Best TWAS P=5.22e-08 · Best GWAS P=4.81e-14 conditioned to 3.11e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Ovary | KREMEN1 | 0.28 | 0.18 | enet | 5 | 0.19 | 1.7e-05 | 4.6 | 5.4 | 8.1e-08 | -0.16 | 0.15 | 0.28 | TRUE |
| 2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | KREMEN1 | 0.13 | 0.10 | lasso | 5 | 0.11 | 3.3e-12 | 4.6 | 5.2 | 2.1e-07 | -0.04 | 0.01 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | HORMAD2 | 0.06 | 0.04 | enet | 10 | 0.07 | 5.7e-07 | 5.7 | -5.4 | 5.4e-08 | -0.05 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | MTMR3 | 0.21 | 0.08 | blup | 72 | 0.16 | 2.5e-15 | 5.4 | -5.4 | 5.2e-08 | 0.03 | 0.01 | 0.99 | TRUE |