Best TWAS P=3.5e-10 · Best GWAS P=5.31e-11 conditioned to 0.0341
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Breast Mammary Tissue | MYO9A | 0.19 | 0.02 | lasso | 8 | 0.03 | 9.4e-03 | 3.7 | -5.8 | 6.1e-09 | -0.56 | 0.05 | 0.85 | FALSE |
2 | GTEx | Nerve Tibial | PARP6 | 0.09 | 0.07 | lasso | 11 | 0.06 | 7.2e-05 | 6.3 | 6.3 | 3.5e-10 | 0.90 | 0.03 | 0.95 | TRUE |