.3	-0.9
Whole body fat mass	0.6	2.5	4.1	-1.9	-1.6	-1.6	-1.4	-2.0	-1.7	-1.8	-1.3	-1.3	-1.4	-1.9	-1.8	-1.4	-0.9	1.1	-2.0	-0.6	-2.0
Arm predicted mass (right)	0.6	3.1	7.4	1.1	2.1	2.7	1.5	1.4	1.4	2.3	2.3	2.0	0.8	0.3	1.7	2.1	1.6	-1.7	1.6	1.4	1.9
Handedness (chirality/laterality): Left-handed	0.6	0.8	1.8	-1.0	-0.9	-0.1	-0.8	-1.4	-0.7	-0.7	-1.1	-0.8	-0.9	0.1	-1.1	-1.0	-0.9	0.5	-0.7	-0.8	-1.0
Diabetes diagnosed by doctor	0.6	0.9	2.8	-1.5	-0.9	0.2	-1.0	-0.6	-1.1	-1.0	-1.0	-1.1	-1.7	-0.2	-1.2	-0.9	-0.2	0.2	-1.6	-0.3	-0.9
Medication: Paracetamol	0.6	0.9	4.0	-0.3	-0.8	-1.4	-0.3	0.4	-0.2	-1.0	-0.7	-0.8	-1.0	-1.0	-0.6	-1.0	-2.0	1.1	-0.9	-0.5	-0.9
Arm fat-free mass (left)	0.6	3.0	7.8	1.0	2.1	2.8	1.6	1.3	1.3	2.2	2.3	2.0	0.6	0.7	1.7	2.1	1.8	-1.4	1.5	1.5	1.8
Depressed Affect (Nagel 2018)	0.5	1.0	10.2	0.4	0.0	-0.7	0.0	0.5	0.3	0.1	-0.0	0.1	1.6	-1.9	0.2	-0.1	-3.2	0.2	0.3	0.5	-0.1
Intelligence (Savage-Jansen 2018)	0.5	1.6	4.0	-1.8	-0.6	0.6	-0.7	-1.2	-0.9	-0.9	-0.5	-1.9	-1.5	1.4	-1.1	-1.6	-0.3	1.2	-2.0	-1.0	-1.8
Alzheimer’s Disease (in father)	0.5	0.5	2.4	0.2	0.2	0.8	0.2	0.4	0.5	0.3	0.4	0.3	1.6	0.9	0.2	0.4	1.2	-0.9	0.3	1.2	0.1
Primary Biliary Cirrhosis	0.5	0.7	4.3	-0.5	-0.4	-1.6	-0.5	-0.5	-0.6	-0.5	-0.5	0.1	-1.1	-0.3	-0.1	-0.0	-2.1	0.2	1.1	-1.1	-0.1
Type 2 Diabetes (T2D) (2018)	0.5	0.9	2.2	-1.4	-0.9	-0.0	-1.0	-1.2	-1.4	-0.9	-0.8	-0.9	-1.5	0.0	-1.1	-0.6	0.5	0.2	-1.2	-0.4	-0.6
Frequency of depressed mood in last 2 weeks	0.5	0.7	5.7	-0.2	-0.8	0.0	-0.5	0.2	-0.3	-0.6	-0.8	-1.0	-0.6	0.0	-0.8	-0.9	-2.4	-0.5	-0.8	0.4	-0.9
Medication: Metformin	0.5	0.7	1.7	0.2	0.7	1.2	0.5	1.2	0.7	0.7	0.6	0.9	0.4	0.3	0.6	0.9	1.1	-1.0	0.5	1.3	0.8
Diabetes (father)	0.5	0.6	2.7	0.0	0.4	1.6	-0.4	0.3	-0.2	0.8	-0.0	-0.2	0.4	1.6	-0.3	-0.0	-1.5	-0.5	0.2	-1.1	0.5
Diabetes (mother)	0.5	0.6	2.4	0.1	-0.4	1.0	-0.0	0.1	-0.5	-0.4	-0.0	-1.0	1.1	-0.6	-0.5	-1.0	-1.5	1.3	-1.0	-0.3	-0.1
Relative age voice broke	0.5	0.7	4.8	0.0	-0.6	-2.2	-0.2	-0.4	-0.1	-0.6	-0.4	-0.5	0.6	-2.2	-0.2	-0.7	-0.2	-0.2	-0.2	-0.0	-0.8
Hayfever, allergic rhinitis or eczema	0.5	1.0	2.4	1.6	1.0	-0.3	1.3	1.4	1.4	1.0	1.4	0.4	1.0	-0.7	1.3	0.2	-0.6	0.8	1.0	0.5	0.3
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.7	-0.3	-0.7	0.7	-0.6	-0.1	-0.5	-0.4	-0.8	-0.7	-0.3	1.4	-0.7	-0.3	-1.6	1.2	-0.3	0.0	-0.5
Impedance of leg (left)	0.5	2.2	6.4	2.1	0.6	-1.5	1.2	1.2	1.3	0.7	0.4	1.6	2.3	-1.3	1.5	1.3	-0.2	-2.0	2.5	1.0	1.7
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	5.2	-0.3	-0.6	-0.4	-0.6	0.1	-0.2	-0.6	-0.8	-1.1	-0.9	-0.4	-0.8	-1.1	-2.3	-0.6	-1.2	-0.1	-1.2
Medication: Simvastatin	0.5	0.7	2.1	0.5	0.8	0.4	0.9	0.9	0.5	0.6	0.6	0.8	1.2	0.1	0.9	0.9	-0.9	-1.5	0.8	0.5	0.7
Breastfed as a baby	0.5	0.6	1.3	-0.6	-0.8	0.9	-0.8	-0.5	-0.5	-0.5	-1.2	-0.8	-1.1	0.4	-1.1	-0.8	0.1	0.6	-1.0	-0.3	-0.6
Headache pain in last month	0.5	0.8	3.6	1.2	0.9	1.9	1.0	0.8	0.9	0.9	0.4	0.7	0.5	0.5	0.9	0.5	-0.5	-0.9	0.7	0.7	1.0
High blood pressure (siblings)	0.5	0.7	1.6	0.0	1.3	1.1	0.8	1.0	0.8	1.3	0.9	1.0	0.2	0.4	0.8	1.1	-0.2	-1.0	0.6	-0.2	1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.3	1.5	0.7	0.8	0.8	1.0	0.9	0.8	0.7	0.3	1.3	0.9	0.7	0.0	0.1	-0.4	0.7	0.3	0.5
Suffer from ‘nerves’	0.5	0.8	4.6	0.2	-0.1	-0.4	0.1	0.9	0.0	-0.3	0.1	-0.5	1.4	-2.1	0.1	-0.7	-2.1	-0.9	-0.3	1.1	-0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	2.3	-0.7	-0.6	-1.5	-0.5	-0.9	-0.7	-0.7	-0.4	-0.5	-0.7	-1.5	-0.3	-0.6	-0.1	0.4	0.0	-0.7	-0.5
Arm fat mass (left)	0.5	2.1	4.5	-1.7	-1.4	-1.4	-1.3	-1.7	-1.5	-1.6	-1.0	-1.3	-1.3	-1.6	-1.7	-1.4	-0.7	1.3	-2.1	-0.5	-1.9
Miserableness	0.5	0.8	8.5	0.2	-0.2	-0.8	-0.1	0.7	0.1	-0.1	-0.0	-0.3	1.2	-1.7	0.0	-0.5	-2.9	0.1	-0.1	0.0	-0.4
Wears glasses or contact lenses	0.5	0.6	4.1	0.9	0.7	1.7	0.2	0.4	0.3	0.8	0.4	0.1	0.2	2.0	0.2	0.4	0.5	-0.2	0.5	-0.6	0.5
Hearing aid user	0.5	0.6	1.6	0.7	0.8	0.2	0.9	1.3	1.1	0.9	0.7	0.4	0.3	0.7	0.5	0.6	-1.1	-1.3	-0.0	0.9	0.5
Basal metabolic rate	0.5	2.7	8.3	0.7	2.0	2.9	1.4	0.9	1.2	2.1	2.2	1.8	0.6	1.1	1.5	2.0	1.8	-1.3	1.2	1.4	1.7
Ovarian Cancer	0.4	0.5	1.3	-0.5	-0.7	-0.4	-1.1	-0.7	-0.8	-0.6	-0.7	-1.1	0.4	-0.2	-0.8	-1.1	0.6	0.5	-0.8	-0.3	-1.1
Chronotype (morning person)	0.4	0.9	5.8	0.5	0.9	0.7	0.8	1.0	0.9	1.0	0.8	1.0	-0.8	2.4	0.7	1.0	1.0	0.4	0.3	0.4	0.7
Relative age of first facial hair	0.4	0.8	5.9	-0.1	-0.7	-2.4	-0.2	-1.1	-0.4	-0.7	-0.5	-0.3	0.3	-1.8	-0.1	-0.6	-0.7	-0.3	-0.2	-0.9	-0.7
Fed-up feelings	0.4	0.7	3.6	1.0	0.4	-0.5	0.7	1.2	0.8	0.5	0.6	0.6	1.0	-0.5	0.8	0.2	-1.9	-0.4	0.8	1.2	0.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.9	-0.6	-0.5	-0.0	-0.6	-0.5	-0.2	-0.1	-0.8	-0.4	-0.7	1.0	-0.8	-0.3	1.2	0.3	-0.8	-1.4	0.1
Nervous feelings	0.4	0.7	6.5	0.1	-0.1	-0.9	0.5	0.7	-0.1	-0.4	-0.2	-0.6	0.8	-1.5	0.2	-0.5	-2.5	-0.2	-0.2	1.0	-0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.4	0.8	2.4	0.1	0.4	1.5	0.1	0.8	0.7	0.6	0.4	1.3	0.6	0.9	0.4	1.1	1.5	-0.9	0.7	1.4	0.8
Noisy workplace	0.4	0.5	1.9	-0.7	-0.4	-1.4	-0.6	-0.3	-0.9	-0.4	-0.7	-0.5	-1.0	0.3	-0.6	-0.6	-0.9	0.6	-0.6	-0.9	-0.5
Exposure to tobacco smoke at home	0.4	0.4	1.3	-1.0	-0.4	-0.8	-0.5	-0.0	-0.7	-0.6	-0.5	-0.4	-0.9	0.3	-0.5	-0.3	-1.0	-0.2	-0.4	-1.1	-0.8
Medication: Aspirin	0.4	0.6	1.6	-0.9	-0.4	0.1	-0.5	-0.2	-1.0	-0.6	-0.9	-0.9	-0.8	-1.3	-0.6	-0.8	-1.1	-0.4	-0.7	-0.9	-0.6
Leg fat-free mass (right)	0.4	2.0	7.9	0.5	1.9	2.8	1.3	0.8	1.1	1.9	2.0	1.4	0.5	1.0	1.2	1.6	1.3	-1.2	0.6	1.2	1.2
Mood swings	0.4	0.8	7.6	0.3	-0.1	0.0	0.2	0.8	0.4	0.1	-0.1	-0.1	1.8	-0.5	-0.0	-0.0	-2.8	-0.2	-0.1	1.2	-0.1
Friendships satisfaction	0.4	0.5	1.0	-1.0	-1.0	-1.0	-0.4	-0.5	0.1	-0.7	-0.4	0.1	-1.0	-0.8	-0.6	-0.5	0.2	1.0	-0.7	-0.4	-0.5
Eye problems/disorders: Cataract	0.4	0.5	4.0	0.5	0.0	0.4	0.5	0.2	0.6	0.2	0.4	0.4	2.0	0.5	0.3	0.5	0.7	-1.0	0.5	0.9	0.4
Illnesses of father: None of the above (group 1)	0.4	0.5	1.9	-0.5	-1.1	-0.9	-0.8	-1.0	-0.7	-1.0	-0.9	-0.1	-0.5	-1.4	-0.6	-0.4	-0.4	0.4	-0.3	0.5	-0.4
Commuting to job workplace: Public transport	0.4	0.5	2.3	0.6	0.5	1.5	0.1	0.1	0.2	0.8	0.3	0.2	0.9	1.5	0.1	0.5	-0.9	-0.3	0.7	-0.3	0.5
Cholesterol lowering medication	0.4	0.6	2.0	0.0	0.8	-0.0	0.9	0.4	0.4	0.6	0.8	0.9	1.4	-1.1	0.9	0.8	-0.4	-0.4	0.9	0.7	1.0
Alcohol drinker status: Previous	0.4	0.4	2.2	0.0	-0.6	-0.6	-1.0	-0.9	-0.7	-0.2	-0.7	-0.4	-0.0	0.3	-0.8	-0.6	-0.8	0.0	-0.4	-1.5	-0.3
Alzheimer’s Disease (in mother)	0.3	0.3	1.6	-0.4	-0.2	1.3	-0.4	-0.2	-0.3	-0.0	-0.4	-0.6	0.4	0.8	-0.4	-0.4	-0.8	-0.5	-0.3	-0.6	-0.4
HbA1C	0.3	0.3	1.0	-0.4	-0.8	-0.6	0.1	-0.8	-0.6	-1.0	-0.4	-0.5	0.1	-0.8	-0.7	-0.4	-1.0	0.4	-0.1	0.0	-0.3
Ever had hysterectomy (womb removed)	0.3	0.3	1.9	-0.2	-0.2	-0.9	-0.3	-0.5	-0.8	-0.4	-0.2	-0.3	-0.1	-1.4	-0.3	-0.1	-0.3	0.7	-0.1	-0.6	-0.2
Severe depression (siblings)	0.3	0.3	1.0	-0.3	-0.5	-0.4	-0.3	0.0	0.1	-0.5	-0.6	-0.3	-0.8	0.4	-0.7	-0.4	-1.0	-0.6	-0.8	0.3	-0.7
Impedance of leg (right)	0.3	1.4	5.3	1.8	0.3	-1.1	0.7	0.7	1.0	0.5	0.1	1.4	1.8	-0.7	1.1	1.1	0.4	-1.3	2.3	0.9	1.5
Leg fat-free mass (left)	0.3	1.6	7.7	0.3	1.6	2.8	1.0	0.5	0.8	1.7	1.8	1.2	0.2	1.1	0.9	1.4	1.6	-0.9	0.3	1.2	1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.6	2.2	-1.5	-1.1	0.5	-1.3	-0.7	-0.8	-0.9	-1.1	-0.3	-0.3	0.3	-1.2	-0.4	0.3	0.1	-0.8	-0.0	-0.8
Stomach or abdominal pain in last month	0.3	0.3	1.1	-0.4	-0.2	-0.2	-0.4	-0.4	-0.5	-0.2	-0.5	-0.4	-1.0	0.8	-0.7	-0.4	1.1	1.0	-0.5	-0.5	-0.3
Leg predicted mass (left)	0.3	1.7	7.9	0.3	1.6	2.8	1.0	0.6	0.9	1.7	1.8	1.3	0.2	1.2	1.0	1.4	1.6	-1.0	0.4	1.2	1.0
Trunk fat mass	0.3	1.5	3.2	-1.4	-1.2	-1.3	-1.2	-1.7	-1.3	-1.3	-0.9	-0.8	-0.9	-1.8	-1.4	-0.9	-0.7	0.7	-1.6	-0.5	-1.4
Number of incorrect matches in round	0.3	0.5	2.0	-0.5	-0.7	-1.2	-0.8	-0.6	-0.3	-0.4	-1.0	0.6	-0.5	-1.4	-0.4	0.5	0.4	-0.0	0.7	0.1	0.1
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	1.7	-1.3	-0.5	0.8	-0.7	-0.0	-0.4	-0.5	-0.6	-0.2	-0.5	-0.0	-0.7	-0.1	-0.4	-1.2	-0.5	-0.5	-0.4
Medication: Cholesterol lowering	0.3	0.4	1.6	0.2	0.8	0.8	0.7	0.8	0.1	0.7	0.2	0.6	0.1	0.7	0.4	0.8	-0.8	-1.3	0.4	-0.8	0.7
Gout (self-reported)	0.3	0.5	3.2	-0.2	0.1	-0.5	0.3	-0.2	0.1	0.1	0.3	0.5	1.8	-1.5	0.2	0.6	0.4	-1.1	0.3	-0.2	0.5
Shortness of breath walking on level ground	0.3	0.4	1.7	-0.5	-0.2	-1.3	0.2	-0.5	-0.3	-0.4	0.1	-0.4	-1.0	-0.7	-0.3	-0.4	-0.7	0.7	-0.9	-0.1	-0.8
Medication: Allopurinol	0.3	0.4	2.4	-0.2	-0.0	-1.0	0.4	-0.3	0.1	-0.3	0.1	0.0	1.5	-1.3	0.2	0.1	-0.2	-1.0	-0.2	0.2	-0.0
Family relationship satisfaction	0.3	0.4	1.4	-0.5	-1.2	-0.9	-0.7	-0.1	-0.2	-1.1	-0.6	-0.4	-1.0	-0.3	-0.7	-0.6	-0.7	0.5	-0.1	0.3	-0.4
Illnesses of father: Heart disease	0.3	0.4	1.0	0.9	0.9	0.6	0.8	1.0	0.7	0.8	1.0	0.1	0.1	0.0	0.7	0.4	0.4	0.6	0.2	-0.2	0.4
Medication for cholesterol	0.3	0.4	1.5	1.2	0.5	-0.1	0.8	0.7	0.7	0.2	0.7	0.3	0.6	0.9	0.8	0.3	0.5	0.2	0.6	0.7	0.4
Leg predicted mass (right)	0.3	1.7	7.4	0.3	1.7	2.7	1.2	0.7	0.9	1.8	1.9	1.2	0.3	0.9	1.1	1.4	1.2	-1.2	0.4	1.1	1.1
Supplements: Fish oil (including cod liver oil)	0.3	0.4	2.3	-0.7	-0.1	-0.5	-0.3	-1.1	-0.8	-0.2	-0.3	0.1	-0.1	1.0	-0.4	0.3	1.5	0.2	0.1	-0.5	0.5
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.1	0.8	0.6	0.6	0.2	-0.0	0.1	0.7	0.3	-0.0	0.1	1.0	0.3	0.4	-0.0	0.1	0.8	-0.9	1.1
Alzheimer’s Disease (including proxy)	0.2	0.3	1.8	-0.1	-0.1	1.2	-0.3	-0.1	-0.1	0.0	-0.2	-0.0	1.4	1.0	-0.0	0.3	0.1	-1.0	0.6	0.0	0.0
Verbal and Numeric Reasoning (VNR)	0.2	0.5	3.5	-0.4	0.7	1.4	0.6	0.0	0.4	0.5	0.7	-0.1	-0.2	1.9	0.1	0.2	-0.1	0.6	-0.4	-1.3	0.0
Breast Cancer	0.2	0.4	0.9	-1.0	-0.7	-0.1	-0.5	-0.7	-0.6	-0.6	-0.9	-0.6	-0.9	-0.3	-0.7	-0.7	0.3	-0.2	-0.7	0.1	-0.8
Body Mass Index (BMI) (2010)	0.2	0.3	0.9	0.3	0.1	0.7	0.3	0.9	0.7	0.1	0.3	0.6	0.4	-0.6	0.3	0.4	-0.1	-0.8	0.5	0.6	0.5
Crohns Disease (2012)	0.2	0.4	2.3	0.6	0.4	-0.8	0.7	-0.0	0.1	0.0	0.7	0.2	0.4	-0.2	0.8	0.2	1.1	0.2	0.6	1.5	0.2
Fasting Glucose	0.2	0.3	1.1	0.6	-0.5	-1.0	0.8	-0.6	-0.3	-0.4	0.3	0.0	-0.5	-0.5	-0.2	-0.1	0.9	-0.3	0.0	-0.2	-0.5
Type 2 Diabetes (T2D) (2012)	0.2	0.2	1.3	-0.4	-0.4	1.1	-0.3	-0.2	-0.5	-0.3	-0.2	-0.4	0.3	0.6	-0.3	-0.4	0.8	0.5	-0.4	0.4	0.2
Heel T-Score	0.2	1.3	11.2	0.5	1.1	3.4	-0.2	0.3	0.1	1.2	0.7	0.5	0.6	2.2	0.5	0.9	0.0	-0.2	0.6	0.9	0.8
Allergy or Eczema	0.2	0.5	1.6	1.1	0.7	-0.5	0.8	1.3	0.9	0.8	0.9	0.1	0.3	-0.5	0.8	-0.2	-1.1	0.7	0.4	-0.4	-0.0
Vitamin and mineral supplements	0.2	0.2	1.5	0.2	0.2	0.8	0.1	0.2	0.4	0.2	0.1	0.1	0.4	-0.3	0.2	-0.1	-1.2	1.1	0.3	-0.2	-0.2
Multivitamins +/- minerals	0.2	0.2	1.2	-0.1	0.0	-0.5	0.2	0.3	0.1	-0.2	0.1	-0.2	-0.5	0.6	-0.0	0.0	1.1	-1.1	-0.6	0.5	-0.3
Medication: Atenolol	0.2	0.3	2.2	-0.6	0.4	0.5	0.6	0.5	-0.0	0.2	0.2	0.1	-0.8	1.5	0.1	0.2	0.5	0.1	-0.2	-0.0	0.1
Medication: Ramipril	0.2	0.2	0.6	-0.0	0.5	-0.2	0.5	0.7	0.5	0.6	0.5	0.4	-0.1	0.8	0.1	0.6	0.8	0.2	0.2	0.7	0.1
Illnesses of siblings	0.2	0.3	1.5	0.7	-0.4	-0.3	-0.1	-0.1	0.1	-0.4	-0.0	-0.4	0.9	-0.4	-0.0	-0.3	1.1	0.3	0.1	1.2	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.2	-0.5	-0.4	0.7	-0.5	-0.1	-0.0	-0.1	-0.9	-0.2	0.1	0.8	-0.7	-0.3	-0.2	0.2	-0.5	-1.1	-0.3
Length of working week for main job	0.2	0.2	1.3	0.3	0.2	1.1	-0.1	-0.3	-0.0	0.2	-0.0	0.3	0.9	-0.0	-0.0	0.2	0.4	1.0	0.3	0.1	0.4
Migraine (self-reported)	0.2	0.2	2.2	-0.5	-0.2	0.2	-0.5	-0.3	-0.3	0.0	-0.7	-0.0	0.2	-0.5	-0.3	-0.3	-0.5	-0.5	0.1	-1.5	0.2
Had major operations	0.2	0.3	1.6	-0.2	-0.2	1.0	-0.0	0.6	0.3	0.1	-0.2	-0.4	-0.5	0.8	-0.5	-0.3	0.3	-0.2	-1.3	0.4	-0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.3	2.3	-0.6	-0.4	-0.1	-0.1	-0.6	-0.3	-0.6	-0.1	-0.0	-0.3	-1.5	-0.2	-0.1	0.6	0.7	-0.5	0.1	-0.3
Supplements: Vitamin C	0.2	0.3	1.1	0.2	0.4	0.0	0.1	0.1	0.1	0.4	0.4	0.7	0.9	0.2	0.4	0.8	0.3	-1.0	0.7	0.3	1.1
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	3.2	0.3	-0.2	0.5	0.2	0.6	0.5	-0.2	0.0	-0.0	0.5	-0.1	0.2	-0.2	-0.1	0.2	0.0	1.8	-0.4
Risk taking	0.2	0.3	1.2	-0.2	0.3	1.1	-0.5	-0.1	-0.3	0.4	-0.3	0.4	-0.0	0.3	0.0	0.5	-0.1	-0.9	0.8	0.2	0.8
Basal cell carcinoma (self-reported)	0.2	0.2	1.0	-0.5	-0.4	0.3	-0.6	-1.0	-0.9	-0.5	-0.4	-0.4	-0.2	0.4	-0.4	-0.1	0.2	-0.1	0.1	-0.2	-0.2
Heart disease (siblings)	0.2	0.3	1.7	-0.5	-0.3	-0.2	-0.1	-0.3	-0.2	-0.2	-0.7	-0.1	-1.0	0.1	-0.4	-0.0	-1.3	-0.3	-0.4	-0.9	0.1
Impedance of whole body	0.2	1.3	5.2	2.0	0.4	-1.0	0.8	0.8	1.1	0.5	0.2	0.9	2.3	-0.8	1.0	0.7	-0.2	-1.3	1.7	0.8	1.1
Crohns Disease (2017)	0.1	0.2	1.3	0.3	0.0	-0.8	0.3	-0.2	-0.3	-0.4	0.2	-0.3	0.6	-0.7	0.3	-0.2	0.0	0.1	-0.1	1.1	-0.3
Rheumatoid Arthritis	0.1	0.2	0.7	-0.5	-0.5	-0.1	-0.3	-0.8	-0.7	-0.4	-0.4	-0.5	0.1	0.5	-0.4	-0.3	-0.5	-0.5	0.2	-0.5	-0.0
Blood Eosinophil Count	0.1	0.7	4.7	-0.1	-0.3	0.2	-0.6	0.3	-0.6	-0.2	-0.4	-1.1	-0.5	-1.0	-0.6	-1.3	-2.2	0.4	-0.9	-0.9	-0.9
Hair Pigment	0.1	2.1	5.1	2.0	1.8	1.3	1.2	0.9	1.2	2.2	1.2	1.6	2.1	0.2	1.6	1.3	0.3	-0.5	2.3	-0.4	1.5
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.7	-0.7	-0.1	0.0	-0.2	-0.3	-0.0	-0.0	-0.2	-0.0	-0.9	-0.1	-0.3	0.0	0.7	-0.3	-0.4	-0.3	-0.1
Supplements: Zinc	0.1	0.1	0.6	0.1	0.0	0.4	-0.5	-0.1	-0.3	0.5	-0.1	0.0	0.2	0.3	-0.4	0.2	0.5	-0.4	-0.1	-0.3	0.8
Diabetes (self-reported)	0.1	0.1	0.5	-0.4	0.3	0.7	0.1	0.3	-0.2	0.2	0.2	-0.0	-0.5	0.4	-0.0	0.1	0.4	-0.7	-0.4	0.3	0.1
Fluid intelligence score	0.1	0.1	0.6	-0.7	-0.0	0.3	0.1	-0.6	0.2	-0.2	0.1	-0.2	0.2	0.3	-0.2	-0.2	-0.4	0.1	-0.5	-0.8	-0.5
Impedance of arm (right)	0.1	0.3	1.5	1.2	0.1	-0.6	0.4	0.1	0.5	0.1	-0.0	0.2	1.2	0.2	0.4	0.1	-0.2	-0.4	0.7	0.5	0.4
Hair/balding pattern: Pattern 3	0.1	0.1	0.8	-0.1	-0.2	-0.4	-0.1	-0.2	-0.2	-0.4	-0.3	-0.3	-0.5	0.9	-0.2	-0.0	-0.3	-0.6	-0.0	0.1	-0.1
Depression (self-reported)	0.1	0.2	1.1	-0.2	-0.4	-0.8	-0.2	0.1	-0.0	-0.3	-0.4	-0.4	0.0	-1.1	-0.3	-0.3	0.4	-0.2	-0.4	-0.4	-0.4
Illnesses of mother	0.1	0.2	0.7	-0.6	-0.1	-0.8	0.0	0.2	-0.3	-0.3	-0.2	-0.1	-0.8	0.1	-0.2	0.1	0.4	-0.4	-0.1	-0.7	-0.4
Impedance of arm (left)	0.1	0.5	3.3	1.6	0.3	-0.6	0.5	0.1	0.8	0.3	0.2	0.4	1.8	-0.2	0.6	0.2	-0.1	-0.5	0.9	0.6	0.6
Hair/balding pattern: Pattern 4	0.1	0.3	2.0	-0.1	0.0	-1.4	0.3	0.2	0.1	-0.0	-0.0	0.0	-0.5	-1.4	0.2	0.1	-0.2	0.2	0.4	-1.0	0.5
Eye problems/disorders: None of the above	0.1	0.1	0.4	0.2	0.3	0.3	0.0	0.2	0.0	0.4	0.2	0.2	0.5	-0.1	0.1	-0.1	-0.4	0.6	0.2	-0.2	0.2
Medication: Ibuprofen	0.1	0.2	0.8	-0.2	0.0	0.7	-0.2	-0.1	0.0	0.3	-0.5	-0.0	-0.2	0.9	-0.4	-0.1	-0.3	-0.3	-0.4	-0.9	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.1	0.2	0.9	0.3	0.1	-0.3	-0.0	-0.4	-0.2	0.4	-0.1	0.6	-0.2	-0.6	0.1	0.4	0.4	-1.0	0.6	0.3	0.7
Medication: Aspirin	0.1	0.2	0.6	-0.3	-0.0	0.3	-0.0	0.2	-0.6	-0.2	-0.4	-0.5	-0.3	-0.7	-0.2	-0.5	-0.8	-0.7	-0.2	-0.3	-0.3
Medication: Atorvastatin	0.1	0.1	0.7	-0.6	-0.0	-0.1	0.0	-0.1	-0.4	0.1	-0.4	-0.4	0.6	0.3	-0.4	-0.3	0.5	0.1	-0.8	-0.3	-0.1
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Lung FVC	0.0	0.2	1.2	0.0	0.0	0.2	-0.4	0.4	0.0	0.2	0.2	0.3	-0.4	0.3	0.1	0.3	-0.8	0.5	1.1	-0.5	0.1
Weight	0.0	0.2	0.7	-0.8	-0.0	0.5	-0.3	-0.8	-0.4	-0.1	0.2	-0.0	-0.5	-0.7	-0.5	-0.0	0.2	0.3	-0.8	0.1	-0.4
Hip circumference	0.0	0.2	1.3	-0.4	0.2	0.3	-0.1	-0.6	0.0	0.0	0.7	0.4	-0.5	-0.4	-0.1	0.3	1.1	0.3	-0.4	0.7	-0.3
Medication: Gliclazide	0.0	0.1	0.2	-0.3	-0.3	0.3	0.0	-0.0	0.1	-0.4	-0.2	-0.1	-0.3	0.0	-0.2	0.2	-0.1	-0.3	-0.3	0.3	-0.2

Hub : Genes

PBX3

Models

Trait associations