Best TWAS P=8.96e-23 · Best GWAS P=2.08e-47 conditioned to 2.49e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | C14orf39 | 0.08 | 0.05 | lasso | 8 | 0.06 | 2.1e-05 | 5.569 | -5.7 | 1.2e-08 | -0.41 | 0.92 | 0.02 | FALSE |
| 2 | GTEx | Esophagus Muscularis | C14orf39 | 0.10 | 0.02 | enet | 9 | 0.02 | 2.9e-02 | 0.079 | -5.4 | 5.1e-08 | -0.41 | 0.11 | 0.18 | TRUE |
| 3 | GTEx | Liver | MNAT1 | 0.21 | 0.00 | lasso | 4 | -0.01 | 5.4e-01 | 0.515 | -6.4 | 2.0e-10 | -0.44 | 0.08 | 0.20 | TRUE |
| 4 | GTEx | Muscle Skeletal | C14orf39 | 0.06 | 0.05 | lasso | 3 | 0.05 | 2.7e-05 | 5.569 | -9.4 | 6.9e-21 | -0.67 | 0.13 | 0.86 | FALSE |
| 5 | GTEx | Skin Not Sun Exposed Suprapubic | PCNXL4 | 0.15 | 0.05 | enet | 15 | 0.12 | 6.2e-07 | 2.869 | -9.8 | 9.0e-23 | -0.61 | 0.76 | 0.10 | TRUE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | C14orf39 | 0.02 | 0.02 | blup | 37 | 0.02 | 4.2e-03 | 5.554 | -8.1 | 5.5e-16 | -0.55 | 0.06 | 0.41 | FALSE |
| 7 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | C14orf39 | 0.08 | 0.05 | blup | 37 | 0.05 | 4.2e-03 | 5.563 | -7.6 | 3.1e-14 | -0.51 | 0.08 | 0.41 | FALSE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | C14orf39 | 0.08 | 0.09 | blup | 37 | 0.11 | 1.8e-11 | 5.691 | -7.4 | 1.1e-13 | -0.51 | 0.99 | 0.01 | FALSE |