[Hub]/) : Traits : Sitting height :

chr2:69,829,251-72,356,449

Best TWAS P=1.21e-28 · Best GWAS P=1.55e-30 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ZNF638 0.06 0.01 bslmm 559 0.02 1.8e-03 11.4 6.4 1.9e-10 0.69 0.01 0.96 FALSE
2 GTEx Adipose Subcutaneous PAIP2B 0.14 0.06 enet 23 0.05 8.7e-05 4.8 5.6 2.6e-08 0.37 0.94 0.01 FALSE
3 GTEx Artery Aorta ZNF638 0.25 0.07 enet 20 0.10 5.2e-06 11.4 11.1 1.2e-28 0.98 0.01 0.99 TRUE
4 GTEx Artery Aorta PAIP2B 0.09 0.02 lasso 3 0.02 3.0e-02 5.4 5.5 3.9e-08 0.59 0.28 0.04 FALSE
5 GTEx Artery Tibial ZNF638 0.10 0.06 enet 13 0.07 2.4e-06 11.3 9.6 1.3e-21 0.88 0.01 0.98 FALSE
6 GTEx Cells EBV-transformed lymphocytes FAM136A 0.31 0.12 lasso 7 0.16 5.6e-06 4.5 5.5 4.0e-08 0.02 0.04 0.92 TRUE
7 GTEx Skin Sun Exposed Lower leg PAIP2B 0.14 0.07 enet 39 0.07 3.0e-06 8.5 7.3 3.4e-13 0.66 0.33 0.63 FALSE
8 GTEx Thyroid ZNF638 0.11 0.04 enet 13 0.06 1.3e-05 4.1 5.8 6.4e-09 0.66 0.07 0.91 FALSE
9 METSIM Adipose PAIP2B 0.05 0.03 lasso 9 0.03 5.0e-05 8.5 7.6 2.3e-14 0.75 0.60 0.33 FALSE
10 NTR Blood PAIP2B 0.03 0.02 lasso 5 0.01 1.2e-04 -3.4 -5.2 2.0e-07 -0.38 0.89 0.02 FALSE
11 The Cancer Genome Atlas Esophageal Carcinoma ZNF638 0.12 0.08 lasso 1 0.07 2.2e-03 7.8 7.8 6.3e-15 0.76 0.05 0.66 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma ZNF638 0.08 0.05 enet 10 0.05 5.6e-06 11.4 9.2 5.4e-20 0.88 0.01 0.99 FALSE