[Hub]/) : Traits : Sitting height : ← →

chr19:1,400,866-6,033,976

Best TWAS P=2.19e-22 · Best GWAS P=1.62e-27 conditioned to 0.00273

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum NFIC 0.20 0.00 lasso 5 0.02 2.2e-02 5.1 -5.4 6.9e-08 -0.04 0.07 0.18 TRUE
2 GTEx Artery Tibial DOT1L 0.09 0.06 lasso 5 0.05 7.3e-05 9.4 8.6 8.6e-18 0.78 0.32 0.59 FALSE
3 GTEx Breast Mammary Tissue (Male) CTB-50L17.5 0.26 -0.01 enet 23 0.03 7.9e-02 3.1 -5.3 9.8e-08 0.06 0.04 0.34 TRUE
4 GTEx Colon Transverse PTPRS 0.17 -0.01 enet 21 0.03 1.9e-02 1.9 -6.4 1.1e-10 -0.01 0.05 0.30 TRUE
5 GTEx Nerve Tibial IZUMO4 0.23 0.07 lasso 6 0.14 1.9e-10 -1.6 -5.6 1.8e-08 -0.65 0.61 0.38 FALSE
6 NTR Blood C19orf35 0.03 0.01 enet 9 0.02 3.7e-07 -2.3 -5.5 4.2e-08 -0.46 0.98 0.01 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma AP3D1 0.01 0.01 blup 52 0.01 5.4e-03 -1.5 6.3 2.8e-10 0.71 0.04 0.36 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DOT1L 0.08 0.12 enet 8 0.10 2.5e-11 9.4 9.7 2.2e-22 0.84 0.87 0.13 TRUE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma JSRP1 0.07 0.04 blup 33 0.03 7.8e-03 -2.1 5.2 1.6e-07 0.44 0.01 0.10 FALSE
10 The Cancer Genome Atlas Liver Hepatocellular Carcinoma DOT1L 0.09 0.08 blup 60 0.07 4.1e-04 -8.1 7.9 2.8e-15 0.68 0.26 0.44 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma JSRP1 0.03 0.00 blup 33 0.02 2.1e-03 -2.6 -6.8 8.4e-12 -0.52 0.01 0.27 TRUE
12 The Cancer Genome Atlas Testicular Germ Cell Tumors DOT1L 0.40 -0.01 enet 20 0.03 3.6e-02 -4.0 6.4 1.9e-10 0.50 0.01 0.24 FALSE