Best TWAS P=1.52e-09 · Best GWAS P=1.89e-27 conditioned to 1.84e-20
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | RPL9P25 | 0.26 | 0.02 | enet | 27 | 0.07 | 1.3e-04 | -4.0 | -5.2 | 2.0e-07 | -0.13 | 0.72 | 0.02 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Male) | TIPIN | 0.44 | 0.10 | lasso | 24 | 0.16 | 1.4e-04 | -2.9 | -5.6 | 1.7e-08 | -0.28 | 0.18 | 0.41 | TRUE |
| 3 | GTEx | Cells EBV-transformed lymphocytes | SLC24A1 | 0.20 | 0.00 | lasso | 4 | -0.01 | 5.9e-01 | 5.0 | 6.0 | 1.5e-09 | 0.02 | 0.03 | 0.31 | TRUE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | TIPIN | 0.39 | 0.17 | enet | 15 | 0.22 | 1.9e-07 | -2.8 | -5.2 | 2.4e-07 | -0.03 | 0.00 | 0.02 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | SMAD3 | 0.06 | 0.06 | lasso | 2 | 0.06 | 2.5e-07 | 5.7 | 5.6 | 2.3e-08 | -0.06 | 0.90 | 0.03 | TRUE |