Hub : Genes

ZFP28

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.2270 0.0540 3.7e-07 0.066 NA 0.089 NA 0.073 4.6e-06 NA 1.0e-07 NA 1.3e-06
2 GTEx Artery Aorta 0.2220 0.0720 4.3e-04 0.134 NA 0.072 NA 0.116 7.5e-08 NA 8.7e-05 NA 6.4e-07
3 GTEx Brain Caudate basal ganglia 0.5900 0.1170 3.3e-04 -0.010 NA 0.009 NA 0.063 9.7e-01 NA 1.7e-01 NA 6.9e-03
4 GTEx Brain Cortex 0.2440 0.0930 5.2e-03 0.106 NA 0.001 NA 0.113 7.7e-04 NA 3.1e-01 NA 5.0e-04
5 GTEx Cells Transformed fibroblasts 0.2140 0.0500 8.0e-07 0.130 NA 0.131 NA 0.132 5.9e-10 NA 5.3e-10 NA 4.6e-10
6 GTEx Colon Transverse 0.2230 0.0680 9.6e-04 0.087 NA 0.039 NA 0.067 6.3e-05 NA 5.8e-03 NA 4.3e-04
7 GTEx Esophagus Mucosa 0.1290 0.0460 8.2e-04 0.086 NA 0.037 NA 0.062 2.4e-06 NA 1.7e-03 NA 5.9e-05
8 GTEx Lung 0.0835 0.0346 9.9e-03 0.016 NA 0.000 NA 0.013 2.0e-02 NA 3.5e-01 NA 3.1e-02
9 GTEx Muscle Skeletal 0.0678 0.0268 4.2e-03 0.023 NA 0.049 NA -0.002 2.4e-03 NA 1.3e-05 NA 6.9e-01
10 GTEx Nerve Tibial 0.1887 0.0480 4.9e-06 0.140 NA 0.144 NA 0.026 4.2e-10 NA 2.2e-10 NA 5.3e-03
11 GTEx Pancreas 0.2060 0.0660 7.0e-04 0.036 NA -0.001 NA 0.015 1.2e-02 NA 3.4e-01 NA 7.7e-02
12 GTEx Skin Not Sun Exposed Suprapubic 0.2400 0.0520 2.4e-07 0.159 NA 0.154 NA 0.177 4.5e-09 NA 8.7e-09 NA 5.5e-10
13 GTEx Skin Sun Exposed Lower leg 0.1900 0.0400 1.5e-08 0.127 NA 0.158 NA 0.166 1.1e-10 NA 4.4e-13 NA 1.1e-13
14 GTEx Testis 0.2470 0.0700 2.4e-04 0.087 NA 0.081 NA 0.066 1.1e-04 NA 1.9e-04 NA 6.9e-04
15 GTEx Thyroid 0.1390 0.0410 2.3e-04 0.048 NA 0.100 NA 0.100 1.4e-04 NA 4.4e-08 NA 4.6e-08
16 GTEx Whole Blood 0.1130 0.0340 6.0e-05 0.099 NA 0.086 NA 0.084 2.1e-09 NA 2.5e-08 NA 3.9e-08
17 METSIM Adipose 0.1314 0.0284 6.7e-14 0.094 0.109 0.111 0.115 0.113 6.5e-14 6.1e-16 3.1e-16 7.3e-17 1.3e-16
18 NTR Blood 0.0561 0.0124 8.3e-12 0.052 0.045 0.059 0.054 0.060 3.2e-16 2.0e-14 2.4e-18 8.0e-17 1.3e-18
19 YFS Blood 0.0308 0.0086 6.7e-07 0.032 0.023 0.020 0.025 0.026 8.8e-11 3.0e-08 2.5e-07 9.2e-09 6.5e-09
20 TCGA Breast Invasive Carcinoma 0.0250 0.0120 2.4e-04 0.011 0.013 0.018 NA 0.017 2.4e-03 8.6e-04 1.2e-04 NA 1.4e-04
21 TCGA Kidney Renal Clear Cell Carcinoma 0.0260 0.0147 6.2e-03 0.022 0.019 0.023 NA 0.018 1.3e-03 2.8e-03 1.1e-03 NA 3.4e-03
22 TCGA Brain Lower Grade Glioma 0.0541 0.0272 5.8e-04 0.016 0.031 0.011 NA 0.015 5.9e-03 1.5e-04 1.6e-02 NA 6.4e-03
23 TCGA Prostate Adenocarcinoma 0.0761 0.0331 1.2e-04 0.062 0.023 0.049 NA 0.052 4.7e-07 1.5e-03 6.4e-06 NA 3.9e-06
24 TCGA Thyroid Carcinoma 0.0470 0.0270 6.4e-03 0.037 0.030 0.028 NA 0.026 1.4e-04 6.0e-04 8.3e-04 NA 1.4e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24
Bipolar Disorder (2018) 0.5 0.9 3.2 -0.9 -0.1 0.6 -0.3 -0.8 -1.2 -1.7 -0.2 -0.1 -0.6 -1.6 -1.3 -1.2 -0.8 -0.8 -0.9 -0.7 -0.6 -1.0 0.6 -1.8 -0.8 -0.5 0.5
Bipolar Disorder or Schizophrenia 2.6 6.3 19.1 -3.4 0.1 2.7 -0.0 -2.9 -2.3 -3.3 -0.3 -2.2 -0.9 -2.5 -3.5 -3.4 -1.7 -0.5 -3.2 -2.8 -2.7 -3.3 -2.0 -4.4 -3.0 -0.9 0.7
Depressed Affect (Nagel 2018) 0.9 1.9 11.2 0.5 1.0 -2.0 1.2 0.4 0.9 1.7 1.0 0.6 0.6 0.9 2.0 1.9 1.4 -0.4 1.3 1.1 1.1 1.9 1.5 0.1 0.0 -1.6 -3.3
Depression (Nagel 2018) 0.5 0.8 4.6 -0.0 0.7 -1.6 0.8 -0.6 1.2 0.4 0.7 0.2 0.5 0.9 1.1 0.8 0.9 0.1 0.7 0.5 -0.2 1.2 0.6 -0.4 -1.0 -0.9 -2.1
Intelligence (Savage-Jansen 2018) 0.4 1.3 4.2 -1.3 -1.7 -0.8 -1.9 0.7 -1.3 -0.7 -1.8 0.5 -2.0 -1.0 -1.1 -0.8 -1.6 -1.9 -0.5 -0.0 0.7 -0.8 0.8 -0.5 0.9 -0.0 0.7
Neuroticism (Nagel 2018) 0.7 1.6 10.6 -0.5 2.0 -0.6 2.1 -0.9 -0.0 0.3 1.9 0.2 1.6 -0.2 0.8 0.5 1.4 0.7 -0.3 -0.4 -0.4 0.7 -0.2 -1.0 -1.8 -1.4 -3.2
Schizophrenia (2018) 3.2 6.7 17.6 -3.7 0.2 3.0 0.2 -3.0 -2.1 -2.9 -0.2 -2.8 -0.7 -2.0 -3.5 -3.4 -1.5 -0.0 -3.4 -3.0 -2.9 -3.4 -3.0 -4.2 -3.2 -0.8 0.5
Schizophrenia vs Biploar Disorder 0.5 0.7 3.0 -0.5 1.3 0.9 1.3 -0.8 0.7 0.1 1.1 -1.0 1.4 0.5 0.1 -0.2 0.8 1.7 -0.7 0.0 -0.8 -0.2 -1.2 -0.2 -0.8 -0.1 0.3
Worry (Nagel 2018) 0.6 1.2 3.6 -1.7 0.5 -0.5 0.6 -1.3 -1.3 -1.2 0.5 -0.5 0.3 -1.2 -0.8 -1.2 -0.6 0.1 -1.6 -1.3 -1.1 -0.8 -0.9 -1.2 -1.9 -0.6 -1.7
Alzheimer’s Disease (in mother) 0.7 0.8 2.3 0.7 1.3 -1.0 1.4 -0.7 1.0 0.3 1.5 0.4 1.5 0.6 0.8 0.6 1.4 1.3 0.8 -0.2 -0.8 0.8 -0.6 0.0 -0.4 -0.2 -0.1
Alzheimer’s Disease (in father) 0.2 0.3 1.1 0.5 -0.7 0.4 -0.4 0.2 -0.3 -0.4 -0.7 0.2 -0.5 0.1 -0.5 -0.5 -1.0 -0.5 0.3 -0.7 0.2 -0.2 1.1 -0.4 0.1 0.4 -0.5
Alzheimer’s Disease (including proxy) 0.2 0.3 0.8 0.8 0.4 -0.3 0.5 -0.8 0.2 -0.4 0.6 -0.0 0.7 0.5 -0.1 -0.4 0.4 0.7 0.5 -0.7 -0.9 0.0 -0.3 -0.7 -0.6 0.0 -0.3
Crohns Disease (2017) 0.8 1.8 4.2 2.0 -0.5 -1.9 -0.4 1.5 1.8 1.2 -0.1 1.3 0.4 1.7 1.7 1.9 1.0 0.4 1.8 1.4 1.7 2.0 0.2 1.8 1.1 0.0 0.1
Irritable Bowel Disease (IBD) 0.7 1.7 4.1 1.7 -0.9 -1.8 -0.8 1.9 1.2 1.0 -0.5 1.3 -0.2 0.8 1.5 1.6 0.1 -0.4 1.4 0.8 1.9 1.5 0.6 2.0 2.0 0.4 0.9
Ulcerative Colitis (UC) 0.7 1.4 5.9 1.0 -1.1 -1.1 -1.0 1.9 0.2 0.7 -0.8 1.5 -0.6 -0.2 0.8 0.9 -0.7 -1.1 0.8 0.1 1.7 0.6 1.0 2.0 2.4 0.9 1.6
Major Depression (MDD) 0.1 0.1 0.8 -0.1 -0.2 -0.7 -0.3 0.3 -0.1 0.1 0.0 0.9 -0.3 0.1 0.0 -0.1 0.4 -0.6 -0.5 0.1 0.5 -0.3 0.6 -0.0 0.6 0.3 -0.0
Reaction Time 1.2 2.3 6.6 -1.3 -0.3 0.4 -0.8 -1.3 -1.9 -2.6 -0.5 -0.7 -0.9 -1.9 -2.2 -2.4 -1.1 -0.7 -2.4 -1.5 -1.5 -2.4 -0.8 -1.7 -0.3 0.4 1.8
Verbal and Numeric Reasoning (VNR) 0.2 0.4 1.2 0.9 -0.6 -0.6 -0.8 0.9 -0.7 0.2 -0.6 -0.1 -0.7 -0.5 0.0 0.4 0.1 -0.8 0.1 0.9 0.8 0.2 1.1 -0.0 0.7 -1.1 0.1
Breast Cancer 0.2 0.6 3.1 0.5 -0.3 -1.1 -0.1 0.8 0.6 0.6 0.1 1.8 0.3 -0.0 0.8 0.7 -0.9 0.2 0.8 -0.5 0.1 0.8 1.0 1.3 0.9 1.0 -0.1
Ovarian Cancer 0.8 1.0 5.3 1.1 0.5 -0.2 0.3 0.6 0.8 1.4 0.3 2.3 0.4 0.8 1.1 0.9 0.9 0.4 1.4 1.6 0.6 1.0 0.5 1.7 0.8 0.5 0.7
Prostate Cancer 0.2 0.3 0.7 0.4 -0.9 -0.6 -0.5 -0.6 0.0 -0.2 -0.7 -0.1 -0.7 0.4 -0.3 -0.3 0.2 -0.6 -0.2 0.2 -0.7 -0.1 -0.8 -0.5 -0.7 -0.6 -0.2
Age at First Birth 1.2 1.8 5.8 -0.7 -2.1 0.5 -2.3 0.2 -1.4 -1.7 -2.4 -0.7 -2.1 -1.0 -1.8 -1.4 -1.7 -1.6 -0.7 -0.5 0.2 -1.3 0.6 -0.9 0.1 1.2 0.8
Bipolar Disorder (2011) 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 -0.2 -0.7 -0.3 0.6 0.7
Body Mass Index (BMI) (2010) 0.4 0.5 3.0 -1.7 -0.8 -0.7 -0.7 0.2 -0.0 -0.5 -1.0 -1.1 -1.1 0.2 -0.6 -0.2 -0.4 -0.8 -0.4 0.1 0.2 -0.3 0.3 -1.0 -0.0 -0.5 -0.9
Coronary Artery Disease (CAD) 1.5 1.8 6.1 -1.2 0.7 2.5 1.0 -1.4 -1.7 -0.8 0.5 -0.8 0.8 -1.7 -1.2 -1.7 -0.4 1.7 -1.5 -1.4 -1.2 -1.4 -1.1 -1.1 -1.3 1.1 1.7
Crohns Disease (2012) 0.1 0.2 1.5 0.5 -0.3 -1.2 -0.6 0.3 0.4 -0.4 -0.5 -0.3 -0.2 0.4 -0.1 0.0 -0.1 -0.0 -0.0 0.0 0.0 0.2 -0.4 -0.0 0.4 0.5 0.6
Mean Putamen Volume 0.3 0.4 1.8 0.3 0.4 0.2 0.6 -1.3 -0.1 0.3 0.4 0.0 0.2 -0.5 0.3 -0.3 0.1 -0.1 0.2 -0.8 -1.3 0.1 -0.8 -0.2 -1.2 -1.1 -0.3
Fasting Glucose 0.3 0.4 1.1 -0.2 -0.8 -0.6 -0.9 -0.7 -0.3 -0.5 -0.8 -0.6 -0.8 -0.2 -0.6 -0.7 -0.7 -0.8 0.1 -0.5 -1.0 -0.4 -0.2 -0.6 -0.0 -0.4 0.4
HbA1C 0.6 0.7 2.3 -0.8 -1.1 0.4 -0.8 0.5 -0.5 -0.7 -1.1 -1.5 -1.2 -0.2 -0.8 -0.4 -1.2 -0.8 -1.4 -0.6 0.3 -0.9 -0.3 -0.4 -0.3 0.7 -0.7
HDL Cholesterol 1.4 2.4 6.6 1.6 -0.7 -0.3 -0.6 2.6 1.8 1.6 -0.3 0.9 0.1 1.8 1.7 2.1 0.5 0.0 2.5 1.9 2.4 1.7 1.6 2.1 1.9 0.5 -0.1
LDL Cholesterol 1.4 2.2 5.3 -1.5 0.7 1.3 0.8 -2.0 -0.6 -1.3 0.5 0.4 0.6 -0.7 -1.6 -2.3 -0.3 1.3 -1.9 -2.3 -2.3 -2.1 -2.0 -1.1 -1.9 1.3 0.5
Lupus 2.5 3.7 8.0 -1.7 -2.6 1.3 -2.3 0.6 -2.6 -1.9 -2.6 -0.8 -2.2 -2.3 -2.6 -2.3 -2.7 -0.9 -2.1 -1.5 0.1 -2.8 -0.3 -1.0 0.9 1.8 2.3
Neuroticism (2016) 0.3 0.4 1.8 -1.4 0.4 -0.1 0.4 -0.4 -1.3 -0.3 0.3 0.0 0.1 -1.3 -0.1 -0.3 0.7 -0.2 -0.3 -0.5 -0.5 -0.4 0.2 -0.7 -0.8 -0.6 -0.9
Primary Biliary Cirrhosis 0.4 0.5 5.3 -0.4 -0.3 0.3 -0.2 -0.7 0.7 -0.3 -0.2 -0.2 -0.6 1.1 -0.3 -0.1 -0.2 -1.0 -0.1 -0.7 -0.4 -0.2 0.4 -0.9 -0.4 -1.0 -2.3
Rheumatoid Arthritis 3.5 4.8 14.1 2.0 -0.5 -3.1 -1.4 3.0 1.6 2.0 -0.6 0.8 -0.6 1.9 2.5 2.8 0.9 -1.6 2.8 3.0 3.3 2.6 2.6 2.7 3.8 0.2 0.3
Schizophrenia (2014) 0.7 1.6 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 -3.1 -2.7 -3.5 -2.8 -0.4 0.6
Triglycerides 1.0 1.6 4.3 -1.9 0.7 0.8 0.4 -1.9 -1.2 -1.4 0.4 -1.2 0.0 -0.8 -1.6 -2.0 -0.4 -0.2 -1.4 -1.7 -1.9 -1.4 -1.4 -2.1 -1.0 -0.5 0.0
Type 2 Diabetes (T2D) (2012) 1.8 2.0 5.7 -1.9 -0.7 0.4 -1.6 -1.0 -1.4 -2.4 -1.0 -1.2 -1.5 -0.8 -2.2 -1.9 -1.3 -1.2 -1.8 -1.4 -1.3 -1.5 -0.8 -2.1 -1.3 0.1 -0.3
Ulcerative Colitis 0.8 1.2 4.0 -1.1 -1.3 -1.3 -1.4 1.3 -0.6 -0.6 -1.3 0.8 -1.5 -0.6 -0.5 -0.2 -1.0 -2.0 -0.2 -0.4 1.0 -0.7 1.0 0.4 1.9 0.6 1.2
Blood Eosinophil Count 0.1 0.7 3.2 -1.8 0.0 -0.5 -0.1 -0.5 -0.2 -1.3 -0.1 -0.6 -0.6 0.0 -0.8 -0.6 -1.3 -1.2 -0.7 -0.9 -0.3 -0.5 -0.1 -1.4 -0.8 -1.5 -0.5
Blood Platelet Count 1.0 11.6 29.5 -3.5 -2.1 1.5 -2.2 -2.0 -4.2 -4.4 -2.3 -1.1 -2.1 -4.7 -4.6 -4.9 -4.4 -0.8 -4.0 -5.4 -3.4 -4.4 -2.5 -2.8 -1.6 2.6 3.6
Blood Red Count 0.3 2.5 7.2 2.5 1.5 0.0 1.8 0.2 0.7 2.2 1.6 1.1 1.6 0.3 2.1 2.0 1.9 1.4 1.2 1.8 0.7 1.5 1.7 0.9 -0.5 -1.6 -2.7
Blood White Count 0.4 3.0 8.8 -1.6 1.1 1.8 1.1 -2.5 -1.1 -1.7 1.1 -1.4 1.0 -1.5 -1.6 -2.1 0.1 1.5 -2.0 -2.2 -2.7 -1.8 -2.3 -1.8 -3.0 0.7 -0.0
Heel T-Score 1.2 9.9 20.6 -3.8 -2.0 1.3 -2.5 -2.3 -3.0 -4.5 -2.3 -2.8 -2.8 -3.6 -4.5 -4.4 -3.7 -2.2 -4.3 -4.3 -2.6 -4.1 -1.5 -4.1 -1.7 0.3 1.7
BMI 0.3 1.5 9.7 -1.1 1.0 0.8 1.1 -1.4 0.1 0.2 1.1 -2.3 0.4 -0.3 0.2 0.2 0.9 -0.1 -0.7 -0.3 -0.8 -0.2 -1.4 -1.2 -2.0 -3.1 -1.7
Height 0.8 15.6 42.8 5.0 0.5 -2.7 0.6 4.3 3.2 5.0 1.2 3.1 1.3 4.0 4.8 5.6 3.5 0.2 5.2 6.5 5.6 4.8 5.2 4.7 4.0 -0.5 -1.9
Waist Hip Ratio (WHR) 1.8 8.0 23.1 -1.4 1.1 2.7 1.4 -4.2 -2.7 -2.9 0.9 -3.1 0.9 -2.6 -2.9 -3.7 0.5 1.9 -3.3 -3.1 -4.3 -3.1 -3.5 -4.1 -4.8 0.3 -1.1
Systolic Blood Pressure 0.6 3.2 6.9 1.4 2.3 -0.0 2.5 -0.5 2.4 2.1 2.5 0.2 2.6 1.9 2.2 1.9 2.3 2.3 1.5 1.1 0.0 2.2 0.4 0.6 -1.3 -1.1 -2.4
Smoking Status 0.7 1.6 6.1 1.6 1.0 -1.5 1.1 0.2 1.3 2.5 1.3 0.1 1.3 1.1 2.0 1.7 1.6 1.0 1.1 1.1 -0.1 1.3 -0.4 1.7 0.3 -0.2 -0.7
Allergy or Eczema 0.3 0.7 3.1 -0.9 -0.2 -1.0 -0.2 -0.6 -1.0 -1.2 -0.5 -0.8 -0.9 -0.3 -1.1 -0.7 0.1 -1.0 -0.6 -0.1 -0.5 -0.8 -0.3 -1.8 -1.0 -1.3 -1.0
Cardiovascular Disease 0.5 1.7 4.9 1.4 0.6 -1.6 0.8 0.4 2.2 1.8 0.9 0.5 0.8 2.0 2.0 1.8 1.2 0.0 1.7 1.4 0.5 1.8 0.3 1.3 0.6 -0.7 -1.6
Hypothyroidism (self reported) 0.3 0.7 1.8 0.9 -0.2 -1.4 -0.3 0.8 0.7 0.4 -0.3 -0.6 -0.5 0.5 0.7 1.1 0.5 -1.1 0.6 1.4 1.1 0.8 1.2 0.1 0.8 -1.1 -1.4
Respiratory disease 0.7 1.6 5.9 -0.8 1.4 0.3 1.0 -2.0 0.1 -1.0 1.2 -2.4 0.4 0.3 -0.6 -0.9 0.6 -0.4 -0.3 -1.0 -1.6 -0.7 -1.6 -2.2 -2.1 -1.7 -1.1
Type 2 Diabetes (T2D) (2018) 0.3 0.6 2.3 -0.3 1.2 0.5 1.4 -0.8 0.4 0.3 1.4 -0.3 1.2 -0.2 0.5 0.4 1.1 1.0 -0.3 0.0 -0.6 0.4 -0.5 -0.6 -0.8 -1.5 -0.8
Lung FEV1/FVC ratio 0.2 1.3 4.4 -0.0 -1.0 0.2 -1.4 1.8 -0.5 0.6 -1.0 1.2 -0.8 -0.6 -0.1 -0.2 -0.7 -0.4 0.3 0.2 1.5 -0.4 2.1 1.6 1.6 2.0 1.7
Lung FVC 0.5 2.6 8.5 -0.7 -2.7 -0.7 -2.7 2.2 -0.8 -0.7 -2.6 0.8 -2.1 -0.7 -0.4 0.3 -1.4 -1.9 0.0 0.2 1.8 -0.1 1.3 1.1 2.9 2.2 1.6
Neuroticism 0.2 0.4 2.2 -0.2 0.1 -1.5 0.0 0.2 -1.3 -0.7 0.1 0.6 0.1 -1.3 -0.4 -0.4 -0.1 0.0 -0.4 -0.3 0.2 -0.2 0.6 -0.7 -0.5 0.4 -1.2
Chronotype (morning person) 1.4 3.2 8.8 1.7 -0.6 -2.2 -0.8 2.5 1.4 2.2 -0.6 -0.7 -0.7 1.7 1.9 2.5 -0.2 -1.1 2.0 3.0 2.9 1.8 2.0 1.9 2.6 -0.7 -0.2
Hair Pigment 0.1 1.6 7.7 0.1 2.1 -0.8 1.2 -1.7 1.3 0.4 1.8 -0.9 0.8 1.9 0.9 0.3 1.5 -0.5 0.6 -0.4 -1.3 0.3 -1.1 -0.6 -1.4 -2.8 -1.6
Tanning 0.4 4.9 16.3 2.5 2.1 1.9 2.1 0.7 2.9 4.0 2.3 1.0 2.6 2.2 3.0 2.6 2.7 2.3 2.5 2.2 0.7 2.8 1.0 2.3 0.2 0.2 -1.1
Hand grip strength (left) 0.4 1.0 3.7 0.6 -0.5 -0.4 -0.8 1.5 0.2 0.7 -0.3 1.3 -0.1 0.8 0.6 1.0 0.2 -0.2 1.3 0.8 1.3 0.6 1.0 1.9 1.6 1.8 0.9
Number of treatments/medications taken 0.4 0.8 2.0 0.5 1.0 -1.4 0.8 0.4 0.7 0.6 1.2 0.2 0.9 0.4 1.3 1.1 1.1 0.0 0.9 1.0 1.2 1.2 0.3 0.3 0.5 -1.1 -0.4
Average weekly spirits intake 0.3 0.4 1.9 -0.4 -0.8 -1.4 -0.8 0.6 -0.8 -0.5 -0.9 -0.4 -0.9 -0.7 -0.4 -0.4 -0.8 -0.9 -0.2 -0.4 0.4 -0.3 0.0 0.1 0.5 0.5 0.1
Sensitivity / hurt feelings 0.7 1.3 3.5 -1.3 0.7 -0.7 0.5 -1.2 -1.2 -1.4 0.6 -0.4 0.6 -1.9 -1.0 -1.2 -0.4 0.5 -1.5 -1.9 -1.4 -0.8 -0.9 -1.7 -1.6 0.2 -1.1
Frequency of depressed mood in last 2 weeks 0.8 1.1 4.5 0.3 1.4 -0.4 1.4 -0.9 1.4 0.3 1.5 0.7 1.3 1.1 1.0 0.7 1.7 0.7 0.4 0.5 -0.7 1.2 -0.2 -0.2 -1.5 -0.4 -2.1
Hearing difficulty/problems: Yes 2.4 3.6 12.4 0.6 2.9 2.1 2.6 -3.1 0.5 0.8 2.8 1.0 2.4 0.3 0.5 -0.6 1.9 2.1 0.2 -0.6 -2.4 0.2 -1.9 -1.0 -3.5 -2.3 -2.1
Relative age of first facial hair 1.3 2.6 6.8 -0.5 -2.5 -1.6 -2.6 1.5 -1.4 -2.0 -2.5 -0.8 -2.3 -0.9 -1.7 -0.9 -2.1 -2.1 -0.6 -0.6 0.9 -0.8 0.5 -0.4 2.0 1.9 1.6
Other serious medical condition/disability diagnosed by doctor 0.4 0.6 1.7 -0.8 0.7 -0.9 0.5 -0.1 1.0 0.7 0.6 0.7 0.4 1.1 0.8 0.8 1.3 0.1 0.6 1.1 0.1 0.6 0.1 0.1 -0.4 -0.8 -1.2
Ever used hormone-replacement therapy (HRT) 0.3 0.4 2.3 -1.1 0.2 -0.5 -0.3 -0.3 -1.3 -0.6 0.0 0.1 -0.3 -1.5 -0.5 -0.6 0.0 -0.7 -0.8 -0.2 -0.3 -0.7 0.3 -0.8 0.4 -0.4 0.1
Ever had hysterectomy (womb removed) 0.2 0.3 0.9 -0.5 0.7 0.3 0.7 -1.0 -0.0 -0.4 0.7 0.0 0.5 -0.0 -0.1 -0.5 0.9 0.2 -0.6 -0.2 -0.8 -0.2 -0.6 -0.2 -0.6 0.3 -0.4
Systolic blood pressure, automated reading 0.8 2.3 4.6 1.1 1.9 -0.6 1.8 0.1 1.8 1.5 2.1 -0.5 1.8 1.6 1.9 1.9 2.1 1.0 1.3 1.5 0.8 2.0 1.0 0.5 -0.6 -1.8 -2.0
Eye problems/disorders: Diabetes related eye disease 0.5 0.6 1.4 0.8 0.3 -0.7 0.3 0.9 0.9 1.1 0.0 -0.4 0.1 1.1 0.9 1.0 -0.3 -0.0 0.8 1.1 1.2 1.0 1.1 0.3 0.3 -0.7 -0.6
Angina 1.1 1.4 2.9 1.7 1.1 -0.2 1.1 1.2 1.2 1.6 0.7 1.7 0.9 1.4 1.6 1.4 1.5 0.6 1.3 1.0 1.1 1.5 0.9 1.3 0.9 -0.1 -0.8
Medication for hormone replacement therapy 0.7 0.8 4.4 -0.7 0.0 -0.7 0.2 -0.9 -1.1 -1.0 -0.1 -2.1 -0.1 -1.1 -1.0 -0.9 -0.3 0.1 -1.0 -1.2 -0.8 -1.0 -0.9 -1.5 -0.8 -0.7 -0.2
Vitamin and mineral supplements 0.5 0.6 3.2 1.0 0.3 1.1 0.7 -0.2 0.9 0.3 0.4 0.9 1.1 0.9 0.3 0.2 0.8 1.8 0.6 0.1 -0.2 0.3 -0.6 0.7 -0.1 1.2 1.4
Supplements: Zinc 0.5 0.5 1.5 -0.7 -1.1 -0.6 -1.0 1.1 -0.4 0.1 -0.9 0.4 -1.0 -0.2 -0.1 0.1 -1.2 -1.1 -0.5 0.4 0.9 -0.1 0.9 0.4 1.2 0.4 0.0
Medication: Co-codamol 0.5 0.5 1.6 -0.8 0.9 0.3 1.0 -1.1 -0.5 0.2 0.9 0.0 0.5 -0.2 0.2 -0.4 0.3 0.2 -1.1 -1.0 -0.9 -0.5 -1.3 -0.3 -0.9 -1.2 -0.6
Medication: Metformin 0.5 0.7 1.7 -1.1 1.0 0.8 1.1 -1.1 -0.1 -0.4 1.0 -0.2 0.8 -0.1 -0.2 -0.5 0.7 0.7 -0.8 -1.3 -1.1 -0.3 -1.1 -1.0 -1.1 -1.3 0.0
Diabetes (father) 0.8 0.9 3.7 -1.1 -0.0 0.8 0.1 0.0 -1.6 -1.2 0.0 1.1 0.4 -1.6 -1.1 -1.0 -0.7 1.3 -0.8 -0.9 -0.4 -0.9 0.2 -0.7 -0.3 1.2 1.9
Diabetes (mother) 1.9 2.4 5.6 -0.4 2.3 1.7 2.2 -2.4 0.5 0.3 2.2 -1.9 1.9 0.1 0.3 -0.3 1.3 1.6 -1.0 -0.9 -2.2 0.0 -2.2 -1.3 -2.1 -2.1 -0.8
Severe depression (siblings) 0.3 0.4 1.5 -0.6 -0.7 0.0 -0.5 0.4 -0.1 0.1 -0.7 -0.5 -0.9 0.1 0.3 0.4 1.0 -1.2 0.2 0.7 0.8 0.3 0.8 0.2 0.8 -0.0 -1.0
Pack years adult smoking proportion 1.5 2.3 8.9 0.8 0.6 -0.4 0.9 0.3 2.5 2.1 0.8 -0.1 0.5 3.0 2.0 1.9 1.5 -0.6 2.3 1.9 0.6 2.0 0.1 1.1 0.8 -1.3 -2.1
Impedance of leg (right) 0.1 0.6 1.9 -0.9 -0.1 0.2 -0.3 -0.5 -1.2 -0.9 -0.1 1.4 0.0 -1.1 -0.6 -1.0 -1.0 0.4 -0.5 -1.2 -0.9 -0.4 0.0 -0.4 -0.4 0.8 0.9
Leg fat-free mass (left) 1.2 6.3 16.0 2.8 0.3 -1.0 0.7 2.5 2.8 3.5 0.7 0.4 0.6 3.0 3.3 4.0 2.7 -0.2 3.1 4.0 3.2 3.0 2.0 2.8 2.0 -1.6 -2.5
Trunk fat percentage 0.3 1.4 8.8 0.5 0.6 -1.3 0.6 -0.6 0.1 0.8 0.7 -1.8 0.0 0.4 0.9 1.0 1.3 -0.8 0.6 1.2 0.2 0.8 0.1 -0.9 -1.0 -3.0 -2.8
Hand grip strength (right) 0.6 1.7 4.5 1.6 -0.3 -1.1 -0.6 2.0 0.9 1.1 -0.2 1.1 0.1 1.3 1.1 1.6 0.4 -0.2 1.7 1.6 2.0 1.3 1.4 2.0 2.1 1.7 0.4
Townsend deprivation index at recruitment 0.4 0.5 2.3 -0.6 0.5 1.3 0.5 -0.5 -1.0 -0.4 0.5 1.4 0.5 -1.5 -0.5 -0.7 0.3 0.5 -0.4 -0.2 -0.8 -0.5 -0.7 -0.3 -0.4 0.5 0.9
Current tobacco smoking 0.7 1.1 3.8 1.5 0.9 -0.7 0.9 -0.2 1.4 1.4 1.1 0.8 0.9 2.0 1.3 1.2 1.8 0.5 0.7 1.1 -0.6 1.0 -0.2 1.0 -0.3 -0.2 -1.1
Average weekly fortified wine intake 1.1 1.3 3.8 -0.9 -1.2 -0.3 -1.6 0.9 -1.3 -1.2 -1.4 1.5 -1.6 -0.5 -1.1 -0.7 -1.6 -1.7 -0.9 0.2 1.0 -0.9 2.0 -0.4 0.4 -0.5 -0.2
Maternal smoking around birth 0.6 0.9 2.0 1.1 0.8 -0.5 0.8 0.9 0.6 1.3 1.0 1.2 0.9 0.7 1.2 1.1 0.3 0.1 1.4 0.8 0.7 0.9 1.1 1.2 1.0 0.5 -0.6
Fed-up feelings 1.6 2.9 15.4 1.3 1.4 -2.3 1.4 -0.3 1.4 2.2 1.6 0.5 0.9 1.3 2.6 2.2 1.8 -0.6 1.5 1.6 0.6 2.1 0.2 0.4 -0.7 -2.1 -3.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.6 0.9 3.2 0.7 0.5 -1.1 0.7 -0.1 1.2 0.6 0.8 1.1 0.7 1.1 1.2 1.0 1.4 0.2 1.0 1.0 0.1 1.2 1.0 0.3 -0.3 -0.2 -1.8
Relative age voice broke 1.9 2.9 7.2 -2.1 -2.5 -0.2 -2.4 0.4 -1.8 -2.1 -2.7 -1.6 -2.4 -1.5 -2.1 -1.4 -2.5 -1.6 -1.9 -1.1 -0.0 -1.4 -0.4 -1.4 0.5 1.1 1.1
Taking other prescription medications 0.7 1.0 6.9 -0.3 0.6 -2.5 0.3 -0.6 0.4 -0.3 0.5 0.2 -0.2 0.3 0.3 0.3 0.5 -1.1 0.1 0.3 -0.0 0.4 0.7 -0.9 -0.8 -2.6 -2.3
Age when periods started (menarche) 0.2 0.5 2.2 -1.2 0.9 1.5 1.0 -0.8 0.1 0.5 1.0 0.5 0.8 -0.3 0.1 -0.2 0.2 0.7 -0.5 -1.3 -0.8 -0.2 -0.3 -0.1 -0.8 -0.4 0.5
Bilateral oophorectomy (both ovaries removed) 0.7 0.9 4.3 -1.1 0.8 1.0 0.8 -1.6 -0.5 -0.3 0.8 -1.0 0.5 -0.7 -0.4 -0.7 0.5 0.3 -1.0 -0.5 -1.6 -0.9 -2.1 -0.6 -0.9 -0.9 0.2
Heel bone mineral density (BMD) T-score, automated (left) 1.8 4.1 9.5 -1.7 -3.0 0.8 -2.7 -0.1 -1.8 -2.7 -3.0 -1.9 -3.1 -1.4 -2.7 -2.2 -2.5 -2.6 -1.6 -2.2 -0.4 -2.3 -0.0 -1.9 0.0 0.7 1.1
Tinnitus: Yes, but not now, but have in the past 1.9 2.0 5.2 -2.3 -0.5 0.3 -0.2 -1.6 -1.7 -1.4 -0.5 -1.7 -1.3 -1.3 -1.9 -2.2 -1.3 -1.4 -1.7 -1.5 -1.2 -2.1 -0.2 -2.0 -1.4 -0.5 -0.5
Qualifications: CSEs or equivalent 0.3 0.4 2.1 -0.8 0.5 -0.4 0.5 -0.4 0.1 -0.5 0.4 -0.0 0.7 -0.2 -0.4 -0.6 -0.6 1.0 -0.1 -0.8 -0.6 -0.2 -1.1 -0.1 -0.4 1.1 1.4
Serious illness, injury or assault to yourself 0.7 0.8 2.0 -1.3 0.3 0.8 -0.1 -1.4 -0.0 -0.9 0.2 -0.6 0.0 0.1 -1.0 -1.3 0.1 0.2 -1.0 -1.3 -1.3 -0.9 -1.4 -1.4 -1.4 0.2 -0.2
High blood pressure 1.6 4.4 11.7 2.5 1.6 -0.4 2.0 0.8 2.8 2.7 1.8 0.6 2.1 2.6 2.9 2.7 3.4 1.7 2.8 2.4 1.1 2.8 0.6 2.0 0.2 -1.0 -1.8
Hayfever, allergic rhinitis or eczema 0.4 0.9 3.9 -0.6 0.3 0.1 0.4 -1.2 -1.1 -1.0 0.1 -1.0 -0.3 -0.9 -1.1 -1.1 -0.3 -0.2 -1.1 -0.6 -0.8 -1.0 -0.9 -2.0 -1.7 -1.4 -0.5
Multivitamins +/- minerals 1.1 1.4 3.7 -0.1 -1.4 -1.4 -1.3 1.9 -1.3 0.1 -1.1 0.1 -1.3 -1.4 0.0 0.4 -1.4 -1.7 -0.1 0.7 1.8 -0.1 1.8 0.7 1.9 0.4 -0.6
Stomach or abdominal pain in last month 0.8 1.0 4.1 1.3 1.0 -2.0 1.0 0.7 0.6 0.5 1.0 0.3 1.2 0.6 0.9 1.3 1.7 0.8 0.9 1.2 0.8 1.3 0.7 0.7 0.3 -0.4 -0.2
Supplements: Glucosamine 0.6 0.8 3.4 1.2 -0.7 -0.1 -0.8 1.7 -0.4 0.3 -0.6 0.1 -0.5 -0.3 0.4 0.7 -0.5 -0.5 0.6 1.2 1.8 0.3 1.4 1.0 1.4 1.1 0.5
Diverticular disease/diverticulitis (self-reported) 2.2 2.6 6.1 1.2 0.7 -0.6 0.8 1.6 1.9 2.0 0.9 2.5 0.9 2.1 1.9 2.3 2.0 0.4 1.9 2.0 1.8 1.7 1.9 1.8 1.2 -0.2 -1.7
Medication: Atenolol 0.2 0.2 2.0 0.1 0.1 -1.4 -0.1 0.2 0.4 0.3 -0.0 0.2 -0.4 0.1 0.3 0.4 0.0 -1.0 -0.3 0.4 0.4 0.3 -0.1 0.3 0.2 -0.4 -0.5
Medication: Levothyroxine sodium 1.1 1.8 7.0 0.8 0.4 -2.7 -0.2 1.6 1.5 0.9 0.1 -0.3 -0.0 1.1 1.4 2.1 0.7 -0.7 1.7 2.3 1.8 1.8 1.5 0.8 1.2 -1.2 -1.5
Sitting height 2.3 16.6 34.8 4.7 -0.4 -2.6 -0.2 5.5 3.9 4.6 -0.1 3.4 0.7 4.6 4.7 5.7 2.5 0.2 5.3 5.9 5.9 4.8 5.2 5.5 5.2 1.0 -0.6
Chronic bronchitis/emphysema (father) 0.6 0.7 5.9 -0.5 -0.4 -0.2 0.3 -1.0 0.0 -0.4 -0.0 -2.4 0.1 -0.1 -0.5 -0.8 -0.2 0.4 -0.7 -1.2 -1.4 -0.5 -1.5 -1.0 -0.8 -0.1 0.0
High blood pressure (mother) 0.4 0.6 2.3 1.5 0.6 -0.6 0.7 -0.0 1.1 0.6 0.8 0.1 0.7 1.4 0.9 0.8 0.6 0.3 0.9 0.5 0.1 1.0 0.9 0.2 -0.0 -0.4 -1.3
Body mass index (BMI) 0.2 1.0 6.1 0.4 0.3 -0.9 0.6 -0.1 0.6 0.7 0.5 -1.8 0.0 0.8 0.8 1.1 1.4 -0.5 0.5 1.2 0.4 0.5 -0.3 -0.4 -0.7 -2.5 -2.3
Impedance of leg (left) 0.1 0.7 2.0 -0.9 -0.5 -0.3 -0.8 0.1 -1.4 -1.0 -0.5 1.1 -0.3 -1.0 -0.8 -1.0 -1.3 0.1 -0.5 -0.9 -0.3 -0.6 0.6 -0.4 0.2 1.3 1.4
Leg predicted mass (left) 1.2 6.3 15.8 2.8 0.3 -1.1 0.6 2.5 2.8 3.5 0.6 0.4 0.6 3.0 3.3 4.0 2.7 -0.3 3.2 4.0 3.2 3.1 2.1 2.8 2.0 -1.6 -2.5
Trunk fat mass 0.6 2.5 8.4 1.5 0.6 -1.4 0.7 0.6 1.1 1.9 0.8 -1.2 0.3 1.4 2.0 2.2 2.1 -0.6 1.6 2.4 1.4 1.7 0.9 0.4 0.1 -2.8 -2.9
Waist circumference 0.5 1.7 9.9 -0.1 0.8 -0.2 1.0 -1.6 -0.2 0.1 0.9 -2.7 0.2 0.1 0.0 0.1 1.5 -0.2 -0.4 0.3 -0.9 -0.4 -1.6 -1.8 -2.1 -3.1 -2.4
Number of incorrect matches in round 0.7 1.1 2.9 -1.4 -1.0 0.1 -1.3 0.3 -1.5 -1.6 -0.9 -0.2 -0.7 -1.0 -1.5 -1.4 -1.4 -0.3 -1.2 -0.9 0.4 -1.3 0.2 -0.7 0.4 1.7 0.7
Past tobacco smoking 1.2 2.2 6.5 -1.6 -1.6 1.7 -1.3 -0.4 -1.6 -2.5 -1.6 -0.9 -1.6 -1.2 -2.3 -1.9 -2.0 -0.9 -1.9 -1.2 -0.4 -1.6 0.4 -2.1 -0.8 0.5 0.5
Alcohol usually taken with meals 4.1 6.6 14.4 2.8 2.2 -0.4 2.1 1.1 3.2 3.2 2.5 2.0 2.8 3.1 3.6 3.6 3.3 2.1 3.2 2.9 1.6 3.8 1.6 2.8 0.7 -0.8 -1.6
Nervous feelings 0.7 1.3 4.8 -1.2 1.5 0.8 1.4 -1.5 -0.7 -0.5 1.6 0.4 1.4 -1.1 -0.5 -0.8 0.1 1.3 -1.4 -0.8 -1.3 -0.4 -0.5 -0.9 -2.2 -0.8 -1.3
Frequency of tenseness / restlessness in last 2 weeks 1.0 1.6 4.5 -0.1 1.9 0.7 2.1 -1.7 0.5 0.2 2.1 1.1 2.0 0.3 0.7 0.0 1.6 1.5 -0.2 -0.9 -1.4 0.6 -0.5 -0.4 -1.8 -0.5 -1.9
Hearing difficulty/problems with background noise 3.3 5.3 14.6 -0.2 3.8 1.4 3.6 -3.8 0.5 1.1 3.7 -0.1 3.1 -0.1 0.7 -0.6 2.3 2.3 -0.4 -1.0 -3.2 0.0 -3.0 -1.1 -3.7 -2.4 -2.6
Hair/balding pattern: Pattern 2 0.4 0.5 3.5 -1.1 0.2 1.9 0.4 -0.5 -0.2 -0.6 0.2 0.3 0.4 -0.3 -0.7 -0.4 -0.0 0.7 -0.8 -0.8 -0.7 -0.5 -0.8 -0.4 -0.6 0.7 -0.2
Had menopause 0.3 0.4 1.7 0.5 0.8 -1.3 0.5 0.3 -0.6 -0.3 0.6 1.0 0.6 -0.7 0.3 0.4 1.1 0.3 0.3 0.9 0.2 0.4 0.6 -0.2 -0.2 0.0 -0.2
Had other major operations 0.1 0.1 0.7 0.4 0.4 -0.2 0.4 -0.0 -0.2 0.5 0.5 0.3 0.3 -0.0 0.3 0.1 0.8 -0.0 -0.1 0.3 -0.1 0.2 -0.5 0.1 0.3 -0.4 0.1
Forced vital capacity (FVC) 0.9 3.3 11.3 0.8 -1.0 -0.9 -1.0 2.9 0.9 1.9 -0.8 2.0 -0.4 1.0 1.8 2.4 0.6 -0.6 1.6 2.3 3.1 1.7 2.5 2.8 3.4 1.0 0.8
Heel bone mineral density (BMD) T-score, automated (right) 2.2 5.0 11.4 -1.9 -3.4 1.5 -2.8 0.4 -2.2 -3.1 -3.3 -1.4 -2.9 -1.9 -3.2 -2.6 -3.0 -1.6 -1.7 -2.3 -0.3 -2.5 0.2 -1.9 0.3 2.1 2.1
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 1.9 -0.1 0.9 -0.2 0.6 -1.3 0.6 0.2 0.9 -0.3 0.5 0.4 0.4 0.1 0.5 -0.1 -0.6 -0.2 -1.2 0.5 -0.9 -0.6 -1.3 -1.2 -1.4
Qualifications: None of the above 0.9 1.9 5.0 -0.8 -0.1 1.7 -0.0 -2.0 -1.0 -1.4 -0.2 -2.1 -0.8 -1.1 -1.4 -1.8 -0.8 -1.0 -1.6 -1.8 -1.9 -1.7 -1.7 -2.2 -1.3 -1.0 -0.1
Financial difficulties in last 2 years 2.8 3.8 9.2 2.5 1.1 -1.5 1.6 1.3 2.2 2.9 1.4 1.2 1.4 2.1 3.0 2.8 1.9 0.6 2.2 2.7 1.3 2.6 1.4 2.5 0.9 -1.0 -1.8
Mouth/teeth dental problems 1.0 1.6 5.6 0.7 -1.9 -0.9 -1.3 2.1 1.1 0.1 -1.6 -0.4 -1.0 1.1 0.4 1.1 -0.9 -0.4 1.4 1.5 2.4 1.1 2.0 1.1 1.5 0.7 -0.4
Heart attack 0.6 0.7 1.9 1.2 0.6 0.1 0.6 0.3 1.3 1.1 0.6 0.5 0.5 1.4 1.1 1.0 0.9 0.0 0.8 0.3 0.6 1.2 1.1 0.4 0.3 -1.0 -1.2
Allergy 0.4 0.8 3.9 0.5 -0.3 -0.4 -0.5 1.3 0.4 0.9 -0.2 1.6 0.2 0.0 0.8 0.8 0.1 0.4 0.6 0.4 0.8 0.6 1.0 2.0 1.6 1.5 0.8
Pain all over the body in last month 0.5 0.6 4.2 0.1 0.1 -0.1 -0.1 -0.2 0.7 -0.2 0.1 0.2 -0.4 1.2 0.0 0.3 0.8 -1.3 -0.1 0.7 0.0 0.1 1.3 -1.0 -0.1 -1.1 -2.0
Diabetes (self-reported) 1.2 1.8 5.8 -0.1 2.0 0.6 2.4 -1.1 0.7 0.4 2.2 -0.7 1.8 0.6 0.8 0.7 1.8 1.4 -0.3 0.1 -0.7 0.6 -0.5 -1.1 -1.8 -2.4 -2.1
Hayfever/allergic rhinitis (self-reported) 0.7 0.9 3.1 -0.4 0.7 0.4 0.6 -1.4 -0.6 -1.0 0.7 -1.2 0.1 -0.3 -0.9 -1.0 0.1 -0.3 -1.2 -0.8 -0.8 -0.8 -1.1 -1.6 -1.8 -1.4 -1.4
Medication: Ramipril 3.6 4.7 13.0 1.3 3.5 0.8 3.6 -1.1 2.2 2.4 3.4 -0.8 3.5 1.4 2.2 1.4 3.6 3.2 0.8 0.6 -0.9 1.7 -2.1 0.7 -1.1 -2.2 -0.5
Medication: Simvastatin 0.6 0.9 2.9 -1.3 0.2 1.2 0.2 -1.5 -0.6 -0.4 0.1 -0.3 0.1 -0.6 -0.6 -1.3 -0.5 0.4 -1.6 -1.4 -1.5 -1.1 -1.7 -1.1 -1.0 -0.4 0.3
Fluid intelligence score 0.2 0.4 2.1 0.5 -0.4 -1.4 -0.3 0.8 -0.4 0.4 -0.3 0.3 -0.4 -0.3 0.3 0.6 0.6 -0.4 0.4 1.1 0.7 0.3 0.7 0.1 0.5 -0.6 -0.7
Illnesses of siblings 1.0 1.4 8.1 -1.6 -1.2 2.8 -1.0 0.1 -1.3 -1.6 -1.2 -0.6 -0.8 -1.3 -1.6 -1.1 -1.2 0.2 -1.0 -1.1 -0.6 -1.3 0.2 -0.5 -0.6 1.3 1.0
Neuroticism score 0.4 0.9 4.2 -1.1 1.1 -0.5 0.9 -1.2 -1.0 -0.5 1.1 0.6 0.8 -1.2 -0.3 -0.6 0.3 0.5 -1.0 -0.9 -0.8 -0.3 -0.5 -1.2 -1.7 -0.2 -2.0
Weight 1.2 5.8 14.8 2.7 0.7 -1.9 1.0 1.8 2.5 3.1 1.1 -0.3 0.8 2.9 3.2 3.7 3.0 -0.3 2.9 3.9 2.8 2.9 1.6 1.9 1.2 -2.6 -3.1
Impedance of arm (right) 0.5 2.2 6.7 -1.3 1.2 1.3 1.2 -2.6 -1.6 -1.4 1.0 -0.4 0.8 -1.9 -1.1 -1.8 -0.2 1.0 -1.4 -1.9 -2.4 -1.0 -1.2 -2.2 -2.3 -0.7 -0.2
Arm fat percentage (right) 0.3 1.2 6.9 -0.3 0.4 0.1 0.8 -1.4 -0.5 -0.1 0.5 -2.3 0.0 -0.5 -0.0 -0.0 1.0 -0.3 -0.3 0.1 -0.8 -0.3 -0.9 -1.5 -1.8 -2.6 -2.3
Trunk fat-free mass 2.1 12.3 28.7 3.8 -0.3 -1.5 0.0 4.4 3.6 4.6 0.1 2.4 0.5 4.0 4.4 5.4 3.0 -0.2 4.4 5.3 4.9 4.2 3.8 4.8 4.0 -0.4 -1.7
Hip circumference 0.5 2.0 10.7 0.7 -0.0 -1.6 0.2 0.7 1.2 1.4 0.2 -1.6 -0.5 1.9 1.3 1.9 1.5 -1.4 1.2 2.0 1.4 1.2 0.5 0.1 0.3 -3.3 -2.2
Time employed in main current job 0.4 0.4 2.3 -0.4 -0.3 0.2 0.2 -0.8 -0.8 -0.3 -0.3 -0.6 0.1 -0.9 -0.4 -0.6 -0.3 0.7 -0.4 -1.0 -1.3 -0.3 -1.5 -0.3 -0.8 0.2 0.7
Alcohol intake versus 10 years previously 0.2 0.3 2.7 0.1 0.5 -0.7 0.5 -0.2 0.9 0.5 0.4 0.1 0.1 0.9 0.3 0.4 0.3 -0.7 0.4 -0.5 0.1 0.4 0.3 -0.4 -0.1 -0.5 -1.6
Father’s age at death 0.8 1.1 2.9 -0.8 -1.4 -0.7 -1.5 -0.1 -1.0 -1.7 -1.4 -0.9 -1.4 -1.0 -1.3 -1.0 -1.4 -1.3 -1.2 -1.1 -0.1 -0.8 -0.4 -1.2 0.3 0.7 0.2
Worrier / anxious feelings 0.6 1.2 5.4 -0.3 1.3 0.3 1.4 -1.5 -0.7 -0.8 1.1 0.3 1.0 -0.7 -0.7 -1.0 0.4 0.9 -1.0 -1.1 -1.2 -0.5 -0.8 -1.1 -2.3 -0.4 -2.1
Frequency of tiredness / lethargy in last 2 weeks 1.6 2.6 7.9 0.1 2.4 -2.0 2.6 -1.1 1.4 1.1 2.6 0.7 2.1 1.3 1.5 1.0 2.8 1.2 0.2 0.6 -0.5 1.4 0.2 -0.0 -1.8 -1.7 -2.7
Falls in the last year 1.7 2.3 7.5 -0.6 2.1 0.8 2.0 -2.4 0.1 -0.4 2.2 -1.1 1.4 -0.1 -0.4 -0.8 1.3 0.8 -1.1 -1.1 -2.0 -0.6 -2.2 -2.0 -2.7 -2.0 -1.4
Hair/balding pattern: Pattern 3 0.6 0.9 2.3 1.2 1.3 1.2 1.2 0.0 0.9 0.9 1.1 0.9 1.4 0.7 0.9 0.5 1.5 1.4 1.2 0.7 0.2 1.1 0.6 0.7 -0.5 -0.8 0.4
Number of live births 0.2 0.2 1.1 -0.8 -0.1 0.8 0.2 -0.1 -0.5 -0.5 -0.2 0.2 -0.3 -0.7 -0.5 -0.4 -0.7 -0.3 -1.0 -0.5 -0.3 -0.3 -0.4 -0.5 -0.2 0.3 -0.2
Forced expiratory volume in 1-second (FEV1) 0.9 3.0 10.6 0.5 -1.1 -0.0 -1.1 3.0 0.7 1.5 -1.0 2.0 -0.5 0.6 1.3 2.1 0.5 -0.5 1.3 2.1 3.2 1.3 2.4 2.7 3.3 1.6 1.2
Pulse rate 0.6 1.0 3.2 0.4 -1.0 0.3 -1.1 -0.1 -1.6 -1.2 -1.1 -1.8 -1.2 -1.0 -1.2 -0.8 -1.4 -0.8 -1.2 -0.3 -0.1 -1.1 -0.5 -1.4 -0.1 -0.5 0.6
Happiness 1.3 1.6 6.2 -0.2 1.5 -1.2 1.0 0.4 1.1 1.3 1.4 0.7 0.7 1.4 1.7 1.6 1.2 -0.4 0.9 1.4 0.6 1.6 1.9 0.4 -0.0 -1.9 -2.5
Noisy workplace 2.5 3.1 6.9 -2.2 -1.2 -0.1 -1.6 -1.2 -1.8 -2.1 -1.6 -0.7 -2.1 -1.5 -2.2 -2.5 -2.4 -2.1 -2.1 -2.6 -1.3 -2.5 -1.6 -1.9 -0.3 0.3 1.2
Qualifications: A levels/AS levels or equivalent 0.1 0.2 0.9 -0.1 0.7 -0.9 0.5 -0.3 0.3 0.0 0.8 -0.8 0.6 0.6 0.2 0.2 0.4 0.0 0.4 -0.6 -0.3 0.4 -0.6 0.3 -0.2 0.4 0.3
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.1 2.7 0.6 1.2 -0.8 1.3 0.5 1.0 0.9 1.3 0.2 1.6 0.8 1.2 1.2 1.5 1.5 1.2 0.6 0.8 1.1 -0.0 1.4 0.7 0.9 0.5
Mouth/teeth dental problems: Dentures 0.8 1.3 5.9 -1.0 0.9 -0.4 0.7 -2.1 -0.5 -0.1 1.1 -0.8 0.3 -0.4 -0.3 -0.9 0.5 -0.7 -0.8 -1.4 -2.4 -0.6 -1.8 -1.5 -1.6 -1.6 -1.0
Asthma 1.0 1.9 7.8 -0.7 0.8 1.3 0.7 -2.0 -0.4 -1.1 0.6 -2.1 -0.0 -0.1 -1.1 -1.4 0.2 -0.2 -0.9 -1.1 -1.7 -1.1 -1.4 -2.8 -2.6 -2.1 -1.4
Medication: Ibuprofen (e.g. Nurofen) 0.2 0.2 1.0 0.6 -0.6 0.1 -0.6 -0.6 -0.5 -0.4 -0.5 -0.4 -0.5 -0.0 -0.2 -0.1 -0.3 -0.6 0.3 0.5 -0.3 0.3 -0.4 -1.0 -0.5 -0.7 -0.7
Medication: Cholesterol lowering 0.3 0.4 1.5 -1.0 0.6 0.3 0.8 -1.2 0.5 0.3 0.7 -0.5 0.5 0.3 0.1 -0.5 -0.1 0.4 -0.2 -0.8 -1.2 -0.3 -0.7 -0.7 -0.8 -0.6 -0.2
Depression (self-reported) 1.7 2.0 6.2 -2.3 -1.4 -1.2 -1.8 -0.5 -1.1 -2.5 -1.5 -0.0 -1.5 -1.3 -1.9 -1.8 -1.7 -1.3 -1.6 -1.1 -0.8 -1.5 0.4 -1.7 -0.5 1.2 0.5
Medication: Lansoprazole 0.5 0.6 1.8 0.4 1.2 -0.3 1.2 -0.8 0.2 0.4 1.1 -0.5 0.9 -0.4 0.5 0.2 1.3 0.5 -0.1 -0.0 -0.5 0.2 -1.2 -0.2 -0.9 -0.9 -1.1
Prospective memory result 0.3 0.4 1.6 -0.1 -0.4 -0.9 -0.8 0.2 -0.5 -0.3 -0.5 -0.9 -0.8 -0.4 -0.1 -0.2 -1.1 -1.3 -0.0 -0.2 -0.1 -0.3 0.2 -0.1 0.9 -0.5 0.7
Lung cancer (father) 0.5 0.5 2.6 0.1 0.7 -0.9 0.4 -1.4 0.6 -0.3 0.5 0.0 0.2 0.6 0.1 -0.3 -0.4 -0.3 -0.2 -0.6 -1.3 0.0 -0.5 -0.8 -1.1 -1.1 -1.6
Illnesses of mother 2.0 2.5 6.1 -2.5 -1.0 1.1 -1.0 -1.6 -1.5 -1.9 -1.2 -1.2 -1.4 -1.2 -2.3 -2.2 -1.0 -0.8 -1.8 -1.4 -1.7 -2.4 -1.8 -2.2 -1.6 -0.1 -0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 2.0 6.4 0.4 -1.2 0.1 -1.2 2.2 0.2 1.1 -1.0 1.9 -0.6 0.3 1.0 1.6 0.4 -0.4 1.1 1.7 2.5 1.0 1.7 2.3 2.4 1.4 1.5
Pulse wave Arterial Stiffness index 0.3 0.4 1.7 -0.2 -0.1 -0.5 -0.4 1.0 0.5 0.3 -0.1 -0.1 -0.3 0.8 0.3 0.7 0.4 -0.5 0.4 0.9 1.1 0.5 1.3 0.2 0.7 -0.3 -0.7
Impedance of arm (left) 0.4 1.9 6.9 -1.1 1.3 0.2 1.1 -2.6 -1.0 -1.1 1.2 -0.9 0.7 -1.3 -0.7 -1.4 -0.1 0.4 -1.1 -1.6 -2.2 -0.6 -1.3 -2.4 -2.3 -1.3 -1.0
Arm fat mass (right) 0.3 1.3 7.3 0.7 -0.0 -0.9 0.4 0.1 0.6 1.0 0.3 -1.5 -0.2 0.9 1.0 1.4 1.4 -0.9 0.8 1.5 0.8 0.8 0.2 -0.2 -0.3 -2.5 -2.7
Trunk predicted mass 2.1 12.1 28.4 3.7 -0.3 -1.5 0.0 4.4 3.6 4.5 0.1 2.4 0.5 4.0 4.4 5.3 3.0 -0.2 4.3 5.2 4.8 4.2 3.7 4.8 3.9 -0.4 -1.8
Standing height 1.8 17.7 39.2 5.0 0.3 -2.2 0.3 4.9 4.0 5.3 0.8 3.8 1.2 4.6 5.4 6.2 3.4 0.1 5.4 6.3 5.8 5.4 5.0 5.3 4.7 -0.1 -1.8
Length of working week for main job 1.7 1.9 5.4 1.3 -0.8 0.1 -0.5 1.8 1.0 1.5 -0.7 2.0 -0.1 1.2 1.3 1.7 1.0 0.3 1.5 2.1 2.2 1.2 1.4 2.3 1.2 1.5 -0.6
Exposure to tobacco smoke at home 0.2 0.3 1.3 1.1 0.1 -0.7 0.5 -0.3 -0.2 0.6 0.3 -0.3 0.1 -0.6 0.4 0.1 0.3 -0.3 0.4 0.7 0.1 0.4 0.9 -0.0 -0.1 -0.6 -1.1
Breastfed as a baby 0.7 0.9 6.3 -1.4 0.6 0.6 0.8 -1.2 -0.3 0.1 0.5 -0.7 -0.2 -0.5 -0.4 -0.5 -0.3 -0.8 -0.7 -0.9 -1.1 -0.5 -0.6 -1.3 -1.6 -2.5 -1.2
Tense / ‘highly strung’ 0.5 0.9 4.9 0.1 1.1 1.0 1.2 -0.5 -0.5 0.6 1.3 0.9 1.7 -0.6 0.2 -0.3 0.6 2.2 -0.8 -0.7 -0.7 -0.2 -1.2 0.5 -1.0 0.7 -0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.6 0.9 3.7 -0.6 -0.6 0.3 -0.4 -0.8 -1.8 -1.2 -0.6 -0.4 -0.6 -1.9 -1.2 -1.4 -0.6 -0.1 -0.8 -0.8 -0.9 -1.2 -0.7 -1.5 -0.8 0.3 -0.3
Hair/balding pattern: Pattern 4 1.1 2.6 6.1 -2.0 -1.0 -0.3 -1.0 -1.7 -1.6 -2.3 -1.0 -0.5 -1.4 -1.6 -2.2 -2.3 -1.5 -1.3 -2.4 -2.0 -1.6 -2.1 -1.4 -2.5 -1.1 -0.2 0.9
Birth weight of first child 1.9 3.5 8.9 1.5 0.4 -1.6 0.5 2.2 2.1 2.5 0.7 1.5 1.1 1.7 2.5 2.9 1.7 0.9 2.2 2.2 2.4 2.7 1.7 3.0 2.0 0.2 -0.4
Peak expiratory flow (PEF) 0.7 1.7 4.2 1.0 -0.1 -0.9 -0.2 1.7 1.9 0.9 0.1 0.7 0.3 1.9 1.2 1.7 1.2 0.0 1.7 2.0 1.7 1.7 1.5 1.5 1.6 0.7 -0.3
Pulse wave reflection index 0.5 0.7 2.1 -1.3 -0.5 0.4 -0.8 0.1 -1.0 -1.4 -0.7 0.6 -0.4 -1.3 -1.2 -1.1 -0.2 -0.0 -0.7 -0.5 -0.2 -0.8 0.8 -0.6 -0.1 1.4 0.5
Ever highly irritable/argumentative for 2 days 0.5 0.6 3.2 1.0 0.8 0.7 0.6 -0.1 0.4 1.3 1.0 1.8 0.9 -0.1 1.2 0.8 0.7 0.4 0.5 0.6 0.0 0.9 -0.2 1.0 0.4 -0.3 -0.3
Loud music exposure frequency 1.3 1.4 3.9 -0.4 1.7 1.4 1.2 -1.9 -0.7 -0.2 1.3 0.9 1.1 -1.4 -0.6 -1.4 0.2 1.0 -0.7 -1.4 -1.7 -0.9 -2.0 -0.6 -1.7 0.2 0.9
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 4.7 -0.2 -0.5 -0.2 -0.5 0.7 -0.4 -0.7 -0.7 -0.2 -0.2 -0.3 -0.6 -0.4 -0.3 0.1 0.3 -0.2 0.6 -0.2 -0.3 0.6 0.5 2.2 1.3
Mouth/teeth dental problems: Bleeding gums 0.5 0.6 1.7 -1.0 1.0 0.3 0.8 -1.2 -0.7 0.0 0.9 0.7 0.8 -1.0 -0.1 -0.7 0.0 0.7 -1.1 -0.6 -1.3 -0.7 -1.2 -0.4 -0.8 0.0 0.0
Blood clot in the leg (DVT) 0.3 0.4 1.3 -0.8 1.0 -0.1 1.1 -0.4 0.7 0.3 1.0 -1.1 0.9 0.8 0.5 0.3 0.6 0.4 0.0 0.6 -0.1 0.4 -0.6 0.0 -0.1 -0.5 -1.0
Medication: Paracetamol 0.4 0.7 2.4 0.5 0.4 -1.1 0.4 0.5 0.8 0.9 0.6 -0.0 0.4 0.1 1.4 1.5 0.6 -0.3 0.9 1.0 0.8 1.5 0.6 0.2 0.3 -1.0 -1.4
Headache pain in last month 0.7 1.3 4.5 1.6 0.6 -1.8 0.8 -0.4 1.1 1.1 0.7 -1.0 0.2 1.2 1.7 1.3 1.3 -0.7 1.4 0.7 0.1 1.4 -0.2 0.6 -0.2 -1.5 -2.1
Medication for cholesterol, blood pressure or diabetes 1.2 1.9 5.6 -0.5 -2.1 -0.6 -2.4 1.4 -1.4 -1.9 -2.3 0.7 -2.0 -1.1 -1.5 -0.7 -2.1 -1.7 -0.6 -0.5 1.0 -0.8 1.0 0.0 1.1 1.4 1.1
Glaucoma (self-reported) 0.4 0.5 5.2 -0.1 -0.2 2.3 -0.2 0.1 -0.3 -0.4 -0.2 0.9 0.2 -1.3 -0.2 -0.2 -1.1 0.5 -0.3 -0.8 -0.1 0.1 -0.0 0.4 0.2 0.7 1.1
Gout (self-reported) 0.7 0.9 2.8 0.5 1.5 1.2 1.7 -1.4 0.6 0.5 1.5 0.3 1.3 0.5 0.5 -0.1 1.6 1.0 0.1 -0.0 -1.2 0.0 -0.4 -0.2 -1.3 -0.7 -0.9
Hypothyroidism/myxoedema (self-reported) 0.7 1.4 3.6 1.5 0.6 -1.6 0.1 0.9 1.1 1.2 0.3 0.0 0.0 0.5 1.5 1.8 0.9 -0.8 1.6 1.9 1.2 1.6 1.1 0.8 0.8 -1.4 -1.7
Medication: Amlodipine 2.1 3.0 6.4 1.4 2.1 -0.4 2.1 0.2 2.5 2.2 2.2 0.7 2.2 2.3 2.4 2.0 2.2 1.9 2.0 1.4 0.2 2.1 -0.2 1.3 -0.3 -1.5 -1.2
Medication: Ventolin 100micrograms inhaler 0.9 1.2 3.0 0.6 1.1 0.8 1.3 0.3 1.7 1.5 1.3 0.1 1.1 1.5 1.5 1.4 1.5 0.4 1.3 0.9 0.5 1.4 0.5 0.9 -0.1 -0.9 -1.3
Birth weight 1.5 3.2 9.3 1.7 -0.4 -1.4 -0.5 2.8 1.5 2.1 -0.4 0.7 -0.1 1.9 1.6 2.3 1.0 -0.3 2.2 2.9 3.0 1.8 2.5 2.1 2.4 0.5 -0.5
Chronic bronchitis/emphysema (mother) 0.7 0.8 3.1 -0.4 -0.9 0.8 -0.7 0.3 -1.7 -0.6 -0.8 -1.0 -0.8 -1.8 -0.9 -0.7 -1.6 -0.7 -1.3 -1.1 -0.1 -0.9 -0.2 -0.4 0.2 0.5 0.3
High blood pressure (siblings) 2.9 4.1 8.1 2.5 2.6 -1.1 2.6 -0.3 2.5 2.8 2.7 0.3 2.3 2.4 2.8 2.1 2.8 1.3 2.0 1.9 0.5 2.3 -0.3 1.1 -0.1 -2.0 -2.1
Forced vital capacity (FVC), Best measure 0.5 1.8 6.4 0.0 -1.4 -0.2 -1.4 2.0 0.1 1.0 -1.3 1.6 -1.0 0.1 0.9 1.4 -0.0 -1.0 1.0 1.2 2.3 1.0 1.4 2.0 2.5 1.1 1.7
Body fat percentage 0.3 1.1 7.9 0.2 0.3 -1.1 0.5 -0.5 -0.0 0.5 0.5 -1.9 -0.1 0.2 0.6 0.7 1.1 -0.8 0.5 1.0 0.2 0.5 -0.1 -1.0 -1.0 -2.8 -2.5
Leg fat percentage (right) 0.2 0.7 5.7 0.3 0.4 -0.6 0.7 -0.3 0.0 0.6 0.7 -1.1 0.2 0.3 0.7 0.8 1.4 -0.2 0.6 1.0 0.2 0.5 -0.3 -0.4 -0.8 -2.4 -1.7
Arm fat-free mass (right) 1.8 9.3 22.3 3.2 -0.8 -2.1 -0.6 4.1 3.0 3.8 -0.4 1.5 -0.2 3.7 3.6 4.5 2.4 -0.8 3.6 4.7 4.5 3.5 3.4 3.9 3.5 -0.4 -1.8
Exposure to tobacco smoke outside home 2.3 3.0 10.0 1.7 0.7 -3.2 0.9 1.3 2.2 2.1 1.0 1.3 1.1 2.2 2.1 2.0 1.5 0.3 2.2 2.1 1.6 2.2 2.0 1.9 1.4 0.4 -1.1
Comparative body size at age 10 0.1 0.2 1.5 0.7 0.4 0.7 -0.3 0.5 0.6 -0.4 0.2 0.2 0.5 0.5 -0.0 0.1 -0.4 0.8 0.4 0.1 0.5 0.1 0.0 0.4 -0.1 1.2 0.6
Number of full brothers 2.4 3.1 9.2 1.8 1.5 0.7 2.1 0.2 2.4 3.0 1.7 0.7 1.5 2.3 2.5 2.1 1.8 0.7 1.8 2.0 0.9 1.9 0.9 1.4 0.5 -2.0 -2.1
Worry too long after embarrassment 0.5 0.9 2.9 -0.5 1.6 0.8 1.7 -0.5 -0.6 -0.6 1.3 1.2 1.6 -0.8 -0.2 -0.4 1.0 1.7 -0.3 -0.2 -0.4 0.2 -0.1 -0.8 -1.6 0.1 -0.6
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.2 1.3 0.0 0.2 -0.4 0.4 -0.2 0.1 -0.3 0.3 1.1 0.6 -0.2 0.1 -0.0 0.6 0.7 -0.0 0.1 -0.5 0.5 -0.3 -0.1 -0.5 0.9 -0.4
Wheeze or whistling in the chest in last year 0.6 1.1 5.5 0.3 0.3 -1.2 0.6 -1.6 1.4 0.3 0.5 -0.5 -0.1 1.6 0.5 -0.0 0.7 -0.7 0.0 -0.3 -1.3 0.3 -1.3 -0.9 -1.5 -1.8 -2.4
Number of children fathered 1.1 1.3 4.9 0.5 -1.2 0.8 -1.2 2.0 0.1 0.9 -1.0 1.2 -0.8 0.5 0.3 0.7 -0.7 -0.8 0.4 0.8 2.2 0.2 1.6 1.6 1.9 1.0 1.2
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 2.2 -0.1 1.4 -1.5 1.2 0.1 1.1 0.9 1.4 1.1 1.2 1.3 0.8 0.7 0.6 0.5 0.4 -0.0 0.3 0.8 0.9 0.7 0.1 -0.5 -1.1
Age at first live birth 2.2 3.9 8.3 -1.9 -2.1 0.9 -2.6 -0.4 -2.1 -2.6 -2.3 -0.3 -2.1 -1.9 -2.9 -2.6 -2.7 -1.3 -2.3 -2.7 -0.7 -2.6 -0.9 -1.3 -0.1 1.6 2.3
Pulse wave peak to peak time 0.1 0.2 0.9 0.6 0.2 0.2 0.5 -0.6 0.0 0.2 0.3 0.5 0.5 -0.2 0.2 -0.1 0.0 0.6 0.1 -0.2 -0.5 0.0 -0.9 0.4 -0.2 0.2 0.4
Health satisfaction 0.5 0.7 2.5 -0.0 1.6 0.4 1.2 -0.6 0.5 0.3 1.4 0.1 0.9 0.7 0.4 0.4 0.9 0.2 0.3 -0.0 -0.0 0.5 0.1 -0.7 -1.1 -1.5 -1.5
Shortness of breath walking on level ground 1.9 2.2 7.2 0.7 2.2 1.0 2.7 -1.2 1.5 1.7 2.5 -0.2 2.3 1.4 1.5 0.8 2.5 1.8 0.6 0.4 -0.7 1.1 -0.4 0.1 -1.6 -1.5 -1.1
Qualifications: College or University degree 0.2 0.7 4.7 -0.2 0.9 0.3 0.7 -0.8 0.7 0.6 0.7 -0.5 0.5 0.8 0.5 0.3 0.9 0.2 0.3 -0.2 -1.0 0.6 -0.6 -0.1 -1.3 -1.3 -2.2
Eye problems/disorders: None of the above 0.1 0.2 0.6 0.2 -0.0 0.2 -0.2 -0.0 -0.8 -0.5 0.1 0.2 -0.3 -0.6 -0.7 -0.6 0.0 -0.6 -0.3 -0.2 0.0 -0.8 0.5 -0.5 0.1 -0.3 -0.2
Mouth/teeth dental problems: Loose teeth 0.3 0.3 1.8 -1.4 0.4 -0.7 0.5 -0.5 -0.4 -0.7 0.3 0.9 -0.1 -0.1 -0.6 -0.5 0.1 -0.7 -0.8 -0.3 -0.3 -0.6 -0.2 -0.8 -0.1 -0.6 -0.1
Emphysema/chronic bronchitis 0.4 0.4 1.7 1.3 0.3 0.8 0.4 -0.1 0.2 0.7 0.3 -0.9 0.7 0.2 0.4 0.2 1.1 1.0 0.2 -0.4 -0.5 0.0 -0.9 0.6 0.2 0.8 0.9
Medication for pain relief, constipation, heartburn 0.7 1.2 6.5 -1.0 -1.3 1.1 -1.1 0.3 -0.6 -1.0 -1.4 0.2 -0.9 -0.4 -1.5 -1.4 -0.9 0.0 -0.9 -0.6 -0.1 -1.6 -0.0 0.5 0.7 2.5 2.1
Neck or shoulder pain in last month 2.2 3.1 8.7 2.6 -0.2 -2.9 0.1 0.9 1.6 2.6 0.2 0.5 -0.0 2.0 2.7 2.4 0.9 -1.0 2.3 2.0 1.3 2.3 0.7 1.6 1.1 -1.7 -2.6
Medication: Blood pressure 0.8 1.5 4.0 0.7 1.8 0.7 2.0 -0.8 1.1 1.9 1.7 -0.4 1.6 1.0 1.5 1.0 2.0 1.7 0.4 0.6 -0.4 0.7 -0.7 0.3 -0.8 -1.3 -1.1
Angina (self-reported) 1.2 1.6 3.3 1.8 1.3 -0.1 1.4 1.0 1.2 1.8 0.9 1.8 1.2 1.2 1.8 1.5 1.6 0.9 1.3 0.9 1.0 1.5 0.9 1.3 0.8 -0.2 -0.8
Migraine (self-reported) 0.2 0.3 1.4 0.3 0.3 0.1 0.2 0.3 0.8 0.4 0.0 -0.4 -0.1 1.1 0.5 0.5 -0.0 -0.3 0.7 0.0 0.4 1.0 0.6 -0.2 -0.1 -0.4 -1.2
Medication: Ibuprofen 0.5 0.6 2.1 -0.1 -0.9 0.7 -0.7 -0.7 -1.1 -1.2 -0.7 -1.1 -0.7 -0.9 -0.9 -0.7 -0.5 -0.4 -0.7 -0.3 -0.5 -0.5 -0.8 -1.4 -0.7 -0.1 0.2
Medication: Allopurinol 0.3 0.4 1.9 1.0 0.4 0.4 0.5 -0.3 0.8 0.4 0.4 0.5 0.1 1.0 0.4 0.2 0.9 -0.3 0.6 0.6 -0.0 0.3 0.7 0.1 -0.3 -0.7 -1.4
Medication: Omeprazole 1.6 1.9 6.0 1.0 1.9 -1.1 1.9 -0.8 1.3 1.6 2.3 0.0 1.7 1.0 1.7 1.2 2.1 0.7 0.8 0.3 -0.1 1.3 -0.5 0.3 -0.6 -2.4 -1.9
Medication: Seretide 50 evohaler 0.3 0.3 1.0 0.6 -0.8 0.1 -0.9 0.8 -0.3 -0.5 -1.0 0.5 -0.7 0.0 -0.6 -0.5 -0.8 -0.1 -0.2 -0.3 0.7 -0.5 0.1 -0.1 0.7 0.7 0.2
Mean time to correctly identify matches 0.6 1.2 3.7 -0.9 0.6 0.8 0.2 -1.3 -1.3 -1.7 0.4 -0.3 0.2 -1.6 -1.4 -1.7 -0.1 0.2 -1.7 -0.6 -1.4 -1.5 -0.7 -1.2 -0.5 0.1 1.9
Heart disease (mother) 1.1 1.4 5.0 0.1 -0.0 -0.6 -0.2 1.6 0.7 1.4 0.3 1.0 0.5 0.1 1.6 1.4 0.3 0.3 1.7 0.5 1.5 1.4 0.9 2.2 2.0 0.3 2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 3.2 0.8 1.0 -0.4 0.9 0.1 0.9 0.6 1.1 0.4 1.0 0.2 0.9 1.0 1.8 0.6 1.0 0.3 0.4 1.1 0.5 0.3 -0.3 -0.7 -1.6
Whole body fat mass 0.5 2.0 8.0 1.0 0.2 -1.7 0.5 0.6 1.0 1.6 0.5 -1.2 -0.1 1.3 1.6 2.0 1.6 -1.0 1.4 2.2 1.3 1.4 0.7 0.2 0.1 -2.8 -2.8
Leg fat mass (right) 0.4 1.7 5.5 1.1 0.1 -1.3 0.5 0.8 0.9 1.5 0.4 -1.0 0.1 1.3 1.6 2.0 1.7 -0.6 1.4 2.2 1.4 1.3 0.5 0.5 0.2 -2.3 -2.3
Arm predicted mass (right) 2.2 11.0 26.1 3.5 -0.8 -2.1 -0.6 4.6 3.2 4.0 -0.4 1.8 -0.1 3.9 3.9 4.9 2.4 -0.8 4.1 5.1 5.0 3.8 3.9 4.4 4.0 -0.1 -1.7
Pulse rate, automated reading 0.3 1.1 6.4 -0.8 -0.2 -0.1 -0.2 -1.2 -1.4 -1.1 -0.3 -2.5 -0.7 -0.8 -0.8 -0.7 -0.1 -0.8 -1.0 -0.0 -0.9 -0.9 -1.2 -1.6 -1.2 -1.6 -1.2
Alcohol intake frequency. 0.7 1.7 5.8 1.3 2.1 0.7 2.4 -1.1 0.8 0.9 1.9 0.0 2.0 0.7 0.7 0.4 2.1 2.0 0.8 0.3 -1.0 0.4 -1.4 -0.4 -1.5 -1.3 -1.2
Comparative height size at age 10 1.9 10.4 21.6 4.5 2.8 -0.6 2.7 0.9 3.6 4.4 3.0 1.5 2.8 4.0 4.6 4.4 4.4 1.3 3.9 3.9 2.0 4.1 1.5 3.0 0.7 -2.6 -3.4
Number of full sisters 1.0 1.3 3.9 -1.3 -1.9 0.2 -1.6 -0.1 -1.6 -0.9 -1.4 0.4 -1.7 -2.0 -0.9 -0.8 -1.5 -1.9 -1.2 -0.8 -0.2 -1.0 0.1 -0.3 0.3 0.5 -0.0
Suffer from ‘nerves’ 1.5 2.4 8.1 -1.6 -0.5 -2.5 -0.1 -1.8 -1.8 -1.5 -0.1 -0.7 -0.8 -1.7 -1.0 -1.4 -1.2 -1.6 -1.6 -1.9 -1.8 -0.9 -1.5 -1.9 -1.8 -0.8 -2.8
Overall health rating 2.7 5.8 14.1 1.1 2.7 -1.5 2.8 0.5 3.8 2.5 2.8 0.8 2.6 3.6 3.0 2.9 3.3 1.6 2.2 2.6 1.1 3.0 1.7 1.0 -0.4 -2.3 -3.1
Chest pain or discomfort 0.1 0.1 0.7 0.2 -0.0 0.4 0.5 -0.0 -0.3 0.5 0.2 0.3 0.0 -0.2 0.2 0.0 0.1 0.1 0.2 0.1 0.2 -0.4 0.3 -0.5 -0.7 -0.8 -0.9
Had major operations 0.9 1.1 5.5 -0.5 0.9 1.8 1.0 -0.3 0.2 0.3 1.1 1.0 1.6 -0.2 -0.2 -0.5 0.8 2.3 -0.3 -0.2 -0.3 -0.4 -1.0 0.7 -0.7 2.2 1.3
Age at last live birth 1.3 1.9 4.5 -2.1 -0.8 1.7 -1.4 -1.1 -1.1 -1.4 -1.1 -0.8 -1.2 -1.2 -1.8 -1.8 -1.5 -0.8 -1.5 -1.8 -1.0 -1.5 -1.9 -1.6 -0.7 0.8 0.9
Family relationship satisfaction 0.2 0.2 1.3 -0.3 0.2 0.1 -0.0 0.5 -0.0 0.6 0.4 1.2 -0.0 -0.4 0.4 0.5 -0.1 -0.5 -0.3 0.4 0.3 0.1 0.8 0.2 0.4 -1.0 -0.4
Leg pain on walking 2.0 2.5 6.7 2.0 1.4 0.4 1.4 0.1 2.3 2.6 1.5 1.6 1.6 2.1 2.3 2.0 1.8 1.4 1.7 1.4 0.6 1.9 0.5 2.0 0.1 -0.7 -0.6
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 5.2 0.5 -0.3 0.7 -0.0 0.4 0.2 0.4 0.1 2.3 0.6 0.1 0.3 0.0 -0.0 0.9 0.1 0.1 0.2 0.1 -0.1 1.2 0.6 1.7 0.9
Commuting to job workplace: Car/motor vehicle 1.5 1.7 5.4 -0.0 -2.3 -0.4 -2.0 1.0 -0.9 -1.5 -2.2 0.6 -2.1 -0.5 -1.6 -0.8 -1.8 -1.7 -1.0 -0.2 0.8 -0.9 1.9 -0.8 0.8 0.5 -0.1
Illness, injury, bereavement, stress in last 2 years 2.4 3.0 6.6 -2.6 -1.7 0.4 -2.1 -0.3 -2.4 -1.9 -1.9 -1.7 -2.1 -2.1 -2.2 -1.8 -2.2 -1.7 -1.9 -1.8 -0.4 -2.1 -0.5 -1.8 -0.0 -0.4 1.2
Medication: Aspirin 0.5 0.7 1.8 0.5 1.4 0.2 1.1 -0.4 0.5 0.9 1.3 1.3 1.1 0.5 0.9 0.6 1.0 0.8 0.7 0.0 -0.2 0.8 0.1 -0.1 -0.4 -1.2 -1.0
Supplements: Vitamin C 0.5 0.6 1.7 -0.6 1.2 0.5 0.9 -1.1 -0.1 -0.2 0.8 -1.0 0.5 0.1 -0.4 -0.6 0.4 0.4 -0.6 -0.1 -1.1 -0.4 -0.9 -0.8 -1.3 -1.2 -1.0
Knee pain experienced in last month 0.9 1.4 3.6 1.5 1.2 -1.2 1.8 -0.9 0.4 1.8 1.4 -0.2 1.6 0.5 1.3 0.6 1.5 1.6 0.2 0.1 -1.0 0.5 -1.9 0.4 -1.4 -0.7 -1.2
Hypertension (Self-reported) 2.0 5.5 13.5 3.0 1.9 -0.1 2.3 0.8 3.2 3.1 2.1 0.7 2.4 2.9 3.3 3.1 3.7 2.0 3.0 2.7 1.2 3.1 0.5 2.2 0.1 -1.1 -2.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 2.0 2.3 8.1 2.1 1.4 -1.4 1.6 -0.2 1.8 1.5 1.5 1.1 1.4 2.2 1.7 1.3 2.3 0.6 1.3 1.2 0.1 1.6 1.3 0.6 -0.5 -1.3 -2.8
Illnesses of father: Heart disease 0.7 0.9 2.0 1.3 0.9 -0.3 1.2 0.4 1.2 0.9 1.1 1.4 1.3 1.4 0.9 0.8 1.3 0.8 0.9 0.9 0.4 0.8 0.3 1.2 0.5 1.1 0.3
Illnesses of siblings: Diabetes 1.9 2.4 7.5 -1.7 -0.4 -0.8 -0.6 -1.4 -1.6 -2.2 -0.7 -2.1 -1.3 -1.6 -2.0 -1.8 -1.5 -1.6 -2.1 -1.5 -1.3 -1.7 -1.1 -2.7 -0.8 -1.1 0.4
Smoking status: Previous 1.1 1.6 5.2 1.7 1.0 -1.6 0.8 0.6 1.1 2.3 1.1 0.5 1.1 0.7 2.1 1.6 1.3 0.7 1.8 0.8 0.8 1.5 -0.1 2.0 1.2 -0.3 0.1
Forced expiratory volume in 1-second (FEV1), predicted 2.2 4.7 12.0 3.5 0.0 -0.7 0.3 2.2 1.9 2.5 0.5 2.9 1.1 2.5 2.4 2.9 2.4 1.1 2.7 2.8 2.7 2.7 1.9 2.7 2.4 0.7 0.8
Whole body fat-free mass 1.8 10.5 25.4 3.5 -0.2 -1.4 0.1 4.0 3.4 4.3 0.2 1.7 0.5 3.8 4.1 5.0 3.0 -0.3 4.1 5.0 4.6 3.9 3.3 4.2 3.4 -0.7 -2.0
Leg fat-free mass (right) 1.3 6.8 18.0 3.0 0.2 -1.2 0.6 2.8 2.9 3.6 0.6 0.4 0.6 3.2 3.4 4.1 2.8 -0.2 3.2 4.2 3.5 3.1 2.3 3.0 2.3 -1.3 -2.2
Arm fat percentage (left) 0.4 1.6 9.4 -0.3 0.6 -0.5 0.8 -1.6 -0.3 0.0 0.7 -2.5 -0.0 -0.2 0.1 0.1 1.1 -0.6 -0.3 0.2 -0.8 -0.2 -1.1 -1.7 -1.9 -3.1 -2.8
Average weekly red wine intake 1.9 2.8 5.4 1.5 1.7 -1.2 1.4 0.8 2.3 2.0 1.7 1.7 2.0 2.3 2.2 1.8 1.9 1.4 2.3 1.1 1.1 2.2 0.1 2.3 1.0 0.2 0.5
Handedness (chirality/laterality): Left-handed 0.5 0.6 2.2 -0.2 1.1 0.3 0.9 -1.4 -0.8 -0.5 0.9 -0.1 0.2 -0.2 -0.7 -0.8 0.6 -0.4 -0.3 -0.7 -0.9 -0.9 -0.5 -1.2 -1.5 -0.8 -0.9
Mood swings 0.4 0.7 3.0 0.1 1.0 1.5 1.2 0.3 -0.6 0.4 1.1 0.6 1.4 -0.6 0.5 0.6 1.7 1.7 0.3 0.5 0.6 0.3 0.2 0.1 -0.5 0.5 -0.8
Loneliness, isolation 0.4 0.6 1.6 0.1 -0.3 -1.3 -0.1 0.4 0.5 1.0 -0.0 1.3 -0.5 0.3 1.1 0.9 -0.1 -1.2 0.6 0.5 0.9 0.9 0.7 0.4 0.6 -0.6 -1.2
Long-standing illness, disability or infirmity 0.7 1.0 3.9 0.4 1.7 0.1 1.8 -1.0 0.6 0.6 1.5 -0.2 1.1 0.5 0.7 0.5 1.5 0.8 0.2 0.5 -0.4 0.3 -0.5 -0.5 -1.2 -2.0 -1.6
Ever had bowel cancer screening 0.4 0.5 2.1 -0.5 1.1 -0.6 0.5 -0.5 -0.3 -0.7 0.7 -0.9 0.2 -0.7 -0.6 -0.5 0.6 -0.3 -1.3 -0.3 -0.3 -0.5 0.0 -1.4 -0.4 -1.1 -0.0
Diabetes diagnosed by doctor 1.0 1.6 5.7 0.4 2.1 0.7 2.3 -1.1 0.6 0.7 2.1 -0.3 1.8 0.6 0.8 0.5 1.5 1.4 0.0 0.0 -0.8 0.6 -0.6 -1.0 -1.6 -2.4 -1.4
Ever had stillbirth, spontaneous miscarriage or termination 1.4 1.5 3.7 1.6 0.8 -0.4 0.9 1.1 1.8 1.9 0.8 0.6 0.8 1.6 1.6 1.9 0.7 0.2 1.3 1.7 1.0 1.7 0.5 1.4 1.1 -0.6 -0.7
Friendships satisfaction 0.4 0.5 1.9 -0.1 0.9 -0.4 0.5 0.3 0.6 0.7 1.0 1.4 0.6 0.8 0.7 0.8 0.9 0.1 0.4 0.5 0.4 0.7 1.1 0.3 -0.4 -1.1 -1.0
Qualifications: nursing, teaching 0.9 1.4 5.5 -0.2 -0.4 -1.1 -0.6 2.2 0.1 0.5 -0.4 1.5 -0.3 0.5 0.5 1.2 0.0 -0.5 1.3 1.9 2.1 0.8 2.4 1.6 1.6 0.8 0.2
Commuting to job workplace: Walk 1.7 1.8 6.1 0.7 2.5 -0.1 2.1 -0.8 1.5 1.2 2.5 -0.1 2.4 1.3 1.3 0.9 1.9 1.9 0.9 0.3 -0.6 1.3 -0.6 0.4 -0.9 -0.6 -0.5
Eye problems/disorders: Cataract 0.3 0.3 0.8 0.1 0.6 -0.4 0.7 -0.5 0.7 0.7 0.6 0.2 0.8 0.6 0.9 0.6 0.4 0.9 0.2 0.0 -0.7 0.8 -0.6 0.3 -0.5 0.1 -0.7
Mouth/teeth dental problems: Mouth ulcers 0.9 1.4 4.2 1.8 1.7 0.6 1.5 0.4 0.9 1.3 1.4 1.3 1.6 0.8 1.3 1.3 2.0 1.4 1.2 1.2 0.4 1.3 0.7 0.9 -0.1 -0.1 0.3
Medication for cholesterol 1.3 2.0 5.8 -0.5 -2.4 1.9 -2.2 1.5 -1.0 -0.3 -2.1 1.0 -1.8 -0.6 -1.0 -0.6 -1.9 -1.0 -0.4 0.2 1.0 -1.1 1.0 0.6 1.7 2.4 1.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.4 2.0 -0.8 0.4 -1.1 0.4 -0.5 0.5 -0.7 0.2 0.3 0.1 0.5 -0.3 -0.6 -1.4 -0.2 -0.2 -0.8 -0.3 0.1 0.2 -0.8 -0.6 0.3 -1.4
Back pain experienced in last month 0.2 0.3 2.0 1.1 0.1 -0.4 0.1 -0.0 0.1 0.8 0.2 0.8 -0.0 0.4 0.7 0.7 1.4 -0.3 0.5 0.6 0.3 0.4 0.3 0.5 0.1 -0.7 -0.7
Mineral and other dietary supplements 0.3 0.4 1.3 0.8 0.3 1.1 0.4 -0.8 1.1 0.5 0.3 -0.4 0.4 0.8 0.4 0.3 0.9 0.6 0.4 -0.2 -0.8 0.5 -0.8 -0.0 -0.6 -0.6 -0.6
Breast cancer (self-reported) 0.6 0.8 4.0 -0.8 1.0 2.0 0.8 -0.6 -0.7 -0.1 0.8 -0.1 0.8 -1.4 -0.5 -0.5 0.0 1.0 -1.0 -1.0 -0.7 -0.7 -1.4 -0.1 -0.4 -0.0 1.3
Asthma (self-reported) 1.0 1.9 7.7 -0.6 0.9 1.5 0.8 -2.1 -0.2 -1.2 0.7 -1.8 0.1 0.2 -1.1 -1.4 0.4 -0.1 -0.8 -1.0 -1.8 -1.0 -1.4 -2.8 -2.7 -2.0 -1.5
Osteoporosis (self-reported) 0.5 0.7 2.2 0.4 -0.2 -0.4 -0.1 1.0 0.8 0.9 -0.0 1.5 0.1 0.8 1.0 0.9 0.3 -0.2 1.0 0.9 1.0 0.8 1.0 1.4 1.4 0.5 0.3
Osteoarthritis (self-reported) 0.6 0.7 2.5 0.6 -1.5 -1.0 -1.3 1.5 -0.5 0.1 -1.6 0.7 -1.1 -0.3 0.1 0.4 -0.7 -0.6 0.1 0.1 1.0 0.1 0.6 0.8 1.1 0.9 0.1
Medication: Aspirin 0.6 0.8 2.5 0.5 1.6 0.0 1.3 -0.8 0.6 0.8 1.5 0.8 1.3 0.5 0.9 0.4 1.2 0.9 0.4 -0.0 -0.6 0.8 -0.4 -0.3 -0.7 -1.4 -1.2
Medication: Gliclazide 1.1 1.2 6.2 0.1 0.8 -1.3 0.7 -0.0 1.7 1.3 0.7 -0.6 0.4 1.4 1.6 1.6 0.7 -0.6 0.9 0.2 -0.1 1.8 0.5 0.2 0.3 -2.5 -1.6
Illnesses of father: None of the above (group 1) 0.3 0.3 2.2 -0.2 -0.7 -0.2 -1.5 0.4 -0.5 -0.3 -1.1 0.5 -1.0 -0.4 -0.4 -0.3 -0.9 -0.6 -0.1 -0.1 0.3 -0.3 -0.0 0.2 0.5 0.5 0.7
Smoking status: Current 0.6 1.0 3.2 1.4 0.6 -0.9 0.6 0.1 1.3 1.2 0.9 0.9 0.7 1.8 1.2 1.2 1.5 0.2 0.9 1.1 -0.4 1.0 0.1 1.2 0.0 -0.0 -1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.4 3.0 8.5 -1.9 -2.5 0.5 -2.6 2.0 -1.4 -1.4 -2.7 0.7 -2.1 -1.7 -1.2 -0.5 -1.7 -1.1 -1.2 -0.3 1.6 -0.9 1.3 0.8 2.1 2.3 2.9
Whole body water mass 1.7 10.0 24.5 3.4 -0.2 -1.3 0.1 3.9 3.3 4.2 0.2 1.6 0.5 3.6 4.0 4.9 2.9 -0.3 3.9 4.9 4.5 3.8 3.3 4.1 3.4 -0.8 -1.9
Leg predicted mass (right) 1.2 6.4 16.8 2.9 0.2 -1.1 0.5 2.7 2.9 3.5 0.5 0.3 0.6 3.1 3.2 4.0 2.7 -0.2 3.1 4.1 3.4 3.0 2.2 2.8 2.2 -1.3 -2.2
Arm fat mass (left) 0.3 1.4 9.0 0.5 0.1 -1.1 0.4 -0.2 0.6 0.9 0.3 -1.7 -0.3 0.9 0.9 1.3 1.4 -1.1 0.7 1.5 0.6 0.7 0.0 -0.4 -0.6 -2.7 -3.0
Number of self-reported non-cancer illnesses 0.6 1.1 3.9 0.1 1.6 -1.1 1.5 -0.9 0.9 0.6 1.5 -0.1 1.2 0.8 0.9 0.5 1.5 0.5 0.4 0.8 -0.3 0.9 -0.1 -0.3 -1.6 -1.5 -2.0
Average weekly champagne plus white wine intake 0.3 0.4 1.5 0.8 0.5 0.2 0.1 -0.1 0.7 1.1 0.4 0.7 0.2 1.1 0.8 0.8 0.8 0.1 0.4 0.7 0.3 0.6 0.7 0.7 -0.4 -1.2 -0.8
Miserableness 0.7 1.2 11.3 -1.1 0.7 -1.8 0.7 -0.1 -0.0 0.6 0.9 -0.7 0.2 -0.3 1.0 1.2 1.0 -0.9 0.1 0.9 0.6 0.9 0.8 -0.8 -0.2 -1.8 -3.4
Guilty feelings 1.1 1.6 4.3 -1.0 1.6 0.8 1.4 -2.0 -1.0 -0.4 1.5 0.5 1.3 -1.7 -0.5 -1.2 0.6 1.1 -1.1 -1.9 -1.7 -0.7 -1.8 -1.2 -2.1 0.1 0.0
Wears glasses or contact lenses 0.6 0.7 1.4 0.6 1.2 0.9 1.0 0.4 0.4 0.9 0.9 0.8 0.9 0.4 0.7 0.6 1.2 0.7 0.9 1.1 0.4 0.9 0.5 0.7 0.1 -0.9 1.2
Ever taken oral contraceptive pill 0.2 0.2 1.0 0.6 0.5 -0.5 0.1 -0.4 0.5 0.4 0.3 0.6 0.1 0.4 0.6 0.3 0.3 -0.4 0.9 0.4 -0.5 0.7 0.0 -0.2 -0.2 -0.0 -1.0
Hearing aid user 0.6 0.7 2.5 -1.6 0.4 -0.4 -0.2 -1.1 -0.7 -1.1 0.1 -1.4 -0.4 -0.7 -0.5 -0.6 -0.4 -0.8 -0.9 -0.6 -0.7 -0.6 -0.3 -1.4 -0.6 -1.1 -0.8
Mother’s age at death 0.3 0.4 1.5 0.2 0.5 0.9 0.7 -1.1 0.5 -0.1 0.7 0.3 0.3 0.6 0.2 0.1 0.1 -0.2 -0.2 0.1 -1.1 0.3 -1.0 -0.7 -0.7 -1.2 -1.0
Financial situation satisfaction 0.6 0.7 2.0 0.5 0.8 -0.7 0.8 0.9 0.2 1.4 0.8 0.6 0.6 0.1 1.3 1.3 0.2 -0.2 0.3 1.0 0.6 1.1 1.3 1.0 0.5 -0.6 -0.8
Tinnitus: Yes, now most or all of the time 1.8 2.1 5.6 0.1 2.2 -0.3 1.7 -1.9 1.5 1.1 2.2 -0.4 1.5 0.9 1.5 1.0 2.1 -0.0 0.5 -0.2 -1.6 1.3 -1.7 -0.3 -1.4 -2.4 -2.4
Commuting to job workplace: Public transport 1.3 1.5 4.3 -1.4 1.6 0.6 1.8 -1.6 -0.3 -0.0 1.6 -1.5 1.5 -0.5 -0.3 -0.7 1.2 2.1 -1.2 -0.0 -1.2 -0.8 -1.7 -1.0 -2.0 -1.0 -0.2
Eye problems/disorders: Glaucoma 0.4 0.5 3.4 -0.5 -0.7 1.6 -0.5 0.4 -0.5 -0.2 -0.6 0.3 -0.1 -1.3 -0.2 -0.1 -1.2 0.4 -0.2 -0.7 0.3 0.1 -0.0 0.5 0.6 0.6 1.8
Medication: Blood pressure 1.7 3.2 8.0 2.1 2.5 -0.6 2.4 0.0 1.9 1.8 2.4 0.9 2.5 1.3 2.3 2.0 2.8 1.8 2.2 1.4 0.3 2.4 -0.4 1.3 -0.5 -0.9 -1.3
Pain type(s) experienced in last month: Hip pain 3.3 4.1 10.6 3.2 1.4 0.1 1.8 1.0 2.3 2.5 1.4 1.8 1.8 2.4 2.6 2.7 2.8 1.7 2.8 2.9 1.2 2.6 0.5 2.0 0.1 -0.4 -1.7
Supplements: Fish oil (including cod liver oil) 0.5 0.6 4.2 -0.2 0.1 -2.1 -0.1 1.3 0.1 -0.1 -0.1 0.3 -0.3 0.6 0.2 0.4 0.1 -0.8 0.5 0.7 1.5 0.4 1.3 0.7 1.2 0.4 0.1
High cholesterol (Self-reported) 0.7 1.2 4.0 -1.7 0.1 0.2 0.1 -2.0 -0.6 -0.8 0.1 -0.3 -0.3 -0.8 -0.8 -1.6 -1.1 -0.5 -1.5 -1.6 -1.8 -1.1 -1.6 -1.3 -1.2 -0.5 0.4
Medication: Bendroflumethiazide 1.2 1.8 7.8 0.7 1.9 0.6 2.0 -0.6 0.6 1.8 2.0 -0.3 1.9 0.1 1.6 1.3 2.8 1.5 1.6 1.3 -0.4 1.5 -0.1 0.1 -0.8 -1.3 -0.7
Medication: Paracetamol 0.7 1.1 3.4 0.8 0.6 -1.0 0.6 0.9 1.1 1.3 0.9 0.8 0.9 0.3 1.7 1.7 1.1 0.3 1.2 1.1 1.1 1.9 1.2 0.8 0.7 -0.5 -0.6
Medication: Lisinopril 0.1 0.1 0.4 0.5 0.4 0.1 0.3 -0.0 -0.2 0.1 0.4 0.6 0.5 -0.4 0.4 0.0 0.1 0.3 0.0 -0.4 -0.0 0.2 0.2 0.4 0.1 0.1 -0.5
Medication: Atorvastatin 1.3 1.6 4.4 -0.0 2.0 -1.7 1.7 -0.8 1.5 0.2 1.9 -0.5 1.2 1.6 0.9 0.9 1.4 -0.4 1.1 0.4 0.1 1.4 0.8 -0.4 -0.5 -1.9 -2.1
Illnesses of father: High blood pressure 0.6 0.7 2.8 0.4 0.6 0.1 1.0 0.0 0.7 0.9 1.0 -1.7 1.3 0.6 1.0 0.8 1.3 1.3 0.4 -0.0 0.3 0.6 -1.0 0.9 0.2 -0.2 0.6
Alcohol drinker status: Never 0.6 0.7 5.2 0.4 -0.0 2.3 -0.2 -0.2 -0.7 -1.2 -0.3 -0.1 0.3 -0.6 -1.2 -0.9 0.5 1.3 -0.6 -0.6 -0.5 -0.9 -0.7 -0.4 -0.5 0.8 1.5
Ever smoked 2.3 4.0 10.5 2.2 1.9 -1.6 1.7 0.8 2.4 3.2 2.0 1.4 2.0 2.1 2.9 2.6 2.8 1.2 2.5 1.9 0.6 2.3 -0.6 3.1 1.2 0.1 -0.5
Basal metabolic rate 1.5 8.5 21.2 3.2 -0.1 -1.5 0.3 3.3 3.1 3.9 0.4 1.0 0.4 3.5 3.8 4.6 2.9 -0.4 3.7 4.6 4.0 3.5 2.8 3.5 2.8 -1.3 -2.3
Leg fat percentage (left) 0.2 0.7 4.8 0.3 0.2 -0.9 0.4 0.1 0.0 0.6 0.5 -1.4 0.1 0.4 0.6 0.8 1.2 -0.4 0.6 1.1 0.4 0.4 0.0 -0.4 -0.5 -2.2 -1.5
Arm fat-free mass (left) 1.6 8.3 20.1 3.1 -0.7 -1.5 -0.5 3.8 2.8 3.6 -0.2 1.5 -0.1 3.3 3.5 4.4 2.2 -0.8 3.6 4.5 4.2 3.3 3.2 3.8 3.3 -0.4 -1.6
Number of operations (self-reported) 2.1 3.1 5.7 2.1 1.7 -0.2 1.8 1.2 1.5 2.4 1.8 2.3 2.4 1.3 2.3 1.9 2.0 2.3 1.7 1.8 1.1 2.1 0.8 2.2 1.1 1.4 0.1
Average weekly beer plus cider intake 0.7 1.0 2.1 -1.2 -1.1 1.5 -0.6 -0.3 -1.1 -1.2 -0.9 -0.9 -0.9 -1.2 -1.4 -1.3 -1.2 -0.6 -1.3 -0.8 -0.7 -1.2 -0.4 -1.2 -0.1 0.5 1.0
Irritability 0.5 0.8 2.2 -1.2 0.6 0.2 0.4 -1.2 -1.1 -0.9 0.6 0.1 0.3 -0.7 -0.8 -1.0 0.8 0.2 -1.1 -1.0 -1.0 -1.1 -0.8 -1.0 -1.5 0.2 -1.3
Risk taking 0.7 1.0 4.1 0.9 -0.6 -0.0 -0.8 1.2 -0.1 1.4 -0.4 2.0 0.1 -0.3 0.8 0.5 -0.8 0.6 1.2 -0.1 1.0 0.8 0.6 1.9 1.4 1.8 1.2
Ever had prostate specific antigen (PSA) test 1.0 1.1 4.1 -0.9 1.0 0.6 0.7 -1.8 -0.6 -0.2 0.9 -1.0 0.6 -0.5 -0.7 -1.3 0.2 0.6 -1.2 -1.2 -1.9 -1.1 -2.0 -1.0 -1.5 -0.3 0.3
Fractured/broken bones in last 5 years 1.3 1.7 5.3 -0.3 -0.9 1.9 -1.3 -0.7 -2.1 -0.7 -0.9 -2.0 -0.9 -2.3 -1.0 -1.3 -1.5 -0.6 -0.9 -1.1 -0.8 -1.3 -1.5 -0.7 0.2 0.8 2.3
Age started oral contraceptive pill 0.5 0.6 2.2 0.5 -1.0 -1.5 -1.0 1.1 -0.1 -0.6 -0.9 1.3 -0.6 -0.1 -0.3 -0.1 -0.4 -0.4 0.1 0.4 0.5 0.2 0.9 0.3 1.0 1.4 0.7
Diastolic blood pressure, automated reading 0.0 0.1 0.6 0.0 0.1 0.1 0.1 0.0 -0.1 0.1 0.3 -0.8 0.1 -0.3 0.2 0.4 -0.1 -0.1 0.0 0.3 0.2 0.1 0.1 -0.2 0.0 -0.8 -0.1
Ever depressed for a whole week 0.8 1.0 3.1 -0.7 1.2 -1.1 0.6 -1.7 0.2 0.0 1.0 -0.6 0.4 -0.0 0.1 -0.4 0.5 -0.2 -1.0 -0.8 -1.6 -0.1 -1.7 -1.0 -1.8 -1.5 -1.6
Unable to work because of sickness or disability 0.1 0.1 0.6 -0.6 -0.2 0.8 -0.2 -0.2 0.5 -0.4 -0.2 -0.2 -0.2 0.2 -0.0 0.0 -0.1 -0.3 -0.3 0.1 -0.5 0.1 0.1 -0.6 0.4 -0.4 0.3
Commuting to job workplace: Cycle 1.2 1.4 4.4 -2.1 -1.1 1.6 -1.2 0.1 -1.1 -1.1 -1.5 -0.5 -1.0 -0.6 -1.5 -1.4 -1.5 -0.2 -1.5 -1.7 -0.2 -1.4 -0.9 0.0 -0.4 1.8 1.1
Myopia 1.0 1.4 3.4 1.1 1.7 0.6 1.6 -0.3 1.8 1.6 1.5 -0.2 1.8 1.4 1.3 1.0 1.1 1.8 1.0 1.0 0.1 1.4 -0.5 0.4 -0.5 -0.8 -0.7
Vascular/heart problems diagnosed by doctor 1.6 4.4 11.8 -2.3 -1.7 0.7 -1.9 -0.6 -2.8 -2.8 -1.8 -1.0 -1.9 -2.7 -3.0 -2.7 -3.4 -1.1 -2.7 -2.4 -1.2 -2.8 -0.8 -2.0 -0.2 1.3 2.1
Cholesterol lowering medication 0.8 1.2 4.0 0.1 2.0 -0.1 1.8 -1.2 0.8 0.8 1.8 -0.0 1.5 0.8 1.1 0.5 1.4 1.0 0.0 -0.3 -0.8 0.8 -1.5 -0.0 -1.2 -1.8 -1.2
Medication: Omeprazole (e.g. Zanprol) 0.8 1.0 2.7 1.0 1.1 -1.0 1.2 -0.1 1.0 1.3 1.4 -0.1 1.0 0.8 1.4 1.1 1.6 0.2 0.8 0.4 0.4 0.9 0.1 0.6 0.0 -1.5 -1.5
Pain experienced in last month 1.5 2.6 9.2 -2.7 -0.6 0.8 -1.2 -0.3 -1.1 -2.7 -0.8 -0.1 -0.6 -1.6 -2.3 -2.1 -2.3 0.3 -1.9 -1.9 -0.8 -2.0 -0.8 -1.0 -0.1 1.5 3.0
Supplements: Calcium 0.4 0.4 2.9 0.3 -0.1 1.7 -0.2 0.3 -1.1 -0.2 -0.3 -1.0 -0.4 -1.2 -0.5 -0.4 -0.8 -0.5 -1.0 -0.1 -0.2 -0.6 -0.4 -0.6 0.4 0.0 0.5
Basal cell carcinoma (self-reported) 0.3 0.4 3.0 -0.2 -0.4 1.7 -0.5 0.5 -1.1 0.4 -0.3 -0.5 -0.3 -1.1 -0.0 -0.0 -0.3 0.1 -0.0 0.3 0.3 -0.4 0.1 -0.1 0.5 -0.1 1.0
Heart attack/myocardial infarction (self-reported) 0.6 0.8 2.1 1.4 0.6 0.2 0.5 0.6 1.3 1.2 0.5 0.6 0.6 1.4 1.2 1.0 0.9 0.2 0.9 0.3 0.9 1.3 1.1 0.7 0.5 -0.6 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.4 0.6 2.1 -0.4 1.2 -0.4 1.1 -0.4 0.9 0.3 1.1 -1.4 0.9 0.9 0.7 0.5 0.8 0.4 0.2 0.8 -0.2 0.7 -0.5 -0.1 -0.1 -0.8 -1.1
Heart disease (siblings) 0.4 0.5 4.0 0.8 0.5 -2.0 0.6 0.0 0.7 0.6 0.5 0.2 0.8 0.6 0.5 0.1 0.4 0.9 -0.1 0.2 0.2 0.4 -0.4 0.7 0.7 0.7 1.1
Alcohol drinker status: Previous 0.9 1.0 6.2 -1.1 0.6 -0.1 0.7 -1.5 -0.2 -0.4 0.6 -0.6 -0.0 -0.5 -0.1 -0.4 0.0 -0.6 -0.4 -1.2 -1.4 -0.3 -1.8 -1.4 -1.5 -2.5 -1.1
Pack years of smoking 1.7 2.4 8.9 0.7 0.6 -0.5 0.9 0.4 2.5 2.2 0.7 -0.2 0.3 3.0 2.1 2.0 1.3 -0.8 2.4 1.9 0.7 2.1 0.3 0.9 0.8 -1.7 -2.4
Impedance of whole body 0.2 0.8 1.9 -1.0 0.4 0.0 0.2 -1.3 -1.3 -1.1 0.3 0.1 0.2 -1.3 -0.8 -1.3 -0.8 0.4 -0.7 -1.4 -1.3 -0.5 -0.4 -1.4 -1.2 0.2 0.2
Leg fat mass (left) 0.5 1.9 5.6 1.2 -0.0 -1.5 0.3 1.1 1.0 1.6 0.3 -1.1 -0.1 1.4 1.6 2.1 1.6 -0.7 1.6 2.4 1.7 1.4 0.8 0.7 0.5 -2.2 -2.3
Arm predicted mass (left) 1.6 8.3 19.9 3.1 -0.7 -1.8 -0.5 3.9 2.6 3.6 -0.2 1.6 -0.1 3.1 3.5 4.4 2.2 -0.7 3.6 4.5 4.3 3.3 3.2 3.8 3.4 -0.4 -1.6