TWAS hub - CRYL1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1450	0.0370	6.7e-06	0.019	0.047	0.040	0.053	0.028	2.1e-03	1.9e-06	1.1e-05	4.4e-07	2.0e-04
2	GTEx	Adipose Subcutaneous	0.3590	0.0750	3.9e-06	0.011	NA	0.024	NA	0.037	3.8e-02	NA	4.1e-03	NA	5.0e-04
3	GTEx	Adipose Visceral Omentum	0.1720	0.0760	9.8e-03	0.003	NA	-0.005	NA	-0.005	2.3e-01	NA	9.2e-01	NA	9.5e-01
4	GTEx	Brain Cerebellum	0.2770	0.0910	3.3e-03	-0.006	NA	-0.009	NA	-0.010	5.5e-01	NA	7.4e-01	NA	9.9e-01
5	GTEx	Cells EBV-transformed lymphocytes	0.2730	0.0970	6.2e-03	0.000	NA	-0.008	NA	-0.001	3.3e-01	NA	7.4e-01	NA	3.4e-01
6	GTEx	Esophagus Mucosa	0.4040	0.0560	2.5e-11	0.226	NA	0.220	NA	0.248	3.6e-15	NA	9.0e-15	NA	1.2e-16
7	GTEx	Nerve Tibial	0.1936	0.0588	6.6e-04	0.095	NA	0.107	NA	0.105	3.2e-07	NA	5.5e-08	NA	7.0e-08
8	GTEx	Skin Not Sun Exposed Suprapubic	0.4370	0.0820	6.6e-07	0.064	NA	0.111	NA	0.111	2.2e-04	NA	1.2e-06	NA	1.1e-06
9	GTEx	Skin Sun Exposed Lower leg	0.1670	0.0530	1.0e-03	0.075	NA	0.089	NA	0.123	8.4e-07	NA	7.9e-08	NA	2.4e-10
10	GTEx	Stomach	0.2200	0.0740	1.9e-03	-0.006	NA	0.028	NA	0.020	9.2e-01	NA	1.7e-02	NA	3.6e-02
11	GTEx	Thyroid	0.2130	0.0530	1.6e-05	0.018	NA	0.087	NA	0.051	1.4e-02	NA	3.2e-07	NA	9.5e-05
12	YFS	Blood	0.0757	0.0202	1.0e-07	0.031	0.029	0.048	0.043	0.043	1.4e-10	5.3e-10	2.0e-15	5.0e-14	4.3e-14
13	TCGA	Breast Invasive Carcinoma	0.0364	0.0126	3.0e-05	0.017	0.030	0.018	NA	0.018	1.4e-04	6.4e-07	8.4e-05	NA	9.7e-05
14	TCGA	Head and Neck Squamous Cell Carcinoma	0.0461	0.0195	2.4e-03	0.040	0.024	0.020	NA	0.024	2.3e-05	9.0e-04	2.3e-03	NA	9.8e-04
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0549	0.0265	9.8e-03	-0.001	-0.002	0.007	NA	0.007	4.5e-01	5.6e-01	4.3e-02	NA	5.3e-02
16	TCGA	Lung Squamous Cell Carcinoma	0.0536	0.0207	8.1e-04	0.013	0.028	0.025	NA	0.020	1.0e-02	3.2e-04	7.0e-04	NA	2.4e-03
17	TCGA	Thyroid Carcinoma	0.1130	0.0410	2.8e-04	0.045	0.038	0.049	NA	0.041	3.3e-05	1.4e-04	1.4e-05	NA	6.8e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Commuting to job workplace: Car/motor vehicle	5.6	6.5	14.7	0.9	2.8	1.1	-0.4	2.0	3.6	3.0	3.5	2.8	1.4	-0.0	3.8	3.3	3.3	0.2	3.8	-0.6
Alzheimer’s Disease (in father)	3.7	4.0	11.7	2.4	3.4	0.4	0.5	1.3	3.3	2.8	2.7	1.6	-0.1	0.2	2.6	1.3	2.6	0.3	2.2	-0.4
Medication: Ibuprofen	3.5	4.2	11.6	-2.9	-1.0	-0.9	1.0	-3.4	-2.6	-2.6	-2.0	-0.8	-2.6	-1.1	-2.5	-2.1	-2.1	-0.7	-2.1	-1.6
Ovarian Cancer	2.7	3.5	8.4	-0.8	-1.6	-2.5	0.0	-0.3	-2.3	-1.9	-2.5	-2.3	0.1	-0.2	-2.4	-2.9	-2.7	0.6	-2.8	0.3
Townsend deprivation index at recruitment	2.7	3.7	10.4	-0.0	-1.6	-0.4	-0.7	-2.1	-2.4	-2.0	-2.6	-2.6	-1.2	0.0	-1.6	-3.2	-2.9	-0.7	-3.0	0.1
Lupus	2.6	3.9	9.6	1.1	3.0	0.8	-0.9	1.2	2.2	2.8	2.0	0.8	2.3	2.0	2.3	2.2	2.3	0.3	1.3	3.1
Diabetes diagnosed by doctor	2.6	4.3	8.7	-1.9	-1.9	-0.7	1.8	0.6	-3.0	-1.9	-2.3	-1.5	-1.0	-1.7	-2.1	-2.6	-2.9	2.1	-2.9	-2.3
Pack years adult smoking proportion	2.5	3.8	11.4	-0.7	-1.9	-1.2	1.6	-1.9	-3.4	-2.6	-1.7	-0.1	-2.4	-2.7	-1.7	-2.2	-1.8	0.1	-1.5	-2.5
Diabetes (self-reported)	2.5	3.8	8.4	-2.1	-1.9	-0.3	2.2	0.5	-2.9	-1.9	-2.2	-1.3	-0.7	-1.5	-1.7	-2.0	-2.6	2.4	-2.5	-2.1
Pack years of smoking	2.4	3.5	11.1	-0.4	-1.7	-1.6	1.8	-1.8	-3.3	-2.4	-1.8	-0.2	-2.0	-2.5	-1.4	-2.0	-1.7	0.5	-1.6	-2.2
Diverticular disease/diverticulitis (self-reported)	2.3	2.7	6.6	-0.4	2.5	1.0	1.1	2.0	2.2	1.9	2.0	0.7	1.4	1.2	1.9	1.3	1.8	2.6	1.2	0.5
Exposure to tobacco smoke outside home	2.3	3.0	6.8	2.0	1.3	2.4	-0.7	-0.3	1.5	1.6	1.6	0.9	1.2	1.7	1.4	2.5	2.3	-0.6	2.5	2.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.2	2.6	7.4	0.6	2.2	1.4	0.2	0.7	2.2	1.4	1.8	1.3	1.2	0.8	2.7	2.3	1.7	-1.2	2.0	1.3
Wears glasses or contact lenses	2.2	2.5	7.6	0.3	1.5	1.7	1.2	0.9	1.6	1.7	2.1	2.3	1.2	-0.4	0.5	2.7	2.2	1.0	2.1	0.9
Age at last live birth	2.0	2.9	10.3	-1.0	-1.5	-2.6	-0.4	-2.3	-1.7	-1.4	-1.6	-0.9	-0.7	-1.0	-3.2	-2.2	-2.1	-1.3	-1.6	-0.5
Commuting to job workplace: Walk	2.0	2.1	5.0	0.7	-1.6	-0.1	1.2	-0.2	-1.8	-1.3	-2.0	-2.0	-0.4	0.2	-2.1	-1.6	-2.2	1.2	-2.2	0.2
Type 2 Diabetes (T2D) (2018)	1.9	3.6	7.9	-1.4	-1.5	-0.4	2.1	1.0	-2.5	-1.8	-2.3	-2.2	-0.7	-0.7	-1.5	-2.6	-2.8	2.2	-2.8	-1.3
Hayfever/allergic rhinitis (self-reported)	1.9	2.5	16.8	-0.3	-1.6	-1.9	-2.0	-1.0	-0.5	-1.6	0.2	1.3	-1.8	-4.1	-1.2	-0.2	-0.3	-0.5	0.3	-2.3
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.2	8.3	-1.0	1.4	1.1	-0.5	2.7	2.3	0.7	1.2	0.6	0.1	-0.3	2.9	1.1	1.4	-1.5	1.7	-0.9
Ever had bowel cancer screening	1.8	2.1	6.2	1.8	2.5	1.2	0.1	1.6	1.7	1.9	1.9	0.5	1.2	0.5	2.1	1.5	1.4	0.6	0.9	0.9
Fasting Glucose	1.7	2.1	8.0	1.1	1.4	0.5	-0.2	0.4	1.4	0.0	2.3	2.8	0.9	-0.9	-0.1	1.4	2.7	0.5	1.9	-1.2
Had menopause	1.7	2.2	7.4	0.6	1.4	0.8	-0.3	0.3	1.2	1.8	0.7	-0.1	2.5	2.5	0.7	1.6	1.6	1.3	1.1	2.7
Had major operations	1.7	2.0	6.4	-1.0	1.4	1.7	0.8	2.5	1.4	1.4	1.2	0.5	1.1	2.2	1.6	1.3	1.0	-0.8	1.5	0.7
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.0	6.2	-1.9	-0.9	-0.7	0.5	-2.5	-1.9	-1.6	-1.5	-0.9	-1.8	-0.6	-1.3	-1.2	-1.4	-1.3	-1.2	-1.0
Asthma (self-reported)	1.6	3.2	6.4	-2.1	-2.0	-2.0	-0.1	-1.0	-1.8	-1.8	-1.1	-1.0	-2.5	-2.1	-1.5	-2.4	-2.3	0.3	-1.3	-2.5
Vitamin and mineral supplements	1.5	2.1	8.4	-2.9	-2.2	-0.5	0.8	-1.1	-0.9	-1.3	-1.3	-0.4	-1.5	-1.4	-1.0	-0.3	-1.9	-1.5	-1.2	-1.9
Serious illness, injury or assault to yourself	1.5	1.9	6.0	0.1	-1.9	0.3	1.3	0.6	-1.9	-1.2	-2.0	-1.4	1.0	2.4	-2.0	-1.5	-0.5	0.4	-0.8	0.7
Asthma	1.5	3.0	5.8	-2.0	-2.1	-2.1	-0.2	-0.9	-1.7	-1.7	-1.1	-1.0	-2.3	-2.1	-1.4	-2.3	-2.3	0.0	-1.3	-2.4
Chronic bronchitis/emphysema (mother)	1.5	1.8	4.9	-0.5	0.1	-0.7	1.8	-0.1	-0.7	0.1	-1.4	-2.2	2.2	2.2	0.4	-0.6	-1.1	1.3	-1.4	2.0
Number of full sisters	1.5	1.8	5.7	-1.5	-0.9	0.8	0.4	-1.0	-1.6	-1.4	-1.6	-1.4	-1.0	0.1	-1.3	-1.9	-2.0	0.5	-2.4	-0.4
Suffer from ‘nerves’	1.5	2.3	12.7	-0.1	-0.6	3.6	-0.8	1.6	0.9	0.4	0.3	0.0	1.3	2.0	1.2	1.9	0.9	-2.1	1.7	1.7
Supplements: Vitamin C	1.5	1.8	6.9	1.1	2.6	0.4	0.4	1.0	0.6	1.2	1.0	0.2	2.0	1.9	0.9	0.7	1.1	2.3	0.3	1.8
Smoking status: Previous	1.5	2.2	8.3	-2.3	0.7	1.8	1.3	2.9	-0.5	0.3	-0.8	-1.9	0.5	1.2	0.5	-0.5	-0.9	2.5	-1.7	1.1
Osteoarthritis (self-reported)	1.5	1.9	6.0	-0.8	0.9	0.4	0.3	-0.5	-1.2	-0.2	-1.3	-2.3	-0.0	1.8	0.1	-1.4	-1.5	2.5	-2.3	1.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.1	7.7	0.6	2.7	0.6	-2.8	1.2	2.7	2.1	2.3	1.5	1.6	0.7	0.9	1.7	2.1	0.4	1.6	1.8
Medication: Paracetamol	1.5	2.3	4.6	-1.9	-1.6	1.5	-0.5	-1.8	-2.0	-1.7	-1.9	-1.1	0.2	0.2	-2.0	-1.4	-1.5	-1.2	-2.1	1.0
Commuting to job workplace: Cycle	1.5	1.8	6.9	-0.1	-0.6	-0.5	-0.8	-1.2	-1.2	-1.3	-1.3	-1.2	0.4	0.4	-2.6	-1.3	-1.8	0.6	-2.4	1.7
Ulcerative Colitis	1.4	2.0	6.6	0.1	0.1	-1.9	2.2	0.1	-0.8	0.9	-1.3	-2.6	-0.9	0.5	-0.9	-1.9	-1.5	1.2	-2.4	0.4
Hypothyroidism (self reported)	1.4	3.1	8.8	-0.6	-3.0	-0.1	-1.2	-1.1	-2.5	-2.3	-2.5	-1.7	-0.6	-1.5	-2.2	-1.9	-2.2	0.2	-1.9	-0.4
Qualifications: CSEs or equivalent	1.4	1.9	4.1	-0.7	-1.7	-0.4	-0.4	-0.9	-1.4	-1.6	-1.1	-0.5	-0.8	-2.0	-0.9	-2.0	-2.0	-1.7	-1.2	-1.8
Noisy workplace	1.4	1.8	7.7	-0.1	-0.5	-0.4	-0.7	-1.7	-1.5	-0.7	-1.6	-2.2	0.5	0.8	-0.4	-1.2	-2.8	1.3	-1.5	1.4
Prospective memory result	1.4	1.8	4.9	0.1	-1.2	-2.2	1.0	-0.4	-1.7	-1.0	-1.5	-1.7	0.0	1.1	-1.0	-1.6	-1.7	-1.2	-1.9	0.7
Osteoporosis (self-reported)	1.4	1.7	5.6	0.8	1.2	1.2	-0.8	1.3	0.7	1.0	0.8	0.8	2.0	1.7	-0.1	1.9	1.2	1.2	1.1	2.4
Ever had prostate specific antigen (PSA) test	1.4	1.6	5.4	0.6	1.6	1.6	-0.5	0.8	1.0	0.1	1.0	1.1	2.3	0.2	0.8	2.0	1.3	1.4	1.3	1.4
Hand grip strength (left)	1.3	3.4	22.2	-2.2	-0.7	0.4	-1.3	-4.7	-1.0	-1.1	-1.1	-1.7	-1.9	-1.7	-1.4	-1.5	-2.4	-2.0	-1.7	-0.1
Hand grip strength (right)	1.3	3.4	28.5	-0.4	-0.8	0.5	-1.8	-5.3	-0.9	-1.2	-1.1	-1.3	-1.7	-1.8	-1.4	-1.1	-1.5	-2.8	-0.9	0.2
Bilateral oophorectomy (both ovaries removed)	1.3	1.4	4.7	2.0	1.8	0.4	1.1	-0.2	0.9	2.0	0.6	-0.9	1.3	1.7	0.6	0.3	0.5	0.4	-0.2	2.2
Medication: Amlodipine	1.3	1.9	6.8	-0.2	0.9	-0.3	-0.2	2.1	1.0	1.6	0.5	-1.0	2.6	2.2	2.2	1.2	0.6	0.5	0.2	1.7
Friendships satisfaction	1.3	1.6	4.4	0.7	-1.2	-0.2	-0.7	0.1	-1.6	-2.0	-1.9	-1.8	-0.7	0.7	-0.8	-2.1	-1.8	-0.5	-1.4	-0.4
Irritability	1.3	2.2	5.6	1.0	0.8	0.7	-0.2	0.8	1.7	1.3	1.8	1.7	0.9	1.1	1.7	1.9	2.1	-2.0	2.4	1.2
Diastolic blood pressure, automated reading	1.3	4.0	8.6	1.8	2.3	1.4	0.5	1.8	2.8	2.3	2.4	1.5	0.2	1.2	2.9	1.8	2.8	2.5	2.0	0.9
Intelligence (Savage-Jansen 2018)	1.2	3.6	14.9	0.7	2.0	-0.5	-0.6	2.6	2.4	3.9	1.7	-0.0	2.6	1.0	1.2	2.1	1.8	-0.2	1.8	2.3
Alzheimer’s Disease (including proxy)	1.2	1.8	4.8	1.6	1.6	-0.7	-1.6	0.6	2.2	1.7	1.8	0.8	0.7	-0.1	1.9	0.9	1.5	-0.2	1.7	0.3
Hayfever, allergic rhinitis or eczema	1.2	2.6	13.6	-1.9	-3.7	-0.4	-0.6	0.5	-1.9	-1.8	-1.8	-0.8	-0.9	-2.1	-1.3	-1.7	-1.5	-0.3	-0.4	-1.8
Past tobacco smoking	1.2	2.2	6.7	2.4	-0.2	-1.7	-0.5	-1.8	1.0	-0.4	1.2	2.6	-0.6	-1.3	-0.2	0.6	1.5	-2.3	2.1	-1.1
Qualifications: None of the above	1.2	2.6	6.8	1.3	2.3	2.1	2.5	-0.6	1.0	1.8	1.3	0.2	1.5	2.6	0.5	1.6	1.7	1.0	1.0	1.9
Hair/balding pattern: Pattern 4	1.2	2.9	6.6	-2.1	-2.2	-1.9	1.6	-1.2	-2.1	-1.4	-2.0	-1.2	-1.1	-0.2	-2.6	-1.6	-2.2	0.2	-2.1	0.0
Age at first live birth	1.2	2.1	9.5	-1.5	-1.5	-3.1	-0.8	-1.7	-0.9	-1.4	-1.4	-0.4	-1.3	-0.9	-1.9	-1.5	-1.8	-0.5	-1.2	-1.0
Family relationship satisfaction	1.2	1.5	4.2	0.4	-1.3	-0.8	-0.2	-0.4	-1.4	-1.6	-1.8	-1.8	-0.2	0.8	-1.2	-1.3	-2.1	-1.1	-1.5	0.4
Medication: Aspirin	1.2	1.5	5.2	-0.1	-0.9	0.2	1.8	-1.3	-2.3	-0.5	-1.7	-1.5	0.0	-0.6	-1.5	-1.3	-1.8	0.7	-1.1	0.2
Angina	1.1	1.4	3.9	-0.6	-1.1	1.3	1.9	-1.0	-1.1	0.6	-1.3	-2.0	0.4	1.7	-0.2	-0.6	-1.0	0.7	-1.0	1.7
Alcohol usually taken with meals	1.1	1.8	3.8	1.3	1.8	1.3	-0.5	-0.2	1.9	1.0	1.9	2.0	1.5	0.2	0.7	1.3	1.9	0.6	1.5	0.8
Happiness	1.1	1.4	5.1	0.1	-0.6	2.3	0.2	-0.0	-1.2	-1.3	-1.3	-1.3	-1.0	0.7	-0.9	-1.1	-2.2	-0.4	-1.6	0.1
Medication: Paracetamol	1.1	1.8	4.1	-1.6	-1.5	2.0	-1.0	-1.1	-1.8	-1.2	-1.6	-1.0	-0.1	0.1	-1.3	-1.5	-1.4	-0.8	-1.9	0.8
Health satisfaction	1.1	1.4	9.8	0.4	0.0	1.1	3.1	1.0	-0.5	-0.4	-0.7	-0.7	0.6	1.9	0.5	-0.6	-0.9	2.0	-0.5	1.0
Mouth/teeth dental problems: Loose teeth	1.1	1.3	4.7	-0.8	0.1	0.5	1.1	-1.1	-1.0	0.6	-0.9	-1.5	0.1	-0.4	-1.0	-1.4	-1.7	1.7	-2.2	0.0
Financial situation satisfaction	1.1	1.3	3.4	-0.5	-1.2	0.3	1.5	-1.1	-1.6	-0.8	-1.9	-1.6	-0.2	0.9	-0.5	-1.2	-1.7	-1.5	-0.6	0.9
Tinnitus: Yes, now most or all of the time	1.1	1.3	4.6	-2.1	-0.1	-1.3	-1.3	-0.9	0.2	1.7	0.6	-0.0	1.0	-1.0	0.8	1.5	0.7	1.2	1.5	1.4
Pain type(s) experienced in last month: Hip pain	1.1	1.4	5.8	0.7	0.2	-0.5	0.7	-2.4	-2.1	-0.1	-1.1	-0.9	0.1	0.4	-1.1	-1.6	-1.5	-0.9	-0.9	1.3
HbA1C	1.0	1.1	4.3	-2.1	-0.7	-2.0	1.0	-1.0	-0.4	-1.1	-0.8	-0.5	-0.5	-0.5	0.1	-1.1	-1.0	1.4	-0.6	-0.1
Supplements: Zinc	1.0	1.1	3.5	1.1	1.9	-0.4	-1.0	0.8	0.5	-0.6	1.1	1.7	-1.4	-1.5	-0.1	0.5	1.2	0.7	0.2	-1.1
Supplements: Glucosamine	1.0	1.4	5.8	0.8	1.5	-0.1	0.9	-0.5	0.2	1.7	0.8	0.5	2.4	0.3	0.3	1.7	1.1	1.0	1.1	1.8
Hearing difficulty/problems with background noise	1.0	1.6	3.2	1.0	1.5	-0.8	1.1	1.0	1.3	1.6	1.4	0.6	1.7	1.0	1.3	1.6	1.3	1.4	1.8	0.3
Allergy	1.0	2.3	9.1	2.6	3.0	0.6	0.4	-0.2	1.8	1.5	1.4	0.8	1.4	1.3	1.2	1.8	1.8	0.4	0.6	1.6
Tense / ‘highly strung’	1.0	1.6	6.3	0.5	0.7	1.7	0.5	0.6	1.2	0.6	1.4	1.4	0.3	0.4	1.5	1.2	1.6	-2.5	1.9	0.8
Angina (self-reported)	1.0	1.3	3.6	-0.6	-1.0	1.3	1.8	-1.2	-1.0	0.8	-1.2	-1.9	0.6	1.6	-0.2	-0.5	-0.9	0.5	-0.9	1.8
Illnesses of father: Heart disease	1.0	1.5	6.6	1.4	0.1	0.8	1.3	0.5	0.3	0.8	0.1	-0.7	2.3	2.6	-0.0	0.8	0.5	1.6	0.2	1.9
Handedness (chirality/laterality): Left-handed	1.0	1.2	2.9	-0.0	1.0	-0.9	-1.2	1.6	1.2	0.6	1.4	1.7	-0.1	-1.4	1.6	0.8	0.7	-0.3	1.1	-1.2
Number of operations (self-reported)	1.0	1.5	9.6	-0.2	0.7	0.4	-0.0	1.3	1.1	0.9	0.2	-1.0	1.7	3.1	1.3	1.0	0.3	0.3	0.3	2.3
Unable to work because of sickness or disability	1.0	1.3	7.4	0.0	1.3	0.9	0.2	1.1	1.0	0.9	0.9	0.7	-0.6	1.4	2.7	1.2	1.2	-0.6	1.5	-0.5
Schizophrenia vs Biploar Disorder	0.9	1.1	4.7	-0.4	0.0	0.4	-0.6	-1.9	-1.2	-0.6	0.2	1.2	-0.5	-2.2	-1.9	-1.0	0.2	-0.9	0.1	-1.3
Ulcerative Colitis (UC)	0.9	1.7	5.8	-0.9	-0.6	-0.4	1.5	0.2	-1.1	-0.8	-1.5	-1.4	-1.7	-0.6	-0.6	-2.4	-1.3	0.6	-2.0	-1.8
Frequency of depressed mood in last 2 weeks	0.9	1.3	8.9	0.8	-0.2	1.5	0.7	-0.9	-1.1	-0.7	-0.7	-0.2	-1.7	-0.5	0.2	-1.3	-0.8	-3.0	0.0	-1.2
Average weekly fortified wine intake	0.9	1.0	5.5	-0.1	-0.6	-1.0	-0.2	-2.4	-0.6	-1.6	-0.5	0.0	-0.3	-0.7	-0.9	-1.2	-0.8	-1.3	-0.9	-1.2
Illnesses of siblings	0.9	1.2	4.0	-1.6	-1.6	-0.2	0.0	-0.5	-1.2	0.0	-1.9	-2.0	0.8	-0.1	-1.3	-0.4	-1.4	-0.5	-1.1	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	5.0	-1.0	-1.5	-0.0	1.1	-1.3	-1.5	-0.9	-1.7	-1.7	-0.4	0.3	-0.2	-1.6	-1.4	-2.2	-0.9	-0.2
Falls in the last year	0.9	1.3	3.5	-0.8	-0.7	-1.9	0.9	0.7	-1.6	-0.4	-1.3	-1.3	0.5	1.0	-1.2	-1.2	-1.2	1.6	-1.1	0.1
Forced expiratory volume in 1-second (FEV1)	0.9	2.9	15.1	0.7	2.3	0.2	-3.9	-1.2	2.3	2.4	2.3	1.3	0.0	-1.8	0.1	0.4	1.2	-1.9	1.0	0.2
Shortness of breath walking on level ground	0.9	1.0	3.2	0.6	0.2	0.5	0.2	1.5	-0.4	0.8	-0.4	-0.8	1.6	1.5	1.2	0.8	-0.2	1.8	0.4	1.7
Migraine (self-reported)	0.9	1.2	2.7	-1.6	-0.5	-0.1	-1.1	0.1	-0.8	-0.8	-1.3	-1.5	-1.6	0.8	0.4	-1.1	-1.6	0.2	-1.6	-0.7
Mineral and other dietary supplements	0.9	1.3	3.7	-0.9	-1.9	0.1	1.0	-0.1	-0.8	-1.7	-1.0	-0.2	-1.7	-0.6	-0.6	-0.8	-1.3	-1.0	-0.9	-1.9
Hearing aid user	0.9	1.0	4.9	-1.0	0.8	0.9	-0.6	1.1	0.4	1.8	0.7	0.3	0.4	2.2	0.6	0.9	0.5	1.2	0.2	1.0
Supplements: Fish oil (including cod liver oil)	0.9	1.2	4.2	0.8	1.9	0.5	-1.2	-0.3	1.0	1.4	1.3	0.4	1.3	0.5	-0.0	1.2	0.9	1.2	0.5	2.0
Ever smoked	0.9	1.6	4.9	-2.0	-0.3	1.4	-0.5	1.0	-1.4	-0.1	-1.4	-2.2	-0.5	0.5	-0.1	-0.8	-1.5	1.9	-2.0	-0.0
Fractured/broken bones in last 5 years	0.9	1.2	10.5	1.6	0.5	-0.5	-3.2	-1.2	0.0	0.8	0.9	0.7	-0.4	-0.1	-1.0	0.3	-0.2	-1.4	0.2	0.1
Basal cell carcinoma (self-reported)	0.9	1.1	3.0	-0.1	0.3	1.1	-1.3	-1.6	0.1	-1.4	0.8	1.7	-0.7	-1.4	0.1	0.2	1.1	-0.8	1.2	-1.5
Heart disease (siblings)	0.9	1.1	3.5	0.5	1.5	0.3	-0.1	0.9	1.2	0.9	1.7	1.7	0.8	-0.7	0.6	0.5	1.2	-0.3	1.9	-0.8
Neuroticism (2016)	0.8	1.1	4.5	-0.1	-1.6	0.1	2.1	0.5	-1.2	-0.1	-1.4	-1.4	-0.3	1.6	-0.0	-0.2	-1.5	0.1	-0.9	1.0
Allergy or Eczema	0.8	2.2	9.3	-2.3	-3.0	-0.3	-0.7	1.0	-1.8	-1.8	-1.4	-0.4	-0.9	-1.7	-1.5	-1.2	-1.3	0.1	-0.1	-1.7
Cardiovascular Disease	0.8	2.5	6.3	1.1	2.2	0.2	1.5	2.4	1.9	2.2	1.9	0.5	0.7	0.5	2.5	1.3	1.7	2.0	0.7	0.3
Respiratory disease	0.8	1.7	4.5	-2.1	-1.5	-0.6	-0.2	-1.1	-1.5	-1.3	-0.6	-0.7	-1.6	-1.7	-1.6	-1.4	-1.5	0.0	-0.6	-1.8
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	2.5	-0.3	-0.1	-1.2	0.1	0.1	-1.1	-0.9	-0.5	-0.5	-1.6	-0.7	-1.1	-1.3	-0.4	1.3	-1.3	-1.5
Stomach or abdominal pain in last month	0.8	1.0	3.4	-1.7	0.2	0.9	1.3	0.7	-0.7	-0.5	-1.0	-1.5	0.9	1.1	0.7	-0.5	-1.3	0.5	-0.6	1.8
Financial difficulties in last 2 years	0.8	1.1	2.8	0.1	-0.8	0.4	0.1	-1.5	-1.4	-0.9	-1.0	-1.0	-1.1	-0.9	-0.3	-1.7	-1.4	-0.9	-1.5	-0.7
Time employed in main current job	0.8	0.9	4.0	1.3	0.3	0.5	0.9	-0.1	1.0	-0.5	1.3	2.0	-0.8	-0.1	0.6	1.2	1.3	-0.0	1.1	-0.3
Worrier / anxious feelings	0.8	1.4	6.1	-0.1	0.8	2.5	0.2	1.4	0.9	0.1	1.4	1.3	0.2	0.2	1.8	0.6	0.8	-1.9	1.9	-0.5
Medication: Cholesterol lowering	0.8	1.3	8.3	-1.1	0.2	2.9	0.3	1.1	0.1	1.7	0.6	0.0	2.0	-0.4	0.4	1.1	0.5	1.0	0.7	1.0
Number of full brothers	0.8	1.1	4.6	0.4	1.3	2.1	0.8	-0.9	0.6	0.5	0.9	0.8	0.8	0.3	1.9	0.8	1.3	-0.7	1.0	0.3
Medication: Seretide 50 evohaler	0.8	0.9	3.0	-0.3	-0.4	0.6	1.7	0.3	-1.5	-0.8	-0.7	-0.9	0.4	0.5	-1.2	-1.0	-0.8	1.7	-0.6	-0.4
Overall health rating	0.8	1.7	11.2	-0.4	-0.6	1.9	3.3	1.0	-0.9	-0.1	-0.9	-1.0	1.2	2.1	1.0	-0.3	-0.5	1.3	-0.3	1.3
Leg pain on walking	0.8	1.1	5.1	2.3	0.2	0.7	0.9	0.2	-0.0	0.4	0.4	-0.2	1.9	1.2	-0.8	0.0	0.5	1.0	-0.2	2.1
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	2.8	-0.4	-1.4	0.2	-0.5	-1.2	-1.1	-1.3	-0.4	0.5	-1.6	-1.7	-0.8	0.1	-1.1	-0.8	0.5	-1.2
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.8	9.7	0.6	-0.1	-0.2	-1.2	-3.1	0.5	0.0	0.7	1.0	-1.3	-2.8	-0.3	-0.2	0.1	-1.8	0.8	-1.7
Long-standing illness, disability or infirmity	0.8	1.1	5.1	-0.4	0.4	0.8	1.2	1.1	-0.8	1.3	-0.7	-1.6	0.8	2.3	0.8	0.2	-0.7	0.9	-0.6	1.5
Mouth/teeth dental problems: Mouth ulcers	0.8	1.2	4.8	-0.8	0.7	1.4	1.5	1.4	1.1	0.4	0.2	-0.3	0.8	1.3	1.3	0.4	0.8	1.0	1.1	2.2
Medication for cholesterol	0.8	1.2	4.6	-0.3	-0.1	1.5	-1.9	-0.2	0.4	0.7	-0.1	-0.4	1.7	1.0	-0.0	1.5	0.2	-2.1	1.2	1.0
Back pain experienced in last month	0.8	1.1	3.8	-0.7	-0.7	0.5	0.8	-0.1	-1.4	0.1	-1.2	-2.0	1.6	0.2	-1.0	-1.3	-0.6	-0.3	-1.0	1.8
Ever taken oral contraceptive pill	0.8	0.9	4.6	-0.5	1.6	-1.1	-2.2	-0.3	0.6	0.5	1.1	0.9	-0.1	-1.2	-0.9	-0.2	1.1	0.2	-0.0	-1.0
Medication: Atorvastatin	0.8	1.0	4.0	-0.0	1.2	1.5	-0.2	1.0	0.7	2.0	0.6	-0.5	1.4	0.9	1.1	0.5	0.2	1.0	-0.2	1.3
Myopia	0.8	1.1	3.5	-0.7	-0.6	-1.1	-0.5	1.9	-0.8	-0.8	-0.8	-0.3	-0.9	-1.3	-0.2	-1.3	-1.7	0.6	-1.3	-1.6
Vascular/heart problems diagnosed by doctor	0.8	2.1	12.2	1.3	-0.7	0.6	-2.5	-2.4	-0.1	-1.1	0.2	1.3	-0.4	-1.2	-1.9	0.4	0.3	-3.5	0.7	-0.7
Breast Cancer	0.7	1.6	6.6	-1.1	-2.0	-2.6	-1.2	1.5	-0.8	-1.2	-0.6	-0.0	-1.0	-1.7	-0.4	-0.9	-0.8	0.6	-0.6	-1.6
Age at First Birth	0.7	1.0	3.5	-1.9	1.0	-1.3	-0.8	1.8	1.1	0.4	0.9	0.5	-0.9	-0.4	1.2	-0.3	0.1	0.3	0.6	-1.0
Bipolar Disorder (2011)	0.7	0.7	6.4	1.4	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.3	0.2	0.0	2.5	-1.0	1.4
Crohns Disease (2012)	0.7	1.1	3.0	1.6	0.7	-0.4	-0.0	-0.1	1.4	1.7	0.7	-0.0	1.5	-0.1	1.0	1.4	0.6	-1.6	1.3	0.4
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.8	-0.0	1.1	-0.7	1.7	0.8	0.7	0.4	0.9	0.6	0.4	1.0	1.0	1.2	0.6	1.6	1.0	0.7
Ever had hysterectomy (womb removed)	0.7	0.8	5.9	2.4	0.8	0.3	1.2	0.1	0.5	0.5	0.3	-0.3	1.5	0.9	0.0	0.2	0.7	-0.8	-0.4	0.9
Systolic blood pressure, automated reading	0.7	1.9	8.5	1.3	1.6	0.8	1.9	0.9	1.6	1.4	1.0	-0.2	0.1	1.4	2.1	0.5	1.2	2.9	0.1	1.2
Medication: Co-codamol	0.7	0.8	3.4	1.1	-0.1	1.1	1.8	0.4	-0.8	-0.4	-0.8	-0.9	0.1	1.5	0.3	-0.3	-0.3	-0.6	-0.6	1.3
High blood pressure	0.7	1.9	11.0	-1.0	0.8	-0.2	2.3	2.6	0.4	1.0	0.2	-0.8	0.2	1.2	2.0	-0.3	0.0	3.3	-0.5	0.2
Chronic bronchitis/emphysema (father)	0.7	0.9	4.7	0.4	-0.8	-0.8	-0.7	0.3	-0.7	0.7	-1.2	-2.2	0.4	0.1	1.7	-0.6	-0.9	1.1	-0.4	0.1
Nervous feelings	0.7	1.4	5.0	0.4	0.6	1.5	0.6	1.1	1.5	0.6	0.9	0.6	0.7	0.8	2.0	1.0	1.3	-2.2	1.6	-0.0
Forced vital capacity (FVC)	0.7	2.5	14.0	0.5	2.1	0.7	-3.7	-2.2	1.7	2.1	1.8	0.6	-0.0	-1.7	0.0	-0.1	1.0	-1.6	0.6	0.6
Arm fat percentage (right)	0.7	2.8	10.8	1.2	1.7	0.5	2.5	2.5	1.7	1.8	1.2	-0.1	1.4	1.3	3.3	1.0	0.8	2.2	1.0	-0.0
Pulse rate	0.7	1.1	6.2	0.2	0.5	-2.2	0.0	1.7	-0.2	0.0	0.2	0.0	-1.4	-0.9	0.3	-0.2	-0.8	2.5	-0.9	-0.7
Qualifications: O levels/GCSEs or equivalent	0.7	1.0	5.4	-2.3	-1.0	-1.1	0.2	1.2	-0.1	-0.8	-0.6	0.0	-0.5	-1.3	-0.8	-0.5	-0.4	1.5	-1.0	-1.1
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	3.9	-0.4	-1.7	0.3	-0.2	-0.5	-1.6	-1.8	-1.4	-0.6	-0.6	-1.2	-2.0	-1.3	-1.4	-0.2	-1.1	-0.4
Number of children fathered	0.7	0.8	2.7	0.3	0.7	0.3	-0.6	-0.0	0.9	0.4	1.0	1.6	0.2	-1.2	0.7	1.0	0.8	-0.9	1.6	-1.3
Neck or shoulder pain in last month	0.7	0.9	5.3	0.9	2.3	0.3	-0.6	-0.2	0.9	1.6	1.3	0.2	0.7	0.4	0.8	0.2	1.3	0.4	0.6	0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	4.9	-0.8	-0.4	-1.3	-1.4	2.2	-0.0	-0.7	-0.3	0.4	-0.4	-0.5	-0.3	-0.9	0.3	-0.2	-0.2	-1.4
Hypertension (Self-reported)	0.7	1.8	8.4	-0.7	1.0	-0.1	2.6	2.4	0.6	0.9	0.4	-0.5	-0.0	1.3	2.3	-0.0	0.1	2.9	-0.3	0.2
Arm fat percentage (left)	0.7	2.6	10.7	1.2	1.6	0.6	2.4	2.1	1.8	1.9	1.2	-0.1	1.3	1.2	3.3	1.1	0.9	2.2	1.0	-0.1
Eye problems/disorders: Cataract	0.7	0.8	3.2	-1.3	-0.4	-1.2	-1.2	-1.8	-0.9	0.4	-0.4	-0.3	-1.3	-0.6	0.1	-0.8	-0.2	0.8	-0.9	-0.7
Medication: Blood pressure	0.7	1.3	6.1	0.4	0.7	-0.5	1.9	2.3	0.4	0.1	0.5	0.3	-1.1	0.7	1.6	-0.7	-0.2	2.5	-0.8	-0.7
Triglycerides	0.6	1.0	4.9	-0.5	0.3	-1.7	-1.2	0.1	0.4	-0.5	0.3	0.8	-1.6	-2.2	0.6	-0.1	0.2	-0.0	0.4	-1.8
Lung FEV1/FVC ratio	0.6	3.0	10.2	1.0	2.8	-1.5	-0.1	3.2	2.7	2.2	1.9	0.9	0.7	2.0	1.3	1.5	1.6	-0.1	0.9	0.9
Medication for hormone replacement therapy	0.6	0.6	2.8	-1.7	0.8	-0.3	0.1	-0.1	0.4	0.8	0.1	-0.6	-0.8	-0.1	0.3	-0.3	-0.6	1.4	-1.4	0.9
Medication: Metformin	0.6	0.9	5.3	0.5	-0.5	0.8	0.7	1.3	-1.3	0.1	-0.6	-0.3	1.1	-0.3	-1.0	-0.8	-0.1	2.3	-0.5	-0.8
Severe depression (siblings)	0.6	0.7	2.5	-0.1	0.3	0.7	-0.1	0.9	1.6	0.7	0.9	0.7	-0.7	0.6	1.5	1.0	0.5	-1.0	0.8	0.6
Relative age voice broke	0.6	0.9	2.7	-0.4	-1.1	1.0	-1.0	0.6	-0.3	-0.6	-0.8	-1.0	-0.7	1.6	-1.6	-0.1	-1.5	-1.0	-0.8	0.7
Multivitamins +/- minerals	0.6	0.8	3.5	1.9	1.3	-0.5	-1.3	-0.1	0.8	1.0	0.7	-0.3	0.3	0.1	1.2	-0.2	0.9	0.9	0.8	0.8
Hair/balding pattern: Pattern 2	0.6	0.8	2.6	0.6	-0.3	0.1	-1.6	-1.1	0.0	-1.2	-0.5	-0.5	0.8	-1.1	-0.4	-1.0	-1.0	-1.6	-0.2	0.4
Pain all over the body in last month	0.6	0.7	4.0	-2.0	-0.9	-0.5	0.3	-0.5	-0.3	-0.6	-0.6	-0.2	-1.1	0.7	0.1	0.2	-1.4	-1.2	-0.7	0.0
Father’s age at death	0.6	0.8	3.7	-1.9	-0.6	0.5	0.4	-1.2	-1.2	-0.1	-0.9	-0.9	0.7	-0.8	-0.4	0.2	-1.5	-0.4	-0.7	1.0
Number of live births	0.6	0.8	6.1	2.5	-0.2	0.2	-0.5	-0.3	0.4	0.1	0.2	0.6	1.0	-0.4	0.1	1.0	1.0	-0.8	1.6	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	3.5	0.8	-0.8	1.7	-1.9	0.4	0.3	0.2	0.4	0.1	-0.3	-0.0	0.4	1.1	0.8	-0.4	0.9	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	12.3	0.6	1.8	-0.0	-3.5	-1.4	1.6	1.5	1.7	0.9	0.5	-1.6	-0.9	0.4	1.1	-1.2	0.7	0.6
Breastfed as a baby	0.6	0.7	2.5	-0.0	0.5	-0.7	-1.0	-1.5	-0.7	0.3	-0.9	-1.4	0.6	0.1	-0.2	-0.4	-0.9	0.8	-1.6	0.2
Birth weight of first child	0.6	1.1	3.5	-0.8	-0.9	-0.5	0.1	-0.8	-0.3	-0.9	-0.6	-0.7	-1.3	-1.0	-1.7	-1.5	-1.6	0.3	-1.9	-0.9
Peak expiratory flow (PEF)	0.6	1.4	6.7	0.4	1.0	-1.0	-2.6	-1.8	1.0	1.1	1.1	0.7	-1.3	-1.3	-0.5	0.0	0.1	-2.0	0.0	-0.8
Birth weight	0.6	1.2	3.6	1.2	-0.7	0.0	-0.7	-0.6	-0.9	-1.2	-0.8	-0.6	-1.9	-1.2	-1.9	-1.8	-1.2	-0.4	-1.2	-0.1
Forced vital capacity (FVC), Best measure	0.6	2.1	9.3	0.7	1.9	0.6	-3.0	-2.4	1.4	1.8	1.7	0.8	0.3	-1.9	-0.7	0.1	1.1	-0.9	0.8	0.7
Body fat percentage	0.6	2.3	8.2	1.5	1.5	1.0	2.7	1.6	1.6	1.7	1.3	0.3	1.3	1.0	2.9	1.2	0.9	1.6	1.2	-0.1
Leg fat percentage (right)	0.6	2.3	10.4	1.8	1.5	0.9	3.2	1.4	1.4	1.7	1.2	0.3	1.5	1.1	2.3	1.3	1.0	1.1	1.3	0.3
Wheeze or whistling in the chest in last year	0.6	1.0	4.1	-2.0	-0.4	0.4	1.1	-0.4	-1.3	0.1	-1.0	-1.7	0.1	0.5	-0.4	-1.3	-1.3	1.2	-0.9	0.6
Eye problems/disorders: None of the above	0.6	0.7	2.8	0.5	-0.0	0.9	-0.3	1.7	1.0	0.6	0.2	-0.1	1.6	0.5	0.9	1.2	0.2	-0.8	0.8	0.8
Illnesses of father: None of the above (group 1)	0.6	0.7	2.7	-0.9	-0.2	-1.0	-1.0	-0.9	-0.3	-0.9	0.0	0.7	-1.1	-1.6	-0.8	-0.1	-0.5	-0.7	-0.5	-1.2
Average weekly champagne plus white wine intake	0.6	0.8	1.7	-0.6	0.3	1.2	-0.8	-0.5	0.9	-0.3	1.0	1.3	-0.3	-1.1	-0.9	0.8	1.1	-1.2	1.3	-0.7
Eye problems/disorders: Glaucoma	0.6	0.7	2.4	-0.9	-0.5	-0.2	0.6	-0.2	-0.8	-1.1	-0.4	-0.2	-1.5	-0.0	-0.6	-1.4	-1.0	1.2	-1.1	-0.7
Leg fat percentage (left)	0.6	2.0	10.5	1.6	1.5	0.6	3.2	1.4	1.3	1.6	1.3	0.3	1.1	0.9	2.2	1.0	0.7	1.2	1.0	-0.0
Cholesterol lowering medication	0.6	0.9	4.1	1.4	0.7	0.6	2.0	1.1	-0.2	-0.2	0.5	1.0	-0.3	0.3	0.2	0.0	0.9	2.0	0.0	-0.3
Bipolar Disorder (2018)	0.5	0.7	2.1	-0.1	0.0	0.6	-0.4	1.3	0.1	-1.0	-0.4	-1.4	-0.0	0.7	0.8	-0.4	-1.4	1.3	-0.9	0.8
Depression (Nagel 2018)	0.5	0.8	2.6	-0.5	-0.6	1.6	0.6	-0.7	-1.0	-1.2	-0.5	0.1	-1.5	-0.7	0.0	-1.1	-0.8	-1.4	-0.0	-1.0
Schizophrenia (2018)	0.5	0.9	3.2	1.0	1.5	0.9	-0.1	0.5	0.7	0.8	1.2	1.2	0.7	-0.8	0.2	0.9	1.8	0.6	1.4	-0.3
Verbal and Numeric Reasoning (VNR)	0.5	1.3	4.4	-0.6	0.4	-1.0	-0.1	1.9	0.5	2.1	0.3	-0.8	2.1	1.1	-0.4	0.4	0.2	0.7	0.1	2.1
LDL Cholesterol	0.5	0.8	2.6	-1.6	0.4	-1.4	-0.3	0.1	-0.2	-0.6	-0.4	-0.3	-1.4	-1.0	1.1	-0.4	-0.3	1.2	-0.5	-1.3
Type 2 Diabetes (T2D) (2012)	0.5	0.6	3.0	1.7	0.0	-0.0	-0.6	0.6	0.4	-0.4	0.2	-0.3	0.2	1.6	1.2	0.5	0.4	0.0	1.1	0.6
Average weekly spirits intake	0.5	0.6	4.0	-0.3	-0.4	0.2	1.4	0.0	-0.1	0.7	-0.4	-0.8	-2.0	0.7	0.5	-0.7	-1.1	0.6	-0.3	0.2
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	4.0	-0.2	0.5	0.7	1.6	1.2	-0.4	-0.1	0.0	0.5	-0.4	0.8	-0.3	0.4	-0.4	2.0	-0.7	0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	4.7	-0.8	-0.5	2.2	0.0	0.1	-0.7	-0.5	-0.6	-0.5	-1.0	0.7	0.4	-0.3	-0.7	-1.2	-0.0	-0.3
Age when periods started (menarche)	0.5	1.2	5.9	-1.3	-0.9	-0.9	-1.4	-1.5	-0.4	0.1	0.2	0.6	-2.0	-2.4	-0.9	-0.9	-0.0	-0.3	-0.1	-1.1
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.7	-0.3	-0.4	-0.9	0.1	-0.5	-0.5	-1.2	-0.9	-0.7	-0.6	-0.3	0.4	-1.2	-0.8	-1.3	-0.3	-0.3
Number of incorrect matches in round	0.5	0.8	4.6	0.3	0.6	1.2	-2.1	0.5	0.1	0.9	0.3	0.1	1.1	0.4	0.5	1.2	0.6	-0.3	1.2	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	2.8	1.0	0.3	1.3	1.7	-0.7	-0.0	0.6	-0.2	-0.8	-0.2	1.2	1.2	-0.2	-0.2	-1.4	0.2	1.4
Medication: Simvastatin	0.5	0.8	5.7	0.8	-0.1	2.4	1.4	0.5	-0.6	-0.0	0.3	0.5	1.2	-0.6	-0.2	-0.0	0.5	1.2	0.2	-0.3
Alcohol intake versus 10 years previously	0.5	0.8	5.0	2.2	-0.4	0.3	-1.2	0.1	-0.5	-0.9	-0.5	-0.7	0.2	-0.4	-0.1	-0.9	-0.6	1.0	-1.2	1.0
Qualifications: A levels/AS levels or equivalent	0.5	1.1	5.1	-2.2	-0.9	-0.9	-0.8	0.6	-0.2	-1.3	-0.7	0.2	-0.3	-2.3	0.3	-1.1	0.1	0.8	-0.2	-1.3
Standing height	0.5	5.2	56.1	-0.1	0.4	-0.5	-1.9	-7.5	0.5	-0.4	0.9	0.7	-1.8	-4.1	-1.0	-0.0	-0.1	-2.3	0.3	-1.1
Length of working week for main job	0.5	0.6	2.1	-0.9	0.6	1.0	0.7	-0.3	0.4	0.2	0.9	1.3	-0.3	-1.2	0.5	0.2	0.1	0.6	0.7	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	5.0	-0.4	-0.1	-0.3	-2.2	1.2	-0.0	0.7	-0.2	-1.7	0.6	0.4	0.1	-0.6	-0.6	-0.2	-0.3	0.7
Headache pain in last month	0.5	0.8	4.0	-1.3	0.0	-0.3	-0.6	-1.4	0.1	-0.3	-0.0	-0.1	-1.6	-2.0	0.2	-1.2	0.2	-0.2	-0.1	-0.9
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	3.0	1.7	-0.1	-1.0	-0.8	-1.6	-0.0	-0.5	-0.1	0.5	-1.6	-0.1	-0.9	-0.8	-0.2	-1.0	-0.4	-0.3
Glaucoma (self-reported)	0.5	0.6	1.9	-1.1	-0.4	-0.5	0.6	-0.3	-0.7	-0.9	-0.1	0.1	-1.1	-0.2	-1.1	-1.4	-0.4	0.6	-0.8	-0.9
High blood pressure (siblings)	0.5	0.8	3.1	1.5	0.6	0.8	-0.1	0.2	1.0	0.1	1.3	1.1	-0.2	0.6	0.6	0.6	1.8	0.7	0.6	0.7
Worry too long after embarrassment	0.5	0.8	3.0	-1.7	-0.4	0.2	0.4	1.5	-0.1	0.2	-0.6	-1.1	-1.0	-0.7	1.5	-1.0	-0.9	-0.5	-0.2	-0.6
Medication for pain relief, constipation, heartburn	0.5	0.9	1.8	1.0	0.5	-0.8	-1.4	0.8	1.2	0.5	1.2	1.3	-0.0	-0.0	0.4	1.2	1.2	0.8	1.2	-0.9
Mean time to correctly identify matches	0.5	1.0	6.6	0.1	0.7	0.2	0.5	1.0	-0.4	0.4	-0.7	-0.9	1.7	1.2	-0.8	-0.6	-0.3	2.6	-0.5	0.9
Chest pain or discomfort	0.5	0.7	2.0	-0.9	0.0	1.4	1.3	-0.7	0.2	0.7	0.1	-0.9	1.1	1.4	-0.4	-0.1	0.0	-0.8	-0.3	1.4
Medication: Aspirin	0.5	0.7	3.0	0.1	-0.1	0.7	1.7	-0.8	-1.3	0.5	-0.9	-1.1	-0.0	-0.5	-0.6	-0.6	-1.1	0.6	-0.7	0.5
Knee pain experienced in last month	0.5	0.7	1.9	1.2	1.0	1.0	1.1	-0.5	-0.0	1.4	0.7	0.3	0.7	0.7	0.8	1.2	1.0	0.3	0.5	0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	3.0	0.6	-0.1	1.7	0.9	0.2	-0.0	0.4	0.3	-0.3	0.3	0.8	-0.3	0.6	-1.2	-1.3	-0.2	0.4
Mood swings	0.5	1.0	6.1	1.5	0.1	2.2	0.9	-0.9	-0.1	-0.4	-0.0	-0.2	-0.6	-0.6	0.3	-0.6	-0.5	-2.5	0.2	-0.8
Loneliness, isolation	0.5	0.7	4.2	-0.4	-0.2	1.0	0.9	1.0	-0.2	0.7	-0.7	-1.4	0.3	0.6	2.1	-0.0	0.5	0.5	0.3	0.7
Qualifications: nursing, teaching	0.5	0.8	3.7	-1.5	0.4	1.9	-1.4	1.5	0.5	-0.1	0.3	0.5	-0.4	-0.4	-0.3	0.5	-0.6	1.0	-0.3	0.4
Number of self-reported non-cancer illnesses	0.5	0.9	4.3	-0.6	0.4	0.6	1.1	0.8	-0.2	0.9	-0.5	-1.7	0.8	0.8	1.2	-0.2	-0.9	2.1	-0.8	0.7
Guilty feelings	0.5	0.7	2.2	-0.6	-0.8	1.0	-1.5	0.2	-1.3	-0.8	-0.9	-0.6	-0.3	-0.5	0.3	-1.4	-0.8	-0.7	-0.0	-1.0
Commuting to job workplace: Public transport	0.5	0.6	2.3	-1.5	-1.0	-0.4	-0.9	-0.3	-1.2	-0.8	-0.8	-0.4	-0.4	-0.7	-0.7	-0.8	-1.0	0.0	-0.9	-0.4
High cholesterol (Self-reported)	0.5	0.9	2.9	1.2	0.7	1.6	1.1	1.7	-0.1	0.6	0.3	-0.1	1.5	0.2	0.1	0.3	0.5	1.7	-0.5	0.8
Alcohol drinker status: Never	0.5	0.7	4.9	0.1	1.3	0.4	-0.3	-0.8	0.7	2.2	0.4	-0.6	0.4	0.6	0.7	0.6	0.5	0.3	0.7	0.7
Age started oral contraceptive pill	0.5	0.6	1.4	-0.7	1.0	-0.8	1.0	0.6	0.7	0.5	1.2	1.1	0.1	-0.3	-0.3	0.7	0.9	1.0	0.4	-0.5
Pain experienced in last month	0.5	0.8	3.1	0.6	0.2	-0.5	-0.6	0.2	1.8	0.4	0.9	1.0	-0.4	0.6	1.4	1.5	0.9	-0.6	1.1	-0.4
Alzheimer’s Disease (in mother)	0.4	0.5	4.1	0.1	-0.5	-0.4	-2.0	0.3	0.7	0.1	0.4	-0.1	0.8	0.2	0.2	0.4	0.3	-0.8	0.7	0.7
Prostate Cancer	0.4	0.5	1.9	-1.0	-0.3	1.1	0.4	-1.4	-1.0	-0.1	-0.5	-0.9	-0.4	-0.5	-0.1	-0.1	-1.2	0.8	-0.4	0.7
Coronary Artery Disease (CAD)	0.4	0.5	1.8	-0.5	0.0	-1.1	1.3	-0.3	0.1	0.9	-0.0	-0.8	0.8	0.2	1.2	-0.5	0.1	1.2	-0.3	0.1
Mean Putamen Volume	0.4	0.4	1.6	-0.5	-0.2	-0.8	-1.2	0.5	0.0	-0.5	-0.5	-1.2	0.2	-0.4	1.0	-0.9	-0.5	-0.4	-0.3	-0.2
Rheumatoid Arthritis	0.4	0.5	2.0	-0.1	0.0	-0.1	0.2	-0.3	0.6	0.4	0.8	0.9	-0.5	-0.2	0.8	1.1	1.1	1.4	0.7	-0.1
Schizophrenia (2014)	0.4	0.8	3.4	0.2	0.0	1.3	-0.3	0.1	0.9	0.3	1.4	1.3	-0.4	-1.8	-0.0	0.4	1.0	1.0	0.6	-1.0
Blood Red Count	0.4	3.4	8.1	2.5	2.1	1.1	2.5	2.2	2.1	2.4	1.7	1.0	1.1	0.9	2.8	1.6	1.3	2.0	1.4	0.5
BMI	0.4	2.0	8.7	2.1	2.2	0.6	2.8	0.1	1.4	1.2	1.1	-0.2	0.4	0.2	3.0	0.4	0.7	1.7	0.4	0.1
Lung FVC	0.4	1.9	7.1	0.3	1.8	1.5	-2.7	1.7	1.3	2.0	1.5	0.8	1.1	0.2	0.2	0.4	1.6	0.9	1.0	1.2
Number of treatments/medications taken	0.4	0.7	4.2	-0.8	1.0	0.0	2.0	0.2	-0.7	-0.2	-0.0	-0.4	-0.2	0.3	0.0	-0.8	-0.6	1.9	-1.1	-0.2
Hearing difficulty/problems: Yes	0.4	0.5	3.7	-1.0	0.3	-1.9	-0.6	-0.2	-0.1	0.2	0.4	0.7	0.9	-0.3	-0.1	1.1	0.5	0.2	1.0	-0.1
Trunk fat percentage	0.4	1.8	6.2	1.6	1.3	0.9	2.4	1.0	1.4	1.4	1.1	0.2	1.0	0.8	2.5	1.0	0.6	1.6	0.9	-0.2
Maternal smoking around birth	0.4	0.6	4.0	-0.8	-0.4	1.0	-0.1	0.1	-0.7	-0.9	-0.5	0.2	-2.0	-0.3	-0.7	-0.5	-0.9	0.5	-0.5	-0.6
Sitting height	0.4	2.7	29.0	0.6	0.4	-0.1	-1.0	-5.4	0.2	0.2	0.8	0.5	-1.1	-3.4	-0.8	0.0	0.3	-1.1	0.3	-0.5
High blood pressure (mother)	0.4	0.6	5.1	-0.8	-0.5	-0.2	1.3	2.3	-0.6	-0.3	-0.5	-0.7	0.6	-0.1	-0.1	-0.7	-0.0	0.2	-0.5	-0.3
Body mass index (BMI)	0.4	1.7	9.3	0.8	1.6	0.3	3.1	1.1	1.1	1.2	0.6	-0.5	0.9	1.2	2.6	0.4	0.4	1.5	0.4	0.3
Trunk fat mass	0.4	1.5	6.0	1.4	1.5	0.7	2.4	-0.5	1.5	1.4	1.3	0.3	0.5	-0.1	2.4	0.8	0.5	1.1	0.9	-0.5
Ever unenthusiastic/disinterested for a whole week	0.4	0.4	2.3	0.1	-0.7	0.4	-0.5	0.2	-1.0	0.2	-1.3	-1.5	0.3	0.2	0.6	-0.6	-0.6	-0.1	-0.4	0.1
Fluid intelligence score	0.4	0.8	3.2	-0.9	0.2	-0.8	-0.4	1.1	0.7	1.8	0.8	0.4	1.7	-0.4	-0.2	0.3	1.3	0.7	0.8	0.7
Neuroticism score	0.4	0.7	6.5	-0.4	-0.3	2.5	0.3	1.0	-0.1	-0.2	0.1	0.2	-0.9	0.4	1.3	0.0	-0.4	-1.1	0.5	-0.6
Trunk fat-free mass	0.4	2.0	23.2	-0.6	1.2	-0.4	0.4	-4.8	0.9	0.5	0.7	-0.1	-1.2	-2.2	0.6	0.1	0.0	-0.7	0.3	-0.1
Depression (self-reported)	0.4	0.5	3.0	0.3	-0.3	-1.7	0.9	0.6	-0.2	0.2	-0.3	-0.4	-0.3	-0.2	0.9	-0.3	-0.1	1.4	-0.1	-0.2
Illnesses of mother	0.4	0.5	3.8	1.9	-0.2	-0.6	-0.3	-0.0	0.5	0.8	0.2	0.0	-0.0	0.0	-0.1	1.4	0.6	0.8	-0.1	0.6
Pulse wave Arterial Stiffness index	0.4	0.4	2.0	-0.3	0.1	-0.4	1.1	-0.6	-0.7	-0.4	-0.7	-0.9	-0.2	-0.1	-0.4	-0.7	-0.6	0.5	-1.4	-0.3
Arm fat mass (right)	0.4	1.5	6.7	0.9	1.6	0.3	2.6	0.3	1.2	1.3	0.8	-0.4	0.7	0.6	2.6	0.4	0.3	1.8	0.4	-0.0
Trunk predicted mass	0.4	2.1	24.3	-0.7	1.1	-0.5	0.4	-4.9	0.9	0.5	0.7	-0.1	-1.2	-2.3	0.6	0.1	-0.0	-0.7	0.2	-0.1
Exposure to tobacco smoke at home	0.4	0.4	1.6	1.0	0.1	-0.6	1.3	-0.1	-0.1	1.0	0.1	-0.5	0.9	0.9	0.9	0.3	0.3	-0.1	0.3	0.7
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.4	0.7	-0.7	0.4	0.5	-0.0	-1.6	-0.7	-0.6	-0.2	0.1	-1.0	-1.1	-0.4	-0.8	0.3	0.1	-0.6
Loud music exposure frequency	0.4	0.4	2.2	-0.3	-0.5	1.5	0.1	0.5	-1.2	-0.4	-0.2	0.2	-0.0	0.9	-1.1	0.6	-0.4	0.1	-0.1	-0.6
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.8	-0.8	0.8	0.6	-0.8	1.0	0.0	0.7	-0.1	-0.4	-1.0	-0.3	0.0	-1.0	-1.1	0.7	-1.3	-0.1
Arm fat-free mass (right)	0.4	1.9	22.6	-1.0	0.9	-0.5	1.4	-4.8	0.6	0.3	0.3	-0.5	-1.2	-1.6	0.6	-0.3	-0.4	-0.5	-0.3	0.1
Emphysema/chronic bronchitis	0.4	0.4	1.4	-0.2	-0.5	0.4	1.2	0.0	-1.2	-0.8	-0.4	-0.4	0.2	1.0	-0.7	-0.5	-0.2	-0.4	-0.7	0.6
Medication: Blood pressure	0.4	0.7	2.4	-1.3	0.4	-0.1	1.6	1.4	0.2	0.0	-0.4	-1.2	1.1	0.7	1.5	0.1	0.3	0.8	-0.1	0.1
Medication: Omeprazole	0.4	0.5	1.4	-0.7	-0.0	-0.6	0.9	-1.0	-0.2	-0.9	0.3	0.6	-0.9	-1.0	0.7	-0.4	-0.1	-1.2	-0.0	-0.8
Heart disease (mother)	0.4	0.5	4.9	-1.2	0.6	2.2	0.4	0.8	0.2	0.1	0.5	0.5	-0.3	0.2	0.3	-0.5	-0.0	0.1	0.5	0.4
Comparative height size at age 10	0.4	2.0	15.2	0.6	0.9	-0.9	0.2	-3.9	0.9	0.3	1.4	1.5	-0.3	-2.2	0.0	1.1	0.9	-0.4	1.3	-1.7
Average weekly red wine intake	0.4	0.6	3.4	0.7	0.3	-0.6	0.1	1.9	0.7	1.7	0.4	-0.3	0.9	1.2	0.5	-0.1	-0.2	0.6	-0.3	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	3.6	0.4	0.2	-1.2	-1.9	0.3	0.0	0.1	0.3	0.2	0.1	0.3	-0.9	-0.1	-0.3	-0.3	-0.6	-0.3
Medication: Gliclazide	0.4	0.5	1.9	1.0	0.1	0.2	0.0	0.2	-1.3	-0.4	-0.5	0.4	0.0	-0.2	-1.4	-0.7	-0.7	1.2	-0.7	-0.4
Arm fat mass (left)	0.4	1.6	7.4	0.8	1.6	0.5	2.6	0.1	1.4	1.5	0.9	-0.3	0.8	0.6	2.7	0.8	0.5	1.6	0.7	0.1
Miserableness	0.4	0.6	3.9	-0.0	0.2	2.0	0.9	-0.2	-0.1	0.7	0.4	-0.2	-0.9	-0.6	0.9	-0.2	-0.5	-1.2	0.2	-1.2
Medication: Lisinopril	0.4	0.5	3.7	0.6	0.5	-0.4	0.4	1.8	0.3	-0.2	-0.0	-0.2	0.3	0.4	1.9	0.0	-0.2	0.1	-0.4	-0.6
Illnesses of father: High blood pressure	0.4	0.5	2.4	-1.4	-0.2	1.6	-0.0	-0.3	-0.0	0.3	-0.3	-0.6	0.1	-0.1	0.9	-1.2	-0.0	-0.7	-0.2	0.5
Heart attack/myocardial infarction (self-reported)	0.4	0.5	4.8	-2.2	-0.5	0.1	-0.1	-0.8	-0.6	0.2	-0.9	-0.5	-0.3	0.4	0.7	-0.4	-0.8	-0.2	-0.2	0.1
Depressed Affect (Nagel 2018)	0.3	0.6	2.3	1.5	0.1	1.2	1.2	0.3	0.4	0.9	0.3	0.1	0.2	0.4	1.5	0.6	0.3	0.0	1.2	0.0
Worry (Nagel 2018)	0.3	0.5	1.8	0.5	-0.5	1.4	0.9	0.3	0.0	-0.6	-0.0	0.4	-0.3	0.9	0.7	0.6	0.1	-1.3	1.3	0.5
Irritable Bowel Disease (IBD)	0.3	0.8	3.1	-0.4	-0.4	-0.2	0.7	-0.2	-0.3	-0.8	-1.1	-1.1	-1.1	-0.7	-0.4	-1.8	-0.8	-0.3	-1.0	-1.7
Major Depression (MDD)	0.3	0.4	1.8	-1.3	0.4	0.5	-0.1	-0.4	0.0	0.3	0.4	0.3	-0.8	-1.4	0.2	-0.5	-0.2	-0.6	0.3	-0.4
Reaction Time	0.3	0.7	2.3	-0.6	-0.0	-0.4	0.2	0.8	-0.8	-0.1	-0.9	-1.0	0.7	0.5	-1.4	-1.5	-0.9	1.0	-0.9	-0.2
HDL Cholesterol	0.3	0.6	2.0	1.4	-0.1	1.1	1.3	0.8	0.3	-0.1	0.4	0.5	0.2	1.2	-0.4	-0.4	-0.4	-1.2	0.5	0.4
Primary Biliary Cirrhosis	0.3	0.5	2.1	0.1	0.2	-0.8	-0.1	-1.4	-0.2	-0.0	-0.2	-0.0	-0.4	-1.5	-0.2	-0.6	-0.5	-1.2	-0.0	-0.7
Height	0.3	6.2	76.9	1.6	1.2	0.3	-2.1	-8.8	0.6	0.7	1.0	0.2	-0.2	-3.3	-2.3	-0.1	0.4	-1.3	0.2	0.8
Smoking Status	0.3	0.6	3.2	-1.7	0.2	-0.6	-0.0	0.8	-0.3	-0.2	-0.1	-0.4	-1.0	-0.8	0.1	-0.4	-0.1	0.5	-0.9	-1.8
Neuroticism	0.3	0.6	2.8	0.5	-0.4	1.5	1.0	1.7	-0.6	-0.5	-0.1	0.0	-0.9	0.4	0.8	-0.5	-0.7	-0.1	0.6	-0.8
Chronotype (morning person)	0.3	0.7	4.2	1.2	0.8	0.0	-2.0	-1.3	0.8	-0.3	0.8	0.6	0.2	0.1	0.5	-0.1	0.6	-0.9	0.2	-0.4
Sensitivity / hurt feelings	0.3	0.5	2.2	-0.7	-0.3	0.9	0.9	1.5	-0.4	0.5	0.1	-0.1	-0.7	-0.1	0.7	-0.3	-1.0	0.2	-0.5	-1.5
Diabetes (mother)	0.3	0.4	1.2	-0.6	0.5	1.1	0.2	0.6	0.2	-0.1	-0.1	-0.1	-0.7	-0.8	0.8	-0.6	-0.4	0.3	-0.8	-0.7
Fed-up feelings	0.3	0.5	1.8	-0.8	-0.5	1.3	1.0	-0.1	-0.8	-0.3	0.1	0.3	-1.0	-0.5	-0.0	-0.4	-0.4	-0.6	-0.1	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	2.8	-0.8	0.4	0.5	-0.2	-1.7	-0.2	0.8	0.5	0.2	-1.3	-1.5	0.1	-0.2	-1.0	-0.6	-0.8	-1.1
Medication: Atenolol	0.3	0.3	2.9	0.4	-0.3	0.7	-0.7	1.7	0.3	-0.6	0.1	0.5	0.3	0.5	-0.0	-0.2	0.1	0.4	-0.2	-0.2
Medication: Levothyroxine sodium	0.3	0.6	2.4	-0.4	-0.7	0.5	0.5	-0.5	-0.9	-1.1	-0.6	0.1	-0.3	-1.4	-1.5	-1.0	-0.4	0.3	-0.4	-0.0
Waist circumference	0.3	1.2	9.9	0.5	1.0	-0.2	3.1	-0.1	0.6	1.0	0.1	-1.0	0.5	0.5	2.1	0.0	-0.3	1.5	-0.3	-0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	3.0	-0.6	0.3	0.1	0.3	-1.1	-0.2	0.6	0.3	-0.2	-1.2	-1.7	-0.0	-0.6	-1.4	-0.6	-0.8	-1.2
Mouth/teeth dental problems	0.3	0.5	3.3	1.1	-0.6	-1.8	-0.7	-0.5	0.0	-0.2	0.5	0.6	0.2	-0.6	-0.1	0.8	0.5	-0.2	0.1	-0.7
Heart attack	0.3	0.4	3.2	-1.8	-0.2	0.4	-0.1	-0.6	-0.2	0.5	-0.6	-0.3	-0.0	0.5	1.0	0.1	-0.3	-0.1	0.2	0.4
Medication: Ramipril	0.3	0.4	2.3	-0.4	-0.0	-0.7	-0.9	0.1	-0.3	-1.1	-0.2	-0.4	-0.1	0.2	-1.5	-0.9	-0.1	0.6	-0.5	-0.1
Weight	0.3	1.3	4.6	0.6	1.7	0.1	2.0	-2.1	1.4	1.1	1.1	-0.0	0.1	-0.7	2.1	0.4	0.3	0.4	0.6	-0.2
Hair/balding pattern: Pattern 3	0.3	0.4	2.0	-0.1	0.2	0.8	-0.2	-0.5	-0.5	0.1	-0.5	-0.6	0.4	1.4	-0.9	0.4	-0.5	-1.0	-0.1	0.8
Pulse wave reflection index	0.3	0.4	2.5	-0.8	0.0	0.3	1.1	-1.6	0.3	0.3	0.1	0.1	0.7	0.6	-0.1	1.0	0.8	-0.3	0.3	0.3
Blood clot in the leg (DVT)	0.3	0.4	2.4	-0.9	-0.0	0.1	-0.0	-1.5	-0.6	-0.5	-0.5	-0.0	-0.2	1.0	-0.2	0.3	-0.6	0.6	0.1	0.6
Medication: Ventolin 100micrograms inhaler	0.3	0.3	1.2	0.3	0.0	-0.6	1.1	0.1	-0.5	-0.3	0.1	-0.2	-0.1	-0.9	-0.9	-0.7	-0.5	0.4	-0.3	-0.9
Comparative body size at age 10	0.3	0.9	8.0	0.5	1.1	-0.2	-0.2	2.8	0.7	0.9	0.1	-0.9	0.5	0.6	1.7	-0.3	0.3	0.5	0.2	0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	2.1	-0.3	-0.2	0.1	-0.6	0.4	-0.8	0.1	-0.8	-1.4	0.9	0.3	-0.1	-0.5	-0.2	-0.4	-0.3	0.8
Pulse wave peak to peak time	0.3	0.4	1.7	0.5	-0.2	0.3	-1.2	0.1	0.6	0.2	0.7	0.9	0.1	-0.2	0.3	0.5	0.5	-0.8	1.3	0.1
Medication: Allopurinol	0.3	0.4	2.7	-0.0	0.6	-0.4	0.6	-0.4	0.1	0.6	0.1	-0.1	-0.1	-1.3	1.6	-0.3	0.1	0.5	0.1	-0.3
Whole body fat mass	0.3	1.4	6.8	1.1	1.4	0.6	2.5	-0.4	1.4	1.2	1.0	-0.0	0.7	0.3	2.6	0.7	0.5	1.0	0.8	-0.2
Leg fat mass (right)	0.3	1.3	10.5	0.9	1.3	0.5	3.2	-0.4	1.0	0.9	0.8	-0.0	0.5	0.3	2.1	0.4	0.4	0.9	0.7	-0.2
Arm predicted mass (right)	0.3	1.7	21.1	-0.5	0.9	-0.3	1.4	-4.6	0.5	0.2	0.2	-0.6	-1.0	-1.4	0.7	-0.3	-0.3	-0.4	-0.2	0.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	2.2	-0.0	0.8	-0.7	1.5	-1.1	0.3	-0.1	-0.1	-0.1	-0.3	-0.1	-0.4	-0.1	-1.0	0.1	-0.4	-0.0
Illnesses of siblings: Diabetes	0.3	0.3	1.1	-0.2	-0.2	-0.3	0.6	-0.2	-0.9	-1.1	-0.7	-0.3	-0.7	0.1	0.1	-0.9	-0.8	0.3	-0.5	-0.3
Whole body fat-free mass	0.3	1.7	20.2	-0.5	1.1	-0.4	0.8	-4.5	0.8	0.2	0.4	-0.4	-1.1	-1.8	0.8	-0.3	-0.3	-0.3	-0.0	-0.2
Breast cancer (self-reported)	0.3	0.3	1.5	-0.0	-0.5	-0.0	0.4	-0.7	-0.0	-0.9	-0.3	0.7	-0.5	0.3	-1.2	-0.5	0.7	-0.9	0.0	-0.1
Whole body water mass	0.3	1.6	19.6	-0.6	1.0	-0.5	0.9	-4.4	0.8	0.1	0.3	-0.5	-1.0	-1.7	0.9	-0.3	-0.3	-0.3	-0.1	-0.1
Medication: Bendroflumethiazide	0.3	0.4	1.4	-1.1	0.5	-0.7	0.0	1.2	0.9	0.2	0.5	-0.0	-0.1	0.9	0.9	0.4	0.4	0.3	0.4	-0.2
Basal metabolic rate	0.3	1.5	15.9	-0.2	1.2	-0.3	1.1	-4.0	1.0	0.4	0.6	-0.4	-0.8	-1.5	1.3	-0.1	-0.1	-0.2	0.1	-0.2
Arm fat-free mass (left)	0.3	1.6	16.9	-0.7	1.2	-0.3	1.8	-4.1	0.6	0.2	0.3	-0.6	-1.0	-1.2	0.7	-0.3	-0.4	-0.4	-0.3	0.3
Ever depressed for a whole week	0.3	0.4	1.9	-1.1	0.3	-0.1	-0.7	0.4	-0.2	0.8	-0.5	-0.9	0.9	0.1	1.4	-0.2	0.2	0.4	0.1	-0.5
Supplements: Calcium	0.3	0.3	2.6	0.3	1.6	-0.7	0.3	0.3	0.4	0.3	0.6	0.6	-0.2	-0.1	-0.5	0.3	0.3	-0.5	0.2	0.5
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	2.3	-0.7	0.1	-0.0	-0.2	-1.5	-0.7	-0.5	-0.5	-0.1	-0.1	1.1	-0.3	0.3	-0.6	0.8	-0.1	0.7
Alcohol drinker status: Previous	0.3	0.4	1.7	-0.4	0.4	0.3	-0.0	0.1	-0.4	-1.3	-0.4	-0.4	0.1	0.4	-0.7	-0.9	-0.1	1.1	-0.8	0.8
Leg fat mass (left)	0.3	1.3	11.0	0.7	1.3	0.3	3.3	-0.5	0.9	0.8	0.8	-0.1	0.4	0.2	2.0	0.3	0.2	0.9	0.5	-0.4
Arm predicted mass (left)	0.3	1.6	18.3	-0.6	1.1	-0.3	1.7	-4.3	0.5	0.2	0.2	-0.7	-0.9	-1.2	0.7	-0.3	-0.4	-0.4	-0.4	0.4
Bipolar Disorder or Schizophrenia	0.2	0.5	1.7	0.7	1.3	0.9	-0.5	1.2	0.7	0.0	0.7	0.0	0.4	-0.2	0.6	0.4	0.5	1.1	0.5	0.2
Neuroticism (Nagel 2018)	0.2	0.6	2.1	0.6	-0.1	1.5	1.4	0.6	0.2	0.3	0.4	0.2	-0.2	0.7	1.3	0.1	-0.2	-1.0	1.2	-0.2
Crohns Disease (2017)	0.2	0.4	1.7	0.1	0.3	1.0	-0.4	-0.7	0.8	-0.9	0.2	0.3	-0.0	-0.5	0.1	-0.1	0.2	-1.3	0.8	-1.3
Body Mass Index (BMI) (2010)	0.2	0.2	0.9	0.9	-0.7	0.3	-0.4	0.5	-0.3	0.2	-0.2	0.2	0.3	0.5	-0.1	0.8	0.3	0.9	-0.0	0.2
Blood White Count	0.2	1.2	6.8	0.6	-0.1	-1.8	0.3	-1.7	-0.3	-0.9	0.7	1.5	-0.3	-2.6	0.2	-0.6	0.9	-0.3	0.6	-1.5
Systolic Blood Pressure	0.2	1.0	3.2	1.8	0.8	-0.1	0.3	0.7	1.5	1.3	0.7	-0.3	0.6	0.8	1.7	0.4	1.3	1.1	0.6	1.0
Hair Pigment	0.2	5.4	11.3	1.2	2.6	2.0	-2.4	-0.0	3.1	2.4	2.3	1.5	2.3	1.5	3.0	3.2	3.4	-1.5	3.2	1.3
Relative age of first facial hair	0.2	0.5	2.0	0.6	-0.8	-0.7	-1.4	-0.7	0.4	0.1	0.0	-0.1	-1.1	-0.4	0.4	0.1	-0.5	-1.3	0.2	-0.4
Diabetes (father)	0.2	0.3	1.1	-0.2	-0.2	0.2	0.5	0.5	-0.2	0.2	-0.9	-1.1	-0.2	0.6	0.1	-0.4	-0.7	1.0	-0.5	0.3
Impedance of leg (right)	0.2	0.8	3.6	0.7	-1.3	0.8	-1.1	-0.3	-0.7	-0.0	0.2	1.1	0.1	-0.8	-1.4	0.5	0.6	-1.9	0.8	-0.5
Leg fat-free mass (left)	0.2	1.1	11.6	-0.2	0.9	-0.3	1.1	-3.4	0.7	-0.1	0.1	-0.8	-0.6	-1.0	1.3	-0.6	-0.5	0.1	-0.3	-0.2
Current tobacco smoking	0.2	0.4	1.6	-0.5	0.4	-0.3	-0.7	-0.4	0.1	0.8	0.8	0.6	-1.0	-1.1	0.2	0.0	0.6	-0.1	-0.0	-1.3
Impedance of leg (left)	0.2	0.9	3.8	0.2	-1.0	0.4	-1.2	-0.4	-0.6	0.1	0.5	1.3	-0.3	-1.2	-1.3	0.4	0.6	-1.9	0.7	-1.0
Leg predicted mass (left)	0.2	1.1	12.2	-0.3	0.9	-0.4	1.1	-3.5	0.7	-0.0	-0.0	-0.9	-0.6	-1.0	1.3	-0.6	-0.6	0.0	-0.4	-0.1
Had other major operations	0.2	0.3	1.3	1.1	0.2	-0.9	-0.6	0.1	0.8	0.5	0.3	0.2	-0.3	0.7	-0.1	0.1	-0.0	0.2	-0.4	0.3
Impedance of arm (right)	0.2	0.7	5.5	1.0	-0.7	0.7	-2.3	1.2	0.1	-0.0	0.5	1.0	0.6	-0.3	-0.2	0.5	0.7	-0.3	0.7	-0.9
Hip circumference	0.2	0.8	6.7	1.1	0.7	0.3	2.6	-1.2	0.7	0.8	0.1	-0.9	0.5	0.3	1.3	0.1	-0.3	0.6	0.0	0.2
Medication: Lansoprazole	0.2	0.2	1.2	0.2	0.3	0.4	1.1	0.1	-0.7	-0.6	-0.5	-0.0	0.0	0.9	-0.4	-0.1	0.1	0.5	-0.1	-0.1
Lung cancer (father)	0.2	0.3	1.7	-0.1	0.0	-0.0	1.3	0.7	-0.1	0.7	-0.3	-0.1	0.1	1.0	0.8	-0.0	-0.1	-0.5	0.5	-0.0
Impedance of arm (left)	0.2	0.7	6.0	1.2	-0.9	0.6	-2.5	0.8	0.2	0.2	0.5	0.8	0.5	-0.2	-0.2	0.6	0.6	-0.2	0.6	-0.9
Gout (self-reported)	0.2	0.2	2.3	-0.2	0.5	0.1	0.1	-0.6	0.2	0.3	-0.2	-0.5	-0.5	-0.4	1.5	0.2	-0.5	-0.1	-0.1	-0.3
Qualifications: College or University degree	0.2	0.6	2.3	-1.0	-1.5	-0.7	-0.7	0.2	-0.8	-0.1	-0.8	-0.1	-0.0	-0.3	-1.4	-0.2	-0.4	-1.1	-0.5	-0.4
Alcohol intake frequency.	0.2	0.5	2.0	1.4	1.3	0.1	-0.9	-0.5	-0.0	-0.5	0.0	-0.4	0.9	0.6	-0.1	-0.5	0.0	0.7	-0.3	1.1
Leg fat-free mass (right)	0.2	1.3	12.9	-0.6	1.1	-0.6	1.1	-3.6	0.7	-0.1	0.1	-0.8	-0.9	-1.1	1.2	-0.7	-0.5	0.2	-0.5	-0.4
Smoking status: Current	0.2	0.3	1.5	-0.2	0.2	-0.7	-0.9	-0.6	0.1	0.6	0.6	0.4	-0.8	-0.8	-0.1	0.2	0.5	-0.4	-0.0	-1.2
Leg predicted mass (right)	0.2	1.3	12.8	-0.5	1.1	-0.5	1.0	-3.6	0.8	-0.1	0.2	-0.7	-1.0	-1.2	1.2	-0.7	-0.5	0.1	-0.5	-0.4
Mother’s age at death	0.2	0.3	1.5	1.2	0.6	-0.6	-0.1	-0.6	-0.1	-0.2	-0.3	0.1	0.0	-0.9	-0.7	-1.0	-0.1	0.2	-0.1	-0.0
Average weekly beer plus cider intake	0.2	0.3	1.1	-1.0	-0.1	-0.8	-0.6	-0.1	-0.5	0.2	-0.2	-1.1	-0.1	-0.2	-1.0	-0.2	-0.1	-0.5	-0.8	-0.1
Risk taking	0.2	0.3	1.3	0.5	0.1	0.2	1.1	-0.5	-1.1	0.3	-0.1	-0.6	-0.9	0.5	-0.9	-0.3	-0.2	-0.3	-0.3	0.1
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.2	-0.8	-0.1	0.4	1.1	-0.5	-0.2	-0.8	0.1	0.2	-0.1	-0.2	1.1	0.2	-0.3	-0.5	-0.1	-0.1
Blood Eosinophil Count	0.1	0.9	4.5	-0.7	0.3	1.0	2.1	1.3	0.2	0.5	0.3	-0.2	1.3	-0.3	0.3	1.2	0.4	1.2	0.8	1.1
Blood Platelet Count	0.1	1.0	6.0	0.4	-1.2	-2.4	0.4	-1.5	-1.3	-1.1	-0.8	-0.1	1.5	-0.3	-1.0	-0.6	0.0	-0.4	-0.3	0.3
Heel T-Score	0.1	0.6	2.8	0.8	-0.3	1.7	0.8	1.1	0.7	1.3	0.4	-0.3	-0.3	0.9	0.5	0.2	0.5	-0.7	0.3	-0.2
Waist Hip Ratio (WHR)	0.1	0.6	1.9	-0.4	-0.2	-1.4	0.9	1.2	-0.7	0.4	-0.3	-0.5	-0.7	0.1	0.5	-0.4	-0.5	1.0	-0.7	-1.2
Tanning	0.1	0.9	4.0	-0.5	-0.4	-0.2	-1.2	-2.0	0.2	-0.8	0.7	1.6	-0.7	-0.7	-0.7	0.7	0.6	-1.5	1.1	-0.5
Taking other prescription medications	0.1	0.2	1.0	0.1	0.5	-0.2	0.9	-0.4	-0.1	-0.3	0.2	-0.0	1.0	-0.0	0.7	0.3	0.2	0.2	0.1	0.1
Mouth/teeth dental problems: Dentures	0.1	0.2	1.0	-0.4	-0.2	1.0	0.2	-0.2	-0.5	-0.4	-0.3	-0.2	0.5	0.7	-0.6	-0.1	-0.4	-0.0	-0.1	0.0
Pulse rate, automated reading	0.1	0.4	1.8	0.7	0.8	-0.8	0.4	1.1	0.6	0.5	0.7	0.1	-0.3	-0.6	0.7	-0.2	0.5	1.3	0.5	-0.2
Impedance of whole body	0.1	0.7	3.1	0.7	-0.9	0.5	-1.8	0.6	-0.1	0.2	0.7	1.3	0.2	-0.6	-0.8	0.7	0.7	-1.0	0.8	-1.0

Hub : Genes

CRYL1

Models

Trait associations