TWAS hub - MYO9A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0630	0.0280	3.1e-03	0.030	NA	-0.002	NA	0.010	1.6e-03	NA	5.5e-01	NA	4.7e-02
2	GTEx	Artery Tibial	0.0742	0.0264	2.5e-05	0.076	NA	0.087	NA	0.074	1.4e-06	NA	2.5e-07	NA	1.9e-06
3	GTEx	Brain Cerebellar Hemisphere	0.3310	0.1160	1.1e-03	0.072	NA	0.009	NA	0.026	6.4e-03	NA	1.9e-01	NA	7.0e-02
4	GTEx	Brain Cerebellum	0.1810	0.0880	6.4e-03	0.125	NA	0.026	NA	0.063	1.5e-04	NA	5.9e-02	NA	6.3e-03
5	GTEx	Breast Mammary Tissue	0.1920	0.0620	1.8e-04	0.022	NA	0.007	NA	0.032	2.5e-02	NA	1.3e-01	NA	9.4e-03
6	GTEx	Breast Mammary Tissue (Male)	0.1532	0.1288	1.7e-01	-0.013	NA	-0.007	NA	-0.013	8.7e-01	NA	4.8e-01	NA	9.3e-01
7	GTEx	Breast Mammary Tissue (Female)	0.1017	0.0669	5.8e-02	0.012	NA	0.000	NA	-0.004	1.4e-01	NA	3.1e-01	NA	4.5e-01
8	GTEx	Cells EBV-transformed lymphocytes	0.1350	0.0600	3.5e-03	0.085	NA	-0.005	NA	0.077	1.0e-03	NA	5.1e-01	NA	1.7e-03
9	GTEx	Cells Transformed fibroblasts	0.0590	0.0270	2.5e-03	0.039	NA	0.014	NA	0.027	6.4e-04	NA	3.1e-02	NA	3.8e-03
10	GTEx	Colon Transverse	0.1250	0.0570	4.6e-03	0.063	NA	0.060	NA	0.086	6.2e-04	NA	8.4e-04	NA	7.0e-05
11	GTEx	Nerve Tibial	0.1283	0.0414	1.3e-05	0.132	NA	0.106	NA	0.113	1.3e-09	NA	6.0e-08	NA	2.1e-08
12	GTEx	Skin Sun Exposed Lower leg	0.0950	0.0450	8.7e-03	0.009	NA	0.041	NA	0.012	5.3e-02	NA	2.2e-04	NA	3.2e-02
13	GTEx	Stomach	0.1700	0.1140	9.0e-03	0.061	NA	-0.006	NA	0.010	6.9e-04	NA	7.9e-01	NA	1.1e-01
14	YFS	Blood	0.0188	0.0066	2.1e-06	0.022	0.019	0.022	0.019	0.022	7.0e-08	4.9e-07	5.3e-08	3.8e-07	5.3e-08

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	8	9	10	11	12	13	14
Blood Red Count	7.1	68.4	132.2	11.0	10.3	2.0	7.5	11.5	10.3	9.1	5.0	11.5	3.2	9.8	9.3
Triglycerides	5.9	9.7	16.2	4.0	4.0	2.1	2.4	3.6	3.4	3.4	3.4	3.8	-0.3	3.9	4.0
Chronotype (morning person)	5.9	13.6	24.9	4.8	5.0	1.5	2.9	3.6	4.8	4.6	3.5	4.1	1.9	4.3	4.8
Forced vital capacity (FVC)	5.9	22.6	43.6	-5.8	-5.8	0.3	-4.7	-6.6	-5.6	-5.3	-3.8	-6.4	-2.2	-6.1	-5.1
Pulse rate	5.5	9.3	20.3	3.6	3.7	-1.3	3.1	4.0	3.2	3.3	4.5	3.9	1.2	3.2	2.9
Headache pain in last month	5.4	9.3	16.8	3.8	3.8	1.5	3.0	2.7	4.0	4.1	1.7	3.3	2.5	3.7	4.0
Forced vital capacity (FVC), Best measure	5.4	19.8	41.3	-5.5	-5.4	0.7	-4.3	-6.4	-5.2	-4.8	-4.2	-6.0	-2.0	-5.5	-4.6
Pulse rate, automated reading	5.4	17.4	33.6	5.2	5.2	-2.0	4.2	5.8	4.6	4.9	3.6	5.6	1.8	4.7	4.5
Hearing aid user	5.2	5.8	11.5	2.9	2.9	0.9	3.4	3.3	2.9	2.7	1.9	3.1	1.0	2.4	2.6
Medication: Paracetamol	5.1	7.8	13.1	3.6	3.5	0.6	1.6	3.2	3.4	3.6	2.2	3.5	2.3	3.2	3.5
Forced expiratory volume in 1-second (FEV1)	4.9	16.7	27.6	-4.9	-5.0	-2.7	-4.1	-5.2	-4.8	-4.2	-3.6	-5.2	-1.4	-5.2	-4.8
Forced expiratory volume in 1-second (FEV1), predicted	4.9	10.2	19.0	-3.8	-3.9	-0.9	-3.3	-4.4	-3.7	-3.1	-3.5	-4.1	-1.8	-4.1	-3.1
Pain experienced in last month	4.8	8.0	14.8	-3.4	-3.4	-2.6	-2.1	-2.5	-3.9	-3.7	-1.4	-3.1	-2.0	-3.7	-3.8
Forced expiratory volume in 1-second (FEV1), Best measure	4.7	14.9	24.2	-4.7	-4.6	-2.4	-3.8	-4.9	-4.6	-4.0	-3.9	-4.9	-1.2	-4.8	-4.5
Medication for cholesterol	4.7	7.1	14.0	-3.1	-3.3	-1.4	-2.2	-1.9	-3.6	-3.7	-2.8	-2.6	-0.1	-3.6	-3.7
Cholesterol lowering medication	4.6	6.7	11.6	3.2	3.2	0.5	2.6	2.9	3.3	3.2	1.9	3.2	1.6	3.4	3.0
Diastolic blood pressure, automated reading	4.3	13.4	22.7	4.7	4.6	-0.1	4.1	4.5	4.8	4.6	1.5	4.5	1.6	4.6	4.2
Standing height	3.9	38.5	103.0	-7.7	-7.3	-0.7	-5.9	-10.1	-7.2	-5.2	-5.2	-9.1	-3.8	-7.9	-4.8
Height	3.8	72.8	196.0	-10.9	-10.0	-0.8	-8.4	-14.0	-9.7	-7.0	-6.4	-12.6	-6.0	-10.5	-6.6
Medication: Paracetamol	3.8	6.3	10.0	3.1	3.2	0.6	2.1	2.8	3.0	3.0	2.2	3.0	2.5	2.8	3.1
Hearing difficulty/problems: Yes	3.7	5.7	10.8	3.0	3.0	-0.1	2.8	3.2	2.7	2.8	0.9	3.3	0.4	3.1	2.7
Number of treatments/medications taken	3.6	6.5	12.4	3.3	3.3	1.2	2.2	2.4	3.4	3.5	1.9	3.0	0.5	2.9	3.5
Comparative height size at age 10	3.6	20.1	47.9	-5.5	-5.2	-1.1	-3.8	-6.9	-5.1	-3.9	-4.5	-6.4	-3.7	-5.4	-3.9
High blood pressure (siblings)	3.5	5.1	10.1	3.1	3.1	-0.3	2.6	2.9	2.7	2.3	1.3	3.2	1.3	2.3	2.4
Medication: Atorvastatin	3.5	4.4	7.0	2.5	2.5	1.3	2.5	1.8	2.5	2.6	1.6	2.5	1.7	2.4	2.6
High cholesterol (Self-reported)	3.3	5.8	14.0	3.1	2.9	-0.3	2.3	3.1	2.7	3.0	0.9	3.7	0.1	3.1	2.7
Mouth/teeth dental problems: Dentures	3.2	5.3	12.0	3.0	2.8	1.2	1.5	2.4	2.7	3.3	0.3	3.1	1.0	2.6	3.5
Vascular/heart problems diagnosed by doctor	3.2	8.8	18.6	-3.6	-3.8	-0.2	-3.2	-2.6	-3.4	-4.3	-3.0	-3.2	-1.3	-3.7	-4.0
Illnesses of siblings	3.1	4.4	7.8	-2.6	-2.7	0.5	-2.6	-2.3	-2.2	-2.5	-1.3	-2.8	-1.7	-2.1	-2.6
High blood pressure	3.0	8.3	18.5	3.4	3.7	0.5	2.8	2.2	3.3	4.3	3.1	3.0	1.3	3.5	4.0
Financial difficulties in last 2 years	3.0	4.1	8.7	-2.7	-2.5	0.4	-2.8	-2.0	-2.4	-2.7	-0.4	-2.1	-0.3	-2.3	-2.9
Comparative body size at age 10	3.0	8.2	14.9	3.7	3.6	1.0	2.8	3.8	3.7	3.3	1.1	3.9	-0.3	3.8	3.1
Hypertension (Self-reported)	3.0	8.2	18.7	3.5	3.7	-0.1	2.5	2.3	3.2	4.3	3.0	3.1	1.1	3.5	4.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	3.0	3.5	8.2	2.5	2.5	-0.3	0.9	1.4	2.3	2.9	1.6	1.9	0.6	2.5	2.7
Average weekly fortified wine intake	2.9	3.4	6.3	-2.3	-2.5	-1.2	-1.6	-1.7	-2.3	-2.2	-1.3	-2.2	-0.4	-2.3	-2.5
Average weekly red wine intake	2.7	4.0	6.3	-2.4	-2.5	-0.7	-1.9	-2.1	-2.4	-2.2	-1.9	-2.3	-2.5	-2.3	-2.2
Serious illness, injury or assault to yourself	2.6	3.1	6.2	2.1	2.4	1.7	1.8	1.3	2.5	2.1	1.5	1.8	1.3	1.7	2.2
Medication: Blood pressure	2.6	4.9	9.7	2.8	2.8	0.4	1.7	1.9	2.8	3.1	1.7	2.4	0.9	3.1	3.1
BMI	2.5	14.5	34.1	5.2	4.8	-1.1	2.3	5.8	4.2	3.7	3.1	5.8	1.4	4.5	3.9
Severe depression (siblings)	2.5	2.8	9.1	-2.1	-2.2	-0.1	-3.0	-1.8	-1.9	-1.8	-1.7	-1.7	-0.9	-1.6	-1.6
Alcohol intake frequency.	2.5	5.8	9.9	2.5	2.7	3.1	2.9	2.1	3.0	2.5	3.1	2.4	0.9	2.8	2.2
Cardiovascular Disease	2.4	8.1	18.1	3.5	3.7	0.5	2.8	2.3	3.4	4.3	2.8	3.1	0.3	3.3	4.1
Medication: Simvastatin	2.4	3.6	7.4	2.2	2.2	-0.7	2.7	2.1	2.2	2.4	0.4	2.4	0.4	2.6	2.0
Arm fat percentage (left)	2.4	9.5	20.4	4.1	3.9	-0.7	1.7	4.2	3.7	3.5	1.1	4.5	1.9	3.9	3.7
Long-standing illness, disability or infirmity	2.4	3.7	10.0	2.3	2.3	1.0	1.5	1.2	2.6	3.1	0.2	2.1	0.9	2.3	3.2
Number of self-reported non-cancer illnesses	2.4	4.1	7.5	2.7	2.6	-1.1	1.5	2.4	2.2	2.7	0.8	2.7	1.2	2.3	2.6
Age when periods started (menarche)	2.2	5.4	13.2	-2.7	-3.0	-1.1	-3.6	-2.5	-3.0	-2.6	-1.3	-2.3	-1.0	-2.3	-3.0
Medication for pain relief, constipation, heartburn	2.2	3.7	8.9	-2.1	-2.3	-0.1	-1.4	-1.5	-2.2	-3.0	-2.4	-2.0	-1.2	-2.2	-2.8
Overall health rating	2.2	4.7	8.2	2.8	2.8	-0.9	1.2	2.6	2.6	2.9	1.7	2.9	1.8	2.3	2.5
Number of operations (self-reported)	2.2	3.3	12.0	2.4	2.4	0.4	0.2	2.1	1.8	1.8	3.5	2.5	0.2	1.5	1.9
Tinnitus: Yes, now most or all of the time	2.1	2.4	4.6	2.0	2.1	1.1	1.0	1.3	1.8	1.8	2.1	1.6	0.4	1.8	2.0
Lung FEV1/FVC ratio	2.0	10.2	132.2	0.2	-0.1	-11.5	-0.3	1.6	-0.3	2.2	-0.7	1.1	-0.7	-0.3	-0.7
Taking other prescription medications	2.0	3.1	6.4	2.2	2.1	-0.2	0.6	1.7	1.9	2.5	1.7	2.3	2.0	1.7	2.4
Arm fat percentage (right)	2.0	8.0	16.8	3.8	3.6	-0.5	1.6	3.7	3.4	3.3	0.8	4.1	1.9	3.6	3.4
Number of full brothers	2.0	2.5	4.8	1.9	1.8	1.5	1.5	1.3	1.9	1.6	1.2	1.7	2.2	1.9	1.8
Illnesses of siblings: Diabetes	2.0	2.4	4.2	1.8	2.0	-1.3	1.7	1.8	1.5	1.9	1.5	2.0	-0.3	1.6	1.9
Body mass index (BMI)	1.9	8.1	18.6	3.8	3.6	-0.7	1.7	4.1	3.4	3.1	1.1	4.3	1.3	3.6	3.1
Diverticular disease/diverticulitis (self-reported)	1.8	2.2	4.0	1.7	1.9	0.6	2.0	1.4	1.7	1.9	1.3	1.6	0.6	2.0	1.7
Father’s age at death	1.8	2.4	7.7	-1.7	-1.7	0.1	-1.3	-2.0	-1.9	-1.4	-0.4	-1.7	-2.8	-1.9	-1.3
Hypothyroidism/myxoedema (self-reported)	1.7	3.3	6.1	2.1	2.3	0.4	1.1	2.0	2.2	2.4	0.5	2.3	2.4	2.0	2.5
Medication: Ibuprofen	1.7	2.0	4.1	1.3	1.6	1.6	2.0	0.8	1.9	1.6	1.6	1.2	0.6	1.3	1.9
Mouth/teeth dental problems: Mouth ulcers	1.7	2.7	5.3	2.2	2.3	0.9	1.8	2.0	2.0	1.4	1.5	2.0	1.1	1.7	1.9
Medication: Bendroflumethiazide	1.7	2.6	4.5	2.1	2.1	0.7	2.1	1.6	2.0	2.1	-0.1	1.9	0.5	2.0	2.0
Lung FVC	1.6	7.9	17.0	-3.4	-3.5	0.8	-2.9	-3.0	-3.4	-4.1	-2.1	-3.2	-1.0	-3.1	-4.0
Other serious medical condition/disability diagnosed by doctor	1.6	2.1	4.2	1.8	1.9	1.0	1.7	1.2	1.8	1.9	0.5	1.6	-0.1	1.8	2.1
Hearing difficulty/problems with background noise	1.6	2.5	5.1	1.9	1.9	0.2	1.9	1.9	1.7	1.9	0.2	2.3	-0.4	2.3	1.9
Medication: Ibuprofen (e.g. Nurofen)	1.6	2.0	3.9	1.4	1.7	0.9	2.0	1.3	2.0	1.7	1.3	1.5	0.8	1.4	1.9
Myopia	1.6	2.4	6.1	-1.7	-1.7	-1.9	-2.5	-2.0	-1.6	-0.5	-1.8	-1.8	-1.0	-1.7	-0.9
Ever used hormone-replacement therapy (HRT)	1.5	2.0	4.9	1.7	1.5	-1.1	1.2	1.7	1.2	1.8	1.5	2.2	1.1	1.2	1.5
Heart attack	1.5	1.9	3.9	1.9	1.8	0.2	1.2	1.8	1.6	1.5	1.1	2.0	0.5	1.5	1.4
Peak expiratory flow (PEF)	1.5	3.4	13.4	-1.6	-1.8	-3.7	-1.5	-1.9	-1.6	-0.8	-2.6	-2.0	-1.1	-2.1	-1.8
Leg fat percentage (right)	1.5	5.3	12.7	3.1	2.8	-0.8	1.0	3.4	2.6	2.5	1.0	3.6	1.4	2.8	2.6
Osteoarthritis (self-reported)	1.5	1.9	4.5	1.7	2.0	0.4	1.2	1.1	1.5	1.7	1.5	1.4	-0.4	1.7	2.1
Ever had hysterectomy (womb removed)	1.4	1.5	3.1	1.6	1.6	-0.4	0.8	1.1	1.2	1.3	1.4	1.5	1.8	1.0	1.7
Mouth/teeth dental problems	1.4	2.1	4.7	-1.8	-1.8	-1.7	-2.1	-1.1	-1.6	-1.7	0.3	-1.5	-0.3	-1.3	-2.2
Hayfever/allergic rhinitis (self-reported)	1.4	1.9	4.9	1.7	1.7	-1.5	-0.2	1.7	1.2	1.5	2.2	1.9	0.9	0.7	1.5
Hand grip strength (left)	1.3	3.5	8.0	-2.1	-2.1	-1.0	-1.5	-2.2	-2.1	-1.9	-2.8	-2.0	-1.8	-2.3	-2.0
Eye problems/disorders: Diabetes related eye disease	1.3	1.4	3.1	1.6	1.4	-0.3	1.1	1.8	1.3	1.2	1.6	1.3	-1.2	1.2	0.9
Sitting height	1.3	8.9	33.8	-3.5	-3.0	0.6	-2.4	-5.8	-2.6	-1.8	-3.1	-5.0	-2.1	-3.6	-1.3
Medication: Ramipril	1.3	1.6	4.2	1.4	1.6	-1.3	1.2	0.4	1.2	2.1	1.7	1.3	-0.9	1.0	1.8
Medication for cholesterol, blood pressure or diabetes	1.3	2.2	5.8	-1.6	-1.7	-0.2	-2.1	-1.0	-1.7	-2.4	-0.7	-1.7	-0.5	-1.8	-2.1
Migraine (self-reported)	1.3	1.6	4.2	1.4	1.5	-0.9	1.0	0.6	1.1	1.5	2.0	1.1	2.0	1.0	1.5
Leg fat percentage (left)	1.3	4.8	11.8	2.9	2.7	-1.1	1.2	3.3	2.4	2.4	0.4	3.4	1.5	2.6	2.4
Hypothyroidism (self reported)	1.2	2.8	5.8	2.1	2.2	-0.3	0.8	2.2	1.9	2.3	-0.0	2.4	1.4	1.8	2.1
Supplements: Glucosamine	1.2	1.5	4.1	-1.4	-1.3	-2.0	-0.2	-0.9	-1.9	-1.4	-0.3	-1.0	-1.0	-1.8	-1.4
Trunk fat-free mass	1.2	6.6	21.9	-3.0	-2.8	-0.6	-3.1	-4.7	-2.8	-1.5	-2.4	-3.6	-1.9	-3.1	-1.4
Mouth/teeth dental problems: Bleeding gums	1.2	1.6	3.5	-1.5	-1.4	1.5	0.2	-1.9	-1.2	-1.5	-1.2	-1.9	-0.3	-1.5	-1.2
Body fat percentage	1.2	4.8	11.2	2.9	2.8	-1.0	1.1	3.1	2.4	2.5	0.8	3.4	1.4	2.6	2.6
Commuting to job workplace: Car/motor vehicle	1.2	1.3	6.2	-0.8	-0.9	-1.4	-0.7	-0.7	-1.0	-1.1	-2.5	-0.9	-1.5	-1.1	-1.2
Smoking status: Previous	1.2	1.8	6.0	1.8	1.6	-0.4	1.2	2.4	1.2	1.1	0.7	2.2	1.1	1.3	1.0
Schizophrenia (2014)	1.1	2.3	7.2	1.6	1.7	-1.0	1.0	1.2	1.2	2.3	1.9	2.0	0.1	1.5	2.7
Hand grip strength (right)	1.1	3.0	11.8	-1.7	-1.9	-0.7	-1.1	-1.3	-1.7	-1.8	-3.4	-1.4	-2.4	-1.7	-1.9
Hair/balding pattern: Pattern 3	1.1	1.6	5.1	-1.4	-1.6	1.2	-1.1	-0.9	-1.4	-2.3	-0.8	-1.5	-0.2	-1.1	-2.0
Trunk predicted mass	1.1	6.5	21.7	-2.9	-2.7	-0.7	-3.1	-4.7	-2.7	-1.5	-2.4	-3.6	-1.8	-3.0	-1.3
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	2.8	1.5	1.2	-0.8	1.2	1.6	0.9	1.3	-0.5	1.7	0.2	1.5	1.5
Commuting to job workplace: Walk	1.1	1.2	2.9	1.1	1.3	0.8	1.3	0.8	1.2	1.4	0.5	0.9	1.7	1.4	1.5
Schizophrenia (2018)	1.0	2.1	5.8	1.4	1.6	-0.6	1.2	1.4	1.0	2.0	2.3	2.0	-0.4	1.2	2.4
Medication for hormone replacement therapy	1.0	1.2	3.9	0.8	0.9	2.0	1.1	0.7	1.4	0.6	0.7	0.8	-1.8	1.4	0.9
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.1	2.5	-1.3	-1.2	-0.2	-1.3	-1.5	-1.2	-0.9	-0.9	-1.6	-0.8	-1.4	-0.9
Birth weight of first child	1.0	1.8	3.7	1.6	1.6	-0.5	0.8	1.5	1.3	1.3	1.9	1.6	1.2	1.9	1.3
Medication: Amlodipine	1.0	1.4	2.9	1.3	1.2	-1.2	0.8	1.3	0.8	1.7	1.0	1.5	1.7	0.9	1.7
Birth weight	1.0	2.2	5.2	1.9	2.2	0.3	2.1	1.0	1.8	1.9	0.5	1.3	0.8	1.6	2.3
Health satisfaction	1.0	1.3	3.1	1.6	1.7	-0.3	-0.1	0.7	1.4	1.7	0.5	1.2	-0.1	1.4	1.8
Back pain experienced in last month	1.0	1.5	4.9	1.1	1.2	2.2	1.1	0.6	1.7	1.4	-0.4	0.8	1.3	1.4	1.5
Medication: Gliclazide	1.0	1.1	3.3	0.7	1.1	-0.2	1.5	0.0	1.0	1.7	1.8	0.6	1.0	1.3	1.1
Arm fat mass (left)	1.0	3.9	8.2	2.7	2.6	-0.7	0.8	2.4	2.4	2.5	0.1	2.9	1.1	2.4	2.6
Medication: Lisinopril	1.0	1.2	2.6	1.1	1.4	1.3	0.8	0.4	1.4	1.5	1.5	0.7	0.2	1.6	1.4
Heart attack/myocardial infarction (self-reported)	1.0	1.2	2.8	1.5	1.5	-0.0	1.1	1.5	1.3	1.3	0.8	1.7	0.4	1.1	1.1
Heart disease (siblings)	1.0	1.2	2.4	1.1	1.2	0.3	1.5	0.7	1.2	1.4	1.1	1.3	1.2	1.0	1.6
Alcohol drinker status: Previous	1.0	1.2	4.2	1.1	1.2	0.8	0.6	1.2	1.3	1.2	2.0	0.9	-0.2	1.4	1.0
Bipolar Disorder or Schizophrenia	0.9	2.2	6.1	1.6	1.5	-0.5	0.9	1.2	1.1	2.1	1.8	2.4	-0.5	1.5	2.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.1	2.4	-1.3	-1.2	1.0	-0.9	-1.5	-1.2	-1.1	-0.5	-1.1	1.2	-1.4	-1.2
Medication: Levothyroxine sodium	0.9	1.6	4.7	1.3	1.4	1.2	0.5	0.8	1.4	1.8	-0.1	1.1	2.2	1.3	1.9
Impedance of leg (left)	0.9	4.4	8.6	-2.8	-2.7	-0.2	-1.2	-2.4	-2.7	-2.7	-1.2	-2.9	0.3	-2.9	-2.7
Qualifications: None of the above	0.9	2.0	5.5	1.6	1.7	-0.2	1.8	0.8	1.4	2.4	1.7	1.4	0.2	1.4	2.1
Gout (self-reported)	0.9	1.2	3.0	1.4	1.2	0.3	0.8	1.5	1.3	1.3	0.7	1.7	0.4	1.3	1.2
Medication: Blood pressure	0.9	1.6	4.6	1.3	1.5	-0.5	1.6	0.8	1.2	2.2	1.0	1.5	0.6	1.2	1.9
Medication: Allopurinol	0.9	1.2	2.3	1.1	1.1	-0.8	1.5	1.2	0.8	1.4	1.4	1.4	-0.5	1.1	1.1
Medication: Seretide 50 evohaler	0.9	1.0	3.1	-1.1	-1.2	0.6	-1.8	-1.4	-1.0	-0.5	-1.7	-1.2	0.3	-0.5	-0.5
Heart disease (mother)	0.9	1.1	3.2	1.5	1.1	0.1	0.9	1.8	1.3	0.7	-0.0	1.6	1.1	1.2	0.6
Ever had bowel cancer screening	0.9	1.1	3.2	-1.2	-1.1	-1.6	-1.8	-1.3	-1.5	-0.5	0.3	-1.0	0.6	-1.0	-0.4
Mineral and other dietary supplements	0.9	1.3	6.3	0.9	0.8	2.5	0.8	0.3	1.5	1.1	-0.6	0.9	-0.6	1.6	1.3
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.6	-1.4	-1.3	-0.9	-0.8	-0.9	-1.6	-1.4	0.3	-1.4	-0.6	-1.6	-1.5
Risk taking	0.9	1.2	5.8	0.9	0.5	-2.4	-0.8	1.9	-0.2	0.2	1.7	1.8	0.4	-0.1	0.0
Alzheimer’s Disease (in mother)	0.8	0.9	5.8	0.5	0.8	-0.2	1.1	0.3	0.7	1.3	0.8	0.5	-2.4	0.7	1.3
Alzheimer’s Disease (including proxy)	0.8	1.2	2.5	1.0	1.0	-0.5	0.9	1.4	1.2	0.9	1.3	1.4	-1.6	1.3	0.9
Smoking Status	0.8	1.8	5.1	1.8	1.5	-0.5	0.4	1.6	1.5	1.9	0.1	2.3	0.3	1.4	1.9
Trunk fat percentage	0.8	3.3	7.3	2.5	2.4	-0.9	0.7	2.4	2.0	2.2	0.5	2.7	1.1	2.1	2.4
Past tobacco smoking	0.8	1.4	5.0	-1.6	-1.3	0.3	-0.8	-2.2	-1.1	-0.9	-0.3	-2.2	-0.8	-1.1	-1.0
Had other major operations	0.8	1.0	4.4	1.2	1.2	-0.2	-1.0	1.0	0.9	0.6	0.9	1.1	2.1	0.7	0.9
Falls in the last year	0.8	1.1	3.6	1.0	1.1	0.8	-0.2	0.6	1.0	1.2	1.9	1.0	1.8	0.6	1.3
Number of live births	0.8	1.1	2.5	-1.3	-1.3	1.3	-1.1	-0.9	-0.8	-1.6	-0.3	-1.3	0.7	-0.7	-1.5
Arm fat mass (right)	0.8	3.3	6.6	2.5	2.4	-0.6	0.6	2.1	2.1	2.4	0.2	2.6	1.1	2.2	2.5
Exposure to tobacco smoke at home	0.8	0.9	4.0	-0.7	-1.1	0.5	-0.3	-0.1	-1.1	-2.0	-0.9	-0.3	-0.9	-0.8	-1.8
Pulse wave peak to peak time	0.8	0.9	3.8	-0.8	-0.9	-0.9	-1.9	-0.8	-0.8	-0.7	-1.5	-0.7	-0.5	-1.0	-0.8
Neck or shoulder pain in last month	0.8	1.1	3.2	1.1	1.0	-0.0	1.1	1.3	1.2	1.2	1.1	1.4	1.8	0.7	1.0
Number of full sisters	0.8	0.9	3.3	-1.1	-0.9	1.2	-0.7	-1.3	-0.5	-1.0	-0.1	-1.2	-1.8	-0.9	-0.9
Qualifications: nursing, teaching	0.8	1.2	2.6	-1.6	-1.4	0.7	0.3	-1.6	-1.4	-1.2	-1.2	-1.4	0.2	-1.2	-1.0
Wears glasses or contact lenses	0.8	0.9	3.4	0.8	0.9	1.8	-0.1	0.5	1.1	0.7	1.8	0.8	0.2	0.9	1.2
Eye problems/disorders: Glaucoma	0.8	0.9	4.9	0.8	0.6	-2.2	0.2	0.9	0.6	1.1	0.2	0.6	-1.9	0.5	0.4
Age started oral contraceptive pill	0.8	1.0	2.6	1.0	1.2	-0.7	1.3	0.5	0.7	1.6	1.0	0.6	0.8	1.1	1.6
Schizophrenia vs Biploar Disorder	0.7	0.9	2.5	1.1	1.3	-0.9	0.3	1.6	1.2	1.1	0.2	1.0	0.1	1.2	1.1
Prostate Cancer	0.7	0.9	2.1	-1.1	-0.9	0.6	-1.3	-1.4	-0.7	-1.2	-1.3	-1.4	-0.3	-0.4	-1.0
Coronary Artery Disease (CAD)	0.7	0.9	2.2	0.9	1.1	1.3	1.4	0.6	0.8	1.0	0.1	1.0	-0.3	1.5	1.1
Rheumatoid Arthritis	0.7	1.0	3.2	-1.4	-1.3	-0.1	-0.9	-1.8	-1.1	-0.7	-0.1	-1.6	-0.5	-1.1	-0.9
Systolic blood pressure, automated reading	0.7	2.0	4.4	1.8	1.8	0.3	0.9	1.3	1.8	2.1	0.5	1.5	1.0	1.8	2.1
Supplements: Zinc	0.7	0.7	1.9	1.2	1.1	0.6	0.8	1.4	1.0	0.7	0.6	1.0	0.1	1.2	0.4
Impedance of leg (right)	0.7	3.3	6.5	-2.4	-2.4	0.0	-1.4	-2.0	-2.3	-2.4	-0.5	-2.5	0.2	-2.5	-2.3
Stomach or abdominal pain in last month	0.7	0.8	5.4	-0.4	-0.5	-0.1	-2.3	-0.7	-0.2	-0.0	-2.0	-0.5	-0.9	-0.2	-0.1
Waist circumference	0.7	2.6	5.0	2.2	2.2	-0.2	0.6	1.8	1.9	2.1	0.8	2.2	0.9	2.0	2.2
Diabetes (self-reported)	0.7	1.0	5.5	-1.0	-1.0	-1.3	0.2	-0.3	-1.1	-0.7	1.3	-0.3	-2.3	-0.6	-1.2
Time employed in main current job	0.7	0.8	5.2	-0.8	-1.0	0.4	0.3	-0.3	-0.8	-1.0	-0.9	-0.8	-2.3	-0.6	-0.8
Medication: Lansoprazole	0.7	0.8	5.6	0.8	0.8	-0.2	0.1	1.1	0.5	0.8	2.4	1.0	-0.4	0.6	0.8
Chronic bronchitis/emphysema (mother)	0.7	0.8	3.2	-0.9	-0.8	1.8	0.7	-0.2	-0.4	-1.7	-0.7	-0.7	0.2	-0.4	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	3.5	1.2	1.1	-0.0	0.3	1.4	1.0	0.9	1.9	1.0	0.2	0.7	0.8
Knee pain experienced in last month	0.7	1.1	2.5	1.2	1.1	0.7	0.8	1.2	1.1	1.4	0.4	1.6	1.1	1.1	1.4
Whole body fat-free mass	0.7	4.0	13.9	-2.2	-2.0	-0.5	-2.7	-3.7	-2.0	-1.0	-2.2	-2.8	-1.5	-2.3	-0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	2.5	-1.2	-1.2	-1.4	-1.5	-1.3	-1.4	-1.2	0.4	-1.3	0.8	-1.5	-1.6
Average weekly champagne plus white wine intake	0.7	1.0	2.5	-1.0	-1.4	-0.3	-1.1	-0.8	-1.5	-1.2	0.2	-1.1	-1.0	-1.6	-1.2
Alcohol drinker status: Never	0.7	0.8	2.2	-1.1	-0.9	1.4	-0.5	-1.5	-0.7	-0.5	-0.6	-1.2	0.9	-0.9	-0.8
Irritability	0.7	1.2	7.0	-0.5	-0.7	-1.8	-0.6	-0.1	-0.8	-0.9	0.7	-0.5	2.6	-1.4	-1.0
Lupus	0.6	1.0	2.1	-1.0	-1.3	-0.2	-1.4	-0.0	-1.3	-1.4	0.4	-0.5	0.9	-1.5	-1.3
Allergy or Eczema	0.6	1.7	3.9	1.6	1.6	0.9	0.4	1.2	1.8	1.8	0.9	1.6	0.4	1.6	2.0
Type 2 Diabetes (T2D) (2018)	0.6	1.2	2.4	-1.4	-1.3	-1.5	-0.3	-0.9	-1.6	-1.1	0.3	-0.6	-1.2	-1.5	-1.3
Medication: Atenolol	0.6	0.7	2.3	0.5	0.4	-0.3	1.0	1.4	0.6	0.5	-1.1	1.3	-1.5	0.9	0.3
Medication: Cholesterol lowering	0.6	0.9	3.0	0.9	1.0	-0.0	1.7	0.6	0.9	1.4	-0.1	1.3	-0.3	1.1	1.4
Lung cancer (father)	0.6	0.7	1.7	0.8	0.9	-0.2	1.3	0.9	0.7	0.5	-0.4	1.1	1.3	0.9	0.9
Length of working week for main job	0.6	0.7	2.1	0.8	0.7	-1.0	0.9	1.1	0.8	1.2	0.7	1.5	0.5	0.4	0.9
Eye problems/disorders: None of the above	0.6	0.7	2.1	-1.0	-0.8	0.9	-1.2	-0.9	-0.6	-0.9	0.1	-1.0	1.5	-0.4	-0.7
Leg fat mass (right)	0.6	2.4	5.5	2.1	2.0	-1.0	0.3	1.9	1.8	2.0	0.2	2.3	0.7	1.9	2.1
Suffer from ‘nerves’	0.6	1.0	3.8	-1.1	-1.1	-0.2	-1.9	-1.5	-1.0	-0.8	-0.4	-1.3	-0.3	-1.1	-0.7
Family relationship satisfaction	0.6	0.7	6.6	-0.2	-0.1	-2.6	-0.3	-0.5	-0.8	0.5	1.0	-0.1	-0.2	-0.8	-0.1
Supplements: Vitamin C	0.6	0.7	2.8	-0.9	-1.0	-0.2	-0.3	-0.1	-1.0	-1.2	-0.3	-0.9	1.3	-0.7	-1.7
Friendships satisfaction	0.6	0.7	5.3	-0.8	-0.6	-2.3	-0.4	-1.0	-0.7	0.0	0.1	-0.6	0.3	-1.2	-0.4
Eye problems/disorders: Cataract	0.6	0.7	3.1	0.8	0.7	0.8	1.8	1.2	0.7	0.3	-0.2	0.8	-1.0	0.7	0.5
Whole body water mass	0.6	3.5	12.5	-2.0	-1.8	-0.6	-2.5	-3.5	-1.9	-0.8	-2.0	-2.6	-1.4	-2.2	-0.6
Ever taken oral contraceptive pill	0.6	0.7	3.7	-1.1	-0.9	0.4	-0.8	-1.9	-0.6	0.0	-0.7	-1.1	-0.3	-0.7	0.1
Illnesses of father: High blood pressure	0.6	0.7	4.8	0.0	-0.2	-0.9	-0.8	-0.4	0.0	0.3	-2.2	-0.1	-1.7	-0.5	0.1
Basal cell carcinoma (self-reported)	0.6	0.7	2.7	-0.8	-0.7	0.7	-0.9	-1.6	-0.1	-0.4	0.3	-1.6	-1.6	-0.6	-0.2
Pack years of smoking	0.6	0.9	1.9	1.2	1.3	-0.6	1.1	0.8	0.8	1.2	0.8	1.1	0.4	0.8	1.4
Leg fat mass (left)	0.6	2.2	4.9	2.0	1.9	-1.0	0.4	1.8	1.6	1.9	-0.1	2.2	0.7	1.7	1.9
Alzheimer’s Disease (in father)	0.5	0.5	2.6	0.3	0.0	-0.8	-0.6	1.6	0.2	-0.6	0.7	0.9	0.8	0.8	-0.8
Crohns Disease (2012)	0.5	0.8	2.2	-1.0	-0.7	1.3	-0.8	-1.3	-0.5	-1.0	0.5	-1.5	-1.3	0.1	-0.9
Fasting Glucose	0.5	0.5	1.8	-0.3	-0.4	1.1	-1.3	0.7	-0.5	-1.3	0.9	0.2	0.0	-0.4	-0.9
HbA1C	0.5	0.5	1.3	-0.6	-0.8	-0.1	-0.6	-0.8	-0.9	-0.8	-1.1	-0.9	0.8	-0.9	-0.9
HDL Cholesterol	0.5	0.8	1.9	-0.9	-1.2	-0.5	-1.1	-0.6	-0.6	-0.9	-1.4	-0.8	-0.8	-0.9	-1.2
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.8	0.9	0.6	-1.2	-0.4	1.3	0.3	0.2	0.9	1.3	-1.1	0.7	-0.2
Average weekly spirits intake	0.5	0.6	5.1	0.3	0.5	1.0	2.3	0.6	0.4	-0.0	-0.9	0.2	-0.1	0.3	0.3
Chronic bronchitis/emphysema (father)	0.5	0.6	2.4	1.0	1.2	0.2	0.6	0.3	0.6	1.2	0.4	0.8	0.7	0.7	1.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.8	1.9	-1.0	-1.1	-0.4	-1.4	-0.5	-1.3	-1.2	-0.6	-0.3	0.3	-1.2	-1.2
Allergy	0.5	1.3	3.3	-1.4	-1.3	-1.8	-0.3	-0.8	-1.5	-1.3	-0.7	-1.1	-0.6	-0.9	-1.8
Fluid intelligence score	0.5	1.0	5.3	-0.5	-0.5	-1.3	-0.3	-0.8	-0.6	0.0	-2.1	-0.8	2.3	-0.7	-0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	9.3	-0.2	-0.4	1.0	-0.3	-0.4	-0.1	0.1	-3.0	0.1	-0.4	-0.4	0.3
Loud music exposure frequency	0.5	0.6	2.0	0.8	0.8	0.0	-0.2	1.4	1.0	0.6	0.5	1.4	-0.1	0.7	0.7
Qualifications: O levels/GCSEs or equivalent	0.5	0.7	2.1	-1.0	-1.0	-0.1	-1.0	-1.2	-1.0	-0.9	-0.2	-1.4	0.2	-1.0	-1.0
Glaucoma (self-reported)	0.5	0.5	2.8	0.5	0.6	-1.1	0.3	-0.1	0.6	1.2	0.6	-0.0	-1.7	0.4	0.8
Age at last live birth	0.5	0.8	1.6	-1.1	-1.2	-0.8	-1.0	-1.0	-1.0	-0.9	-0.3	-1.0	-0.7	-1.0	-0.9
Commuting to job workplace: Public transport	0.5	0.6	1.1	-1.0	-1.0	0.5	-1.1	-0.8	-0.7	-0.8	-0.3	-0.8	0.6	-1.0	-0.6
Basal metabolic rate	0.5	2.6	9.0	-1.7	-1.6	-0.6	-2.4	-3.0	-1.6	-0.7	-2.0	-2.1	-1.2	-1.9	-0.5
Arm fat-free mass (left)	0.5	2.6	8.4	-1.6	-1.5	-0.9	-2.2	-2.9	-1.7	-0.7	-1.8	-2.1	-1.2	-2.0	-0.5
Supplements: Calcium	0.5	0.5	1.2	0.8	0.8	-0.0	0.6	0.7	0.8	1.1	1.1	0.7	0.5	0.7	1.1
Arm predicted mass (left)	0.5	2.6	8.7	-1.7	-1.5	-0.9	-2.2	-3.0	-1.7	-0.7	-1.5	-2.2	-1.1	-2.1	-0.6
Verbal and Numeric Reasoning (VNR)	0.4	0.9	5.3	-0.7	-0.5	-1.2	-0.0	-1.0	-0.7	-0.3	-1.3	-1.1	2.3	-0.8	-0.6
Body Mass Index (BMI) (2010)	0.4	0.5	1.6	0.9	0.9	0.1	0.2	1.3	0.6	0.4	0.9	1.2	-0.5	0.6	0.5
Angina	0.4	0.5	2.0	0.4	0.4	0.9	1.4	1.2	0.4	-0.3	-0.1	1.1	-0.2	0.8	-0.0
Diabetes (father)	0.4	0.5	3.6	-0.5	-0.7	0.1	-1.9	0.1	-0.8	-1.1	0.2	-0.1	-0.2	-0.8	-0.7
Pack years adult smoking proportion	0.4	0.7	1.4	1.1	1.1	-0.8	0.9	0.6	0.6	1.2	0.7	0.9	0.5	0.6	1.2
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	2.9	-0.1	0.1	-1.1	-1.0	-0.4	-0.3	0.3	1.7	0.2	1.0	-0.5	0.4
Hayfever, allergic rhinitis or eczema	0.4	0.9	2.2	1.2	1.1	0.6	-0.0	0.7	1.2	1.3	0.8	1.2	-0.2	1.0	1.5
Nervous feelings	0.4	0.8	3.8	-0.9	-0.9	0.5	-2.0	-1.1	-0.9	-0.6	0.9	-0.6	-1.1	-0.9	-0.5
Had menopause	0.4	0.5	1.1	0.9	0.9	0.8	0.2	0.7	0.9	0.7	0.1	0.5	0.1	1.1	1.1
Depression (self-reported)	0.4	0.5	2.7	0.3	0.1	0.5	1.0	-0.3	0.2	0.5	-1.7	0.2	-1.5	0.6	0.4
Arm fat-free mass (right)	0.4	2.1	6.6	-1.5	-1.4	-0.9	-1.9	-2.6	-1.5	-0.6	-1.6	-1.9	-1.1	-1.8	-0.5
Wheeze or whistling in the chest in last year	0.4	0.8	3.4	0.9	0.8	1.0	-0.2	1.1	0.5	-0.1	1.1	1.1	-1.8	0.8	0.7
Age at first live birth	0.4	0.6	1.8	-1.1	-1.0	-1.0	0.1	-1.2	-1.1	-0.5	0.0	-1.4	-0.1	-0.6	-0.6
Emphysema/chronic bronchitis	0.4	0.5	1.2	-1.1	-1.0	0.8	-0.4	-1.1	-0.7	-0.9	0.2	-0.8	-0.4	-0.5	-0.5
Whole body fat mass	0.4	1.7	3.6	1.7	1.6	-1.1	-0.0	1.4	1.3	1.8	-0.1	1.9	0.5	1.4	1.9
Arm predicted mass (right)	0.4	2.3	7.2	-1.5	-1.4	-1.0	-1.9	-2.7	-1.6	-0.5	-1.7	-2.0	-1.5	-1.9	-0.5
Average weekly beer plus cider intake	0.4	0.6	1.7	-0.9	-0.6	1.0	-0.2	-1.2	-0.7	-0.7	0.2	-1.3	1.0	-0.6	-0.8
Unable to work because of sickness or disability	0.4	0.5	2.2	0.5	0.7	0.1	-0.3	-0.1	0.6	1.5	1.1	0.1	-0.5	0.7	1.3
Impedance of whole body	0.4	2.3	5.2	-2.0	-1.9	0.1	-1.0	-2.0	-1.8	-1.7	-1.0	-2.3	0.0	-2.1	-1.6
Ovarian Cancer	0.3	0.5	1.4	-0.1	-0.2	-1.0	-1.2	0.4	-0.6	-0.6	1.2	-0.3	0.4	-0.8	-1.0
Age at First Birth	0.3	0.4	1.7	-0.2	-0.1	-1.1	0.7	-0.9	-0.8	-0.0	-0.2	-0.6	-1.3	0.1	-0.2
Primary Biliary Cirrhosis	0.3	0.5	3.0	0.1	0.2	1.7	-0.4	-0.2	0.4	0.1	-1.5	-0.2	-0.4	0.5	0.6
Blood Platelet Count	0.3	3.7	7.2	-2.0	-2.3	-2.3	-2.5	-1.0	-2.7	-2.4	-1.3	-1.1	-0.1	-2.5	-2.6
Heel T-Score	0.3	2.1	11.3	-0.0	-0.1	-0.3	0.7	2.2	-0.6	-1.9	1.6	1.1	3.4	-1.3	-1.8
Systolic Blood Pressure	0.3	1.6	4.9	1.5	1.6	0.4	0.8	0.5	1.7	2.2	0.2	0.7	1.2	1.6	2.2
Relative age of first facial hair	0.3	0.6	3.6	0.7	0.6	1.9	-0.3	0.5	1.1	0.1	0.6	0.1	-0.9	1.0	0.6
Medication: Co-codamol	0.3	0.4	1.6	0.4	0.3	-0.8	0.9	1.3	0.4	-0.2	0.1	0.9	0.4	0.6	-0.3
Medication: Metformin	0.3	0.4	3.5	-0.2	-0.2	-1.1	-0.1	0.1	-0.5	0.1	1.9	0.4	0.6	-0.3	-0.1
Diabetes (mother)	0.3	0.4	1.0	-0.4	-0.5	0.1	-0.7	0.1	-0.8	-1.0	0.3	-0.2	1.0	-0.9	-0.7
Maternal smoking around birth	0.3	0.5	1.7	0.6	0.4	0.5	0.0	1.1	0.6	0.2	-1.3	1.0	-0.8	1.0	0.2
Trunk fat mass	0.3	1.5	3.8	1.6	1.6	-1.1	-0.1	1.1	1.3	1.8	-0.2	1.7	0.4	1.3	1.9
Number of incorrect matches in round	0.3	0.5	2.2	0.6	0.4	0.5	-0.3	0.5	0.7	0.9	1.5	0.5	-0.9	0.9	0.9
Hair/balding pattern: Pattern 2	0.3	0.4	1.1	0.6	0.5	-0.2	1.1	0.8	0.5	0.6	-0.7	0.8	0.6	0.4	0.5
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	3.3	-0.3	-0.3	1.8	0.3	-0.0	-0.4	-0.8	-0.3	0.3	0.4	-0.5	-0.6
Impedance of arm (right)	0.3	1.4	4.2	-1.5	-1.3	0.3	-0.8	-2.0	-1.2	-0.9	-1.0	-2.0	0.2	-1.6	-0.7
Happiness	0.3	0.4	1.1	-0.7	-0.6	-0.7	-0.1	-1.1	-0.7	-0.6	-0.1	-0.9	0.1	-0.9	-0.8
Qualifications: A levels/AS levels or equivalent	0.3	0.6	2.7	0.1	0.4	-0.4	0.2	-1.3	0.3	1.7	0.2	-0.9	0.5	0.2	1.4
Breastfed as a baby	0.3	0.3	1.1	0.8	0.8	-0.2	-0.0	0.7	0.5	0.4	1.0	0.5	0.7	0.6	0.3
Hair/balding pattern: Pattern 4	0.3	0.7	5.3	-0.2	-0.1	-1.3	-0.6	-0.6	-0.4	0.8	0.7	-0.1	-2.3	-0.5	0.4
Exposure to tobacco smoke outside home	0.3	0.4	2.6	-0.1	-0.0	-0.0	1.6	0.9	-0.0	-0.8	0.0	0.4	-0.9	0.0	-0.7
Qualifications: College or University degree	0.3	0.8	1.9	-1.2	-1.0	-0.7	-0.5	-1.4	-0.9	-0.2	-0.9	-1.4	-1.0	-1.2	-0.1
Angina (self-reported)	0.3	0.4	1.8	0.4	0.4	0.7	1.3	1.2	0.3	-0.2	0.1	1.1	-0.1	0.6	-0.0
Chest pain or discomfort	0.3	0.5	1.6	0.8	0.7	-0.2	1.3	0.9	0.5	0.2	-0.6	1.0	-0.7	0.7	0.4
Had major operations	0.3	0.4	3.1	-0.2	-0.1	0.9	-0.8	-0.2	-0.1	-0.5	1.8	-0.0	0.3	-0.1	-0.3
Leg pain on walking	0.3	0.4	2.5	0.6	0.7	-0.1	-0.3	1.1	0.6	-0.1	1.6	0.5	0.4	0.4	0.0
Leg fat-free mass (right)	0.3	1.7	6.2	-1.2	-1.1	-0.4	-1.8	-2.5	-1.1	-0.3	-2.1	-1.7	-1.1	-1.4	-0.2
Diabetes diagnosed by doctor	0.3	0.5	2.1	-0.2	-0.3	-1.4	0.5	0.4	-0.6	-0.2	1.4	0.4	-1.4	-0.2	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	2.6	-0.2	-0.4	0.3	-0.6	0.1	0.3	-0.2	-1.6	0.0	-1.2	0.1	-0.2
Breast cancer (self-reported)	0.3	0.3	1.6	0.1	0.2	1.2	-0.2	-0.5	0.3	0.2	0.8	-0.4	1.3	-0.2	0.6
Illnesses of father: None of the above (group 1)	0.3	0.4	1.6	-0.5	-0.5	-0.6	0.0	0.4	-0.8	-1.1	0.5	-0.2	-0.5	-0.4	-1.3
Leg predicted mass (right)	0.3	1.7	6.2	-1.2	-1.1	-0.4	-1.7	-2.5	-1.0	-0.3	-2.1	-1.7	-1.2	-1.4	-0.2
Miserableness	0.3	0.4	2.8	0.7	0.6	-0.4	0.6	0.9	0.4	0.2	0.6	0.7	1.7	0.3	0.2
Guilty feelings	0.3	0.4	1.5	-0.3	-0.3	-1.1	-0.6	-0.3	-0.7	-0.4	0.8	-0.1	1.2	-0.6	-0.5
Mother’s age at death	0.3	0.4	1.2	-0.5	-0.6	-0.6	-0.6	0.5	-0.7	-0.6	1.1	0.1	-0.5	-1.0	-0.6
Pain type(s) experienced in last month: Hip pain	0.3	0.3	1.3	0.7	0.5	0.1	-0.4	1.0	0.7	0.3	-0.4	1.1	0.2	0.8	0.3
Bipolar Disorder (2018)	0.2	0.3	0.9	0.7	0.5	-0.0	-0.2	0.4	0.5	0.9	0.0	0.9	-0.2	0.8	1.0
Depressed Affect (Nagel 2018)	0.2	0.4	2.1	0.7	0.7	-0.7	0.3	0.7	0.5	0.3	-0.4	0.7	1.4	0.9	0.2
Crohns Disease (2017)	0.2	0.4	1.6	-0.4	-0.3	1.3	-0.7	-1.0	-0.2	-0.4	-0.9	-0.9	-0.9	-0.2	-0.4
Irritable Bowel Disease (IBD)	0.2	0.4	2.6	-0.1	0.2	1.6	-0.4	-1.1	0.2	0.2	-0.6	-0.5	-0.6	0.2	0.4
Ulcerative Colitis (UC)	0.2	0.4	1.2	0.6	0.8	1.1	0.0	-0.4	0.7	1.0	0.0	0.3	-0.0	0.7	1.1
Major Depression (MDD)	0.2	0.3	0.6	0.5	0.5	0.7	0.6	0.3	0.8	0.5	0.6	0.6	-0.3	0.7	0.7
Bipolar Disorder (2011)	0.2	0.2	1.3	-0.2	-0.4	1.0	0.2	-0.1	-0.0	-0.6	-1.1	-0.1	0.0	-0.6	-0.2
Mean Putamen Volume	0.2	0.3	1.2	0.1	0.3	1.0	1.1	0.4	0.8	0.1	-0.3	0.0	-0.4	0.2	0.3
LDL Cholesterol	0.2	0.3	1.5	0.4	0.5	0.8	0.5	-0.3	0.6	0.6	1.2	-0.2	0.4	0.5	0.8
Ulcerative Colitis	0.2	0.3	1.3	0.1	0.3	1.1	0.4	-0.4	0.3	0.4	-0.9	0.2	-0.2	0.5	0.8
Blood Eosinophil Count	0.2	1.2	4.0	1.1	1.4	-0.9	0.8	-0.0	0.9	1.9	1.7	0.8	-0.5	0.6	2.0
Respiratory disease	0.2	0.4	3.8	-0.0	-0.0	1.9	0.6	0.1	0.3	-0.8	-0.6	-0.2	0.2	0.1	-0.1
Leg fat-free mass (left)	0.2	1.3	4.7	-1.0	-0.9	-0.4	-2.0	-2.2	-0.8	-0.1	-1.6	-1.4	-1.1	-1.1	0.0
Current tobacco smoking	0.2	0.3	1.1	-0.1	-0.1	0.0	-0.9	-1.1	0.1	0.8	-0.5	-0.2	-0.5	0.1	0.7
Fed-up feelings	0.2	0.3	2.9	-0.3	-0.3	-0.8	0.2	-0.1	-0.2	-0.3	0.5	-0.0	1.7	-0.1	-0.5
Multivitamins +/- minerals	0.2	0.3	1.4	-0.0	-0.0	-0.8	-0.4	0.3	-0.4	-0.6	0.6	0.0	1.2	-0.5	-0.6
Leg predicted mass (left)	0.2	1.2	4.7	-0.9	-0.8	-0.3	-1.9	-2.2	-0.8	-0.0	-1.6	-1.3	-1.1	-1.1	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.5	2.0	0.2	-0.0	-0.5	0.8	0.9	0.1	-0.6	-1.4	0.8	1.2	-0.1	-0.6
Pain all over the body in last month	0.2	0.2	0.5	0.4	0.5	0.4	0.2	0.7	0.6	-0.2	0.7	0.5	0.4	0.6	-0.2
Neuroticism score	0.2	0.5	1.2	-0.6	-0.7	-0.6	-0.9	-1.0	-0.8	-0.7	0.3	-0.7	1.0	-1.1	-0.8
Alcohol intake versus 10 years previously	0.2	0.4	1.0	0.4	0.5	0.2	-0.5	0.5	0.5	0.9	0.7	1.0	-0.9	0.5	0.7
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	0.9	-0.5	-0.5	0.4	-0.1	-0.1	-0.6	-0.9	-0.7	-0.2	0.8	-0.4	-0.9
Asthma	0.2	0.3	2.0	0.5	0.2	1.2	0.4	0.5	0.5	-0.0	-1.4	0.3	0.2	0.3	0.4
Illnesses of mother	0.2	0.2	1.1	-0.5	-0.4	-0.6	-0.0	-1.1	-0.7	0.0	-0.8	-0.6	-0.2	-0.3	-0.1
Pulse wave Arterial Stiffness index	0.2	0.2	1.6	0.0	0.2	0.6	1.3	-0.1	0.1	0.2	0.9	-0.1	0.3	0.4	0.3
Impedance of arm (left)	0.2	0.9	2.1	-1.3	-1.1	0.2	-0.8	-1.4	-1.0	-0.9	-0.9	-1.4	0.1	-1.4	-0.7
Pulse wave reflection index	0.2	0.2	1.8	-0.0	-0.1	1.0	1.4	-0.2	-0.2	-0.3	-0.2	-0.3	0.1	-0.0	-0.1
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.5	0.1	0.2	1.2	-0.1	0.3	0.4	0.3	-0.5	0.7	-1.0	-0.1	0.4
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.7	0.2	0.1	0.8	0.6	0.6	0.3	-0.4	-0.8	0.6	-0.8	0.1	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.2	2.2	-0.3	-0.2	-0.3	-0.2	-0.4	-0.1	0.3	-1.5	-0.1	-0.4	-0.4	0.2
Number of children fathered	0.2	0.2	1.0	0.5	0.5	-0.1	-0.0	0.5	0.4	0.4	-0.1	0.8	1.0	0.6	0.4
Shortness of breath walking on level ground	0.2	0.3	1.2	0.4	0.5	0.7	-0.2	0.1	0.4	0.3	1.1	0.4	0.8	-0.1	0.6
Medication: Omeprazole	0.2	0.2	1.0	0.5	0.4	0.3	-0.1	0.5	0.6	0.6	0.2	0.6	-1.0	0.4	0.4
Mean time to correctly identify matches	0.2	0.3	1.7	-0.3	-0.5	-0.2	-0.9	-0.1	-0.5	-0.7	1.3	-0.5	0.0	0.3	-0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.0	0.3	0.5	0.3	1.0	0.8	0.7	-0.3	0.5	0.4	-0.6	0.8	-0.1
Asthma (self-reported)	0.2	0.4	2.9	0.2	-0.0	1.4	0.2	0.3	0.4	-0.3	-1.7	0.0	0.2	0.2	0.1
Osteoporosis (self-reported)	0.2	0.2	1.5	-0.1	-0.6	-0.3	-0.3	0.2	-0.2	-0.5	-1.2	-0.0	-0.2	-0.4	-0.6
Financial situation satisfaction	0.2	0.3	2.1	0.2	0.2	0.7	-0.7	0.3	0.2	-0.3	1.4	0.4	0.3	0.0	-0.3
Fractured/broken bones in last 5 years	0.2	0.3	1.1	-0.2	-0.0	0.7	-0.1	-1.0	-0.2	0.8	0.6	-0.2	0.1	-0.5	0.9
Commuting to job workplace: Cycle	0.2	0.3	1.9	-0.0	0.0	1.4	0.2	0.5	0.1	-0.7	-0.2	0.1	1.1	0.0	-0.4
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.7	0.0	0.1	0.1	0.1	0.1	0.0	0.2	1.3	0.2	-0.9	-0.1	0.1
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	1.7	0.2	-0.1	-0.6	-1.3	0.5	-0.3	-0.2	0.2	0.4	-0.2	-1.0	-0.4
Intelligence (Savage-Jansen 2018)	0.1	0.4	2.6	-0.2	-0.2	-1.1	-0.8	-0.3	-0.5	-0.6	0.1	-0.2	1.6	-0.4	-0.6
Neuroticism (Nagel 2018)	0.1	0.3	1.9	0.4	0.3	-0.6	-0.8	0.3	0.3	0.1	-0.2	0.3	1.4	0.3	-0.0
Reaction Time	0.1	0.3	1.3	-0.2	-0.4	0.7	-0.6	-0.0	-0.3	-0.7	1.1	-0.5	0.3	0.4	-0.7
Breast Cancer	0.1	0.2	1.2	0.6	0.3	-0.4	-0.6	1.1	0.4	-0.1	-0.3	0.7	0.3	-0.0	-0.4
Neuroticism (2016)	0.1	0.2	0.8	-0.2	-0.3	0.2	-0.5	-0.4	-0.2	-0.3	0.9	-0.7	-0.1	-0.3	-0.5
Waist Hip Ratio (WHR)	0.1	0.4	4.1	0.1	-0.1	-2.0	-0.5	-0.3	-0.4	0.9	0.4	0.0	0.1	-0.5	0.3
Neuroticism	0.1	0.1	0.7	0.2	0.2	-0.7	-0.4	-0.3	0.1	0.2	0.5	0.1	0.9	-0.0	0.1
Sensitivity / hurt feelings	0.1	0.2	1.0	-0.2	-0.4	-0.8	-0.4	-0.1	-0.5	-0.6	-0.0	-0.2	0.4	-1.0	-0.7
Frequency of depressed mood in last 2 weeks	0.1	0.1	0.7	-0.4	-0.2	0.2	-0.3	-0.7	-0.4	-0.2	0.0	-0.4	0.8	-0.3	-0.2
Vitamin and mineral supplements	0.1	0.1	0.7	-0.0	-0.1	-0.3	-0.1	-0.2	-0.0	0.3	-0.6	0.1	-0.8	-0.0	0.3
Relative age voice broke	0.1	0.2	0.9	-0.2	-0.2	0.9	-0.0	-0.7	0.0	-0.5	-0.4	-0.4	0.3	-0.1	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.2	1.6	0.1	0.1	-0.3	0.7	0.4	0.1	-0.2	-0.9	0.3	1.3	-0.1	-0.3
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.5	0.2	0.2	-0.4	-0.1	0.3	-0.1	0.1	0.1	0.7	-0.6	0.2	0.1
Qualifications: CSEs or equivalent	0.1	0.1	0.8	0.2	0.2	0.4	0.3	0.9	0.3	0.0	0.3	0.6	0.2	-0.4	-0.1
High blood pressure (mother)	0.1	0.2	0.8	0.2	0.1	0.1	-0.6	0.3	0.6	0.2	0.7	-0.1	0.9	0.2	0.1
Alcohol usually taken with meals	0.1	0.2	0.9	-0.6	-0.7	0.0	-0.3	-0.3	-0.6	-0.9	-0.6	-0.4	0.1	-0.4	-0.6
Weight	0.1	0.3	1.3	0.2	0.2	-0.9	-1.1	-0.6	-0.0	0.6	-1.1	-0.0	-0.3	-0.1	0.8
Hip circumference	0.1	0.6	1.5	0.9	1.0	1.1	0.1	0.6	1.2	0.7	-0.5	0.8	0.1	1.1	1.2
Worrier / anxious feelings	0.1	0.1	0.5	0.3	0.2	-0.7	-0.3	-0.3	0.3	0.7	-0.0	0.0	0.3	0.2	0.4
Noisy workplace	0.1	0.1	0.5	0.3	0.5	0.3	0.1	0.7	0.3	-0.3	-0.1	0.4	0.3	0.4	-0.0
Prospective memory result	0.1	0.1	0.7	0.3	0.3	0.2	0.4	-0.5	0.3	0.5	0.2	-0.3	0.1	0.3	0.8
Tense / ‘highly strung’	0.1	0.2	0.7	0.3	0.5	0.7	-0.1	-0.1	0.5	0.3	0.1	0.2	0.8	-0.2	0.6
Blood clot in the leg (DVT)	0.1	0.2	1.0	0.5	0.3	-0.4	-1.0	0.6	0.1	0.3	0.3	0.6	-0.0	-0.6	0.1
Worry too long after embarrassment	0.1	0.1	0.4	-0.1	-0.1	0.6	0.2	-0.0	0.1	-0.3	-0.6	0.0	-0.4	0.1	-0.3
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.5	0.4	0.5	-0.4	0.1	0.7	0.5	0.5	-0.4	0.0	0.3	0.0	0.3
Mouth/teeth dental problems: Loose teeth	0.1	0.2	1.2	0.2	0.2	0.3	-0.4	0.3	0.3	0.1	0.6	0.5	-1.1	0.1	0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.1	0.1	0.5	-0.1	-0.2	-0.0	-0.7	-0.1	-0.1	-0.3	-0.7	-0.3	-0.2	0.0	-0.4
Illnesses of father: Heart disease	0.1	0.2	1.0	0.4	0.3	-0.2	0.1	-0.4	0.4	1.0	0.4	-0.1	-0.1	0.6	0.7
Handedness (chirality/laterality): Left-handed	0.1	0.2	0.9	0.3	0.4	0.0	0.3	0.9	0.2	-0.0	0.3	0.5	1.0	0.1	0.1
Mood swings	0.1	0.2	1.2	0.1	0.1	-0.7	-0.7	-0.1	-0.1	0.2	-0.6	0.3	1.1	0.2	0.3
Loneliness, isolation	0.1	0.1	0.5	0.3	0.3	-0.3	-0.2	-0.2	0.2	0.3	-0.1	0.1	0.7	0.4	0.3
Medication: Aspirin	0.1	0.2	0.6	0.3	0.4	0.2	0.4	-0.4	0.1	0.8	0.5	0.1	-0.6	0.1	0.7
Smoking status: Current	0.1	0.2	0.8	-0.0	-0.1	0.4	-0.9	-0.8	0.2	0.6	-0.6	-0.0	-0.6	0.1	0.6
Ever smoked	0.1	0.2	0.8	0.3	0.3	-0.6	0.4	0.7	0.1	0.2	-0.4	0.9	0.0	0.1	0.3
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.5	0.1	-0.0	-0.7	-0.4	0.0	0.1	0.4	-0.3	0.5	-0.3	0.1	0.7
Depression (Nagel 2018)	0.0	0.0	0.1	-0.2	-0.1	0.4	0.1	-0.3	-0.2	-0.1	0.3	0.1	0.1	-0.1	-0.1
Worry (Nagel 2018)	0.0	0.1	0.2	0.4	0.4	0.0	-0.4	0.0	0.4	0.4	0.0	0.2	0.4	0.3	0.3
Blood White Count	0.0	0.3	0.8	-0.3	-0.4	0.8	-0.8	-0.3	-0.4	-0.6	0.9	-0.3	-0.6	-0.0	-0.6
Hair Pigment	0.0	0.1	0.5	-0.3	-0.2	0.2	0.4	0.2	-0.0	0.1	0.3	0.0	-0.0	-0.7	-0.2
Tanning	0.0	0.3	1.6	0.2	-0.0	0.1	0.2	0.9	0.1	-0.6	0.1	0.8	1.3	0.1	-0.4
Townsend deprivation index at recruitment	0.0	0.1	0.3	-0.1	-0.2	-0.1	-0.5	0.3	-0.3	-0.3	0.4	0.1	0.1	-0.2	-0.1
Medication: Aspirin	0.0	0.1	0.3	0.1	0.1	-0.2	0.3	-0.4	-0.2	0.5	0.1	0.0	-0.2	-0.1	0.4
Ever depressed for a whole week	0.0	0.1	0.2	-0.1	-0.0	0.1	0.4	-0.5	-0.3	0.1	-0.3	-0.1	-0.0	-0.4	-0.1

Hub : Genes

MYO9A

Models

Trait associations