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chr22:37,337,772-39,300,936

Best TWAS P=9.47e-12 · Best GWAS P=5.53e-11 conditioned to 0.000957

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	TRIOBP	0.13	0.14	lasso	7	0.14	3.9e-11	-4.91	5.5	3.5e-08	-0.86	0.77	0.23	FALSE
2	GTEx	Adipose Visceral Omentum	TRIOBP	0.16	0.14	enet	28	0.12	5.6e-07	-5.11	5.5	4.5e-08	-0.66	0.88	0.10	FALSE
3	GTEx	Adipose Visceral Omentum	GCAT	0.14	0.02	lasso	6	0.03	7.2e-03	2.85	-5.4	8.8e-08	0.55	0.09	0.21	FALSE
4	GTEx	Artery Aorta	TRIOBP	0.13	0.10	lasso	8	0.11	1.1e-06	-5.11	5.8	7.8e-09	-0.89	0.10	0.90	FALSE
5	GTEx	Artery Aorta	MICALL1	0.11	0.06	lasso	2	0.02	1.5e-02	-5.00	-5.1	2.7e-07	0.69	0.15	0.78	FALSE
6	GTEx	Artery Coronary	TRIOBP	0.27	0.14	lasso	4	0.14	2.2e-05	-6.24	6.3	3.5e-10	-0.92	0.03	0.92	FALSE
7	GTEx	Artery Tibial	GCAT	0.09	0.09	lasso	2	0.08	3.5e-07	-5.83	-6.1	1.1e-09	0.88	0.04	0.96	FALSE
8	GTEx	Artery Tibial	MICALL1	0.11	0.04	lasso	4	0.05	8.4e-05	-5.03	-5.5	3.1e-08	0.66	0.24	0.63	FALSE
9	GTEx	Artery Tibial	C22orf23	0.08	0.05	lasso	2	0.05	4.2e-05	-4.99	-5.2	2.1e-07	0.70	0.28	0.71	FALSE
10	GTEx	Breast Mammary Tissue	TRIOBP	0.11	0.10	enet	13	0.09	3.3e-05	-4.90	5.4	8.0e-08	-0.83	0.30	0.65	FALSE
11	GTEx	Breast Mammary Tissue (Male)	TRIOBP	0.16	0.06	lasso	6	0.06	1.8e-02	-5.11	5.7	1.3e-08	-0.78	0.04	0.36	FALSE
12	GTEx	Cells Transformed fibroblasts	TRIOBP	0.08	0.03	enet	11	0.09	3.0e-07	-4.98	6.0	1.8e-09	-0.89	0.13	0.86	FALSE
13	GTEx	Esophagus Mucosa	PLA2G6	0.22	0.02	lasso	6	0.04	1.9e-03	5.38	5.2	1.5e-07	0.05	0.62	0.24	FALSE
14	GTEx	Esophagus Muscularis	TRIOBP	0.07	0.06	lasso	3	0.06	1.7e-04	-5.01	5.4	7.5e-08	-0.73	0.55	0.23	FALSE
15	GTEx	Esophagus Muscularis	GCAT	0.11	0.12	lasso	3	0.12	1.1e-07	-4.91	-5.1	2.6e-07	0.80	0.75	0.24	FALSE
16	GTEx	Heart Atrial Appendage	TRIOBP	0.15	0.13	lasso	6	0.11	1.3e-05	-5.00	5.5	4.5e-08	-0.84	0.23	0.74	FALSE
17	GTEx	Nerve Tibial	TRIOBP	0.20	0.18	lasso	7	0.22	9.1e-16	-5.11	5.5	4.4e-08	-0.82	0.80	0.20	FALSE
18	GTEx	Pancreas	PLA2G6	0.28	0.00	lasso	6	0.01	1.4e-01	-3.30	6.8	9.5e-12	-0.56	0.03	0.72	TRUE
19	GTEx	Skin Not Sun Exposed Suprapubic	TRIOBP	0.12	0.04	lasso	3	0.05	7.0e-04	-6.24	6.2	5.4e-10	-0.90	0.03	0.95	FALSE
20	GTEx	Skin Sun Exposed Lower leg	TRIOBP	0.06	0.06	lasso	4	0.06	1.7e-05	-6.24	6.2	6.7e-10	-0.93	0.02	0.97	FALSE
21	GTEx	Stomach	TRIOBP	0.10	0.03	lasso	5	0.03	1.9e-02	-5.11	5.4	5.3e-08	-0.77	0.18	0.18	FALSE
22	GTEx	Whole Blood	H1F0	0.10	0.04	enet	17	0.08	1.1e-07	-5.83	-6.4	2.0e-10	0.78	0.04	0.96	FALSE
23	NTR	Blood	SH3BP1	0.02	0.00	blup	497	0.01	5.0e-03	-0.68	-5.7	1.6e-08	0.65	0.03	0.68	FALSE
24	YFS	Blood	H1F0	0.42	0.34	lasso	7	0.42	6.3e-150	-5.83	-5.4	5.1e-08	0.76	0.16	0.84	FALSE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIOBP	0.04	0.05	enet	16	0.06	3.0e-13	-5.12	6.2	6.1e-10	-0.90	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Glioblastoma Multiforme	GALR3	0.09	0.04	blup	27	0.06	8.8e-03	-5.83	-5.9	3.6e-09	0.87	0.02	0.63	FALSE
27	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	TRIOBP	0.12	0.14	enet	8	0.12	3.1e-07	-6.50	5.3	1.1e-07	-0.91	0.00	1.00	FALSE
28	The Cancer Genome Atlas	Brain Lower Grade Glioma	GALR3	0.04	0.04	lasso	2	0.05	3.4e-06	-5.01	-5.5	3.0e-08	0.71	0.04	0.95	FALSE
29	The Cancer Genome Atlas	Brain Lower Grade Glioma	GCAT	0.07	0.06	lasso	4	0.06	2.0e-07	-5.31	5.6	2.0e-08	-0.76	0.51	0.49	FALSE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRIOBP	0.08	0.07	enet	11	0.08	6.1e-09	-6.56	5.7	9.8e-09	-0.94	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Prostate Adenocarcinoma	GALR3	0.11	0.16	lasso	4	0.15	4.9e-15	-5.49	-5.5	3.6e-08	0.73	0.56	0.44	FALSE
32	The Cancer Genome Atlas	Prostate Adenocarcinoma	TRIOBP	0.07	0.04	blup	67	0.03	2.1e-04	-6.14	5.8	5.6e-09	-0.87	0.03	0.96	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	GCAT	0.02	0.03	blup	29	0.03	1.4e-03	-4.91	-5.7	1.3e-08	0.86	0.02	0.77	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	TRIOBP	0.22	0.25	enet	37	0.27	6.9e-26	-5.11	6.2	6.6e-10	-0.85	0.16	0.84	FALSE
35	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	GCAT	0.17	0.05	blup	29	0.07	4.8e-03	-5.83	6.4	2.1e-10	-0.87	0.01	0.78	FALSE