Best TWAS P=1.71e-08 · Best GWAS P=4.31e-09 conditioned to 5.67e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | HMGB1P31 | 0.31 | 0.23 | lasso | 5 | 0.19 | 3.8e-06 | -5.4 | -5.6 | 1.7e-08 | 0.08 | 0.00 | 0.98 | TRUE |
| 2 | GTEx | Colon Transverse | RP11-477N3.1 | 0.20 | 0.03 | lasso | 7 | 0.08 | 1.8e-04 | -3.4 | 5.2 | 1.5e-07 | -0.11 | 0.03 | 0.91 | FALSE |
| 3 | GTEx | Esophagus Muscularis | RP11-477N3.1 | 0.21 | 0.10 | lasso | 5 | 0.15 | 1.5e-09 | -5.4 | 5.2 | 1.7e-07 | -0.08 | 0.00 | 0.99 | FALSE |