Best TWAS P=2.4e-15 · Best GWAS P=9.75e-16 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | KIAA1614 | 0.19 | 0.17 | lasso | 7 | 0.18 | 2.9e-21 | 8.0 | -7.9 | 2.4e-15 | -0.97 | 0 | 1.00 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | KIAA1614 | 0.11 | 0.01 | blup | 59 | 0.06 | 7.5e-07 | 3.8 | -5.2 | 2.3e-07 | -0.61 | 0 | 0.97 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | KIAA1614 | 0.25 | 0.08 | lasso | 3 | 0.07 | 3.6e-07 | 8.0 | -7.8 | 5.7e-15 | -0.94 | 0 | 1.00 | FALSE |