[Hub]/) : Traits : Sitting height :

chr2:84,884,961-86,513,102

Best TWAS P=1.92e-11 · Best GWAS P=1.68e-10 conditioned to 0.236

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta GGCX 0.23 0.22 lasso 6 0.23 5.5e-13 4.5 5.4 5.8e-08 0.61 0.86 0.14 FALSE
2 GTEx Artery Tibial GGCX 0.29 0.22 enet 14 0.24 6.3e-19 4.5 5.7 1.2e-08 0.62 0.98 0.02 FALSE
3 GTEx Colon Transverse GGCX 0.26 0.28 lasso 3 0.28 1.4e-13 4.5 5.1 2.8e-07 0.52 0.96 0.04 FALSE
4 GTEx Esophagus Gastroesophageal Junction GGCX 0.24 0.16 lasso 6 0.12 4.3e-05 4.6 5.2 1.5e-07 0.52 0.15 0.75 FALSE
5 GTEx Nerve Tibial GGCX 0.38 0.30 lasso 7 0.33 6.5e-24 4.5 5.5 3.4e-08 0.68 0.98 0.02 FALSE
6 GTEx Pancreas VAMP5 0.29 0.09 enet 4 0.05 3.2e-03 6.4 -6.3 3.9e-10 -0.92 0.01 0.89 FALSE
7 GTEx Skin Sun Exposed Lower leg GGCX 0.15 0.11 lasso 3 0.18 7.9e-15 4.5 6.2 6.0e-10 0.78 0.05 0.95 FALSE
8 GTEx Testis GGCX 0.38 0.36 enet 25 0.40 8.6e-19 4.6 5.2 2.6e-07 0.65 0.86 0.14 FALSE
9 GTEx Thyroid ELMOD3 0.10 0.01 enet 10 0.02 7.7e-03 -2.9 5.1 3.1e-07 0.37 0.15 0.54 FALSE
10 GTEx Thyroid GGCX 0.30 0.17 enet 10 0.23 1.4e-17 4.5 5.7 9.3e-09 0.67 0.91 0.09 FALSE
11 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma VAMP8 0.06 0.01 enet 15 0.02 2.1e-02 6.1 6.4 1.5e-10 0.87 0.00 0.88 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma GGCX 0.04 0.02 blup 44 0.02 2.7e-03 6.0 6.7 1.9e-11 0.86 0.01 0.97 TRUE