TWAS hub - SYTL2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0640	0.0250	1.1e-03	0.041	0.015	0.024	0.022	0.029	9.3e-06	5.4e-03	5.7e-04	9.9e-04	1.8e-04
2	GTEx	Artery Tibial	0.0766	0.0355	5.3e-03	-0.002	NA	-0.001	NA	-0.002	4.8e-01	NA	4.2e-01	NA	5.6e-01
3	GTEx	Cells Transformed fibroblasts	0.1410	0.0470	4.4e-05	0.032	NA	0.040	NA	0.051	1.9e-03	NA	5.3e-04	NA	1.1e-04
4	GTEx	Muscle Skeletal	0.1046	0.0353	1.8e-07	0.109	NA	0.096	NA	0.104	7.9e-11	NA	1.1e-09	NA	2.2e-10
5	GTEx	Nerve Tibial	0.0547	0.0247	5.4e-03	0.027	NA	0.016	NA	0.012	5.2e-03	NA	2.4e-02	NA	4.2e-02
6	GTEx	Testis	0.1250	0.0580	7.5e-03	0.091	NA	0.043	NA	0.059	7.5e-05	NA	5.6e-03	NA	1.3e-03
7	YFS	Blood	0.3575	0.0470	0.0e+00	0.266	0.307	0.311	0.319	0.302	4.2e-87	7.0e-103	3.4e-104	2.2e-107	1.1e-100
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0423	0.0216	2.0e-04	0.033	0.029	0.021	NA	0.031	1.1e-04	2.8e-04	1.7e-03	NA	1.9e-04
9	TCGA	Lung Adenocarcinoma	0.0137	0.0085	9.0e-03	0.025	0.016	0.016	NA	0.025	5.3e-04	5.4e-03	4.6e-03	NA	6.3e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Supplements: Glucosamine	9.2	12.0	18.9	2.0	-1.8	-3.9	-3.9	-4.1	2.1	-4.3	-4.3	-3.4
Number of incorrect matches in round	6.2	10.3	18.9	3.1	-0.8	-3.7	-3.5	-3.5	0.4	-4.3	-3.3	-3.8
Tinnitus: Yes, but not now, but have in the past	5.5	5.9	9.2	-0.7	2.2	2.9	3.0	2.7	-0.9	2.7	2.8	2.5
Number of treatments/medications taken	5.0	9.0	13.3	2.0	-1.2	-3.6	-3.3	-3.4	2.5	-3.2	-3.6	-3.2
Chronic bronchitis/emphysema (father)	4.2	4.9	8.2	-0.3	2.0	2.4	2.6	2.7	-0.7	2.3	2.9	2.4
Comparative height size at age 10	4.1	22.6	33.8	-0.6	5.0	5.8	5.7	5.5	-1.4	4.1	5.8	5.3
Medication: Aspirin	3.6	4.7	7.1	1.1	-1.6	-2.7	-2.6	-2.3	2.5	-1.5	-2.6	-2.0
Mouth/teeth dental problems: Bleeding gums	3.4	4.5	6.8	-1.9	0.9	2.4	2.4	2.6	0.7	2.6	2.5	2.1
Medication: Aspirin	3.4	4.5	6.9	1.5	-1.3	-2.6	-2.5	-2.1	2.5	-1.7	-2.6	-1.8
Mineral and other dietary supplements	3.3	4.4	8.7	-1.7	0.3	2.1	2.3	1.9	-3.0	2.4	2.2	2.1
Angina	3.1	4.0	6.5	0.6	-1.4	-2.4	-2.3	-2.5	1.2	-1.9	-2.5	-2.2
Wears glasses or contact lenses	3.1	3.6	9.4	0.4	-1.2	-2.7	-1.9	-1.6	0.6	-2.0	-3.1	-1.7
Eye problems/disorders: Glaucoma	3.0	3.5	18.3	-1.0	1.2	1.4	1.3	1.3	-4.3	1.4	0.7	1.8
Cholesterol lowering medication	3.0	4.4	8.9	2.0	-0.6	-2.2	-2.2	-2.3	1.3	-3.0	-2.3	-2.0
Age at First Birth	2.8	4.1	7.6	2.3	-2.0	-2.1	-2.8	-1.7	-0.4	-2.2	-1.8	-2.1
Standing height	2.8	28.0	42.8	-0.4	5.6	6.5	6.0	6.2	-2.6	4.6	6.2	6.1
Angina (self-reported)	2.8	3.7	5.9	0.4	-1.5	-2.4	-2.2	-2.4	0.9	-1.9	-2.4	-2.1
Medication: Bendroflumethiazide	2.8	4.3	7.5	1.1	-1.7	-2.3	-2.6	-2.3	0.7	-2.3	-1.9	-2.7
Myopia	2.8	4.1	7.0	-0.6	-2.6	-2.2	-2.6	-2.2	-0.7	-1.9	-2.5	-1.7
Type 2 Diabetes (T2D) (2018)	2.7	5.1	8.9	1.4	-1.5	-3.0	-2.2	-2.5	1.3	-2.7	-2.8	-2.0
Handedness (chirality/laterality): Left-handed	2.6	3.1	5.3	-0.8	-2.2	-1.9	-2.0	-1.8	0.0	-1.2	-2.1	-2.3
Medication: Atorvastatin	2.6	3.3	8.6	-0.1	-1.1	-2.2	-2.3	-1.3	-0.3	-2.2	-1.7	-2.9
Heart disease (siblings)	2.6	3.2	5.3	-0.2	-2.2	-2.3	-2.2	-2.2	0.2	-1.7	-1.9	-1.6
Sitting height	2.5	17.5	28.9	-1.4	3.7	5.0	4.5	5.4	-3.4	3.8	4.7	4.3
Medication for cholesterol, blood pressure or diabetes	2.5	4.1	6.0	-0.9	1.5	2.5	2.2	2.2	-1.9	2.0	2.3	2.2
Leg pain on walking	2.5	3.1	8.0	0.9	-0.8	-2.3	-1.7	-2.1	1.7	-1.6	-2.8	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	2.5	5.1	8.1	-1.8	1.7	2.8	2.5	2.3	-2.1	2.3	2.7	2.0
Schizophrenia vs Biploar Disorder	2.4	3.1	6.7	1.6	-0.2	-1.9	-2.0	-2.1	-0.2	-2.6	-1.8	-1.8
Average weekly fortified wine intake	2.4	2.9	5.9	-0.7	-0.2	1.8	1.9	1.2	-2.4	1.9	1.7	2.1
Taking other prescription medications	2.4	3.7	6.2	2.5	-0.2	-2.3	-2.0	-2.0	1.2	-2.0	-2.2	-1.8
Height	2.3	44.6	70.1	-0.8	6.2	8.4	7.6	7.7	-2.8	6.7	8.0	7.5
Medication for hormone replacement therapy	2.3	2.6	5.4	-0.9	0.8	1.8	1.9	1.6	0.3	2.3	1.8	1.9
Breastfed as a baby	2.3	2.9	5.1	-1.4	1.0	2.1	1.9	2.2	-0.8	1.6	2.2	1.4
Medication: Blood pressure	2.3	4.1	6.7	0.6	-1.7	-2.3	-2.6	-2.1	1.2	-2.5	-2.1	-2.4
Birth weight	2.2	4.7	8.4	-0.4	2.3	2.5	2.9	2.4	-0.8	1.9	2.4	2.6
Mean time to correctly identify matches	2.2	4.2	8.0	1.3	-1.6	-2.4	-2.2	-1.8	2.8	-1.9	-1.8	-2.2
High cholesterol (Self-reported)	2.2	3.9	5.6	1.5	-1.3	-2.3	-1.9	-2.4	2.1	-2.1	-2.3	-1.6
Triglycerides	2.1	3.5	7.9	1.1	-0.5	-2.4	-1.9	-2.1	0.7	-2.8	-2.1	-1.8
Happiness	2.1	2.6	4.8	0.9	1.9	2.2	1.4	1.6	0.7	1.1	1.7	2.2
Worry too long after embarrassment	2.1	3.6	5.1	-1.6	1.0	2.3	1.8	2.3	-0.5	2.3	2.2	2.2
Number of self-reported non-cancer illnesses	2.1	3.7	5.9	1.2	-1.4	-2.4	-1.5	-1.8	2.3	-2.1	-1.9	-2.3
Ever had bowel cancer screening	2.0	2.4	6.5	2.2	0.9	-1.2	-1.4	-0.8	0.2	-2.6	-0.7	-2.1
Asthma (self-reported)	2.0	4.0	9.2	-0.7	-1.5	-2.5	-2.2	-2.3	0.3	-1.7	-2.0	-3.0
Severe depression (siblings)	1.9	2.1	4.4	1.9	-0.8	-1.5	-1.6	-1.5	2.1	-0.4	-0.9	-1.5
Asthma	1.9	3.7	8.5	-0.6	-1.4	-2.5	-2.1	-2.2	0.1	-1.6	-2.1	-2.9
Bipolar Disorder (2018)	1.8	2.8	10.9	-3.3	-1.0	1.5	1.1	2.1	-0.7	1.2	2.0	-0.1
Chronotype (morning person)	1.8	4.2	7.6	-1.4	0.3	2.1	2.6	2.3	0.2	2.8	2.0	2.7
Qualifications: CSEs or equivalent	1.8	2.4	5.7	-0.0	1.1	1.7	2.4	1.2	-1.3	1.6	1.9	1.7
Ever unenthusiastic/disinterested for a whole week	1.8	2.3	3.5	0.2	-1.0	-1.8	-1.8	-1.7	1.1	-1.8	-1.9	-1.4
Medication: Simvastatin	1.8	2.6	4.8	2.2	0.3	-1.6	-1.3	-2.1	1.8	-1.5	-2.1	-0.3
Medication: Cholesterol lowering	1.8	2.8	5.7	1.4	-0.8	-2.2	-1.7	-1.9	1.6	-1.2	-2.4	-1.1
Health satisfaction	1.8	2.4	6.8	2.6	1.0	-1.0	-1.0	-1.5	2.4	-1.4	-1.1	-0.8
Mouth/teeth dental problems: Loose teeth	1.8	2.1	4.7	-1.0	0.4	1.6	1.4	2.2	0.6	2.0	1.7	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.2	4.7	0.1	-1.6	-1.5	-1.8	-0.9	-0.7	-2.0	-1.3	-2.2
Illnesses of father: Heart disease	1.8	2.5	8.8	-0.8	-3.0	-1.5	-1.3	-1.1	1.7	-0.7	-1.4	-1.4
Fasting Glucose	1.7	2.0	3.3	0.3	-0.1	-1.8	-1.8	-1.6	0.8	-1.6	-1.7	-1.7
Waist Hip Ratio (WHR)	1.7	7.5	14.9	0.6	-3.1	-3.9	-2.5	-3.5	2.2	-1.9	-3.3	-2.2
Townsend deprivation index at recruitment	1.7	2.4	3.0	1.3	0.3	-1.6	-1.5	-1.7	1.7	-1.7	-1.7	-1.7
Serious illness, injury or assault to yourself	1.7	2.1	3.6	1.0	-1.8	-1.8	-1.3	-1.8	1.3	-0.4	-1.9	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.7	2.0	4.3	-0.6	-1.9	-2.0	-1.0	-1.5	1.0	-0.4	-2.1	-1.0
Smoking status: Previous	1.7	2.5	5.7	-0.4	0.3	-1.5	-2.4	-0.9	1.5	-1.7	-1.8	-2.2
Diabetes (father)	1.6	2.0	7.0	-1.2	-2.6	-0.9	-0.9	-0.5	2.1	-0.6	-1.3	-1.2
Past tobacco smoking	1.6	2.9	8.3	1.0	-0.0	1.4	2.2	1.1	-1.5	2.3	1.2	2.9
Diabetes diagnosed by doctor	1.6	2.6	4.4	0.9	-0.4	-1.9	-1.5	-1.5	1.8	-2.1	-2.0	-1.5
Major Depression (MDD)	1.5	1.9	13.4	0.4	-0.3	-0.6	-1.0	-0.5	3.7	-0.2	-0.4	-1.2
Respiratory disease	1.5	3.3	8.8	-1.3	-1.0	-2.1	-2.0	-1.8	1.0	-2.0	-1.6	-3.0
Ever had hysterectomy (womb removed)	1.5	1.7	6.3	2.5	0.2	-1.3	-0.6	-1.7	0.2	-1.3	-1.0	-0.9
Vitamin and mineral supplements	1.5	2.1	5.0	-2.0	-1.8	1.0	1.2	1.3	-0.2	2.2	1.1	1.1
Number of full sisters	1.5	1.9	4.3	0.9	1.0	1.4	1.3	1.2	-2.1	0.8	1.4	1.8
Commuting to job workplace: Cycle	1.5	1.8	4.8	0.3	-2.2	-1.2	-1.7	-1.4	1.6	-0.3	-1.3	-0.9
Reaction Time	1.4	2.7	4.8	1.4	-0.6	-1.9	-1.9	-1.4	2.2	-1.5	-1.4	-1.8
Bipolar Disorder (2011)	1.4	1.3	4.9	-2.2	-1.2	0.7	0.8	1.2	-0.4	0.5	1.4	0.6
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	2.6	1.0	1.6	1.4	1.6	0.9	0.2	0.9	1.4	1.5
Hand grip strength (right)	1.4	3.7	8.8	-0.9	1.4	2.6	1.6	3.0	-0.4	1.6	2.6	1.6
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	4.5	0.8	-1.1	-2.1	-1.3	-1.8	-0.5	-0.8	-1.9	-1.1
Peak expiratory flow (PEF)	1.4	3.3	6.1	-1.1	1.0	2.1	1.6	2.5	-1.4	2.3	1.2	2.4
Glaucoma (self-reported)	1.4	1.6	13.3	-0.6	0.2	0.1	0.3	-0.0	-3.6	0.5	-0.4	0.6
Supplements: Calcium	1.4	1.5	5.8	2.1	1.4	-0.5	-0.3	-0.4	2.4	-0.5	-0.4	-0.4
Cardiovascular Disease	1.3	4.2	8.4	0.4	-1.4	-2.0	-1.8	-2.3	2.9	-2.3	-1.4	-2.7
Average weekly spirits intake	1.3	1.6	6.9	1.4	2.6	0.6	1.5	0.1	-1.4	-0.1	0.8	0.8
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.1	5.7	-0.7	-2.4	-1.9	-2.0	-2.0	-0.3	-1.5	-1.5	-2.4
Qualifications: nursing, teaching	1.3	2.1	5.8	-0.3	-1.9	-1.5	-1.0	-0.9	-2.4	-1.0	-1.6	-1.3
Illnesses of father: High blood pressure	1.3	1.5	5.5	-2.3	-2.3	-0.1	0.2	0.2	1.5	-0.2	0.3	-0.9
Ever used hormone-replacement therapy (HRT)	1.2	1.5	3.5	-1.9	-1.7	-0.6	-0.8	-0.4	1.8	-0.5	-0.5	-1.5
Medication: Co-codamol	1.2	1.3	2.5	0.7	-1.4	-1.6	-0.8	-1.6	1.1	-0.4	-1.1	-1.2
Illnesses of siblings	1.2	1.6	7.2	1.8	2.7	0.6	0.6	0.8	-1.7	-0.3	0.3	0.3
Arm fat percentage (right)	1.2	4.8	9.8	2.2	-0.7	-2.9	-1.1	-2.6	3.1	-1.4	-3.1	-0.9
Medication for cholesterol	1.2	1.9	3.1	-1.7	-0.2	1.3	1.4	1.3	-1.8	1.4	1.5	1.1
Alcohol drinker status: Never	1.2	1.4	3.6	1.4	-0.7	-1.4	-0.8	-1.6	1.9	-0.1	-1.4	-0.1
Medication: Omeprazole (e.g. Zanprol)	1.2	1.4	2.8	-0.2	-1.3	-1.7	-1.1	-1.1	1.6	-0.4	-1.6	-0.8
Prostate Cancer	1.1	1.5	4.3	-0.9	2.1	1.5	0.7	1.4	0.4	0.9	0.9	1.5
Type 2 Diabetes (T2D) (2012)	1.1	1.2	2.9	0.7	0.0	-1.7	-0.6	-1.6	-0.1	-1.5	-1.4	-0.8
Blood Platelet Count	1.1	12.7	26.0	3.0	-2.0	-4.2	-4.1	-5.1	2.6	-3.0	-4.3	-2.7
Smoking Status	1.1	2.6	6.2	0.2	0.2	-1.4	-1.8	-1.3	2.5	-1.8	-1.0	-2.4
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	4.3	-1.5	-2.1	-1.1	-0.3	-0.5	1.3	-0.5	-0.7	-1.1
Hearing difficulty/problems with background noise	1.1	1.7	2.6	1.6	0.3	-1.5	-1.5	-1.1	1.5	-1.3	-1.6	-0.9
Time employed in main current job	1.1	1.3	5.0	1.2	2.2	0.9	0.9	1.0	-0.2	0.5	1.1	1.0
Arm fat-free mass (right)	1.1	5.4	11.0	0.0	1.7	2.7	3.3	3.0	-0.2	1.9	2.7	2.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.1	1.5	7.5	1.2	1.7	-0.1	-0.2	-0.4	2.7	-0.1	0.5	-1.0
Mood swings	1.1	2.0	10.0	-1.5	-1.3	-0.3	-0.8	-0.7	3.2	-0.5	0.2	-1.5
Heart attack/myocardial infarction (self-reported)	1.1	1.4	2.5	1.6	-0.1	-1.3	-1.5	-0.8	1.0	-1.4	-1.1	-1.3
Bipolar Disorder or Schizophrenia	1.0	2.4	14.3	-3.8	-1.4	0.7	0.7	1.1	-0.1	0.4	1.4	-0.7
Ulcerative Colitis (UC)	1.0	1.9	3.7	-1.1	-1.9	-1.4	-1.6	-1.1	0.6	-1.3	-1.0	-1.9
Schizophrenia (2014)	1.0	2.2	6.2	-2.5	-1.9	-1.3	-0.9	-0.6	0.8	-1.4	-0.4	-2.1
Lung FEV1/FVC ratio	1.0	5.3	16.4	1.6	2.7	2.1	2.2	1.7	-0.1	2.8	1.0	4.0
Hand grip strength (left)	1.0	2.5	7.1	-0.9	0.8	2.1	1.4	2.7	-0.3	1.2	2.3	0.9
Supplements: Zinc	1.0	1.1	3.0	-1.6	-1.4	-0.5	-0.9	0.1	0.7	-1.0	-0.5	-1.7
Medication: Metformin	1.0	1.4	3.0	1.5	0.1	-1.4	-0.8	-1.4	-0.2	-1.7	-1.2	-1.1
Heel bone mineral density (BMD) T-score, automated (right)	1.0	2.3	4.9	-0.1	-1.9	-1.8	-1.9	-1.7	0.3	-1.2	-1.2	-2.2
Heart attack	1.0	1.3	2.1	1.4	-0.2	-1.4	-1.4	-0.7	0.7	-1.4	-1.0	-1.4
Forced expiratory volume in 1-second (FEV1)	1.0	3.2	5.0	0.2	1.9	2.1	1.7	2.0	-1.1	2.1	1.8	2.2
Hypothyroidism/myxoedema (self-reported)	1.0	1.9	2.6	1.5	-1.0	-1.4	-1.6	-1.5	1.0	-1.5	-1.3	-1.5
Medication for pain relief, constipation, heartburn	1.0	1.8	6.8	-0.4	0.7	1.5	1.2	1.3	-2.6	0.7	1.4	0.6
Medication: Allopurinol	1.0	1.3	2.7	-0.4	-1.1	-1.1	-1.3	-0.7	1.6	-1.4	-1.2	-1.1
Medication: Seretide 50 evohaler	1.0	1.2	1.9	-1.1	-0.8	-1.3	-1.2	-0.9	0.7	-0.7	-1.4	-1.4
Arm fat percentage (left)	1.0	4.1	8.7	2.0	-0.9	-2.6	-0.9	-2.4	3.0	-1.2	-2.9	-0.7
Average weekly red wine intake	1.0	1.5	4.0	-0.2	-0.6	-1.6	-1.7	-0.8	0.2	-1.1	-1.4	-2.0
Friendships satisfaction	1.0	1.2	1.9	-0.7	1.2	1.4	1.2	1.3	0.9	0.8	1.2	1.1
Illnesses of father: None of the above (group 1)	1.0	1.2	5.7	0.8	2.0	0.1	-0.0	-0.5	-2.4	-0.3	-0.2	0.7
Ever taken oral contraceptive pill	1.0	1.1	5.3	1.1	1.4	0.1	-0.4	-0.3	-2.3	-0.8	-0.2	-0.2
Ever had prostate specific antigen (PSA) test	1.0	1.1	3.6	1.6	1.9	0.4	-0.1	0.5	-1.5	-0.9	0.7	0.1
Age started oral contraceptive pill	1.0	1.3	4.0	2.0	0.1	-1.0	-1.2	-1.4	0.3	-0.9	-1.3	-0.5
Unable to work because of sickness or disability	1.0	1.3	3.0	0.9	-1.1	-1.3	-0.8	-1.7	-0.6	-1.0	-0.5	-1.7
Mean Putamen Volume	0.9	1.0	6.2	-0.1	-0.1	-0.7	-0.5	-0.9	2.5	0.5	-1.1	-0.2
Diabetes (mother)	0.9	1.2	2.4	-0.1	-1.2	-0.7	-1.1	-0.9	1.6	-1.4	-0.6	-1.3
Hair/balding pattern: Pattern 2	0.9	1.1	2.2	-1.3	0.2	1.5	0.9	1.1	0.2	0.9	1.3	1.2
Lung cancer (father)	0.9	1.0	5.0	-2.2	-0.5	0.4	0.7	0.4	-1.5	0.6	0.5	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.9	4.9	0.5	1.7	1.9	1.7	2.0	-0.4	2.2	1.8	2.1
Length of working week for main job	0.9	1.0	3.2	-1.3	0.0	0.4	1.7	0.7	-1.8	0.2	0.8	0.4
Tense / ‘highly strung’	0.9	1.5	3.3	-0.3	-1.1	-1.1	-1.8	-1.1	1.3	-1.0	-0.9	-1.7
High blood pressure (siblings)	0.9	1.2	6.1	-0.7	-1.8	-0.5	-0.6	-0.8	2.5	0.3	-0.0	-0.1
Medication: Ibuprofen	0.9	1.1	2.2	0.0	-1.0	-1.4	-1.3	-1.0	0.4	-1.0	-0.8	-1.5
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	3.2	1.8	-0.2	-1.2	-1.6	-1.6	0.6	-1.1	-1.0	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	2.2	0.8	-1.1	-1.5	-0.4	-1.4	1.1	-0.4	-1.4	-0.6
Back pain experienced in last month	0.9	1.4	3.5	1.2	1.9	1.0	1.3	1.1	0.0	0.3	1.3	1.4
Average weekly champagne plus white wine intake	0.9	1.2	2.3	1.5	-0.2	-0.9	-1.5	-1.1	1.2	-0.8	-1.4	-0.5
Financial situation satisfaction	0.9	1.1	3.1	0.8	1.6	1.5	0.7	0.5	0.5	-0.6	1.8	0.3
Arm fat-free mass (left)	0.9	4.7	10.6	0.4	1.8	2.4	3.2	2.8	0.1	1.7	2.3	2.6
Average weekly beer plus cider intake	0.9	1.3	3.6	-0.2	1.1	1.2	1.1	1.0	-1.9	0.5	1.8	-0.1
Alzheimer’s Disease (including proxy)	0.8	1.2	6.4	0.5	-1.0	-0.3	-0.5	-1.5	-2.5	0.0	-0.9	0.2
HbA1C	0.8	0.9	2.4	-1.5	0.5	0.9	0.7	1.0	-0.9	-0.4	1.2	0.6
Blood Red Count	0.8	7.3	14.1	1.6	-2.1	-3.5	-2.7	-3.5	1.8	-2.3	-3.8	-2.0
Hypothyroidism (self reported)	0.8	1.9	3.2	1.2	-0.8	-1.4	-1.8	-1.5	0.7	-1.6	-1.4	-1.6
Medication: Levothyroxine sodium	0.8	1.3	3.7	1.9	-0.0	-1.0	-1.2	-1.3	1.0	-0.9	-1.0	-1.0
Hair/balding pattern: Pattern 4	0.8	1.8	5.8	-1.4	0.7	1.2	1.6	1.2	-2.4	0.2	1.6	0.7
Gout (self-reported)	0.8	1.1	2.2	0.1	-0.7	-1.0	-1.3	-0.7	1.2	-1.5	-0.9	-1.4
Medication: Amlodipine	0.8	1.2	2.0	1.1	-0.3	-0.9	-1.4	-1.2	0.8	-1.2	-0.9	-1.3
Leg fat percentage (right)	0.8	2.7	5.3	2.0	-0.4	-2.0	-0.5	-1.9	2.3	-1.8	-2.0	-0.6
Medication: Omeprazole	0.8	1.0	2.2	0.1	-0.6	-1.5	-0.8	-1.1	1.3	-0.5	-1.5	-0.4
Arm predicted mass (right)	0.8	3.9	8.5	-0.1	1.3	2.3	2.9	2.6	-0.1	1.4	2.3	2.3
Supplements: Vitamin C	0.8	1.0	2.0	0.7	1.2	-0.8	-1.2	-0.7	0.7	-1.4	-1.3	-0.3
Pain type(s) experienced in last month: Hip pain	0.8	1.0	2.2	-0.7	-1.5	-0.6	-0.4	-0.6	1.3	-1.4	-0.9	-0.9
Supplements: Fish oil (including cod liver oil)	0.8	1.0	3.8	-0.1	-0.2	-0.6	-1.1	-0.4	1.9	-1.4	-0.6	-1.2
Ever smoked	0.8	1.4	5.2	-0.8	0.5	-0.6	-1.1	-0.6	1.2	-1.7	-0.2	-2.3
Arm predicted mass (left)	0.8	4.2	9.7	0.3	1.8	2.2	3.1	2.6	0.0	1.6	2.1	2.5
Alzheimer’s Disease (in mother)	0.7	0.8	6.2	0.5	-0.1	0.1	0.0	-0.4	-2.5	0.3	-0.2	0.4
Body mass index (BMI)	0.7	2.8	7.8	1.4	-1.3	-2.1	-0.4	-1.7	2.8	-1.0	-2.1	-0.8
Impedance of leg (left)	0.7	3.2	8.0	-0.5	2.3	2.0	1.1	1.6	-2.8	0.5	2.0	1.8
Waist circumference	0.7	2.5	6.4	1.7	-0.5	-2.1	-0.3	-1.6	2.5	-1.1	-1.9	-0.6
Nervous feelings	0.7	1.3	2.6	0.8	-0.8	-1.6	-1.5	-1.5	0.6	-1.1	-1.0	-1.0
Qualifications: None of the above	0.7	1.6	2.9	-0.6	1.1	1.5	1.5	1.2	0.2	1.2	1.6	1.7
Trunk fat-free mass	0.7	3.8	7.9	-0.1	1.6	2.3	2.6	2.8	0.1	1.6	2.3	2.0
Alcohol intake versus 10 years previously	0.7	1.1	2.2	-0.1	1.1	0.7	1.3	1.1	0.7	1.5	0.7	1.2
Hair/balding pattern: Pattern 3	0.7	1.0	2.0	0.9	-0.9	-1.2	-1.1	-1.1	0.3	-0.7	-1.1	-1.4
Depression (self-reported)	0.7	0.9	2.9	1.0	0.0	-0.7	-0.8	-1.7	0.9	-1.0	-0.3	-1.0
Prospective memory result	0.7	0.8	1.9	1.1	-0.5	-0.9	-0.7	-1.4	-0.7	-1.2	-0.6	-0.6
Illnesses of mother	0.7	0.8	2.7	1.6	1.5	0.4	0.7	0.5	-0.3	0.5	0.4	1.0
Trunk predicted mass	0.7	3.8	7.8	-0.1	1.5	2.3	2.6	2.8	-0.1	1.6	2.3	2.0
Forced vital capacity (FVC), Best measure	0.7	2.6	5.0	-0.2	1.4	2.0	1.5	2.2	-0.5	1.9	2.2	1.4
Comparative body size at age 10	0.7	2.0	7.8	-1.4	-2.8	-1.3	-0.5	-0.8	1.4	0.0	-1.1	-1.6
Number of full brothers	0.7	0.9	3.8	-1.3	-2.0	-0.4	-0.4	-0.4	-1.1	-0.6	0.0	-0.5
Number of children fathered	0.7	0.8	2.3	-1.5	-0.5	0.9	0.4	1.1	-0.9	0.9	0.8	0.7
Emphysema/chronic bronchitis	0.7	0.8	2.0	-0.9	0.8	0.9	1.2	0.8	0.8	-0.2	1.4	-0.6
Eye problems/disorders: Cataract	0.7	0.9	1.6	0.8	-0.9	-1.2	-0.7	-1.3	0.4	-1.0	-0.6	-1.2
Leg fat percentage (left)	0.7	2.5	5.7	1.9	-0.6	-1.9	-0.3	-1.6	2.4	-1.6	-1.9	-0.6
Alzheimer’s Disease (in father)	0.6	0.6	2.3	0.4	-1.1	-0.6	-0.4	-1.5	0.8	0.4	-0.9	0.2
Crohns Disease (2012)	0.6	1.0	3.6	1.9	-0.1	-1.0	-0.6	-1.2	0.9	-0.8	-0.3	-1.0
Ulcerative Colitis	0.6	0.8	2.3	-1.4	-1.5	-0.4	-0.9	-0.0	-1.0	-0.5	-0.4	-0.8
Sensitivity / hurt feelings	0.6	1.0	4.8	-1.7	-2.2	-0.4	-0.9	0.4	0.0	0.3	-0.3	-0.7
Hearing difficulty/problems: Yes	0.6	0.9	1.9	0.0	0.2	-1.2	-1.3	-0.9	0.0	-0.9	-1.4	-1.0
Impedance of leg (right)	0.6	2.7	7.2	-0.3	2.5	1.8	0.9	1.2	-2.7	0.1	1.7	1.6
Current tobacco smoking	0.6	1.0	2.8	0.2	-0.5	-0.7	-0.6	-0.9	1.6	-1.4	-0.0	-1.7
Allergy	0.6	1.3	3.1	1.3	0.8	1.8	0.9	0.8	0.4	0.7	1.7	1.3
Body fat percentage	0.6	2.4	5.8	2.3	0.3	-1.6	0.1	-1.6	2.4	-0.9	-1.9	0.4
Wheeze or whistling in the chest in last year	0.6	1.0	4.7	-1.0	0.1	-0.4	-0.6	-0.6	2.2	-0.5	-0.1	-1.4
Shortness of breath walking on level ground	0.6	0.7	2.0	0.7	0.3	-1.0	-0.9	-0.9	1.4	-0.2	-1.0	-0.5
Qualifications: College or University degree	0.6	1.9	4.6	-0.9	-1.1	-1.1	-2.1	-1.0	0.6	-1.0	-1.9	-1.7
Overall health rating	0.6	1.4	4.5	2.1	0.9	-0.7	0.2	-1.1	1.5	-1.7	-0.2	-0.4
Age at last live birth	0.6	0.8	2.4	0.1	-0.6	-0.6	-1.5	-0.6	0.1	-1.1	-0.7	-1.5
Whole body fat-free mass	0.6	3.4	7.3	0.0	1.4	2.1	2.7	2.4	0.6	1.7	2.0	2.0
Commuting to job workplace: Walk	0.6	0.7	2.2	-0.5	-0.0	0.8	0.8	0.4	0.5	1.5	0.4	1.3
Osteoporosis (self-reported)	0.6	0.8	1.4	0.3	-1.2	-1.0	-0.5	-1.1	1.1	-0.3	-1.1	-0.8
Smoking status: Current	0.6	1.0	3.0	0.2	-0.5	-0.7	-0.6	-1.0	1.1	-1.7	0.1	-1.7
Whole body water mass	0.6	3.6	8.0	0.1	1.4	2.1	2.8	2.5	0.4	1.7	2.0	2.1
Guilty feelings	0.6	0.9	3.8	1.1	2.0	0.6	0.5	0.4	0.4	0.7	1.0	1.0
Mother’s age at death	0.6	0.7	1.2	-0.1	-0.2	-0.5	-1.1	-0.9	-1.1	-1.1	-0.9	-1.0
Medication: Paracetamol	0.6	1.0	4.5	-0.7	0.0	-0.7	-0.8	-0.7	2.1	-0.7	-0.6	-1.2
Basal metabolic rate	0.6	3.1	7.2	0.4	1.5	1.8	2.7	2.1	0.9	1.5	1.7	2.1
Number of operations (self-reported)	0.6	0.9	2.1	0.2	-0.4	-1.3	-0.7	-1.3	-0.1	-1.0	-1.4	-0.8
Ever depressed for a whole week	0.6	0.8	3.6	1.9	1.4	-0.6	-0.4	-0.4	0.5	-0.6	-0.4	-0.2
Depressed Affect (Nagel 2018)	0.5	1.1	7.5	-0.9	-0.5	0.4	0.0	0.1	2.7	-0.1	0.6	-0.6
Breast Cancer	0.5	1.3	3.0	-0.4	0.1	1.3	1.5	0.5	-1.2	1.5	1.7	0.7
Neuroticism (2016)	0.5	0.7	2.7	-1.6	-1.0	-0.5	-0.6	-0.2	-0.5	-0.2	-0.4	-1.1
Heel T-Score	0.5	3.8	8.6	-0.5	-2.9	-1.7	-2.8	-0.9	-1.1	-2.1	-1.8	-2.2
BMI	0.5	2.8	6.1	0.9	-1.6	-2.3	-0.6	-1.8	2.2	-1.4	-2.5	-0.6
Allergy or Eczema	0.5	1.4	3.9	-1.3	-0.7	-1.9	-0.9	-1.0	-0.5	-0.9	-2.0	-0.9
Tanning	0.5	5.5	10.4	-1.2	-3.1	-2.4	-3.2	-2.1	2.1	-1.4	-2.6	-2.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	2.8	-0.6	0.2	-0.2	-1.1	-0.7	1.7	-0.5	-0.5	-0.9
Leg fat-free mass (left)	0.5	2.6	6.4	0.6	1.2	1.5	2.5	1.6	1.3	1.7	1.4	1.9
Fed-up feelings	0.5	0.8	5.4	-0.3	0.3	0.8	0.5	0.4	2.3	0.6	0.6	0.6
Stomach or abdominal pain in last month	0.5	0.6	1.1	1.1	-0.6	-1.0	-0.6	-0.9	0.1	-0.7	-0.9	-0.6
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.0	-0.1	-1.4	-1.1	-0.7	-0.5	-0.2	0.0	-1.0	-0.3
Leg predicted mass (left)	0.5	2.4	6.2	0.5	1.1	1.4	2.5	1.5	1.2	1.6	1.4	1.9
Pain all over the body in last month	0.5	0.5	3.2	0.7	-0.1	-0.1	0.3	-0.6	1.8	-0.4	0.4	-0.1
Diabetes (self-reported)	0.5	0.8	1.4	0.0	-0.6	-1.0	-0.7	-0.6	1.2	-1.2	-1.1	-1.0
Worrier / anxious feelings	0.5	0.9	1.6	-0.2	0.7	1.2	0.9	1.0	0.7	1.1	1.3	1.0
Pulse rate	0.5	0.8	2.7	1.7	0.7	0.0	-0.3	-0.3	1.6	-0.9	0.2	-0.6
Ever highly irritable/argumentative for 2 days	0.5	0.6	1.6	-1.2	0.6	1.1	0.6	1.0	-0.1	0.2	0.8	0.2
Loud music exposure frequency	0.5	0.6	3.9	0.6	2.0	0.4	0.2	0.2	-0.6	0.2	0.5	0.1
Leg fat-free mass (right)	0.5	2.9	7.3	0.2	1.0	1.7	2.7	1.9	1.2	1.9	1.6	1.9
Long-standing illness, disability or infirmity	0.5	0.8	2.8	1.2	0.6	-0.5	-0.4	-0.9	0.2	-1.7	0.0	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.5	0.5	1.9	0.4	0.7	-0.5	-0.5	-0.6	-0.8	-1.4	-0.2	-0.9
Medication: Gliclazide	0.5	0.5	2.2	0.1	-1.0	-0.8	-0.3	-0.5	-1.5	-0.3	-0.5	-0.6
Leg predicted mass (right)	0.5	2.9	7.2	0.3	1.1	1.6	2.7	1.9	1.3	2.0	1.6	1.9
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.3	-1.1	-0.8	0.3	1.0	0.4	-1.1	0.8	0.4	0.6
Pack years of smoking	0.5	0.8	1.7	0.7	-0.7	-0.8	-0.2	-1.1	1.1	-1.3	-0.7	-0.9
Schizophrenia (2018)	0.4	0.8	5.0	-2.2	-1.0	-0.3	0.1	-0.2	0.3	-0.5	0.2	-0.9
Crohns Disease (2017)	0.4	0.9	3.7	1.9	-0.2	-0.5	0.2	-1.4	1.1	-0.5	0.3	-0.9
Irritable Bowel Disease (IBD)	0.4	1.0	2.4	0.6	-1.3	-1.0	-0.7	-1.2	0.5	-1.1	-0.3	-1.5
Coronary Artery Disease (CAD)	0.4	0.4	1.3	-0.9	0.2	-0.4	0.2	-1.1	0.7	1.1	0.1	-0.2
Systolic Blood Pressure	0.4	1.9	5.7	-0.6	-0.8	-1.2	-1.6	-1.1	1.4	-1.8	-0.7	-2.4
Frequency of depressed mood in last 2 weeks	0.4	0.6	2.7	-1.6	-0.3	0.5	-0.2	0.4	-0.3	0.3	1.1	-0.6
Trunk fat percentage	0.4	1.8	5.3	2.3	1.0	-0.9	0.8	-1.0	2.0	-0.1	-1.2	1.3
Relative age voice broke	0.4	0.5	1.8	0.3	-0.4	-0.7	-1.4	-0.0	-0.0	-0.5	-0.7	-1.2
Age when periods started (menarche)	0.4	0.9	1.9	-0.4	1.4	1.3	0.2	1.1	-0.5	1.1	1.0	0.7
Hayfever, allergic rhinitis or eczema	0.4	1.0	3.0	-0.9	-0.5	-1.7	-0.8	-0.7	-0.4	-0.4	-1.7	-0.7
Multivitamins +/- minerals	0.4	0.5	1.6	0.8	0.9	-0.3	-0.5	-0.5	-0.5	-1.3	-0.2	-0.8
Medication: Atenolol	0.4	0.6	1.3	-1.0	-1.1	-0.4	-0.8	-0.1	0.4	-1.0	-0.3	-0.9
Trunk fat mass	0.4	1.8	4.5	2.1	1.3	-0.2	1.4	-0.3	2.1	0.3	-0.6	1.7
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.3	0.5	0.5	-0.8	-0.9	-0.8	0.5	-1.1	-0.6	-1.1
Forced vital capacity (FVC)	0.4	1.4	2.8	-0.3	1.0	1.5	0.9	1.7	-0.6	1.2	1.6	0.9
Weight	0.4	2.0	4.9	1.2	1.2	0.8	2.2	1.1	1.7	1.0	0.7	1.9
Falls in the last year	0.4	0.5	2.3	-0.8	-1.5	-0.1	0.4	-0.7	1.0	0.4	0.0	0.0
Number of live births	0.4	0.5	3.1	-1.8	-0.4	0.5	-0.4	0.8	-0.4	0.5	0.0	0.1
Pulse wave Arterial Stiffness index	0.4	0.5	1.4	-1.2	-0.7	0.6	0.9	0.2	0.5	0.4	0.9	0.1
Arm fat mass (right)	0.4	1.5	5.3	1.7	0.1	-1.2	0.5	-1.0	2.3	-0.3	-1.4	0.4
Medication: Paracetamol	0.4	0.6	3.1	-0.9	0.5	0.5	0.1	0.6	1.7	0.4	0.6	-0.1
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.7	-1.3	-0.3	0.2	-0.1	0.8	0.6	-0.5	0.6	-1.0
Pulse wave peak to peak time	0.4	0.4	1.7	1.2	1.3	0.0	-0.3	0.4	-0.5	-0.0	-0.2	0.4
Neck or shoulder pain in last month	0.4	0.5	0.9	0.5	0.8	-0.9	-0.7	-0.7	0.3	-1.0	-0.9	-0.3
Heart disease (mother)	0.4	0.4	0.8	-0.2	-0.4	-0.6	-0.7	-0.9	0.8	-0.8	-0.5	-0.6
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	2.2	1.5	-0.2	-0.6	-0.1	-0.4	1.0	-1.0	-0.4	-0.3
Knee pain experienced in last month	0.4	0.7	2.2	0.5	-0.5	-0.9	-0.6	-1.5	0.4	-0.4	-1.4	0.3
Hypertension (Self-reported)	0.4	1.0	5.4	-0.1	-0.8	-0.4	-0.3	-0.4	2.3	-0.6	0.1	-1.4
Breast cancer (self-reported)	0.4	0.5	1.0	0.5	0.0	0.5	0.8	0.8	1.0	1.0	0.6	0.3
Osteoarthritis (self-reported)	0.4	0.5	2.2	0.6	-1.0	-0.6	-0.4	-0.3	1.5	-0.5	-0.6	0.1
Irritability	0.4	0.7	3.6	0.6	0.7	0.7	-0.0	-0.1	1.9	-0.3	1.1	-0.4
Vascular/heart problems diagnosed by doctor	0.4	1.0	4.1	-0.3	0.6	0.7	0.6	0.8	-2.0	0.8	0.3	1.4
Impedance of whole body	0.4	1.9	4.7	-0.4	2.2	1.5	0.7	0.9	-1.9	0.8	1.2	1.7
Neuroticism (Nagel 2018)	0.3	0.6	3.7	-0.8	-0.1	0.3	-0.3	0.0	1.9	-0.5	0.6	-0.7
Worry (Nagel 2018)	0.3	0.5	2.0	-0.2	0.7	-0.4	-0.7	-0.7	0.3	-1.4	0.0	-1.0
Verbal and Numeric Reasoning (VNR)	0.3	0.8	2.5	0.5	-0.5	-0.8	-0.9	-1.2	1.6	0.6	-1.0	-0.2
HDL Cholesterol	0.3	0.5	2.1	-1.5	-1.0	0.3	-0.3	0.5	0.6	0.6	-0.1	0.0
Rheumatoid Arthritis	0.3	0.4	1.1	0.6	0.7	0.4	0.7	0.2	1.1	0.3	0.3	0.8
Relative age of first facial hair	0.3	0.5	1.1	-0.8	0.7	0.4	-0.9	0.9	1.1	0.1	0.5	-0.6
Systolic blood pressure, automated reading	0.3	0.9	3.6	-1.3	-0.9	-0.3	-0.4	-0.1	1.9	-0.1	0.0	-1.1
Maternal smoking around birth	0.3	0.4	1.1	-0.9	-0.2	0.6	0.3	0.6	1.1	0.2	0.8	0.1
High blood pressure	0.3	0.8	4.5	-0.2	-0.7	-0.4	-0.2	-0.5	2.1	-0.5	0.0	-1.3
High blood pressure (mother)	0.3	0.4	1.4	-0.1	-0.2	-0.5	-0.8	-0.8	1.2	-0.5	-0.5	-0.6
Had menopause	0.3	0.3	1.6	-0.3	-0.1	-0.5	-0.2	-0.6	1.3	-0.0	-0.6	-0.7
Financial difficulties in last 2 years	0.3	0.4	1.1	-0.4	-0.1	-0.4	-0.6	-0.6	-0.2	-1.0	-0.3	-1.0
Hip circumference	0.3	1.3	3.4	1.6	1.9	0.5	1.5	0.5	1.2	0.5	0.4	1.3
Father’s age at death	0.3	0.4	2.0	0.8	1.4	-0.4	-0.2	0.3	-0.2	0.3	-0.6	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.7	-0.8	0.4	0.6	0.3	-0.2	-0.6	0.8	0.7	0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.4	0.2	1.2	-0.2	-0.5	0.1	1.1	-0.7	-0.3	-0.6
Birth weight of first child	0.3	0.6	1.7	1.3	0.2	-0.7	-0.6	-0.8	0.8	-0.8	-0.6	-0.7
Blood clot in the leg (DVT)	0.3	0.4	0.8	-0.5	-0.7	0.3	0.9	0.3	-0.9	0.6	0.5	0.5
Headache pain in last month	0.3	0.6	1.2	0.8	-0.2	-1.0	-1.0	-0.6	0.0	-1.1	-0.7	-0.8
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.5	-0.7	-0.5	-0.6	-0.6	-0.6	0.6	-0.2	-0.2	-1.2
Exposure to tobacco smoke outside home	0.3	0.4	1.3	-1.1	0.2	0.7	0.5	1.0	0.5	0.0	0.5	-0.0
Migraine (self-reported)	0.3	0.4	2.9	1.7	0.1	-0.1	0.3	-0.3	0.1	-0.1	0.4	-0.0
Whole body fat mass	0.3	1.4	4.4	2.0	0.8	-0.4	1.2	-0.4	2.1	-0.1	-0.7	1.3
Leg fat mass (right)	0.3	1.3	5.4	1.8	0.3	-0.7	1.0	-0.6	2.3	-0.5	-0.8	0.7
Chest pain or discomfort	0.3	0.5	1.3	-0.8	-0.5	-0.6	-0.6	-0.9	0.1	-0.7	-0.6	-1.1
Family relationship satisfaction	0.3	0.4	1.6	0.1	1.3	0.5	-0.0	0.7	0.7	0.3	0.4	0.3
Commuting to job workplace: Car/motor vehicle	0.3	0.4	2.5	-0.0	0.2	-0.0	0.1	-0.1	-1.6	-0.9	-0.1	-0.2
Illnesses of siblings: Diabetes	0.3	0.3	0.9	-0.2	0.5	0.4	0.6	0.1	0.5	0.8	0.4	0.9
Loneliness, isolation	0.3	0.4	1.5	-0.9	0.7	0.3	0.3	0.3	1.2	-0.1	0.4	-0.4
Arm fat mass (left)	0.3	1.4	5.3	1.6	0.1	-1.1	0.6	-0.8	2.3	-0.2	-1.4	0.5
Miserableness	0.3	0.6	3.3	-0.8	-0.7	0.4	-0.3	0.2	1.8	0.1	0.5	-0.5
Commuting to job workplace: Public transport	0.3	0.4	1.1	-0.7	-1.0	-0.3	-0.8	0.3	0.4	0.5	-0.3	-0.7
Medication: Blood pressure	0.3	0.5	2.5	0.4	0.0	-0.4	-0.8	-0.3	1.6	-0.3	-0.6	-0.9
Medication: Lisinopril	0.3	0.3	1.1	1.0	1.0	0.1	0.5	0.0	0.2	-0.2	0.4	0.7
Fractured/broken bones in last 5 years	0.3	0.4	0.9	-0.9	0.5	0.4	0.8	0.2	0.7	0.6	0.3	0.6
Leg fat mass (left)	0.3	1.2	5.0	1.8	0.1	-0.7	1.0	-0.6	2.2	-0.4	-0.8	0.7
Depression (Nagel 2018)	0.2	0.3	1.1	0.1	0.4	0.3	0.2	0.1	1.1	0.3	1.0	-0.2
Lupus	0.2	0.3	0.7	-0.8	-0.2	-0.2	-0.1	-0.7	-0.8	-0.1	-0.6	0.4
Blood Eosinophil Count	0.2	1.4	4.5	1.9	0.3	-1.6	-1.1	-0.6	-0.4	-0.6	-2.1	0.1
Lung FVC	0.2	0.9	2.8	-1.1	-1.7	-0.6	-1.1	-0.3	1.0	0.2	-0.5	-1.3
Pack years adult smoking proportion	0.2	0.3	1.3	0.2	-0.5	-0.3	0.3	-0.5	1.1	-0.9	-0.2	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.3	1.1	0.4	1.1	0.3	0.4	0.1	0.2	-0.4	0.8	-0.4
Alcohol usually taken with meals	0.2	0.3	0.7	0.1	-0.8	0.7	0.6	0.5	-0.2	0.1	0.7	0.4
Had other major operations	0.2	0.2	0.9	0.8	0.9	-0.2	-0.1	-0.5	-0.2	-0.3	-0.3	0.1
Mouth/teeth dental problems	0.2	0.3	0.7	-0.2	-0.0	-0.3	-0.1	-0.4	-0.9	-0.8	-0.7	-0.4
Fluid intelligence score	0.2	0.5	1.4	0.6	-0.2	-0.5	-0.8	-1.0	1.2	0.5	-0.7	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.9	0.4	-0.2	-0.4	-0.1	-0.7	1.4	-0.2	-0.1	-0.3
Mouth/teeth dental problems: Dentures	0.2	0.3	1.3	-0.6	-1.2	-0.6	-0.5	-0.3	0.2	-0.1	-0.4	-0.2
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.2	0.5	-0.0	-0.4	-0.5	-0.5	-0.2	0.7	-0.5	-0.3	-0.7
Exposure to tobacco smoke at home	0.2	0.2	0.6	0.6	0.4	-0.2	-0.5	-0.2	-0.6	-0.5	0.4	-0.8
Pulse wave reflection index	0.2	0.3	1.3	-0.7	-1.2	-0.2	-0.1	-0.4	-0.0	-0.3	-0.1	-0.6
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	2.1	0.5	-0.2	-0.2	-0.2	-0.3	-1.5	0.4	-0.2	-0.2
Age at first live birth	0.2	0.3	0.8	-0.4	-0.5	0.5	0.0	0.9	0.9	0.6	0.6	-0.1
Eye problems/disorders: None of the above	0.2	0.3	0.9	-0.6	-0.5	-0.4	-0.4	0.0	0.9	0.1	-0.8	0.2
Alcohol intake frequency.	0.2	0.6	1.4	1.2	0.2	0.2	0.9	0.6	-0.5	0.9	0.4	1.1
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.2	0.9	1.0	-0.2	-0.1	0.3	-0.7	0.1	0.3	0.4	0.2
Hearing aid user	0.2	0.2	0.5	0.3	-0.7	-0.5	-0.5	-0.7	-0.1	-0.2	-0.4	-0.6
Risk taking	0.2	0.2	0.8	0.9	0.3	-0.4	-0.3	-0.7	0.7	0.0	-0.3	-0.3
Pain experienced in last month	0.2	0.3	0.9	-0.9	-0.6	0.4	0.1	0.5	-0.5	0.2	0.4	-0.8
Alcohol drinker status: Previous	0.2	0.2	0.9	0.9	0.1	-0.0	0.0	0.6	-0.4	-0.1	0.3	-0.3
Intelligence (Savage-Jansen 2018)	0.1	0.3	0.6	0.3	-0.3	-0.2	-0.7	-0.5	0.8	0.6	-0.7	-0.1
Ovarian Cancer	0.1	0.1	0.1	-0.0	-0.4	0.3	0.3	0.2	-0.1	-0.4	0.4	-0.0
Body Mass Index (BMI) (2010)	0.1	0.1	0.5	0.1	-0.2	0.0	0.2	0.7	0.1	-0.2	0.0	0.4
LDL Cholesterol	0.1	0.1	0.6	-0.5	-0.3	0.1	0.3	0.1	0.8	0.1	-0.0	0.4
Primary Biliary Cirrhosis	0.1	0.1	1.1	-0.2	-1.0	-0.1	0.0	-0.1	0.1	-0.2	-0.0	-0.4
Blood White Count	0.1	0.9	2.9	1.0	1.3	0.1	0.8	0.2	-1.7	-0.1	0.0	1.2
Neuroticism	0.1	0.3	1.0	-0.7	0.3	0.4	-0.0	0.0	1.0	-0.2	0.8	-0.4
Medication: Ramipril	0.1	0.1	0.3	-0.3	-0.4	-0.2	-0.1	0.1	-0.5	-0.1	-0.4	-0.2
Neuroticism score	0.1	0.2	0.8	-0.9	-0.4	0.1	-0.2	-0.1	0.8	0.4	0.5	-0.3
Impedance of arm (right)	0.1	0.5	2.5	-0.0	1.6	0.3	-0.2	-0.2	-1.1	0.5	-0.0	0.7
Noisy workplace	0.1	0.1	0.3	0.0	-0.0	0.3	0.1	0.3	0.3	0.4	0.6	0.3
Qualifications: A levels/AS levels or equivalent	0.1	0.3	0.7	-0.1	-0.8	-0.3	-0.6	-0.1	-0.6	0.9	-0.3	-0.2
Medication: Lansoprazole	0.1	0.1	0.7	0.8	0.3	-0.1	-0.1	0.0	-0.1	-0.2	0.0	-0.4
Impedance of arm (left)	0.1	0.6	1.6	-0.2	1.3	0.6	-0.0	0.1	-1.2	0.8	0.3	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.5	0.1	0.4	-0.3	-0.3	-0.3	-0.2	-0.3	-0.7	-0.1
Suffer from ‘nerves’	0.1	0.1	0.4	0.0	0.3	-0.6	-0.3	-0.3	-0.1	-0.4	-0.2	-0.5
Had major operations	0.1	0.1	0.2	-0.5	0.0	0.1	0.0	-0.1	0.4	-0.0	-0.3	0.2
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.6	0.2	0.1	0.1	-0.3	0.4	0.8	0.5	-0.3	0.5
Diastolic blood pressure, automated reading	0.1	0.3	0.8	-0.9	-0.2	0.4	0.4	0.0	0.2	0.5	0.9	-0.5
Basal cell carcinoma (self-reported)	0.1	0.1	0.3	0.5	0.1	-0.5	-0.2	-0.4	-0.2	-0.6	-0.3	-0.0
Hair Pigment	0.0	0.3	1.6	1.3	0.8	-0.2	0.1	0.2	0.1	-0.3	-0.0	-0.4
Pulse rate, automated reading	0.0	0.1	0.3	0.1	-0.1	0.3	0.5	-0.4	0.3	-0.2	0.4	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.1	0.3	0.5	-0.4	-0.0	0.3	0.1	-0.1	0.4	0.0	0.4

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SYTL2

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