[Hub]/) : Traits : Sitting height :

chr17:36,211,659-37,674,683

Best TWAS P=2.51e-22 · Best GWAS P=2.45e-21 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PIP4K2B 0.15 0.07 lasso 5 0.07 2.2e-06 -9.5 -9.1 6.0e-20 0.95 0.00 1.00 FALSE
2 GTEx Artery Aorta PSMB3 0.23 0.17 enet 26 0.22 2.1e-12 -9.5 -7.5 8.6e-14 0.84 0.00 1.00 FALSE
3 GTEx Artery Aorta PIP4K2B 0.31 0.03 enet 42 0.10 2.6e-06 -1.2 -5.9 3.4e-09 0.46 0.04 0.94 FALSE
4 GTEx Artery Tibial PSMB3 0.10 0.02 enet 12 0.03 1.2e-03 -9.5 -7.2 5.0e-13 0.73 0.00 1.00 FALSE
5 GTEx Artery Tibial PIP4K2B 0.37 0.16 enet 49 0.22 2.1e-17 -9.5 -8.8 1.1e-18 0.76 0.00 1.00 FALSE
6 GTEx Pituitary CWC25 0.30 0.00 enet 18 0.07 7.4e-03 -4.9 -5.2 2.3e-07 0.46 0.08 0.24 FALSE
7 GTEx Testis PSMB3 0.30 0.24 lasso 4 0.21 8.9e-10 -9.5 -9.7 2.5e-22 1.00 0.00 1.00 TRUE
8 METSIM Adipose PIP4K2B 0.06 0.01 blup 360 0.02 7.0e-04 -2.3 -5.5 4.1e-08 0.50 0.01 0.98 FALSE
9 METSIM Adipose PSMB3 0.04 0.02 lasso 5 0.01 2.3e-03 -6.9 -6.7 2.2e-11 0.51 0.14 0.31 FALSE
10 NTR Blood PIP4K2B 0.02 0.01 lasso 3 0.01 6.4e-04 -9.5 9.2 4.6e-20 -0.97 0.00 1.00 FALSE
11 YFS Blood PSMB3 0.14 0.11 enet 31 0.16 7.2e-49 -9.0 -5.6 2.1e-08 0.81 0.00 1.00 FALSE
12 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PIP4K2B 0.04 0.01 blup 56 0.03 6.3e-04 -9.0 -6.8 8.0e-12 0.83 0.00 0.92 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PIP4K2B 0.07 0.01 enet 12 0.02 4.3e-03 -4.9 -6.4 1.8e-10 0.52 0.03 0.28 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PSMB3 0.14 0.05 blup 42 0.05 8.9e-07 -9.0 -6.8 1.4e-11 0.70 0.00 1.00 FALSE
15 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PSMB3 0.12 0.02 enet 14 0.05 1.3e-03 -6.9 -7.1 1.3e-12 0.63 0.01 0.74 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma PIP4K2B 0.05 0.04 blup 56 0.05 5.3e-06 -6.9 -9.1 6.1e-20 0.86 0.00 0.99 FALSE
17 The Cancer Genome Atlas Prostate Adenocarcinoma PSMB3 0.11 0.07 blup 42 0.07 9.4e-08 -9.5 -5.8 5.2e-09 0.77 0.00 1.00 FALSE
18 The Cancer Genome Atlas Testicular Germ Cell Tumors PSMB3 0.12 0.09 lasso 3 0.06 3.0e-03 -9.0 -9.3 1.0e-20 0.97 0.00 0.93 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma PSMB3 0.05 0.06 lasso 1 0.05 2.4e-05 -9.5 -9.5 2.5e-21 1.00 0.00 1.00 FALSE