Best TWAS P=4.19e-10 · Best GWAS P=1.13e-07 conditioned to 0.0853
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | SYTL2 | 0.05 | 0.03 | enet | 9 | 0.02 | 2.4e-02 | -4.9 | 5.4 | 7.5e-08 | 0.40 | 0.06 | 0.82 | FALSE |
| 2 | METSIM | Adipose | PICALM | 0.06 | 0.04 | enet | 26 | 0.05 | 1.7e-07 | -4.6 | -5.5 | 3.9e-08 | -0.55 | 0.23 | 0.74 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CCDC83 | 0.06 | 0.00 | blup | 79 | 0.03 | 4.0e-04 | -4.0 | -6.2 | 4.2e-10 | -0.64 | 0.01 | 0.23 | TRUE |