Best TWAS P=2.27e-09 · Best GWAS P=3.72e-11 conditioned to 0.00061
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | CRYL1 | 0.27 | 0.00 | lasso | 11 | 0.00 | 3.4e-01 | -3.2 | -5.4 | 7.2e-08 | -0.64 | 0.05 | 0.42 | FALSE |
| 2 | YFS | Blood | IL17D | 0.02 | 0.02 | blup | 482 | 0.01 | 1.8e-04 | -3.2 | -5.2 | 2.3e-07 | -0.44 | 0.64 | 0.13 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | IFT88 | 0.04 | 0.03 | blup | 83 | 0.03 | 2.2e-04 | 4.6 | 6.0 | 2.3e-09 | 0.69 | 0.01 | 0.91 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | IFT88 | 0.11 | 0.10 | blup | 86 | 0.09 | 3.5e-10 | 4.7 | 5.6 | 2.2e-08 | 0.70 | 0.01 | 0.97 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | IFT88 | 0.05 | 0.00 | blup | 85 | 0.02 | 2.1e-03 | 3.7 | 5.6 | 2.5e-08 | 0.59 | 0.01 | 0.42 | FALSE |