Hub : Genes

ZNF667-AS1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1555	0.0475	5.9e-04	0.085	NA	0.024	NA	0.060	3.4e-07	NA	5.2e-03	NA	1.9e-05
2	GTEx	Brain Caudate basal ganglia	0.4280	0.1040	1.4e-04	0.221	NA	0.106	NA	0.174	5.3e-07	NA	5.8e-04	NA	1.0e-05
3	GTEx	Brain Cerebellar Hemisphere	0.5710	0.1040	3.9e-06	0.415	NA	0.213	NA	0.324	7.6e-12	NA	3.6e-06	NA	4.3e-09
4	GTEx	Brain Cerebellum	0.4060	0.0980	2.4e-04	0.278	NA	0.101	NA	0.264	7.7e-09	NA	6.6e-04	NA	2.0e-08
5	GTEx	Cells Transformed fibroblasts	0.1700	0.0440	1.3e-04	0.098	NA	0.096	NA	0.091	8.2e-08	NA	1.2e-07	NA	2.6e-07
6	GTEx	Heart Atrial Appendage	0.3540	0.0760	6.0e-06	0.155	NA	0.069	NA	0.144	1.8e-07	NA	4.9e-04	NA	5.4e-07
7	GTEx	Muscle Skeletal	0.0679	0.0231	1.2e-03	0.072	NA	0.068	NA	0.076	1.4e-07	NA	3.3e-07	NA	6.2e-08
8	GTEx	Skin Sun Exposed Lower leg	0.1850	0.0510	7.2e-05	0.005	NA	0.027	NA	0.027	1.2e-01	NA	2.5e-03	NA	2.5e-03
9	GTEx	Testis	0.5040	0.0670	1.4e-11	0.580	NA	0.567	NA	0.579	5.3e-31	NA	5.6e-30	NA	6.4e-31
10	GTEx	Whole Blood	0.1030	0.0360	2.0e-03	0.029	NA	0.044	NA	0.029	9.5e-04	NA	6.8e-05	NA	1.0e-03
11	METSIM	Adipose	0.0743	0.0220	1.3e-05	0.023	0.047	0.065	0.051	0.051	1.8e-04	1.5e-07	4.6e-10	3.8e-08	3.7e-08

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Bipolar Disorder (2018)	0.9	1.5	3.7	-1.4	0.1	-1.5	-1.4	1.1	1.3	-0.0	-1.3	1.4	-1.9	-0.1
Bipolar Disorder or Schizophrenia	0.9	2.2	5.1	-0.8	2.2	-0.7	-1.2	0.2	0.8	-2.0	-2.3	0.9	-2.1	-1.3
Depressed Affect (Nagel 2018)	0.7	1.6	2.8	-1.6	-1.2	-1.3	-1.6	1.6	1.7	1.1	-0.6	1.5	-0.3	0.1
Depression (Nagel 2018)	0.3	0.5	0.9	-0.7	0.3	-0.7	-0.6	0.9	1.0	-0.2	-0.9	0.8	-0.7	-0.2
Intelligence (Savage-Jansen 2018)	0.8	2.3	5.2	-1.6	-0.8	-1.6	-1.7	2.3	1.9	1.6	0.5	1.6	-1.3	1.2
Neuroticism (Nagel 2018)	0.3	0.7	2.5	-0.8	0.2	-0.5	-1.0	-0.0	0.6	-0.5	-1.6	0.8	-0.7	-1.2
Schizophrenia (2018)	1.0	2.0	7.6	0.1	2.8	0.4	-0.3	-0.7	-0.0	-2.5	-1.9	0.0	-1.2	-1.5
Schizophrenia vs Biploar Disorder	1.8	2.3	4.2	1.8	1.8	2.0	1.7	-1.8	-1.8	-1.2	0.5	-1.7	1.1	-0.1
Worry (Nagel 2018)	0.4	0.9	2.3	-0.6	1.0	-0.3	-0.9	-0.1	0.5	-1.1	-1.3	0.7	-1.4	-1.5
Alzheimer’s Disease (in mother)	0.5	0.6	1.8	0.4	-0.1	0.3	0.4	-1.3	-0.9	-1.1	-1.4	-0.5	0.4	-0.3
Alzheimer’s Disease (in father)	0.1	0.1	0.6	0.1	-0.1	0.2	0.1	0.1	0.1	0.2	-0.6	-0.1	-0.1	0.8
Alzheimer’s Disease (including proxy)	0.5	0.7	1.4	0.8	0.5	0.8	0.7	-1.2	-0.8	-1.1	-1.0	-0.8	0.3	0.7
Crohns Disease (2017)	0.4	0.9	3.2	1.0	-0.7	0.7	1.1	-0.5	-0.9	1.0	0.9	-1.2	1.8	0.4
Irritable Bowel Disease (IBD)	0.2	0.6	2.3	-0.1	-1.5	-0.4	-0.0	0.1	-0.1	1.5	0.8	-0.0	1.0	0.2
Ulcerative Colitis (UC)	0.5	1.0	2.9	-1.0	-1.7	-1.2	-1.1	0.5	0.5	1.5	0.5	1.0	0.2	0.0
Major Depression (MDD)	0.5	0.6	1.1	-1.0	-0.7	-1.0	-1.1	0.7	0.9	0.4	-0.3	0.9	-0.5	-0.6
Reaction Time	0.5	0.9	4.0	-0.8	0.4	-0.8	-1.0	0.3	0.6	-1.0	-1.1	0.9	-2.0	-0.4
Verbal and Numeric Reasoning (VNR)	0.3	0.7	2.5	-0.4	-1.1	-0.6	-0.1	1.3	0.8	1.6	0.6	0.4	-0.3	0.9
Breast Cancer	0.2	0.6	3.6	0.4	0.2	0.4	0.7	-0.7	-0.5	0.2	0.7	-0.3	0.9	1.9
Ovarian Cancer	0.1	0.1	0.5	-0.1	0.0	-0.2	0.3	-0.1	-0.3	0.3	0.7	-0.0	0.4	-0.1
Prostate Cancer	0.1	0.2	0.4	0.3	0.6	0.3	0.3	0.6	0.6	-0.4	0.4	-0.2	-0.2	-0.5
Age at First Birth	0.7	1.0	1.7	-1.0	0.3	-1.1	-1.2	1.3	1.2	0.4	0.3	1.2	-1.2	1.2
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.2	0.3	1.3	-0.1	-0.2	-0.3	-0.1	1.1	0.8	0.7	-0.4	0.0	-0.5	0.4
Coronary Artery Disease (CAD)	1.5	1.8	4.7	1.4	2.2	1.5	1.1	-1.6	-1.3	-1.7	0.2	-1.2	1.0	0.4
Crohns Disease (2012)	0.1	0.2	1.7	0.1	-1.3	-0.1	0.3	-0.4	-0.2	-0.0	-0.2	-0.2	0.5	-0.4
Mean Putamen Volume	0.4	0.4	1.8	0.0	1.3	0.0	-0.1	0.1	0.3	-1.2	-0.6	0.0	-0.8	-0.5
Fasting Glucose	0.3	0.4	1.0	-0.5	-1.0	-0.5	-0.2	0.2	0.8	-0.7	-1.0	0.5	-0.3	-0.8
HbA1C	0.2	0.2	0.5	-0.2	0.7	-0.2	-0.2	0.6	0.4	0.7	-0.3	0.2	-0.4	-0.4
HDL Cholesterol	1.1	1.9	5.2	0.8	-1.8	0.8	1.1	0.1	-0.8	2.2	2.3	-1.0	1.4	1.2
LDL Cholesterol	1.1	1.8	7.0	0.8	1.5	0.9	0.6	-1.9	-1.1	-2.6	-1.7	-0.7	-0.4	-1.0
Lupus	0.3	0.5	1.3	0.9	0.5	1.1	0.7	-0.0	-0.1	0.3	1.0	-0.7	0.7	0.5
Neuroticism (2016)	0.3	0.5	1.3	-0.5	-1.1	-0.5	-0.7	-0.2	0.2	-0.2	-1.1	0.4	-0.3	-1.1
Primary Biliary Cirrhosis	0.3	0.4	1.4	-0.7	0.0	-0.4	-0.7	0.6	1.1	-0.4	-1.2	0.7	-0.6	0.1
Rheumatoid Arthritis	2.8	3.9	11.5	-1.8	-2.1	-1.8	-1.7	2.7	1.9	3.4	1.9	1.7	-0.2	0.5
Schizophrenia (2014)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Triglycerides	0.9	1.5	5.2	-0.7	0.9	-0.7	-1.0	-0.1	0.8	-1.6	-2.3	0.7	-1.5	-1.4
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.2	-0.5	1.5	-0.5	-0.7	0.9	1.2	-0.5	-1.1	0.6	-1.4	-0.2
Ulcerative Colitis	2.1	3.0	5.3	-2.2	-2.3	-2.2	-2.1	1.4	1.7	1.5	0.3	2.2	-1.3	-0.2
Blood Eosinophil Count	0.3	2.0	5.5	-1.6	-0.4	-1.6	-1.7	1.8	1.6	0.5	0.1	1.6	-2.4	0.1
Blood Platelet Count	0.1	1.0	6.8	0.1	1.0	0.4	-0.2	-0.7	0.2	-2.6	-0.4	0.3	-1.4	-0.4
Blood Red Count	0.2	1.8	2.9	1.4	1.7	1.6	1.6	-0.3	-1.1	0.3	0.4	-1.5	1.6	1.6
Blood White Count	0.3	2.0	9.3	0.7	2.3	0.9	0.6	-1.8	-1.0	-3.0	-1.1	-0.6	-0.1	-0.8
Heel T-Score	0.4	3.1	10.9	-1.5	1.9	-1.4	-1.6	1.4	1.9	-1.4	-1.5	1.7	-3.3	-0.6
BMI	0.1	0.5	1.5	-0.3	0.7	-0.5	-0.4	0.5	0.4	-0.4	-1.1	0.2	-1.2	-1.0
Height	0.2	4.6	20.3	-0.4	-1.4	-0.5	-0.2	1.8	0.4	4.5	3.1	0.2	2.6	2.8
Waist Hip Ratio (WHR)	1.2	5.4	19.3	1.1	3.9	1.4	1.0	-2.2	-0.9	-4.4	-3.4	-0.9	-0.8	-1.5
Systolic Blood Pressure	0.6	3.0	4.9	2.0	1.8	2.2	1.8	-1.6	-1.9	-0.7	-0.2	-2.0	1.6	2.0
Smoking Status	0.3	0.7	2.4	0.5	-0.1	0.4	1.0	-1.3	-1.1	-0.4	-0.7	-0.7	1.5	0.1
Allergy or Eczema	0.5	1.3	4.7	-0.9	-2.2	-1.1	-1.1	0.9	1.0	0.1	-1.0	0.8	-1.2	-1.2
Cardiovascular Disease	0.0	0.1	0.2	-0.4	-0.1	-0.4	0.1	0.4	0.2	0.5	-0.1	0.4	-0.1	0.2
Hypothyroidism (self reported)	0.8	1.7	3.7	-1.5	-1.3	-1.3	-1.1	1.9	1.5	1.7	0.7	1.4	-1.1	0.3
Respiratory disease	1.5	3.4	6.2	-1.9	0.3	-2.1	-2.1	0.6	1.6	-1.2	-2.2	2.0	-2.5	-2.5
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.5	0.5	1.2	0.3	0.7	-0.3	-0.3	-0.5	-0.6	-0.5	-0.2	0.3
Lung FEV1/FVC ratio	0.2	0.9	3.9	0.0	-0.2	0.2	0.0	0.6	-0.2	1.5	2.0	0.1	0.5	1.6
Lung FVC	0.3	1.6	4.1	-1.2	-1.3	-1.2	-1.1	1.1	0.7	2.0	1.7	1.2	0.1	1.6
Neuroticism	0.1	0.2	0.5	-0.6	0.4	-0.2	-0.7	0.4	0.5	0.3	-0.2	0.6	-0.5	-0.5
Chronotype (morning person)	0.8	1.8	8.9	-0.7	-0.9	-0.6	-0.3	2.0	0.8	3.0	1.9	0.6	0.4	0.7
Hair Pigment	0.1	3.6	7.0	-2.1	-1.4	-2.3	-2.0	0.9	1.5	-0.8	-2.3	2.0	-2.6	-2.1
Tanning	0.3	3.4	10.7	2.0	0.8	2.0	2.0	-2.0	-2.2	-0.0	0.3	-2.1	3.3	0.7
Hand grip strength (left)	0.3	0.7	3.0	-0.9	-1.7	-0.7	-0.9	-0.5	-0.3	0.7	0.9	0.8	0.8	0.2
Number of treatments/medications taken	0.5	0.9	1.9	-1.3	-0.1	-1.4	-1.4	0.7	0.7	0.9	-0.2	1.2	-1.0	-0.2
Average weekly spirits intake	0.4	0.5	1.5	-0.6	-1.2	-0.6	-0.9	0.6	0.8	0.6	-0.0	0.7	-0.7	0.6
Sensitivity / hurt feelings	0.5	0.8	3.9	-0.2	-0.5	-0.2	-0.4	-0.7	0.1	-1.2	-2.0	0.2	-0.8	-1.2
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.1	-0.6	0.9	-0.6	-0.2	-0.3	0.1	-0.9	-0.9	0.6	-0.3	-1.1
Hearing difficulty/problems: Yes	2.1	3.2	11.0	1.4	3.3	1.6	1.1	-1.9	-1.1	-3.1	-1.6	-1.2	-0.1	-0.7
Relative age of first facial hair	0.7	1.5	2.6	-1.4	-0.9	-1.2	-1.2	1.3	1.1	1.5	1.6	1.4	-0.9	0.1
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	1.1	-0.2	-0.5	-0.3	-0.4	0.2	0.2	0.1	-1.0	0.1	-0.1	-0.4
Ever used hormone-replacement therapy (HRT)	0.7	0.9	1.9	-1.1	-0.7	-1.3	-1.0	0.8	1.0	0.3	-0.8	1.1	-1.4	-0.6
Ever had hysterectomy (womb removed)	0.6	0.7	2.1	-0.8	0.6	-0.8	-0.5	0.1	0.5	-0.9	-0.8	0.8	-1.1	-1.4
Systolic blood pressure, automated reading	0.1	0.2	1.3	0.3	0.4	0.5	0.1	-0.3	-0.5	0.4	0.2	-0.3	0.1	1.2
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.6	0.2	0.6	0.2	0.1	0.7	-0.1	1.3	1.3	-0.2	0.5	0.7
Angina	0.5	0.7	3.5	0.2	-1.9	0.1	0.2	-0.4	-0.5	1.0	-0.2	-0.3	0.8	1.3
Medication for hormone replacement therapy	0.3	0.3	0.9	0.5	0.0	0.3	0.3	-0.6	-0.3	-0.7	-1.0	-0.5	-0.1	-0.9
Vitamin and mineral supplements	2.0	2.7	4.3	2.0	1.0	1.7	1.9	-2.0	-2.0	-1.2	-0.1	-2.1	2.0	-0.1
Supplements: Zinc	0.7	0.8	1.5	-1.0	-0.3	-1.1	-0.8	1.1	0.9	1.2	0.9	1.0	-0.4	0.1
Medication: Co-codamol	0.5	0.6	2.9	-0.5	0.2	-0.5	-0.5	-0.1	0.2	-0.9	-1.2	0.5	-0.9	-1.7
Medication: Metformin	0.3	0.5	1.9	0.6	1.4	0.6	0.7	-0.5	-0.3	-0.9	-0.6	-0.6	-0.5	0.3
Diabetes (father)	1.0	1.3	3.0	1.2	1.5	1.2	1.4	-0.8	-0.9	-0.3	0.9	-1.1	0.6	1.7
Diabetes (mother)	1.7	2.1	4.8	1.1	1.2	0.9	1.3	-1.7	-1.0	-2.1	-2.2	-1.2	0.1	-1.9
Severe depression (siblings)	1.5	1.7	3.2	-1.6	-0.2	-1.7	-1.7	1.7	1.8	0.9	0.0	1.6	-0.8	0.3
Pack years adult smoking proportion	0.5	0.8	1.4	-1.2	-1.2	-1.0	-1.0	0.7	0.9	0.6	0.1	1.0	0.4	-1.0
Impedance of leg (right)	0.0	0.2	0.5	0.6	0.7	0.6	0.4	-0.4	-0.4	-0.7	0.0	-0.5	-0.1	0.2
Leg fat-free mass (left)	0.3	1.5	7.8	-0.6	-1.4	-0.9	-0.4	1.2	0.5	2.8	1.2	0.3	1.5	0.4
Trunk fat percentage	0.4	1.6	2.7	-1.2	-0.0	-1.4	-1.3	1.6	1.6	0.7	-1.5	1.1	-1.2	-1.2
Hand grip strength (right)	0.4	1.1	3.3	-1.1	-1.8	-0.9	-1.1	0.1	0.1	1.4	1.2	1.0	0.9	0.4
Townsend deprivation index at recruitment	0.3	0.4	1.6	0.1	1.3	0.1	0.1	-0.9	-0.7	-0.7	0.1	-0.0	-0.0	-0.7
Current tobacco smoking	0.3	0.5	2.1	-0.4	-0.1	-0.5	-0.1	-0.9	-0.4	-0.6	-1.1	0.3	0.5	-1.4
Average weekly fortified wine intake	1.1	1.3	2.5	-0.9	-0.9	-0.9	-1.1	1.5	1.1	1.6	0.3	0.9	-1.5	1.0
Maternal smoking around birth	0.4	0.5	1.6	-1.0	-1.3	-1.0	-0.8	-0.3	-0.0	0.6	-0.0	0.9	0.2	-0.1
Fed-up feelings	1.5	2.8	4.8	-2.2	-1.6	-2.1	-2.1	1.3	1.8	0.4	-1.2	2.0	-0.6	-1.9
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	0.5	-0.7	0.4	-0.7	-0.6	0.2	0.4	-0.1	-0.6	0.7	-0.2	-0.2
Relative age voice broke	0.4	0.7	3.1	-0.2	0.9	-0.1	-0.2	1.2	0.9	0.7	1.8	0.4	-0.4	0.1
Taking other prescription medications	1.6	2.4	5.1	-1.7	-0.7	-1.8	-1.7	1.5	1.7	0.5	-1.6	1.6	-2.2	-1.2
Age when periods started (menarche)	0.1	0.3	1.3	0.1	1.1	0.4	0.0	-0.8	-0.6	-0.9	0.1	-0.0	0.2	0.0
Bilateral oophorectomy (both ovaries removed)	0.7	0.8	2.6	0.1	1.3	-0.1	0.3	-0.8	-0.3	-1.5	-0.6	-0.1	-0.7	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.7	4.6	-1.2	-0.0	-1.0	-1.3	1.9	1.8	0.5	0.3	1.3	-2.1	0.8
Tinnitus: Yes, but not now, but have in the past	2.5	2.7	5.0	-1.9	1.3	-1.6	-2.2	1.2	1.8	-0.8	-1.3	2.0	-1.9	-1.2
Qualifications: CSEs or equivalent	0.4	0.5	1.4	0.4	1.2	0.5	0.4	-0.9	-0.7	-0.9	0.7	-0.3	0.4	-1.0
Serious illness, injury or assault to yourself	0.7	0.8	4.7	-0.2	0.2	-0.5	-0.5	-0.7	0.2	-1.5	-2.2	0.3	-0.6	-0.6
High blood pressure	0.6	1.5	2.6	1.3	1.3	1.3	1.5	-0.6	-1.3	0.6	0.9	-1.4	1.4	1.6
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.4	-0.4	-0.7	-0.5	-0.7	0.5	0.7	-0.5	-1.2	0.4	-1.1	-1.1
Multivitamins +/- minerals	1.8	2.3	5.4	-1.5	-1.8	-1.2	-1.2	1.9	1.5	2.3	1.4	1.5	-0.7	1.2
Stomach or abdominal pain in last month	0.2	0.2	1.5	-0.0	-1.2	-0.4	0.4	-0.3	-0.5	0.6	0.2	-0.1	0.2	0.1
Supplements: Glucosamine	0.8	1.1	3.3	-1.0	-0.5	-1.0	-0.8	1.0	0.5	1.8	1.5	1.0	0.1	1.0
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	2.8	0.1	-1.7	0.0	0.1	0.1	-0.4	1.4	0.0	-0.4	1.3	0.4
Medication: Atenolol	0.6	0.8	1.6	-1.3	-0.5	-1.2	-1.1	0.8	0.8	0.5	-0.3	1.2	-0.8	-0.6
Medication: Levothyroxine sodium	0.9	1.6	5.1	-1.0	-1.7	-1.0	-0.7	1.8	1.0	2.3	1.3	0.9	-0.3	0.3
Sitting height	0.8	6.0	26.4	-0.2	-2.1	-0.4	0.1	1.6	-0.2	5.1	3.7	-0.1	3.3	2.6
Chronic bronchitis/emphysema (father)	0.6	0.7	1.6	1.0	1.0	0.8	1.2	-0.8	-0.4	-1.1	-0.5	-1.0	-0.1	-0.6
High blood pressure (mother)	0.1	0.1	0.5	-0.4	-0.3	-0.2	-0.3	0.3	0.3	0.2	-0.7	0.3	-0.3	0.6
Body mass index (BMI)	0.1	0.6	0.9	-0.8	-0.4	-1.0	-0.7	0.9	0.8	0.7	-1.0	0.6	-0.8	-0.8
Impedance of leg (left)	0.0	0.1	0.4	0.5	0.3	0.6	0.3	-0.1	-0.2	-0.2	0.5	-0.3	0.1	0.4
Leg predicted mass (left)	0.3	1.6	8.0	-0.7	-1.4	-1.0	-0.4	1.3	0.5	2.8	1.2	0.4	1.4	0.4
Trunk fat mass	0.3	1.1	2.6	-1.1	-0.6	-1.3	-1.0	1.6	1.3	1.6	-0.7	0.8	-0.3	-0.7
Waist circumference	0.3	1.0	3.5	-0.5	1.1	-0.7	-0.5	0.7	0.9	-0.5	-1.9	0.4	-1.0	-1.6
Number of incorrect matches in round	0.1	0.1	0.3	-0.0	0.2	0.2	-0.5	0.4	0.3	0.2	0.6	0.1	-0.5	0.3
Past tobacco smoking	0.2	0.4	1.1	0.1	1.0	0.3	-0.3	1.1	0.7	0.1	0.6	0.1	-1.1	0.0
Alcohol usually taken with meals	0.8	1.3	3.2	1.0	-0.0	0.8	1.2	-0.9	-1.5	0.8	1.1	-1.2	1.8	1.1
Nervous feelings	0.5	0.9	3.5	0.6	1.9	0.9	0.3	-1.2	-0.7	-1.5	-0.6	-0.4	-0.2	-0.5
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.5	4.6	0.5	0.8	0.7	0.2	-2.1	-1.1	-2.1	-1.6	-0.5	0.2	-1.4
Hearing difficulty/problems with background noise	2.2	3.5	15.1	0.7	2.2	1.0	0.5	-2.3	-0.8	-3.9	-2.4	-0.6	-0.4	-2.1
Hair/balding pattern: Pattern 2	0.4	0.5	1.1	0.4	0.8	0.3	0.5	-0.9	-0.8	-0.9	-0.3	-0.5	0.7	-1.0
Had menopause	0.1	0.1	0.4	-0.3	-0.6	-0.4	-0.1	0.0	0.1	0.4	-0.1	0.2	-0.2	0.3
Had other major operations	0.2	0.2	1.0	-0.3	-0.6	-0.4	-0.1	-0.5	0.1	-0.0	-0.8	0.2	0.0	-1.0
Forced vital capacity (FVC)	0.5	1.9	6.8	-0.3	-1.0	-0.4	-0.5	0.9	0.0	2.6	2.4	0.2	1.5	1.9
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	4.2	0.0	0.7	0.3	-0.2	1.0	0.7	0.5	1.0	0.2	-0.9	2.0
Ever unenthusiastic/disinterested for a whole week	0.6	0.7	1.3	-0.8	1.2	-0.7	-0.7	-0.2	0.6	-1.1	-0.9	0.9	-0.5	-1.0
Qualifications: None of the above	0.8	1.7	4.9	-1.0	0.9	-0.9	-1.0	0.2	1.0	-1.5	-2.2	1.1	-1.6	-1.8
Financial difficulties in last 2 years	0.3	0.4	1.6	0.1	-1.3	-0.1	0.5	-0.1	-0.5	1.0	0.4	-0.2	0.9	0.2
Mouth/teeth dental problems	1.7	2.6	11.7	1.2	0.4	1.2	1.1	1.4	0.0	2.2	1.8	-1.2	0.9	3.4
Heart attack	0.2	0.3	1.8	0.4	-0.5	0.2	0.3	-0.1	-0.2	0.5	-0.6	-0.5	0.3	1.3
Allergy	0.5	1.2	3.0	0.9	0.7	1.0	1.2	-0.7	-1.1	0.5	1.7	-0.8	1.4	1.5
Pain all over the body in last month	1.5	1.6	2.9	-1.6	-1.0	-1.6	-1.7	1.2	1.7	0.5	-1.2	1.5	-1.0	-0.2
Diabetes (self-reported)	0.4	0.6	2.1	0.6	1.4	0.5	0.8	-0.6	-0.4	-0.7	-1.1	-0.6	-0.1	0.4
Hayfever/allergic rhinitis (self-reported)	1.0	1.3	3.1	-1.0	0.2	-1.1	-1.3	0.4	0.9	-0.8	-1.3	1.0	-1.7	-1.8
Medication: Ramipril	3.1	4.0	7.1	2.3	0.8	2.3	2.7	-2.6	-2.6	-1.3	-1.2	-2.5	1.5	-0.2
Medication: Simvastatin	0.5	0.8	2.4	0.7	1.5	0.9	0.8	-0.4	-0.1	-1.5	-1.2	-0.6	-0.5	-0.2
Fluid intelligence score	0.4	0.7	3.3	-0.6	-1.8	-0.9	-0.2	1.0	0.8	1.3	-0.3	0.5	-0.1	0.0
Illnesses of siblings	0.6	0.8	1.5	1.0	1.2	1.0	1.0	-1.1	-1.2	-0.5	0.4	-0.9	0.7	0.2
Neuroticism score	0.4	0.7	1.6	-0.8	0.9	-0.5	-1.1	-0.1	0.6	-1.0	-1.1	0.9	-0.7	-1.2
Weight	0.3	1.3	6.7	-0.9	-1.2	-1.1	-0.7	1.5	0.9	2.6	0.4	0.6	0.6	0.1
Impedance of arm (right)	0.4	1.7	8.0	0.7	2.8	0.6	0.4	-0.6	-0.1	-2.3	-1.8	-0.5	-0.8	-0.3
Arm fat percentage (right)	0.2	0.8	3.5	-0.3	1.0	-0.5	-0.4	0.7	0.9	-0.4	-1.9	0.2	-1.1	-1.1
Trunk fat-free mass	0.7	4.3	18.1	-0.1	-2.5	-0.4	0.2	1.3	-0.1	4.3	3.1	-0.2	2.8	1.9
Hip circumference	0.4	1.7	4.4	-1.2	-0.7	-1.5	-1.2	2.1	1.6	1.9	-0.2	1.0	-0.7	-1.0
Time employed in main current job	1.8	2.1	4.3	1.7	1.9	1.8	2.1	-1.1	-1.2	-1.1	0.8	-1.6	1.0	-0.9
Alcohol intake versus 10 years previously	0.7	1.1	2.4	-1.4	-1.5	-1.1	-1.6	0.7	1.1	0.2	-0.2	1.3	-0.0	-0.9
Father’s age at death	0.7	0.9	1.8	-1.0	-0.6	-1.2	-1.3	1.2	1.3	0.2	-0.4	1.1	-1.2	-0.3
Worrier / anxious feelings	0.4	0.7	2.4	0.2	1.0	0.3	-0.2	-1.0	-0.4	-1.5	-1.1	-0.0	-0.8	-1.1
Frequency of tiredness / lethargy in last 2 weeks	0.3	0.5	2.3	-0.5	0.7	-0.4	-0.6	-0.4	0.0	-0.8	-1.5	0.4	-0.6	-0.8
Falls in the last year	1.0	1.3	3.7	-0.4	1.4	-0.2	-0.6	-1.0	-0.2	-1.9	-1.7	0.4	-1.0	-1.8
Hair/balding pattern: Pattern 3	0.6	0.9	2.0	1.4	0.1	1.4	1.1	-0.9	-1.2	-0.1	0.2	-1.4	0.4	0.8
Number of live births	0.3	0.4	1.7	-0.4	1.3	-0.2	-0.4	0.5	0.6	-0.1	1.0	0.5	-0.1	-0.4
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	7.1	-0.3	-0.8	-0.2	-0.5	0.8	-0.2	2.6	2.7	0.2	1.8	1.9
Pulse rate	0.1	0.2	0.6	0.1	0.2	0.2	0.2	0.8	0.3	0.4	0.4	-0.0	-0.6	-0.6
Happiness	0.8	1.0	1.5	-1.2	-1.1	-1.2	-0.9	1.2	1.0	1.2	-0.5	1.1	-1.0	0.1
Noisy workplace	2.2	2.7	4.5	-1.7	-2.0	-1.7	-2.1	0.7	1.6	-0.9	-1.6	1.8	-1.9	-1.5
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.4	-1.0	-1.6	-1.0	-1.0	-0.3	0.4	-0.4	-0.0	1.0	-0.5	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	1.6	0.1	-1.3	-0.0	0.2	-1.2	-0.8	-0.2	-0.1	-0.3	1.1	-0.9
Mouth/teeth dental problems: Dentures	2.3	3.8	10.4	-2.0	-0.6	-2.1	-1.6	-0.3	1.2	-1.6	-2.9	1.9	-2.0	-3.2
Asthma	0.8	1.6	4.2	-0.6	1.5	-0.8	-0.7	0.9	1.3	-1.0	-1.8	0.6	-2.1	-1.7
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	2.7	-0.5	1.6	-0.6	-0.7	1.2	1.1	0.0	-0.1	0.6	-0.5	-0.2
Medication: Cholesterol lowering	0.3	0.4	2.1	0.2	0.4	0.4	0.4	-0.4	0.0	-1.2	-1.4	-0.2	-0.3	0.1
Depression (self-reported)	1.0	1.1	2.2	-1.3	1.0	-1.1	-1.4	0.8	1.3	-0.5	-0.4	1.5	-1.4	0.1
Medication: Lansoprazole	0.3	0.3	1.4	-0.2	-0.3	-0.3	-0.3	-0.6	-0.2	-0.8	-0.9	0.2	-0.6	-1.2
Prospective memory result	0.6	0.7	1.7	-1.0	-1.1	-0.8	-0.7	1.0	0.9	0.5	-0.1	1.0	-1.3	-0.0
Lung cancer (father)	0.5	0.6	2.2	-0.5	-0.0	-0.4	-0.6	0.3	0.6	-1.0	-1.5	0.6	-1.1	-0.8
Illnesses of mother	0.5	0.6	1.9	-0.1	1.1	-0.1	-0.1	0.2	0.7	-1.4	-0.9	0.2	-0.8	-1.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	4.3	-0.1	-0.2	-0.2	-0.5	0.6	-0.2	1.9	2.1	0.1	1.3	1.7
Pulse wave Arterial Stiffness index	0.7	0.8	2.1	-0.8	-0.7	-0.9	-0.8	1.2	0.8	1.4	0.6	0.7	-0.2	1.2
Impedance of arm (left)	0.3	1.4	4.4	-0.0	1.9	0.0	-0.3	-0.1	0.6	-2.1	-2.0	0.1	-1.2	-1.0
Arm fat mass (right)	0.2	1.0	2.2	-1.0	-0.1	-1.3	-1.0	1.5	1.3	1.1	-0.9	0.8	-0.7	-0.9
Trunk predicted mass	0.7	4.2	17.6	-0.2	-2.6	-0.4	0.2	1.3	-0.0	4.2	3.0	-0.1	2.7	1.8
Standing height	0.5	5.4	23.1	-0.4	-2.3	-0.6	-0.1	1.8	0.3	4.8	3.4	0.1	3.2	2.3
Length of working week for main job	0.6	0.7	3.0	0.4	0.0	0.4	0.3	-0.1	-0.7	1.1	1.2	-0.5	1.7	0.7
Exposure to tobacco smoke at home	0.3	0.3	0.9	-0.6	0.9	-0.6	-0.5	0.5	0.6	0.0	-0.6	0.7	-0.3	0.4
Breastfed as a baby	0.4	0.4	1.3	-0.6	0.4	-0.6	-0.5	0.6	0.8	-0.3	-0.9	0.6	-1.2	-0.5
Tense / ‘highly strung’	1.9	3.1	5.3	2.0	2.1	2.1	1.9	-2.3	-2.1	-1.3	0.1	-1.9	1.5	-0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.4	1.5	-0.2	1.2	-0.1	-0.1	0.1	0.6	-0.7	-0.5	0.3	-0.4	-1.2
Hair/balding pattern: Pattern 4	0.5	1.3	3.0	-1.0	-0.2	-1.0	-1.3	0.4	1.1	-1.2	-1.7	1.1	-1.6	-1.0
Birth weight of first child	1.3	2.4	5.3	1.3	-1.4	1.2	1.5	-0.4	-1.3	1.7	2.0	-1.5	2.3	1.4
Peak expiratory flow (PEF)	0.2	0.5	2.6	-0.4	-0.2	-0.3	-0.5	0.6	0.1	1.6	1.3	0.3	0.6	0.6
Pulse wave reflection index	0.2	0.2	1.4	-0.2	0.5	-0.2	-0.5	0.0	0.2	-0.1	-0.3	0.3	-0.1	1.2
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.3	-0.4	0.3	-0.5	-0.1	-0.3	0.0	-0.3	0.2	0.4	0.2	0.2
Loud music exposure frequency	0.8	0.9	4.4	0.1	0.4	0.1	0.1	-1.4	-0.6	-2.1	-1.0	0.0	-0.3	-1.2
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	2.8	-0.1	-1.7	-0.1	-0.5	-0.6	-0.6	0.1	0.8	0.1	0.5	0.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	3.6	-0.1	-0.0	-0.0	-0.1	-0.7	-0.2	-1.4	-0.9	0.1	-0.1	-1.9
Blood clot in the leg (DVT)	0.0	0.0	0.1	-0.2	0.1	-0.1	-0.4	-0.2	-0.0	-0.3	-0.1	0.2	-0.1	0.1
Medication: Paracetamol	0.5	0.8	2.0	-1.1	-1.4	-1.1	-0.8	0.5	0.7	0.8	-0.3	0.9	0.3	-1.0
Headache pain in last month	1.4	2.5	3.7	-1.8	-1.9	-1.9	-1.6	1.4	1.7	0.2	-1.0	1.6	-1.2	-1.9
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	1.8	-0.8	-1.2	-1.0	-1.0	1.0	0.7	1.3	1.3	0.8	-0.5	-0.1
Glaucoma (self-reported)	0.8	1.0	3.4	1.1	1.8	1.1	0.9	-0.8	-1.1	-0.3	1.0	-1.0	0.4	0.2
Gout (self-reported)	0.3	0.4	2.1	-0.0	0.8	-0.0	-0.1	-0.8	-0.3	-1.5	-1.0	0.2	-0.1	0.4
Hypothyroidism/myxoedema (self-reported)	0.7	1.3	2.9	-1.3	-1.1	-1.2	-0.9	1.7	1.2	1.7	0.7	1.2	-0.8	0.2
Medication: Amlodipine	0.6	0.9	2.1	1.3	-0.2	1.0	1.4	-0.8	-1.3	0.1	-0.2	-1.4	0.6	0.5
Medication: Ventolin 100micrograms inhaler	0.0	0.1	0.2	-0.2	-0.2	-0.3	-0.2	-0.1	-0.1	0.3	0.1	0.2	0.1	-0.5
Birth weight	0.9	2.0	7.2	-0.1	-1.6	-0.1	-0.0	1.3	0.4	2.7	2.2	-0.0	1.7	1.6
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.5	-0.2	0.0	-0.3	-0.1	0.1	0.3	0.3	0.1	0.2	-0.2	-0.7
High blood pressure (siblings)	0.1	0.1	0.3	-0.1	-0.5	0.0	-0.2	0.0	0.0	0.0	-0.6	0.0	0.1	-0.4
Forced vital capacity (FVC), Best measure	0.3	1.0	3.0	-0.6	-0.4	-0.7	-1.0	0.8	0.3	1.7	1.7	0.6	0.9	1.2
Body fat percentage	0.3	1.1	2.0	-0.9	0.1	-1.2	-0.9	1.4	1.4	0.6	-1.4	0.8	-1.1	-1.0
Leg fat percentage (right)	0.1	0.3	0.9	-0.4	-0.1	-0.6	-0.3	0.6	0.5	0.5	-1.0	0.2	-0.7	-0.7
Arm fat-free mass (right)	0.7	3.7	17.3	-0.8	-2.5	-1.0	-0.4	1.8	0.6	4.2	2.6	0.5	2.0	1.2
Exposure to tobacco smoke outside home	0.5	0.7	3.7	-0.7	-1.9	-0.7	-0.6	0.4	0.2	1.2	0.5	0.5	0.5	0.2
Comparative body size at age 10	0.2	0.6	2.5	0.5	-1.6	0.5	0.2	-0.9	-1.0	-0.0	-0.3	-0.5	0.7	0.7
Number of full brothers	0.1	0.1	0.5	0.2	0.3	0.3	0.3	0.2	-0.2	0.6	0.1	-0.3	0.7	0.2
Worry too long after embarrassment	0.5	0.8	1.5	1.1	1.2	1.1	0.9	-1.0	-1.1	-0.6	0.2	-1.0	0.2	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.2	0.3	1.2	0.2	0.2	0.2	0.3	-1.1	-0.6	-0.8	-0.4	-0.2	0.5	-0.3
Wheeze or whistling in the chest in last year	1.1	2.0	7.7	-1.1	0.6	-1.4	-1.0	0.8	1.3	-1.0	-1.6	1.0	-1.6	-2.8
Number of children fathered	0.7	0.8	3.1	-0.3	-0.2	-0.3	-0.6	0.5	-0.1	1.8	1.7	0.3	0.9	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.3	1.9	-0.0	-1.4	0.4	-0.0	-0.5	-0.4	0.1	0.1	-0.0	-0.1	0.8
Age at first live birth	0.1	0.2	0.5	-0.2	-0.7	-0.2	-0.5	-0.0	0.3	-0.5	-0.3	0.4	-0.6	0.4
Pulse wave peak to peak time	0.6	0.7	1.2	0.8	0.4	0.9	0.9	-1.1	-0.9	-1.0	-0.3	-0.8	0.5	-1.1
Health satisfaction	0.5	0.6	1.3	-0.9	1.2	-0.9	-1.0	0.5	0.5	0.1	-0.3	0.9	-0.9	-1.0
Shortness of breath walking on level ground	0.6	0.7	1.3	0.7	1.1	0.9	0.6	-1.1	-1.1	-1.1	-0.8	-0.8	0.4	-0.1
Qualifications: College or University degree	0.1	0.4	2.0	0.5	-1.4	0.4	0.3	-0.5	-0.2	-0.8	-0.5	-0.5	-0.1	0.1
Eye problems/disorders: None of the above	0.4	0.5	1.0	-0.9	-0.9	-0.7	-1.0	0.4	0.8	0.2	-0.4	0.9	-0.6	0.6
Mouth/teeth dental problems: Loose teeth	0.8	0.9	2.3	-1.3	-0.1	-1.2	-1.5	0.6	0.8	-0.0	0.0	1.4	-1.4	-0.4
Emphysema/chronic bronchitis	1.3	1.5	4.0	1.0	-0.3	1.1	1.2	-2.0	-1.4	-1.0	-0.6	-1.2	1.6	-1.1
Medication for pain relief, constipation, heartburn	0.3	0.5	0.7	0.8	-0.1	0.8	0.6	-0.8	-0.7	-0.6	0.4	-0.8	0.7	0.8
Neck or shoulder pain in last month	0.9	1.3	4.2	-1.1	-2.0	-1.2	-0.7	1.5	1.4	1.3	0.2	0.9	-0.1	-0.6
Medication: Blood pressure	0.8	1.4	2.3	1.4	1.4	1.5	1.4	-0.9	-1.1	-0.8	-0.4	-1.4	1.0	1.3
Angina (self-reported)	0.6	0.8	2.9	0.4	-1.7	0.4	0.4	-0.6	-0.7	0.8	-0.2	-0.6	1.0	1.4
Migraine (self-reported)	0.2	0.2	0.4	-0.5	-0.2	-0.4	-0.5	0.6	0.7	0.6	0.3	0.5	-0.1	0.4
Medication: Ibuprofen	0.3	0.4	2.5	-0.3	1.6	-0.4	-0.5	0.5	0.6	-0.3	-0.3	0.4	-0.4	-0.3
Medication: Allopurinol	0.5	0.6	1.2	-0.9	0.3	-0.9	-0.8	0.8	0.9	-0.1	-0.0	1.1	-0.8	0.9
Medication: Omeprazole	0.6	0.7	3.9	-0.3	-0.1	-0.6	-0.2	-0.5	-0.2	-0.4	-1.7	0.1	-0.5	-2.0
Medication: Seretide 50 evohaler	0.3	0.3	1.0	0.8	-1.0	0.6	0.5	0.0	-0.3	0.6	0.2	-0.8	0.1	0.5
Mean time to correctly identify matches	0.2	0.4	1.7	-0.2	0.4	-0.1	-0.3	-0.3	-0.2	-1.1	-0.9	0.2	-1.3	-0.3
Heart disease (mother)	0.5	0.6	2.8	0.1	-0.7	-0.0	0.1	0.1	-0.3	1.2	1.7	-0.2	0.3	1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	1.3	0.3	-1.1	0.1	0.6	-0.1	-0.2	0.2	-0.7	-0.4	0.1	-0.1
Whole body fat mass	0.4	1.6	3.2	-1.3	-0.8	-1.6	-1.2	1.8	1.5	1.6	-0.8	1.1	-0.7	-0.9
Leg fat mass (right)	0.2	0.8	2.6	-0.8	-0.7	-1.1	-0.6	1.3	0.9	1.6	-0.4	0.6	-0.2	-0.7
Arm predicted mass (right)	0.9	4.6	21.3	-0.8	-2.8	-1.0	-0.4	1.9	0.5	4.6	3.0	0.6	2.2	1.5
Pulse rate, automated reading	0.3	1.1	4.7	-0.7	0.2	-0.8	-0.6	1.1	1.1	-0.4	-0.8	0.7	-1.4	-2.2
Alcohol intake frequency.	0.9	2.2	3.0	1.6	1.1	1.6	1.6	-1.7	-1.6	-1.3	-0.7	-1.7	1.3	-1.4
Comparative height size at age 10	0.1	0.6	3.0	0.3	-1.1	0.0	0.6	-0.3	-0.7	1.0	-0.7	-0.6	1.7	0.1
Number of full sisters	1.4	1.7	3.6	-1.8	-0.5	-1.9	-1.5	1.2	1.8	0.1	-0.3	1.8	-1.2	-0.1
Suffer from ‘nerves’	2.4	3.8	6.4	-2.3	0.3	-2.1	-2.4	1.2	2.3	-1.2	-1.7	2.4	-2.5	-2.0
Overall health rating	0.2	0.4	1.8	0.1	1.3	-0.1	0.3	0.1	-0.3	1.0	0.0	-0.2	0.2	1.4
Chest pain or discomfort	0.1	0.1	0.6	0.2	-0.7	0.0	0.3	0.2	-0.0	0.3	-0.8	-0.3	0.0	0.2
Had major operations	1.6	1.8	4.0	1.2	2.0	1.1	1.1	-1.9	-1.7	-1.3	-0.3	-1.2	1.3	-0.4
Age at last live birth	0.3	0.4	0.9	-0.4	0.8	-0.1	-0.9	0.3	0.7	-1.0	0.1	0.6	-0.2	-0.6
Family relationship satisfaction	0.3	0.4	0.9	-0.7	-0.6	-0.7	-0.2	0.6	0.4	1.0	-0.2	0.7	-0.7	-0.1
Leg pain on walking	1.2	1.5	2.7	1.4	1.3	1.3	1.4	-1.1	-1.4	-0.3	0.8	-1.4	1.6	0.9
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	1.8	0.9	1.1	1.0	0.8	-0.9	-1.0	-0.4	1.2	-0.8	1.3	-0.1
Commuting to job workplace: Car/motor vehicle	1.0	1.1	3.1	-0.6	-0.6	-0.7	-0.4	1.8	1.4	1.5	0.0	0.7	-0.8	1.6
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.0	0.1	0.3	0.1	-0.2	1.0	0.7	0.4	0.4	0.0	-0.9	0.2
Medication: Aspirin	0.3	0.4	1.1	0.7	0.9	0.9	0.6	-0.2	-0.2	-0.1	-0.2	-0.7	-0.0	1.0
Supplements: Vitamin C	0.3	0.3	0.9	-0.1	0.9	-0.1	-0.1	-0.0	0.2	-0.8	-1.0	0.2	-0.9	-0.6
Knee pain experienced in last month	1.3	2.1	3.8	1.6	0.6	1.4	1.7	-1.9	-1.5	-1.4	-0.5	-1.7	1.6	-1.3
Hypertension (Self-reported)	0.7	2.0	3.1	1.5	1.3	1.5	1.8	-0.8	-1.6	0.5	0.9	-1.6	1.7	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	1.3	0.1	-0.8	-0.0	0.2	-0.3	-0.1	-0.2	-1.2	-0.2	-0.3	1.1
Illnesses of father: Heart disease	0.2	0.3	0.7	-0.3	-0.5	-0.2	-0.2	-0.8	-0.5	-0.1	0.5	0.3	0.7	0.8
Illnesses of siblings: Diabetes	1.7	2.1	4.2	-1.5	-0.7	-1.4	-1.7	1.2	1.8	-0.5	-1.7	1.6	-2.0	-1.0
Smoking status: Previous	0.3	0.4	1.2	0.3	-1.1	0.0	0.6	-0.7	-0.6	0.3	-0.0	-0.4	1.1	0.8
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.5	7.3	1.3	0.2	1.0	1.5	-0.4	-1.2	1.6	1.9	-1.4	2.7	2.3
Whole body fat-free mass	0.6	3.4	16.0	-0.4	-2.3	-0.7	-0.1	1.4	0.2	4.0	2.6	0.1	2.3	1.3
Leg fat-free mass (right)	0.3	1.8	9.1	-0.6	-1.5	-0.8	-0.3	1.2	0.4	3.0	1.5	0.3	1.7	0.6
Arm fat percentage (left)	0.4	1.4	4.6	-0.9	0.6	-1.0	-0.9	1.0	1.4	-0.4	-2.1	0.7	-1.5	-1.5
Average weekly red wine intake	0.4	0.6	1.9	0.6	-0.3	0.6	0.5	-0.9	-1.4	0.4	1.2	-0.6	0.8	0.7
Handedness (chirality/laterality): Left-handed	1.6	1.9	4.2	-1.5	-0.8	-1.6	-1.6	0.2	0.8	-0.9	-2.0	1.5	-1.6	-1.7
Mood swings	0.5	0.9	2.6	0.8	1.3	1.1	0.5	-1.2	-1.1	-0.1	0.5	-0.8	1.6	0.6
Loneliness, isolation	1.4	2.0	4.1	-1.9	-0.4	-1.6	-2.0	1.6	1.7	1.0	0.0	1.9	-0.7	0.0
Long-standing illness, disability or infirmity	0.2	0.3	1.0	0.3	1.0	0.2	0.2	-0.4	-0.2	-0.7	-0.9	-0.3	-0.1	-0.8
Ever had bowel cancer screening	0.4	0.4	1.2	-0.7	-0.0	-0.9	-0.7	0.5	0.6	0.1	-0.5	0.7	-1.1	-0.8
Diabetes diagnosed by doctor	0.3	0.6	2.0	0.7	1.4	0.6	1.0	-0.5	-0.4	-0.7	-0.9	-0.8	-0.0	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	1.4	0.0	-0.1	0.3	0.2	-0.1	-0.4	0.9	0.9	-0.1	1.2	-0.0
Friendships satisfaction	0.2	0.3	1.2	-0.6	0.3	-0.5	-0.5	0.2	-0.1	0.7	0.1	0.6	-0.4	1.1
Qualifications: nursing, teaching	1.0	1.5	5.1	-0.8	-1.7	-1.0	-0.9	1.2	0.6	2.3	1.5	0.7	0.1	1.2
Commuting to job workplace: Walk	1.2	1.3	3.1	1.1	1.2	1.2	0.8	-1.8	-1.5	-1.1	-0.1	-1.1	1.0	-0.4
Eye problems/disorders: Cataract	0.3	0.3	1.0	0.5	0.2	0.3	0.8	-0.4	-0.3	-0.7	-0.3	-0.6	0.5	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	0.9	0.3	-0.5	0.3	0.3	-0.8	-1.0	0.2	0.7	-0.4	0.8	-0.1
Medication for cholesterol	0.3	0.5	3.3	-0.0	-0.1	-0.1	0.0	0.6	0.2	1.0	1.8	0.1	0.8	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	1.5	-0.8	-0.2	-0.7	-1.1	0.6	0.8	-0.3	-0.7	0.9	-1.2	0.1
Back pain experienced in last month	0.2	0.2	0.5	-0.6	-0.6	-0.7	-0.4	0.5	0.5	0.1	-0.4	0.5	-0.2	-0.6
Mineral and other dietary supplements	0.5	0.7	1.2	1.0	0.9	0.8	1.1	-0.6	-0.6	-1.0	-0.8	-1.0	0.6	-0.3
Breast cancer (self-reported)	0.8	1.0	3.4	1.0	0.6	0.8	0.6	-1.9	-1.5	-1.1	0.5	-0.9	0.8	-0.2
Asthma (self-reported)	0.8	1.6	3.9	-0.5	1.5	-0.7	-0.7	0.7	1.2	-1.2	-1.9	0.6	-2.0	-1.7
Osteoporosis (self-reported)	0.3	0.3	1.4	-0.5	-1.2	-0.5	-0.5	-0.1	-0.1	0.7	-0.2	0.4	0.3	-0.6
Osteoarthritis (self-reported)	0.4	0.5	1.7	0.6	-0.5	0.4	0.6	-0.1	-0.5	1.1	0.9	-0.6	1.3	0.5
Medication: Aspirin	0.3	0.4	0.9	0.7	0.9	0.9	0.7	-0.4	-0.3	-0.5	-0.7	-0.7	-0.1	0.7
Medication: Gliclazide	0.4	0.4	1.3	-0.5	-0.5	-0.6	0.1	1.1	0.9	0.7	-0.4	0.4	-0.7	-0.5
Illnesses of father: None of the above (group 1)	0.1	0.1	0.6	0.0	-0.4	-0.1	-0.3	0.5	0.2	0.4	0.3	-0.0	0.2	-0.8
Smoking status: Current	0.3	0.4	1.6	-0.6	-0.5	-0.6	-0.1	-0.7	-0.4	-0.3	-1.0	0.4	0.4	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	4.6	0.4	0.8	0.2	0.2	0.5	-0.5	1.7	2.0	-0.3	0.5	2.1
Whole body water mass	0.6	3.3	15.5	-0.4	-2.1	-0.6	-0.1	1.4	0.2	3.9	2.5	0.1	2.2	1.4
Leg predicted mass (right)	0.3	1.7	8.6	-0.5	-1.4	-0.7	-0.3	1.2	0.4	2.9	1.5	0.3	1.6	0.6
Arm fat mass (left)	0.4	1.7	2.8	-1.4	-0.3	-1.6	-1.3	1.7	1.7	0.9	-1.2	1.2	-1.0	-1.2
Number of self-reported non-cancer illnesses	0.3	0.6	1.4	-0.7	1.2	-0.7	-0.7	0.1	0.4	-0.5	-1.0	0.7	-0.8	-0.8
Average weekly champagne plus white wine intake	0.0	0.0	0.2	0.2	-0.2	0.2	0.2	0.4	-0.0	0.2	-0.1	-0.3	-0.1	0.1
Miserableness	1.6	2.8	5.4	-2.1	-0.2	-1.9	-2.1	2.2	2.3	1.0	-0.7	2.1	-1.4	-0.3
Guilty feelings	1.0	1.5	4.8	-0.2	2.0	0.1	-0.5	-1.2	-0.4	-2.2	-1.1	0.3	-0.4	-2.0
Wears glasses or contact lenses	0.2	0.2	0.5	0.4	-0.7	0.4	0.4	-0.4	-0.6	0.5	-0.1	-0.5	0.0	0.5
Ever taken oral contraceptive pill	0.8	0.9	1.9	-1.3	0.2	-1.3	-1.1	0.9	1.2	-0.1	-0.5	1.4	-1.0	0.5
Hearing aid user	1.1	1.3	3.1	-1.1	-0.5	-1.1	-1.2	0.8	1.2	-0.4	-1.8	1.1	-1.4	-1.2
Mother’s age at death	0.4	0.6	2.6	-0.5	-0.4	-0.5	-0.4	-0.0	0.4	-0.8	-0.9	0.6	-0.8	-1.6
Financial situation satisfaction	0.3	0.4	1.2	-0.8	-0.8	-0.9	-0.2	0.2	0.0	1.1	0.7	0.7	-0.2	-0.5
Tinnitus: Yes, now most or all of the time	2.2	2.6	11.9	-1.3	-0.5	-1.5	-1.2	-0.4	0.7	-1.5	-2.4	1.2	-1.0	-3.4
Commuting to job workplace: Public transport	2.1	2.5	8.3	1.8	2.9	1.8	1.5	-1.2	-1.3	-1.5	-0.3	-1.8	0.2	-1.2
Eye problems/disorders: Glaucoma	1.2	1.4	3.1	1.5	1.8	1.4	1.3	-0.7	-1.3	0.1	1.2	-1.4	0.9	0.6
Medication: Blood pressure	0.4	0.7	1.8	0.7	0.1	0.7	1.0	-1.3	-1.3	-0.2	-0.6	-0.9	0.9	0.0
Pain type(s) experienced in last month: Hip pain	1.0	1.2	3.2	1.0	0.8	0.7	1.3	-0.7	-1.4	0.7	1.2	-1.1	1.8	0.9
Supplements: Fish oil (including cod liver oil)	1.4	1.8	4.2	-1.5	-2.0	-1.4	-1.6	1.2	1.1	1.6	0.7	1.5	-1.0	0.4
High cholesterol (Self-reported)	0.6	1.1	3.3	-0.6	0.7	-0.4	-0.6	-0.1	0.7	-1.8	-1.6	0.7	-1.4	-1.3
Medication: Bendroflumethiazide	0.5	0.8	2.8	0.7	1.7	0.7	0.6	-1.0	-0.9	-0.6	-0.7	-0.9	1.2	0.0
Medication: Paracetamol	0.3	0.5	2.6	-0.6	-1.6	-0.6	-0.4	-0.2	-0.0	0.8	-0.2	0.4	0.8	-0.3
Medication: Lisinopril	0.1	0.1	0.8	0.1	-0.4	0.0	-0.0	-0.6	-0.3	-0.3	-0.4	-0.1	-0.1	0.9
Medication: Atorvastatin	2.3	2.8	5.7	-2.4	-0.6	-2.2	-2.3	0.8	1.3	0.1	-1.9	2.2	-1.9	-0.6
Illnesses of father: High blood pressure	1.1	1.3	2.4	1.3	-0.6	1.4	1.5	-1.5	-1.4	-0.5	0.4	-1.4	1.2	0.4
Alcohol drinker status: Never	1.7	2.0	3.7	1.9	1.7	1.8	1.7	-1.4	-1.7	-0.8	0.2	-1.8	0.7	0.4
Ever smoked	0.5	0.8	3.2	-0.2	-1.5	-0.5	0.2	-1.5	-1.1	-0.0	-0.1	-0.0	1.8	-0.6
Basal metabolic rate	0.5	2.6	12.7	-0.7	-2.0	-0.9	-0.4	1.5	0.5	3.6	1.9	0.4	1.8	0.8
Leg fat percentage (left)	0.1	0.4	0.7	-0.4	-0.5	-0.6	-0.4	0.7	0.6	0.8	-0.8	0.3	-0.6	-0.7
Arm fat-free mass (left)	0.6	3.2	14.9	-0.9	-2.3	-1.1	-0.5	1.6	0.5	3.9	2.3	0.6	1.8	1.0
Number of operations (self-reported)	1.1	1.6	5.6	1.1	-0.3	1.0	1.4	-1.7	-1.6	0.3	0.4	-1.2	2.4	0.5
Average weekly beer plus cider intake	0.1	0.2	1.0	-0.3	0.1	-0.1	-0.2	0.1	0.6	-0.3	-1.0	0.3	-0.2	0.3
Irritability	0.6	1.1	2.1	-1.0	-0.4	-0.9	-1.4	-0.8	0.2	-1.4	-1.4	1.0	-0.6	-1.4
Risk taking	0.9	1.3	4.7	0.8	-2.2	0.8	0.7	-1.0	-1.0	0.3	0.2	-0.8	1.8	0.9
Ever had prostate specific antigen (PSA) test	0.8	1.0	3.4	-0.2	1.2	-0.2	-0.3	-0.9	-0.1	-1.9	-1.0	0.4	-0.8	-1.7
Fractured/broken bones in last 5 years	0.2	0.3	1.2	-0.4	1.1	-0.2	-0.5	-0.1	0.4	-0.7	0.5	0.6	-0.2	-0.7
Age started oral contraceptive pill	0.2	0.2	1.1	-0.0	-0.6	-0.1	0.2	0.1	-0.1	0.9	0.3	-0.0	0.1	1.0
Diastolic blood pressure, automated reading	0.1	0.2	1.2	0.1	0.9	0.4	0.1	-0.1	-0.1	0.1	0.5	-0.0	0.0	1.1
Ever depressed for a whole week	0.9	1.1	3.6	-0.9	-0.5	-0.9	-1.0	-0.2	0.8	-1.4	-1.4	1.0	-0.5	-1.9
Unable to work because of sickness or disability	0.1	0.2	1.8	0.1	1.3	0.0	0.2	-0.1	-0.1	-0.1	0.3	-0.1	-0.0	0.2
Commuting to job workplace: Cycle	0.2	0.3	1.1	0.6	0.7	0.7	0.1	-0.4	-0.4	-0.4	1.1	-0.4	0.4	0.3
Myopia	1.5	2.1	3.9	2.0	1.3	1.9	1.8	-1.3	-1.6	-0.5	-0.1	-2.0	1.6	0.3
Vascular/heart problems diagnosed by doctor	0.2	0.5	2.0	-0.4	-1.0	-0.5	-0.7	0.1	0.6	-0.7	-0.3	0.6	-0.8	-1.4
Cholesterol lowering medication	0.3	0.4	1.9	0.2	0.5	0.2	0.2	-0.7	-0.3	-1.0	-1.4	-0.3	-0.3	-0.9
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.9	-0.7	-0.7	-1.0	-0.6	-0.2	0.0	0.1	-1.1	0.5	-0.3	-1.7
Pain experienced in last month	0.6	0.9	3.5	0.9	1.9	1.2	0.7	-0.9	-1.0	-0.8	0.3	-0.8	-0.4	0.9
Supplements: Calcium	0.1	0.1	0.3	-0.1	0.4	-0.1	0.2	-0.2	-0.1	0.4	0.2	0.1	0.3	-0.6
Basal cell carcinoma (self-reported)	0.5	0.5	1.7	0.7	1.3	0.7	0.9	0.2	-0.2	0.6	0.9	-0.8	0.5	0.5
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.0	0.6	-0.6	0.5	0.6	-0.4	-0.5	0.6	-0.3	-0.7	0.7	1.4
Deep venous thrombosis (DVT) (self-reported)	0.0	0.0	0.1	-0.2	0.1	-0.1	-0.3	-0.1	0.1	-0.3	-0.2	0.2	-0.2	0.1
Heart disease (siblings)	0.2	0.2	0.5	0.6	-0.1	0.5	0.5	-0.7	-0.7	-0.3	0.2	-0.6	0.6	0.2
Alcohol drinker status: Previous	0.5	0.5	2.9	-0.1	0.8	-0.2	-0.2	-0.0	0.4	-1.0	-0.6	0.1	-0.7	-1.7
Pack years of smoking	0.7	1.0	2.2	-1.2	-1.5	-1.1	-1.0	1.0	1.1	0.9	0.1	1.1	0.3	-0.8
Impedance of whole body	0.1	0.4	1.9	0.3	1.4	0.4	0.0	-0.2	0.1	-1.2	-0.8	-0.2	-0.5	-0.3
Leg fat mass (left)	0.3	1.0	3.6	-0.9	-1.0	-1.1	-0.7	1.4	0.9	1.9	-0.2	0.6	-0.1	-0.6
Arm predicted mass (left)	0.7	3.4	15.8	-0.7	-2.4	-1.0	-0.4	1.7	0.5	4.0	2.4	0.4	1.9	1.2