Best TWAS P=2.65e-18 · Best GWAS P=7.06e-18 conditioned to 3.87e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | POLD3 | 0.18 | -0.01 | enet | 48 | 0.00 | 0.2900 | 1.3 | -5.8 | 6.2e-09 | 0.34 | 0.05 | 0.37 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | POLD3 | 0.02 | 0.01 | lasso | 3 | 0.01 | 0.0018 | 7.3 | -8.7 | 2.7e-18 | 0.41 | 0.06 | 0.34 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | POLD3 | 0.03 | 0.00 | blup | 77 | 0.01 | 0.0133 | 7.4 | -6.8 | 1.4e-11 | 0.25 | 0.04 | 0.09 | FALSE |