TWAS hub - FAM136A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.1610	0.0760	9.0e-03	0.005	NA	0.025	NA	0.005	1.1e-01	NA	3.6e-03	NA	1.1e-01
2	GTEx	Artery Tibial	0.1061	0.0381	5.1e-04	0.019	NA	0.050	NA	0.033	1.1e-02	NA	8.2e-05	NA	1.3e-03
3	GTEx	Cells EBV-transformed lymphocytes	0.3060	0.0740	2.3e-06	0.121	NA	0.162	NA	0.163	9.3e-05	NA	5.7e-06	NA	5.6e-06
4	GTEx	Cells Transformed fibroblasts	0.2180	0.0530	1.2e-09	0.167	NA	0.110	NA	0.144	1.5e-12	NA	1.4e-08	NA	6.2e-11
5	GTEx	Heart Left Ventricle	0.1666	0.0593	1.7e-04	0.092	NA	0.088	NA	0.082	1.3e-05	NA	2.0e-05	NA	4.0e-05
6	GTEx	Lung	0.1026	0.0420	6.0e-03	-0.003	NA	-0.004	NA	-0.001	8.3e-01	NA	9.4e-01	NA	4.3e-01
7	GTEx	Skin Sun Exposed Lower leg	0.1060	0.0410	2.3e-04	0.053	NA	0.064	NA	0.045	3.1e-05	NA	5.1e-06	NA	1.2e-04
8	GTEx	Thyroid	0.1290	0.0410	5.5e-05	0.061	NA	0.062	NA	0.053	1.9e-05	NA	1.7e-05	NA	6.8e-05
9	METSIM	Adipose	0.0486	0.0174	2.2e-05	0.013	0.028	0.025	0.029	0.022	3.9e-03	3.7e-05	1.0e-04	2.8e-05	2.4e-04
10	ROSMAP	Brain Pre-frontal Cortex	0.0880	0.0406	9.4e-06	0.079	0.047	0.056	0.058	0.065	2.6e-10	1.1e-06	1.1e-07	5.0e-08	9.8e-09
11	YFS	Blood	0.0297	0.0095	7.7e-07	0.024	0.024	0.024	0.027	0.026	1.7e-08	1.7e-08	1.5e-08	2.2e-09	4.7e-09
12	TCGA	Bladder Urothelial Carcinoma	0.0510	0.0300	4.4e-04	0.047	0.044	0.036	NA	0.035	7.4e-05	1.3e-04	4.5e-04	NA	5.7e-04
13	TCGA	Breast Invasive Carcinoma	0.0262	0.0133	3.9e-06	0.036	0.025	0.033	NA	0.034	4.6e-08	5.2e-06	1.7e-07	NA	1.3e-07
14	TCGA	Colon Adenocarcinoma	0.0970	0.0450	1.4e-05	0.122	0.088	0.083	NA	0.117	1.6e-07	8.7e-06	1.5e-05	NA	3.0e-07
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0430	0.0252	4.6e-04	0.031	0.036	0.029	NA	0.031	1.7e-04	6.0e-05	3.2e-04	NA	1.8e-04
16	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0720	0.0470	5.2e-03	0.032	0.034	0.017	NA	0.043	6.0e-03	4.6e-03	3.5e-02	NA	1.6e-03
17	TCGA	Brain Lower Grade Glioma	0.0200	0.0132	8.7e-03	0.005	0.010	-0.001	NA	0.002	7.7e-02	2.2e-02	5.4e-01	NA	2.0e-01
18	TCGA	Lung Adenocarcinoma	0.0416	0.0206	8.6e-05	0.032	0.032	0.016	NA	0.030	1.2e-04	1.2e-04	4.9e-03	NA	1.8e-04
19	TCGA	Lung Squamous Cell Carcinoma	0.0844	0.0494	7.2e-05	0.038	0.041	0.036	NA	0.037	3.2e-05	1.6e-05	5.1e-05	NA	4.1e-05
20	TCGA	Ovarian Serous Cystadenocarcinoma	0.0570	0.0440	7.9e-03	0.006	0.003	0.004	NA	0.002	1.2e-01	1.9e-01	1.7e-01	NA	2.4e-01
21	TCGA	Pancreatic Adenocarcinoma	0.1950	0.0810	7.8e-05	0.025	0.069	0.050	NA	0.057	3.1e-02	7.5e-04	3.8e-03	NA	2.1e-03
22	TCGA	Soft Tissue Sarcoma	0.0760	0.0480	4.2e-03	0.019	0.027	0.028	NA	0.024	2.4e-02	9.1e-03	8.7e-03	NA	1.4e-02
23	TCGA	Stomach Adenocarcinoma	0.0390	0.0230	8.4e-03	0.039	0.026	0.037	NA	0.038	8.0e-04	5.1e-03	1.1e-03	NA	8.5e-04
24	TCGA	Thyroid Carcinoma	0.0530	0.0290	2.0e-04	0.041	0.042	0.038	NA	0.043	6.6e-05	5.7e-05	1.2e-04	NA	4.5e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24
Forced vital capacity (FVC)	5.0	19.3	47.2	-0.6	6.9	5.4	5.2	3.2	1.4	-3.5	-1.8	5.2	-3.1	4.8	5.4	5.4	4.1	3.9	5.2	4.4	4.8	5.4	3.7	5.2	4.3	4.9
High cholesterol (Self-reported)	4.9	8.8	23.2	0.4	-4.8	-3.7	-3.4	-3.4	-2.3	0.6	0.8	-3.2	-0.3	-3.1	-3.6	-3.6	-3.3	-3.0	-3.1	-3.2	-2.1	-3.3	-2.7	-3.4	-3.4	-3.5
Hair/balding pattern: Pattern 4	4.7	11.5	28.9	-2.3	-5.4	-4.2	-3.7	-3.7	-1.4	1.4	1.1	-3.9	0.3	-4.0	-4.2	-4.1	-4.1	-3.6	-3.1	-3.3	-3.4	-3.7	-3.7	-2.8	-3.7	-4.0
Depression (self-reported)	4.4	5.3	11.2	1.5	-3.3	-2.8	-3.3	-2.0	-3.1	1.2	-0.2	-1.6	0.4	-2.6	-2.8	-2.8	-2.3	-1.3	-3.0	-2.9	-1.4	-3.2	-0.6	-2.3	-2.5	-2.6
Forced vital capacity (FVC), Best measure	4.4	16.1	43.7	-0.9	6.6	5.0	4.8	3.3	1.7	-2.8	-1.6	4.4	-2.3	4.4	5.0	5.0	4.0	3.4	4.6	4.1	4.0	5.0	3.3	4.5	4.1	4.6
Prostate Cancer	4.3	6.1	10.1	0.2	1.9	3.0	2.4	2.6	3.2	-1.5	1.2	2.3	0.1	3.0	3.1	3.0	3.2	3.0	2.5	2.8	2.0	2.7	2.4	2.6	2.7	2.9
Rheumatoid Arthritis	3.4	4.7	12.5	-1.1	-3.5	-2.2	-2.4	-3.0	-2.4	-0.5	-0.8	-2.7	-1.0	-2.9	-2.1	-2.3	-2.3	-2.3	-2.0	-3.2	0.5	-1.8	0.2	-2.0	-2.6	-2.6
Lung FVC	3.2	16.2	31.5	-0.4	5.6	4.8	4.8	3.1	2.1	-3.7	-2.9	4.6	-3.7	4.3	5.0	5.0	3.6	2.5	5.2	4.0	4.8	5.2	2.7	4.3	3.7	4.4
Forced expiratory volume in 1-second (FEV1)	3.1	10.3	26.9	0.1	5.2	3.9	3.7	2.5	0.6	-2.5	-2.2	4.0	-2.3	3.6	3.9	3.9	2.9	2.6	3.9	3.1	3.5	4.1	2.4	3.6	3.0	3.5
Commuting to job workplace: Cycle	3.0	3.6	9.3	-0.2	2.6	2.3	2.2	1.4	1.2	-0.9	0.5	1.8	-0.3	2.0	2.2	2.4	1.9	2.6	1.9	2.2	1.2	1.7	1.7	3.0	2.2	2.4
Hair/balding pattern: Pattern 2	2.9	3.7	8.4	-0.8	2.4	2.2	2.0	2.9	1.3	1.1	1.2	0.7	2.0	1.9	2.2	2.1	2.6	2.6	0.9	2.4	0.0	1.7	2.3	2.0	2.5	2.3
Forced expiratory volume in 1-second (FEV1), Best measure	2.9	9.4	27.4	-0.3	5.2	3.8	3.6	2.6	1.4	-2.1	-1.7	3.4	-1.8	3.6	3.8	3.8	3.1	2.3	3.7	3.2	2.9	4.0	2.0	3.2	3.1	3.5
Hair/balding pattern: Pattern 3	2.8	4.1	7.7	0.8	-2.6	-2.2	-2.7	-2.7	-2.4	-1.2	-1.9	-0.2	-2.5	-1.6	-2.1	-2.0	-2.4	-2.3	-0.6	-2.7	1.0	-1.6	-1.8	-2.2	-2.8	-2.4
Mouth/teeth dental problems: Bleeding gums	2.8	3.6	7.3	0.1	-2.7	-2.3	-2.6	-1.9	-0.6	0.2	-1.2	-0.7	-0.0	-2.2	-2.3	-2.3	-2.7	-2.6	-1.7	-2.4	-1.0	-1.6	-2.0	-2.3	-2.4	-2.4
Medication: Allopurinol	2.8	3.7	11.2	0.2	3.4	2.4	1.7	2.0	1.7	0.3	1.6	1.7	0.9	2.2	2.3	2.3	2.3	2.7	0.8	2.3	0.2	1.7	2.1	1.9	2.6	2.5
Lupus	2.7	4.1	8.5	0.6	-2.9	-2.6	-2.2	-1.6	-1.4	1.6	0.3	-2.6	0.7	-1.9	-2.5	-2.7	-2.0	-1.9	-1.9	-2.0	-1.7	-2.4	-2.2	-2.4	-2.5	-2.5
Had menopause	2.7	3.4	11.2	-1.0	-3.4	-2.3	-1.9	-1.9	-0.0	1.2	-0.0	-2.2	0.4	-2.4	-2.3	-2.3	-2.3	-1.7	-1.7	-1.9	-1.6	-2.1	-1.6	-0.9	-2.1	-2.3
Breastfed as a baby	2.7	3.3	9.1	-1.1	2.6	2.1	2.3	1.5	2.1	-0.3	0.3	-0.1	-0.2	2.0	2.1	2.1	1.6	2.2	1.8	2.5	0.5	2.3	0.9	3.0	2.1	2.2
Illnesses of mother	2.6	3.3	9.8	-1.4	3.1	2.0	2.1	1.0	-0.6	-1.8	-0.8	0.9	-1.8	2.2	2.1	2.0	1.9	1.9	2.2	1.3	2.5	2.1	1.9	1.8	1.3	1.7
Age started oral contraceptive pill	2.6	3.2	11.4	-0.9	1.9	1.8	2.0	1.4	3.4	1.0	2.7	0.6	1.3	1.5	1.7	1.7	1.6	2.2	0.9	2.6	-0.9	1.3	0.7	2.7	2.4	2.0
Alcohol usually taken with meals	2.3	3.6	10.4	-0.8	2.9	2.0	2.2	1.8	3.2	1.4	1.5	0.5	1.4	2.3	2.0	2.1	2.3	1.7	1.4	2.7	-0.5	1.8	0.3	1.5	2.6	2.4
LDL Cholesterol	2.2	3.4	5.3	-0.6	-2.1	-2.2	-1.9	-2.2	-2.3	0.8	-0.4	-2.3	0.2	-2.2	-2.3	-2.2	-2.0	-2.2	-2.1	-2.2	-1.5	-1.7	-1.1	-2.1	-2.0	-2.2
Hearing difficulty/problems: Yes	2.2	3.3	7.5	1.9	-2.7	-2.3	-2.0	-1.4	-1.5	1.5	0.0	-0.8	0.4	-2.0	-2.4	-2.3	-2.0	-1.4	-1.9	-2.3	-1.3	-2.4	-1.2	-1.8	-2.1	-2.2
Standing height	2.2	22.2	54.3	-2.8	7.4	5.8	5.9	4.5	3.6	0.1	3.3	4.1	1.5	4.9	5.6	5.6	5.2	5.4	3.9	6.0	1.2	4.8	3.9	6.0	5.9	5.8
Neck or shoulder pain in last month	2.2	3.1	10.9	2.5	-1.4	-1.4	-1.7	0.9	-1.0	3.3	2.4	-0.3	3.2	-1.6	-1.6	-1.6	-0.4	-0.5	-2.5	-0.6	-2.9	-2.5	-0.6	-1.7	-0.4	-1.0
Qualifications: nursing, teaching	2.2	3.3	8.6	0.9	2.9	2.2	2.1	1.3	0.9	0.5	-0.0	2.3	0.4	2.1	2.1	2.1	2.0	2.4	1.7	2.5	1.0	1.8	1.6	2.5	2.1	2.2
Medication for cholesterol	2.2	3.3	8.5	-1.3	2.9	2.4	2.1	2.1	1.6	-0.9	0.7	0.5	0.3	2.0	2.3	2.3	1.9	1.6	1.6	2.2	0.8	2.3	1.4	1.8	2.3	2.3
Hearing aid user	2.2	2.5	11.4	-0.9	-1.4	-1.3	-0.9	0.2	0.7	3.4	2.1	-2.1	2.4	-1.6	-1.4	-1.4	-1.0	-1.1	-2.0	-0.4	-2.9	-1.7	-1.3	-1.0	-0.4	-0.9
Blood Platelet Count	2.1	23.9	52.1	6.0	6.7	5.0	5.0	7.2	5.4	1.5	4.9	5.6	3.1	4.6	4.8	5.0	6.4	6.1	1.4	5.6	-0.7	2.2	4.5	3.3	6.5	6.0
Medication: Lansoprazole	2.1	2.4	7.4	1.4	-2.0	-1.8	-1.7	-0.7	-0.7	1.0	-0.9	-1.4	0.8	-1.9	-1.8	-1.8	-1.2	-1.9	-2.2	-2.2	-0.4	-1.7	-0.1	-2.7	-1.7	-1.7
Ever highly irritable/argumentative for 2 days	2.1	2.6	11.6	0.4	-1.1	-1.3	-0.8	0.3	-1.3	3.4	1.2	-2.1	2.6	-0.9	-1.4	-1.4	-0.5	-0.8	-1.9	-0.5	-2.9	-1.9	-1.7	-2.4	-0.5	-1.0
Number of self-reported non-cancer illnesses	2.1	3.7	9.6	-0.0	-3.1	-2.2	-2.0	-1.2	-1.4	1.6	2.2	-2.5	1.6	-2.1	-2.2	-2.3	-1.7	-1.4	-2.2	-1.5	-2.6	-2.2	-1.7	-1.7	-1.5	-2.0
Cholesterol lowering medication	2.1	3.0	6.2	0.1	-2.5	-2.3	-1.8	-2.0	-1.6	0.9	-0.5	-1.1	-0.2	-1.8	-2.2	-2.2	-1.9	-1.9	-1.9	-1.9	-1.4	-1.8	-1.6	-2.2	-2.0	-2.1
Cardiovascular Disease	2.0	6.5	17.4	1.8	-4.2	-3.1	-3.1	-2.4	-2.9	1.8	0.5	-2.3	1.0	-2.9	-3.1	-3.1	-2.4	-1.0	-3.5	-3.1	-1.8	-3.4	-0.3	-2.3	-2.8	-3.0
Financial difficulties in last 2 years	2.0	2.7	5.9	0.2	-2.2	-1.9	-2.0	-1.0	-0.9	1.1	0.6	-1.8	1.1	-2.1	-2.0	-1.9	-1.5	-1.6	-2.4	-2.0	-1.3	-2.1	-0.7	-2.2	-1.6	-1.7
Comparative height size at age 10	2.0	11.0	29.7	-0.7	5.5	4.0	4.2	3.2	2.2	0.1	2.5	3.7	1.1	3.4	3.8	3.8	3.9	4.1	2.4	3.8	1.4	3.2	3.4	3.8	4.0	4.0
Handedness (chirality/laterality): Left-handed	2.0	2.4	8.1	-0.3	1.9	1.5	1.6	1.4	0.1	-1.8	-1.4	2.9	-1.4	1.8	1.5	1.6	1.0	1.2	2.2	1.4	1.5	2.2	0.3	2.0	1.1	1.3
Medication: Blood pressure	2.0	3.8	11.2	1.7	-3.3	-2.5	-2.5	-1.4	-1.3	2.1	0.9	-0.9	1.3	-2.1	-2.5	-2.5	-1.6	-0.6	-2.2	-1.9	-1.8	-3.3	-1.0	-1.3	-2.0	-2.3
Ever depressed for a whole week	2.0	2.4	5.0	-1.1	-2.2	-1.9	-1.5	-1.6	-0.8	0.0	-1.1	-1.5	-0.0	-1.9	-1.9	-1.8	-2.0	-2.2	-1.2	-1.7	-1.1	-1.5	-1.7	-1.5	-1.9	-1.9
Primary Biliary Cirrhosis	1.9	2.7	7.4	1.5	-2.7	-2.0	-2.4	-1.1	-1.6	1.5	-0.1	-1.2	0.9	-2.0	-2.0	-2.1	-1.7	-1.0	-2.0	-1.6	-1.3	-2.1	-0.6	-1.1	-1.7	-1.9
Gout (self-reported)	1.9	2.6	7.7	1.2	2.4	1.9	1.3	1.2	0.3	-0.2	0.4	2.2	0.3	1.8	1.9	1.8	1.7	2.8	0.9	1.6	0.9	1.2	2.1	2.2	1.8	1.8
Alcohol intake frequency.	1.9	4.4	11.6	-1.0	-2.5	-2.4	-2.0	-0.5	-0.9	1.7	0.9	-3.4	1.8	-2.1	-2.4	-2.4	-1.9	-2.4	-2.4	-2.0	-2.7	-2.0	-2.1	-2.9	-1.8	-2.2
Alzheimer’s Disease (in father)	1.8	1.9	5.2	0.4	-1.5	-1.4	-1.5	-0.4	1.0	1.4	1.9	-0.9	1.5	-1.4	-1.5	-1.5	-1.0	-1.7	-1.9	-0.8	-2.3	-1.3	-1.4	-2.0	-0.8	-1.1
Other serious medical condition/disability diagnosed by doctor	1.8	2.4	4.8	-0.9	1.9	1.9	2.2	0.8	0.7	-1.2	-0.7	1.3	-1.0	1.5	1.9	1.9	1.5	1.4	1.9	1.4	1.7	2.0	1.4	2.1	1.4	1.6
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.7	9.4	-1.9	3.1	2.4	2.4	2.1	1.3	-0.2	0.7	0.5	1.0	2.2	2.3	2.3	2.4	2.0	1.5	2.5	0.7	2.3	1.8	1.9	2.3	2.4
Loneliness, isolation	1.8	2.4	6.9	-1.2	-2.6	-1.8	-1.5	-0.9	-1.6	0.6	0.2	-1.4	1.0	-2.1	-1.8	-1.8	-1.9	-1.3	-2.4	-2.1	-1.1	-1.5	-0.1	-1.5	-1.7	-1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.8	2.1	7.2	0.2	2.3	1.7	2.1	2.2	0.7	0.4	1.3	0.2	1.2	0.7	1.7	1.6	2.0	1.2	-0.1	1.1	0.6	1.0	2.7	0.4	1.9	1.9
Medication: Bendroflumethiazide	1.8	2.8	8.1	-0.7	-2.8	-2.0	-1.8	-1.3	-1.5	1.3	0.6	-2.0	1.1	-2.1	-2.0	-2.1	-1.2	-1.1	-1.9	-1.9	-1.2	-2.3	-0.3	-1.5	-1.7	-1.9
Leg fat percentage (left)	1.8	6.5	15.5	0.1	-3.9	-3.2	-2.9	-2.6	-2.5	-0.3	-0.9	-2.9	-0.2	-2.5	-3.1	-3.2	-2.7	-2.8	-2.1	-3.1	-0.9	-2.6	-2.1	-3.3	-3.3	-3.3
Hypothyroidism (self reported)	1.7	3.9	12.2	0.3	-3.5	-2.2	-1.5	-2.3	-3.1	1.1	-1.2	-2.0	-0.3	-2.8	-2.2	-2.2	-2.3	-1.0	-2.5	-2.7	-0.4	-2.4	0.7	-0.8	-2.0	-2.2
Medication: Atenolol	1.7	2.1	4.9	-1.6	-2.2	-1.7	-1.4	-1.7	-1.1	0.0	-1.5	-1.4	-0.8	-1.5	-1.6	-1.7	-1.9	-1.8	-0.8	-1.6	-0.8	-0.9	-1.6	-1.1	-1.9	-1.9
Sitting height	1.7	11.9	30.1	0.1	5.5	4.2	4.3	3.5	3.2	-0.7	1.5	3.4	0.6	3.9	4.1	4.2	3.9	3.9	3.0	4.4	1.4	3.4	2.7	3.8	4.4	4.4
Qualifications: None of the above	1.7	3.6	9.2	0.0	-2.7	-2.3	-2.1	-2.0	-1.4	-1.0	-0.9	-1.3	-1.7	-1.9	-2.1	-2.1	-1.9	-2.5	-1.3	-3.0	0.3	-1.3	-1.2	-3.0	-2.6	-2.5
Alcohol intake versus 10 years previously	1.7	2.6	8.7	0.1	-1.6	-1.9	-1.3	-1.4	-0.5	0.1	-0.9	-1.4	-0.4	-1.7	-1.9	-1.9	-1.7	-3.0	-1.3	-2.2	-0.7	-0.8	-1.7	-2.9	-1.9	-2.1
Qualifications: A levels/AS levels or equivalent	1.7	3.8	12.2	-0.5	2.3	2.5	2.1	0.0	0.5	-0.9	-1.2	2.5	-1.4	1.8	2.4	2.4	1.4	2.1	2.2	2.3	1.8	2.2	1.6	3.5	1.9	2.3
Leg fat percentage (right)	1.7	6.0	13.4	0.0	-3.7	-3.0	-2.7	-2.3	-2.4	-0.1	-0.6	-2.9	0.1	-2.5	-3.0	-3.1	-2.5	-2.7	-2.3	-3.0	-1.1	-2.5	-1.8	-3.3	-3.1	-3.1
Hand grip strength (left)	1.6	4.3	12.6	-2.6	3.5	1.8	1.5	-0.1	-2.9	-1.9	-3.5	1.3	-3.1	2.2	1.9	1.9	1.0	0.5	2.7	0.5	3.3	2.9	1.0	0.8	0.6	1.2
Blood clot in the leg (DVT)	1.6	2.0	5.2	-0.1	2.3	1.6	1.4	2.0	2.3	0.6	0.4	1.1	0.9	1.8	1.6	1.4	1.7	1.5	1.4	2.0	-0.1	1.4	0.1	1.3	1.6	1.6
Age at First Birth	1.5	2.1	13.9	-0.4	-0.1	0.9	1.2	-0.6	-0.4	-3.7	-2.4	0.3	-3.0	0.5	1.0	0.9	0.1	0.4	1.7	-0.1	3.1	1.1	1.1	1.3	-0.2	0.3
High blood pressure (mother)	1.5	2.2	6.1	2.1	-2.5	-1.6	-1.9	-0.2	-0.2	0.9	0.5	-0.9	1.6	-1.8	-1.6	-1.7	-1.3	-1.3	-1.9	-1.2	-1.7	-1.9	-1.1	-1.6	-1.1	-1.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.5	1.8	7.0	2.0	1.3	0.8	0.7	1.9	2.6	0.9	1.6	0.3	2.2	1.2	0.7	0.9	1.5	1.1	0.4	1.9	-1.4	0.1	-0.6	0.4	1.6	1.4
Arm fat percentage (left)	1.5	5.9	15.9	-0.3	-4.0	-3.0	-2.8	-2.3	-2.6	-0.2	-1.3	-2.4	-0.2	-2.6	-3.0	-3.0	-2.8	-2.6	-2.0	-3.0	-0.9	-2.4	-1.8	-2.7	-3.1	-3.1
Ever had stillbirth, spontaneous miscarriage or termination	1.5	1.6	3.2	-0.3	-1.8	-1.6	-1.4	-1.1	0.1	1.3	0.2	-0.8	0.3	-1.6	-1.6	-1.6	-1.2	-1.8	-1.1	-1.5	-0.8	-1.4	-1.3	-1.7	-1.5	-1.6
Financial situation satisfaction	1.5	1.9	4.2	0.0	2.1	1.8	1.5	1.3	0.8	-0.0	-2.0	1.8	-0.6	1.4	1.7	1.8	1.2	0.5	1.3	1.0	1.7	2.0	1.1	0.8	1.3	1.5
Blood Red Count	1.4	13.4	34.0	5.5	5.8	3.8	3.1	4.1	4.1	1.3	3.7	4.6	2.1	3.6	3.7	3.7	4.8	4.3	1.4	3.7	0.5	2.3	3.5	2.2	4.4	4.3
Qualifications: CSEs or equivalent	1.4	1.8	3.9	-0.2	-1.7	-1.4	-0.8	-1.7	-1.4	-1.7	-1.4	-0.3	-1.7	-1.1	-1.3	-1.3	-2.0	-1.7	-0.4	-1.7	0.4	-0.8	-1.4	-1.2	-1.9	-1.7
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	7.2	-0.1	-2.6	-1.7	-1.5	-2.2	-2.7	0.5	-1.7	-1.5	-1.0	-2.1	-1.6	-1.6	-1.9	-1.1	-1.8	-2.4	0.3	-1.5	0.6	-0.9	-1.7	-1.8
Birth weight	1.4	3.0	8.3	0.6	2.5	2.0	1.5	1.6	0.7	-0.7	-1.0	2.2	-0.4	1.6	2.0	1.9	1.7	2.5	1.9	1.6	1.9	1.3	1.9	2.9	1.6	1.9
Body fat percentage	1.4	5.5	15.6	-0.6	-4.0	-2.9	-2.7	-2.4	-2.1	-0.2	-0.7	-2.6	0.0	-2.6	-2.9	-2.9	-2.7	-2.5	-2.0	-2.8	-1.0	-2.4	-1.7	-2.6	-3.0	-3.0
Worry too long after embarrassment	1.4	2.4	4.7	-1.9	-2.2	-1.7	-1.2	-1.3	-1.7	1.0	-0.3	-1.7	0.2	-1.9	-1.7	-1.8	-2.0	-1.9	-1.7	-1.6	-1.5	-0.9	-1.2	-1.4	-1.7	-1.8
Qualifications: College or University degree	1.4	4.3	14.4	-0.0	2.6	2.6	2.3	1.1	0.9	-0.3	0.7	2.6	-0.2	1.6	2.5	2.6	1.9	2.7	1.6	2.5	1.2	2.0	2.5	3.8	2.5	2.6
Average weekly champagne plus white wine intake	1.4	1.9	5.4	0.0	1.6	1.5	1.8	1.1	2.3	-0.0	-1.0	1.4	-0.3	1.6	1.5	1.5	1.1	1.3	1.7	1.8	0.7	1.6	0.3	2.1	1.4	1.5
Alzheimer’s Disease (in mother)	1.3	1.5	6.8	-0.6	1.0	-1.1	-1.2	-1.8	1.3	-0.8	-1.3	-0.5	-1.1	-0.5	-1.1	-1.0	-1.7	-2.2	0.2	-0.8	-0.1	0.0	-2.6	-1.4	-1.4	-1.3
Major Depression (MDD)	1.3	1.6	3.8	-0.6	-1.5	-1.4	-1.4	-1.7	-1.2	0.3	-0.7	-1.9	0.1	-1.3	-1.4	-1.7	-1.6	-0.6	-1.1	-1.5	-0.7	-1.4	-0.8	-0.7	-1.8	-1.8
Verbal and Numeric Reasoning (VNR)	1.3	3.0	9.5	-0.6	2.6	1.8	1.6	-0.2	1.2	-1.9	-0.5	2.9	-2.0	1.4	1.8	1.8	0.9	1.4	2.5	1.9	1.9	1.8	0.6	3.1	1.3	1.6
Height	1.3	24.6	57.6	-2.1	7.6	6.0	5.8	5.5	5.3	0.8	4.1	4.2	2.5	5.4	5.8	5.7	5.7	5.3	4.2	6.8	0.4	4.7	2.9	5.8	6.4	6.1
Ever had hysterectomy (womb removed)	1.3	1.4	5.0	1.5	1.0	1.1	0.9	2.2	0.4	1.3	0.3	1.8	1.7	0.6	1.0	1.0	1.3	1.6	0.1	1.0	0.1	0.2	1.7	1.2	1.5	1.3
Diabetes (mother)	1.3	1.7	6.6	-2.6	-1.3	-1.1	-0.8	-1.6	-1.3	-0.4	-2.5	-1.3	-1.2	-0.7	-0.9	-1.0	-1.1	-1.7	0.2	-1.5	0.6	-0.2	-1.0	-1.5	-1.6	-1.4
Fed-up feelings	1.3	2.3	6.2	-1.8	-2.4	-1.6	-1.5	-1.6	-2.5	-0.9	-0.9	-1.5	-0.2	-1.6	-1.6	-1.6	-1.7	-1.6	-1.4	-1.8	-0.5	-1.2	-0.8	-1.5	-1.8	-1.7
Ever unenthusiastic/disinterested for a whole week	1.3	1.6	5.2	-1.2	-0.9	-1.4	-1.5	-1.0	-1.4	0.7	-1.8	-0.5	0.5	-0.7	-1.4	-1.3	-1.5	-1.8	-0.5	-1.2	-1.0	-0.9	-2.3	-1.8	-1.4	-1.5
Arm fat percentage (right)	1.3	5.2	13.9	-0.3	-3.7	-2.8	-2.6	-2.2	-2.7	-0.2	-1.2	-2.2	-0.1	-2.5	-2.8	-2.8	-2.6	-2.3	-2.0	-2.9	-0.8	-2.2	-1.4	-2.5	-2.9	-2.9
Trunk fat-free mass	1.3	7.5	19.4	-0.5	4.4	3.2	3.2	3.4	0.1	0.3	2.2	2.0	1.8	3.2	3.0	3.0	3.5	3.9	1.9	3.5	0.3	2.4	2.6	3.0	3.5	3.4
Trunk predicted mass	1.3	7.6	19.6	-0.4	4.4	3.2	3.2	3.4	0.1	0.4	2.3	2.0	1.9	3.2	3.0	3.0	3.5	4.0	1.8	3.5	0.2	2.3	2.7	3.0	3.5	3.4
Pulse wave reflection index	1.3	1.6	6.2	1.1	0.8	0.8	1.1	-0.8	0.3	-2.3	-1.6	1.2	-2.5	1.4	0.8	0.9	0.4	1.0	2.1	0.5	2.4	1.3	0.1	1.6	0.0	0.5
Health satisfaction	1.3	1.6	6.1	-1.3	1.1	1.3	1.6	0.6	0.5	-1.1	-2.5	1.8	-1.1	1.0	1.3	1.2	0.5	0.3	1.9	0.8	1.8	2.0	0.6	1.7	0.5	0.8
Migraine (self-reported)	1.3	1.7	4.7	-0.5	-1.7	-1.4	-1.1	-2.2	-0.7	0.8	-0.7	-1.8	-0.3	-1.5	-1.4	-1.5	-1.5	-1.8	-0.9	-1.5	-0.3	-1.0	-0.9	-1.2	-1.6	-1.7
Smoking status: Previous	1.3	1.9	6.3	-0.5	1.7	1.4	1.3	0.5	1.9	-1.7	-0.9	1.3	-1.6	1.9	1.4	1.4	0.8	0.1	2.5	1.5	1.2	2.2	-1.0	0.9	0.9	1.0
Smoking status: Current	1.3	2.1	5.1	-0.2	-2.3	-1.3	-1.0	-2.0	-2.1	-1.8	-1.3	-0.2	-2.2	-1.5	-1.2	-1.2	-1.5	-1.5	-0.3	-1.8	1.3	-0.8	-0.2	-0.8	-2.0	-1.6
Deep venous thrombosis (DVT) (self-reported)	1.3	1.6	4.4	-0.3	2.1	1.4	1.2	1.8	1.8	0.8	0.5	0.8	1.0	1.5	1.4	1.2	1.5	1.4	1.2	1.8	-0.2	1.3	0.2	1.2	1.4	1.4
Breast Cancer	1.2	3.0	15.1	-3.9	0.1	-1.5	-1.4	-1.9	-2.6	-0.3	-1.8	-2.6	-1.2	-1.4	-1.4	-1.4	-1.9	-2.3	-0.7	-2.0	0.1	-0.2	-1.1	-1.8	-1.8	-1.7
Frequency of depressed mood in last 2 weeks	1.2	1.6	3.6	-0.2	-1.8	-1.5	-1.7	-1.3	-1.2	0.4	-0.7	-1.0	0.4	-1.6	-1.5	-1.5	-1.4	-1.0	-1.9	-1.9	-0.8	-1.2	-0.2	-1.4	-1.5	-1.5
Angina	1.2	1.6	10.2	1.4	0.0	-0.2	-0.3	1.9	3.2	2.0	1.3	-1.2	2.7	0.3	-0.3	-0.3	0.6	0.5	-0.9	0.7	-2.1	-0.8	-0.7	-0.6	0.6	0.2
Severe depression (siblings)	1.2	1.4	4.5	-1.2	-2.0	-1.1	-0.7	-1.8	-0.1	0.0	-1.1	-0.1	-0.9	-1.1	-1.1	-1.1	-1.9	-1.8	0.2	-0.9	-0.1	-0.6	-2.1	-0.5	-1.6	-1.4
Trunk fat percentage	1.2	4.9	15.4	-0.8	-3.9	-2.7	-2.5	-2.1	-1.9	0.1	-0.2	-2.5	0.4	-2.6	-2.7	-2.8	-2.5	-2.2	-2.1	-2.6	-1.1	-2.4	-1.3	-2.1	-2.7	-2.8
Average weekly fortified wine intake	1.2	1.4	3.3	-0.1	1.7	1.1	1.1	1.3	1.2	1.3	1.2	1.4	1.5	1.1	1.0	1.1	1.4	1.4	0.8	1.8	-0.3	0.7	0.4	1.4	1.4	1.4
Bilateral oophorectomy (both ovaries removed)	1.2	1.4	3.9	1.3	1.4	1.3	1.5	2.0	0.4	1.0	0.2	0.3	1.0	0.6	1.4	1.4	1.4	1.3	0.4	1.2	0.6	0.6	1.9	1.3	1.6	1.5
High blood pressure	1.2	3.5	8.9	0.1	-3.0	-2.3	-2.5	-1.6	-2.1	1.3	0.6	-2.0	1.1	-2.1	-2.3	-2.3	-1.7	-1.1	-2.1	-2.1	-1.5	-2.5	-0.8	-1.6	-2.0	-2.2
Body mass index (BMI)	1.2	5.2	13.1	0.8	-3.6	-2.9	-2.7	-1.6	-3.5	0.3	-0.5	-2.5	0.7	-2.1	-2.8	-2.8	-2.1	-1.7	-2.2	-2.6	-1.5	-2.7	-1.5	-2.8	-2.7	-2.8
Angina (self-reported)	1.2	1.5	10.7	1.0	0.3	-0.0	-0.1	2.0	3.3	1.9	1.4	-1.1	2.6	0.5	-0.1	-0.1	0.7	0.7	-0.7	0.9	-1.9	-0.6	-0.6	-0.3	0.8	0.4
Hypertension (Self-reported)	1.2	3.4	8.4	-0.0	-2.9	-2.3	-2.3	-1.6	-2.4	1.5	0.8	-2.0	1.2	-1.9	-2.3	-2.3	-1.6	-0.8	-2.1	-1.9	-1.7	-2.5	-0.8	-1.4	-2.0	-2.1
Mood swings	1.2	2.2	5.1	-0.9	-1.8	-1.6	-1.8	-1.4	-1.8	0.0	-0.6	-0.7	-0.0	-1.6	-1.6	-1.7	-1.9	-2.3	-1.4	-1.9	-0.9	-0.7	-1.4	-2.0	-1.9	-1.8
Illnesses of father: None of the above (group 1)	1.2	1.5	5.7	-1.2	-2.4	-1.4	-0.7	-2.0	-0.7	0.1	-1.3	-1.8	-1.0	-0.7	-1.3	-1.3	-1.5	-0.5	-0.1	-0.8	-0.7	-1.0	-1.8	0.0	-1.5	-1.4
Neuroticism (2016)	1.1	1.5	4.9	-2.1	-0.4	-1.3	-1.1	-1.5	-1.2	0.0	-0.8	-2.2	-0.4	-1.1	-1.2	-1.3	-1.6	-1.0	-0.9	-1.3	-0.7	-0.8	-1.2	-1.0	-1.9	-1.4
Blood Eosinophil Count	1.1	8.2	21.9	-2.4	4.7	3.4	3.5	3.0	4.1	-0.1	2.3	2.1	0.7	2.8	3.3	3.3	3.0	2.0	2.2	3.6	0.3	3.7	1.6	3.0	3.6	3.4
Hair Pigment	1.1	30.8	69.4	-4.8	-8.3	-6.6	-5.9	-7.6	-3.5	-0.5	0.4	-6.0	-2.1	-6.8	-6.5	-6.5	-7.2	-7.5	-4.0	-6.0	-2.8	-4.6	-5.4	-4.3	-6.6	-6.8
Current tobacco smoking	1.1	1.8	4.9	-0.5	-2.0	-1.2	-0.9	-2.0	-2.1	-1.8	-1.1	-0.5	-2.2	-1.4	-1.1	-1.1	-1.4	-1.3	-0.2	-1.6	1.2	-0.7	-0.3	-0.7	-1.8	-1.4
Number of incorrect matches in round	1.1	1.8	9.4	2.3	2.3	1.1	0.6	1.8	3.1	0.5	1.3	1.5	0.7	1.4	1.1	1.1	1.5	0.7	0.5	1.3	-0.3	0.8	0.2	-0.3	1.5	1.3
Noisy workplace	1.1	1.3	4.5	1.1	2.1	1.4	1.3	1.5	0.3	-0.1	0.1	0.9	0.7	1.6	1.3	1.3	1.7	1.3	0.9	1.1	0.6	1.1	0.9	0.3	1.4	1.4
Number of full sisters	1.1	1.4	3.8	-2.0	-0.9	-1.1	-0.2	-1.1	0.1	-0.7	-1.9	-1.9	-1.3	-0.9	-1.0	-1.0	-1.2	-1.7	0.0	-1.6	0.8	0.1	-0.7	-1.1	-1.7	-1.4
Osteoporosis (self-reported)	1.1	1.4	3.8	-1.0	1.1	1.4	1.7	0.8	1.0	-0.3	0.2	-0.4	-0.6	1.0	1.5	1.4	1.2	1.4	1.1	1.2	0.9	1.3	1.5	2.0	1.3	1.3
Myopia	1.1	1.7	4.5	-0.2	1.7	1.5	1.7	0.3	0.5	-1.5	0.4	1.4	-1.5	1.7	1.6	1.6	1.2	0.5	2.1	1.4	1.6	1.7	0.2	0.9	1.0	1.3
Basal cell carcinoma (self-reported)	1.1	1.4	12.9	0.2	-0.0	-0.7	-0.4	-0.3	0.4	3.6	0.5	-0.6	2.0	-0.6	-0.8	-0.7	-0.7	-0.6	-1.1	0.3	-2.5	-0.9	-1.8	-0.4	0.0	-0.3
Bipolar Disorder (2011)	1.0	1.0	4.0	-2.0	0.7	1.0	1.3	-0.5	-0.0	-1.3	-1.4	-0.2	-1.7	0.9	1.0	1.0	0.4	0.3	1.6	0.3	2.0	0.0	0.6	0.0	0.2	0.6
HDL Cholesterol	1.0	1.6	6.4	-0.1	-2.5	-1.4	-1.5	-1.4	-2.1	-0.4	-0.8	-0.9	-0.5	-1.3	-1.3	-1.4	-1.4	-1.0	-1.1	-1.6	-0.4	-1.4	-0.6	-1.2	-1.6	-1.5
Lung FEV1/FVC ratio	1.0	5.0	13.6	0.9	-3.7	-2.7	-2.9	-2.5	-1.4	-0.2	-0.5	-1.7	-0.1	-2.5	-2.6	-2.7	-2.5	-3.0	-1.7	-2.3	-1.3	-2.1	-2.5	-2.5	-2.7	-2.8
Pain all over the body in last month	1.0	1.1	5.5	-0.4	1.1	0.3	0.7	-0.4	0.2	-1.9	-1.7	0.9	-2.3	1.0	0.4	0.5	0.2	-0.4	1.6	-0.0	1.8	1.7	-0.3	-0.1	-0.4	0.0
Asthma	1.0	1.9	5.4	-0.1	-1.6	-1.4	-1.0	-0.6	-2.0	1.8	-0.1	-2.1	1.3	-1.8	-1.4	-1.4	-1.2	-0.8	-2.3	-1.5	-1.6	-1.6	0.1	-1.2	-1.0	-1.2
Suffer from ‘nerves’	1.0	1.6	6.6	-0.4	-1.1	-0.9	-0.8	0.4	-0.0	1.6	2.2	-1.9	2.1	-1.5	-1.0	-1.1	-0.5	-0.3	-2.6	-1.2	-1.8	-1.2	0.8	-1.4	-0.3	-0.7
Whole body fat-free mass	1.0	5.6	13.8	-0.8	3.7	2.7	2.8	3.0	0.0	0.3	2.0	1.4	1.8	2.9	2.6	2.6	3.1	3.3	1.7	3.1	0.1	2.1	2.0	2.5	3.0	2.9
Average weekly red wine intake	1.0	1.5	4.4	0.6	-1.2	-1.0	-0.9	-0.1	-0.8	2.1	1.3	-2.0	2.1	-1.3	-1.1	-1.0	-0.3	-0.2	-2.1	-0.8	-1.7	-1.7	0.3	-1.3	-0.2	-0.6
Medication: Gliclazide	1.0	1.1	1.9	-0.7	-1.2	-1.4	-0.2	-1.0	-1.1	0.9	0.5	-1.2	0.3	-1.1	-1.4	-1.3	-1.1	-1.3	-0.9	-1.1	-0.9	-1.1	-1.1	-1.3	-1.2	-1.3
Whole body water mass	1.0	5.6	13.9	-0.8	3.7	2.7	2.7	3.1	0.1	0.4	2.2	1.3	2.0	2.9	2.5	2.5	3.1	3.3	1.6	3.1	-0.2	2.0	1.9	2.4	3.1	2.9
Pain experienced in last month	1.0	1.8	5.9	-0.6	1.6	1.5	1.4	0.5	-0.1	-1.1	-0.1	1.1	-1.0	1.1	1.5	1.6	1.2	2.0	1.1	1.3	1.3	1.1	2.0	2.4	1.4	1.5
Alzheimer’s Disease (including proxy)	0.9	1.3	5.5	-0.1	-0.3	-1.3	-1.4	-0.9	1.8	0.1	0.6	-0.4	0.4	-0.7	-1.3	-1.2	-1.1	-2.1	-0.8	-0.5	-1.5	-0.7	-2.3	-2.0	-0.8	-1.0
Schizophrenia (2014)	0.9	2.0	6.1	-0.1	1.8	1.5	1.5	0.9	-0.5	-2.1	-2.1	1.3	-1.7	1.5	1.6	1.5	1.0	0.6	1.8	0.4	2.5	2.2	1.1	0.8	0.7	0.9
Hand grip strength (right)	0.9	2.3	15.9	-2.0	2.3	0.8	0.5	-0.8	-4.0	-0.8	-3.1	0.4	-2.4	1.3	0.9	0.9	0.3	-0.0	1.7	-0.1	2.1	1.5	0.2	-0.1	-0.1	0.4
Fluid intelligence score	0.9	1.8	6.6	-0.6	1.4	1.6	1.0	0.1	1.1	-1.1	-0.3	2.6	-1.1	1.0	1.5	1.5	0.8	1.2	1.8	1.3	1.5	1.6	1.0	2.6	1.1	1.2
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	2.3	0.2	1.5	1.1	1.1	0.1	1.3	-1.1	-1.3	0.6	-0.7	1.0	1.1	1.1	0.8	0.6	1.3	0.8	1.3	1.3	0.5	1.1	0.7	1.0
Age at first live birth	0.9	1.6	4.1	-0.7	1.8	1.5	1.6	-0.4	1.3	-2.0	0.1	0.7	-1.6	1.2	1.6	1.4	0.9	0.7	1.5	1.1	1.7	1.7	0.9	1.3	0.7	1.1
Overall health rating	0.9	2.0	5.1	0.2	-2.3	-1.7	-1.2	-0.7	-0.6	0.5	0.1	-0.8	0.9	-1.8	-1.7	-1.8	-1.6	-2.2	-1.5	-1.8	-1.1	-1.0	-1.3	-1.9	-1.8	-1.9
Long-standing illness, disability or infirmity	0.9	1.4	4.5	2.1	-1.3	-1.1	-1.1	0.3	0.0	1.9	1.1	-0.5	1.9	-1.4	-1.1	-1.2	-0.4	-0.1	-2.0	-0.8	-1.7	-1.7	0.3	-0.8	-0.4	-0.9
Back pain experienced in last month	0.9	1.2	3.4	1.9	-1.6	-1.1	-1.2	-0.3	-0.3	1.2	0.5	-0.1	1.2	-1.2	-1.1	-1.2	-0.9	-1.2	-1.1	-0.9	-1.3	-1.2	-1.3	-1.5	-1.0	-1.1
Asthma (self-reported)	0.9	1.9	5.1	-0.5	-1.6	-1.4	-0.9	-0.7	-2.3	1.8	-0.3	-2.2	1.3	-1.7	-1.4	-1.4	-1.3	-0.6	-2.1	-1.4	-1.5	-1.6	0.0	-0.9	-1.1	-1.2
Depression (Nagel 2018)	0.8	1.2	2.9	-1.5	-1.3	-1.2	-1.3	-0.7	-1.0	1.1	0.3	-1.5	1.0	-1.2	-1.2	-1.1	-1.0	-0.6	-1.7	-1.4	-1.1	-0.9	0.2	-0.7	-1.0	-1.0
Triglycerides	0.8	1.3	4.7	1.4	-0.4	-1.3	-1.5	-0.5	0.4	0.9	0.4	-1.2	1.4	-1.0	-1.4	-1.3	-0.9	-0.8	-1.4	-0.3	-2.2	-1.4	-1.5	-1.2	-0.6	-0.9
Smoking Status	0.8	1.8	9.5	-0.4	0.9	1.0	1.0	-0.5	0.1	-3.1	-1.1	2.0	-2.9	0.8	1.0	1.0	0.3	0.0	1.8	0.3	2.3	1.8	0.7	1.3	0.2	0.6
Respiratory disease	0.8	1.9	5.4	-1.1	-1.6	-1.6	-1.0	-0.9	-1.0	1.5	-0.4	-2.3	0.8	-1.6	-1.6	-1.5	-1.6	-1.5	-1.9	-1.5	-1.2	-1.2	-0.7	-1.4	-1.3	-1.4
Average weekly spirits intake	0.8	1.0	2.6	-0.2	-1.6	-1.2	-1.2	-1.6	-1.5	0.1	0.2	-0.4	-0.3	-1.1	-1.2	-1.2	-1.2	-1.3	-0.4	-0.8	-0.5	-0.8	-1.0	-0.5	-1.2	-1.3
Systolic blood pressure, automated reading	0.8	2.4	5.3	1.3	-2.1	-1.8	-2.3	-1.2	-1.4	-0.2	0.2	-1.9	0.1	-1.7	-1.7	-1.8	-1.1	-0.5	-2.0	-2.3	-0.1	-2.3	0.7	-1.8	-1.8	-1.8
Taking other prescription medications	0.8	1.3	4.9	-0.3	-1.3	-0.9	-0.5	-0.1	-0.4	2.1	1.7	-1.3	1.6	-1.4	-0.9	-1.0	-0.5	-0.0	-2.2	-0.7	-1.9	-1.3	0.7	-0.4	-0.2	-0.6
Tinnitus: Yes, but not now, but have in the past	0.8	0.9	2.5	0.5	-1.0	-0.9	-1.3	0.2	-0.9	1.2	0.8	-1.1	1.6	-0.7	-1.0	-0.9	-0.4	-0.3	-1.2	-0.6	-1.6	-1.5	-0.6	-1.0	-0.4	-0.6
Medication: Levothyroxine sodium	0.8	1.3	6.4	-1.0	-1.5	-0.6	-0.3	-1.5	-2.1	-0.3	-2.5	-0.7	-1.8	-1.1	-0.5	-0.6	-1.0	-0.7	-0.3	-1.5	1.4	-0.2	0.9	-0.1	-1.0	-0.9
Past tobacco smoking	0.8	1.4	6.7	0.2	-0.3	-0.7	-0.7	0.4	-1.1	2.6	1.4	-1.6	2.3	-1.0	-0.7	-0.7	-0.0	0.4	-2.1	-0.5	-1.6	-1.6	0.8	-0.8	0.0	-0.2
Neuroticism score	0.8	1.6	2.7	-1.5	-1.5	-1.4	-1.2	-0.7	-1.4	0.7	0.1	-1.1	0.5	-1.2	-1.4	-1.5	-1.5	-1.6	-1.4	-1.3	-1.5	-0.6	-1.4	-1.6	-1.4	-1.5
Loud music exposure frequency	0.8	0.8	4.0	1.4	1.8	0.7	0.4	1.6	-0.5	2.0	0.1	0.2	1.5	0.5	0.7	0.6	0.8	0.7	-0.5	0.3	-0.5	0.4	0.8	-0.2	0.9	0.7
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	3.6	1.1	1.9	1.2	1.3	1.7	0.4	0.6	-0.3	1.9	0.7	1.4	1.1	1.3	1.3	1.5	1.1	1.4	0.3	0.6	0.4	1.1	1.3	1.4
Arm predicted mass (right)	0.8	3.9	9.1	-0.4	3.0	2.1	2.3	2.8	0.3	0.3	2.3	0.8	1.8	2.4	2.0	2.1	2.6	2.7	1.3	2.6	-0.1	1.5	1.6	1.8	2.6	2.4
Illness, injury, bereavement, stress in last 2 years	0.8	1.0	2.0	-0.5	1.0	1.2	1.3	1.3	0.1	-0.0	1.3	0.6	0.4	1.1	1.2	1.1	1.3	1.3	1.0	1.4	0.2	0.8	0.9	1.3	1.2	1.1
Wears glasses or contact lenses	0.8	0.9	3.9	0.0	0.7	0.6	0.9	0.1	1.6	-0.6	-0.6	0.0	-0.8	1.5	0.7	0.7	0.5	0.5	2.0	1.4	0.2	1.1	-1.6	0.9	0.5	0.6
Commuting to job workplace: Public transport	0.8	1.0	3.8	-1.1	0.8	1.0	1.6	-0.2	0.1	-1.6	-0.6	0.1	-2.0	0.3	1.1	1.0	0.3	-0.3	1.2	0.7	1.6	1.5	0.6	1.2	0.5	0.7
Ever had prostate specific antigen (PSA) test	0.8	0.9	3.2	-0.6	0.9	0.8	1.1	1.3	1.0	1.0	1.8	0.1	1.6	0.4	0.8	0.8	1.2	0.8	-0.2	0.9	-0.6	0.3	1.0	0.6	1.3	1.1
Unable to work because of sickness or disability	0.8	1.1	5.0	1.8	-0.3	-0.3	-0.3	1.2	2.2	1.8	1.5	0.2	2.2	-0.2	-0.4	-0.3	0.5	0.4	-1.3	0.0	-1.5	-0.8	-0.0	-0.6	0.5	0.1
Vascular/heart problems diagnosed by doctor	0.8	2.1	6.0	-0.4	2.5	1.7	1.9	0.8	1.3	-1.5	-0.9	1.7	-1.3	1.5	1.7	1.8	1.1	0.4	1.8	1.3	1.6	2.1	0.4	0.9	1.3	1.6
Reaction Time	0.7	1.3	8.0	1.2	0.2	0.1	0.0	1.7	1.0	1.7	2.3	-0.8	2.8	0.2	-0.0	-0.1	0.6	0.1	-1.3	0.5	-2.3	0.0	-0.3	-1.0	0.9	0.4
Medication: Co-codamol	0.7	0.8	5.7	0.4	0.0	-0.1	0.2	1.5	1.4	1.3	2.4	-0.8	1.8	-0.2	-0.1	-0.1	0.6	0.2	-0.6	0.5	-1.3	-0.4	0.1	-0.1	0.7	0.2
Hayfever, allergic rhinitis or eczema	0.7	1.5	5.8	-0.4	1.7	1.1	0.8	1.8	0.2	2.4	1.6	-0.4	2.3	0.6	0.9	0.9	1.1	0.9	-0.2	1.4	-1.4	0.7	0.6	0.8	1.6	1.2
Mouth/teeth dental problems	0.7	1.1	4.6	-0.2	1.3	1.1	1.1	-0.5	-0.2	-1.8	-1.0	1.0	-1.7	0.5	1.1	1.1	0.7	0.2	0.9	0.2	2.1	1.2	1.5	0.6	0.4	0.8
Time employed in main current job	0.7	0.8	4.6	-2.1	-0.5	-0.7	-0.1	-0.5	1.4	0.1	1.0	-1.8	0.6	-0.2	-0.7	-0.8	-0.6	-0.6	-0.3	0.0	-1.5	0.0	-1.6	-0.4	-0.5	-0.7
Birth weight of first child	0.7	1.3	4.1	-0.5	1.3	1.2	1.2	1.4	-0.3	0.9	-1.4	1.2	0.5	1.2	1.1	1.1	1.0	1.6	1.3	1.4	0.9	1.2	1.0	2.0	1.0	1.0
Arm fat-free mass (right)	0.7	3.7	8.7	-0.4	3.0	2.1	2.2	2.7	0.3	0.4	2.1	0.7	1.8	2.3	2.0	2.0	2.6	2.7	1.2	2.5	-0.2	1.4	1.7	1.8	2.5	2.3
Mouth/teeth dental problems: Loose teeth	0.7	0.8	3.6	-1.7	-0.8	-0.8	-0.6	0.1	-1.9	1.0	0.2	-1.7	1.0	-0.2	-0.8	-0.7	-0.5	-0.0	-0.3	-0.2	-1.4	-0.5	-1.3	-0.3	-0.6	-0.6
Mean time to correctly identify matches	0.7	1.4	5.9	1.8	-0.7	-0.6	-0.7	0.8	1.3	1.6	2.4	-0.5	2.3	-0.5	-0.7	-0.7	-0.2	-0.4	-1.4	-0.1	-2.4	-0.8	-0.9	-1.0	0.2	-0.4
Leg fat mass (right)	0.7	2.8	6.1	-0.1	-2.5	-2.1	-1.8	-1.3	-2.2	0.1	0.1	-2.2	0.6	-1.6	-2.1	-2.1	-1.6	-1.5	-1.6	-1.9	-1.1	-1.8	-1.1	-2.2	-2.0	-2.1
Medication: Lisinopril	0.7	0.9	2.5	-1.2	1.1	0.9	0.9	0.5	0.8	-0.5	0.8	-0.9	-0.2	1.4	0.9	0.9	1.0	1.1	1.4	1.6	0.2	1.0	-0.2	1.3	0.9	0.9
Arm fat-free mass (left)	0.7	3.6	8.3	-0.5	2.8	2.0	2.2	2.6	-0.1	0.3	2.1	0.8	1.9	2.2	1.9	2.0	2.5	2.9	1.1	2.4	-0.2	1.3	1.8	1.9	2.4	2.3
Average weekly beer plus cider intake	0.7	1.0	3.1	-1.6	1.5	0.9	1.1	0.7	-0.3	-1.1	-0.9	0.7	-0.7	0.9	1.0	0.9	0.4	0.5	1.4	0.6	1.8	1.2	0.7	1.2	0.3	0.7
Fractured/broken bones in last 5 years	0.7	0.9	2.1	-1.1	1.4	1.1	1.3	0.9	0.6	0.5	0.0	-0.3	0.4	0.8	1.1	1.1	1.1	0.7	0.8	1.3	0.3	1.1	0.8	1.2	1.1	1.1
Supplements: Calcium	0.7	0.7	2.5	-1.6	0.7	1.0	1.4	0.8	1.0	0.6	1.0	-0.6	0.1	0.3	1.0	1.0	0.6	0.2	0.3	1.1	-0.5	0.8	0.4	1.0	1.3	1.1
Leg fat mass (left)	0.7	2.7	6.1	-0.0	-2.5	-2.0	-1.8	-1.2	-2.1	0.1	0.1	-2.2	0.6	-1.4	-2.0	-2.1	-1.5	-1.5	-1.5	-1.8	-1.1	-1.8	-1.3	-2.2	-2.0	-2.1
Intelligence (Savage-Jansen 2018)	0.6	1.7	4.5	-1.0	1.2	1.1	1.4	-0.5	1.7	-1.6	-1.3	1.7	-2.0	0.9	1.1	1.3	0.4	0.4	2.0	1.1	1.8	1.6	0.4	2.1	0.8	1.0
Number of treatments/medications taken	0.6	1.0	3.8	-0.7	-1.3	-0.9	-0.9	-0.1	-0.1	1.4	1.3	-1.8	1.4	-1.1	-0.9	-0.9	-0.5	-0.9	-1.4	-0.4	-1.9	-1.0	-0.6	-0.9	-0.2	-0.6
Vitamin and mineral supplements	0.6	0.8	4.3	1.5	0.8	0.5	0.4	0.8	-0.9	-0.1	1.6	0.1	0.9	0.7	0.5	0.5	1.1	2.1	-0.1	0.5	0.3	-0.3	1.7	0.8	0.7	0.7
Supplements: Zinc	0.6	0.6	3.0	0.7	-0.5	-0.7	-0.5	0.4	-1.2	1.7	0.3	-0.6	1.4	-0.4	-0.7	-0.7	-0.4	-0.0	-0.7	-0.2	-1.7	-0.9	-0.9	-0.5	-0.2	-0.5
Pack years adult smoking proportion	0.6	0.9	2.8	1.7	-1.5	-0.9	-1.4	-1.0	-1.5	-0.8	-0.5	0.2	-0.0	-0.8	-0.9	-0.9	-0.7	-0.3	-0.8	-1.3	0.1	-1.2	0.0	-1.1	-1.2	-1.0
Chronic bronchitis/emphysema (father)	0.6	0.7	4.0	1.5	0.4	0.3	0.3	-0.4	-0.4	-0.6	-0.8	1.6	-1.3	-0.1	0.3	0.4	0.4	0.6	0.0	-0.7	2.0	-0.1	2.0	0.2	0.1	0.2
Allergy	0.6	1.3	6.6	-0.1	-1.5	-0.9	-0.8	-1.9	-0.5	-2.6	-0.9	0.4	-2.2	-0.7	-0.8	-0.8	-1.1	-1.1	0.1	-1.4	1.4	-0.4	-0.3	-0.7	-1.4	-1.1
Medication: Simvastatin	0.6	0.9	2.4	0.6	-1.5	-1.1	-1.4	-1.3	0.1	0.0	0.8	-0.8	-0.5	-0.8	-1.1	-1.2	-0.9	-1.0	-0.7	-0.9	-0.5	-1.2	-1.2	-1.4	-1.1	-1.1
Headache pain in last month	0.6	1.0	3.4	-0.2	-1.1	-0.8	-0.6	-0.9	-0.6	1.5	-0.4	-1.8	0.8	-0.9	-0.8	-1.0	-1.0	-1.1	-1.1	-0.9	-1.2	-1.1	-1.1	-1.5	-0.8	-0.9
Shortness of breath walking on level ground	0.6	0.7	5.0	-0.5	-0.5	-0.1	0.1	-0.9	-0.9	-1.1	-2.2	0.0	-1.6	-0.4	0.0	-0.0	-0.4	-0.6	0.7	-0.6	1.7	0.4	0.5	0.2	-0.6	-0.3
Eye problems/disorders: None of the above	0.6	0.6	4.5	-0.3	0.0	0.0	0.4	-1.1	-0.6	-1.3	-2.1	-0.1	-1.5	0.2	0.1	0.1	-0.1	-0.9	0.9	-0.5	1.4	0.9	-0.1	-0.5	-0.6	-0.2
Heart disease (mother)	0.6	0.8	3.8	1.9	-0.5	-0.4	-0.8	0.6	1.8	0.8	0.7	-0.1	1.3	-0.7	-0.4	-0.5	0.1	-1.1	-0.8	-0.2	-0.9	-0.9	-0.5	-1.4	-0.0	-0.3
Whole body fat mass	0.6	2.5	6.9	-0.7	-2.6	-1.9	-1.7	-1.3	-2.1	0.0	0.2	-2.0	0.7	-1.6	-1.9	-2.0	-1.6	-1.3	-1.5	-1.7	-1.0	-1.7	-1.0	-1.6	-1.9	-2.0
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	5.4	2.3	0.3	-0.2	0.1	1.0	1.0	1.4	0.7	0.2	1.8	0.4	-0.3	-0.3	0.6	0.2	-0.4	0.5	-1.0	-0.7	-0.6	-1.1	0.3	0.0
Illnesses of father: Heart disease	0.6	0.8	6.0	1.6	0.5	0.3	-0.3	1.6	0.3	0.5	2.5	0.1	2.1	0.1	0.2	0.1	0.8	0.4	-0.5	0.6	-1.0	-0.2	0.4	-0.2	0.8	0.5
Leg fat-free mass (right)	0.6	3.0	6.4	-1.1	2.4	1.9	1.9	2.2	-0.3	0.3	1.7	0.6	1.8	2.2	1.8	1.7	2.2	2.5	1.4	2.5	-0.4	1.4	1.0	1.9	2.1	2.0
Ever had bowel cancer screening	0.6	0.7	5.4	-1.5	0.1	0.1	0.6	0.7	1.6	1.0	2.3	-0.7	1.4	-0.3	0.0	-0.1	-0.0	-0.8	0.0	0.5	-1.0	0.4	-0.9	0.0	0.3	0.0
Commuting to job workplace: Walk	0.6	0.7	1.1	-0.8	0.9	1.0	0.6	0.1	0.2	-1.0	-0.3	0.8	-1.1	0.8	1.0	0.9	0.8	1.0	0.9	0.6	1.1	0.8	0.9	1.0	0.7	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	4.2	0.9	2.0	1.3	1.2	1.1	1.1	-1.3	-1.3	1.4	-1.3	1.1	1.3	1.3	1.1	0.2	1.2	0.8	1.4	1.4	0.6	0.5	1.1	1.2
Leg predicted mass (right)	0.6	3.0	6.5	-1.1	2.5	1.9	1.9	2.2	-0.4	0.3	1.7	0.6	1.7	2.3	1.8	1.8	2.2	2.5	1.4	2.5	-0.3	1.5	1.0	1.9	2.2	2.0
Arm fat mass (left)	0.6	2.5	6.2	-0.2	-2.5	-2.0	-1.8	-1.0	-2.5	0.3	-0.3	-1.8	0.8	-1.6	-2.0	-2.0	-1.5	-1.2	-1.7	-1.8	-1.0	-1.9	-0.7	-1.8	-1.9	-2.0
Medication: Atorvastatin	0.6	0.8	2.3	-0.7	-1.2	-0.9	-0.8	-0.6	-0.5	0.3	-0.1	-1.5	0.3	-0.6	-0.9	-0.9	-0.9	-1.2	-0.9	-0.6	-1.4	-0.4	-1.4	-1.3	-0.7	-0.8
Basal metabolic rate	0.6	3.5	8.4	-0.8	2.9	2.0	2.1	2.5	-0.4	0.4	1.9	0.9	1.9	2.3	1.9	1.9	2.5	2.8	1.1	2.5	-0.2	1.5	1.7	1.8	2.4	2.2
Diastolic blood pressure, automated reading	0.6	1.8	7.1	1.5	-1.8	-1.3	-2.2	-1.0	-2.7	0.0	-0.1	-1.7	0.4	-1.2	-1.2	-1.4	-0.8	0.2	-1.5	-1.6	-0.2	-1.9	0.7	-1.1	-1.5	-1.3
Alcohol drinker status: Previous	0.6	0.7	3.5	-0.9	-0.2	-0.2	-0.3	1.2	-0.2	1.1	1.1	-1.9	1.7	-0.8	-0.2	-0.2	-0.2	-0.7	-1.2	-0.2	-1.1	-0.0	0.2	-0.5	0.3	-0.0
Pack years of smoking	0.6	0.9	2.7	1.6	-1.6	-0.9	-1.3	-1.1	-1.2	-0.9	-0.4	0.4	-0.1	-0.7	-0.9	-0.9	-0.6	-0.3	-0.6	-1.2	0.1	-1.2	-0.2	-1.0	-1.2	-1.0
Arm predicted mass (left)	0.6	3.3	8.0	0.0	2.6	1.8	1.9	2.7	-0.2	0.6	2.3	0.7	2.2	2.0	1.7	1.7	2.4	2.8	0.7	2.2	-0.5	1.0	1.8	1.6	2.4	2.1
Coronary Artery Disease (CAD)	0.5	0.6	2.2	1.5	1.1	0.1	0.6	1.2	1.2	0.1	0.1	1.4	0.6	0.6	0.1	0.5	0.4	-0.1	0.6	0.8	-0.4	0.1	-1.1	-0.0	0.7	0.8
Fasting Glucose	0.5	0.6	2.7	0.4	-0.8	-0.6	-0.7	0.4	-0.6	1.3	0.7	-0.3	1.6	-0.6	-0.6	-0.6	-0.1	0.0	-1.4	-0.3	-1.4	-1.3	0.5	-0.9	-0.1	-0.3
Blood White Count	0.5	4.0	30.2	-5.5	2.2	1.7	1.7	1.7	2.4	-0.3	2.8	-1.3	1.8	1.3	1.7	1.7	1.5	0.9	1.0	2.5	-1.5	2.0	0.1	1.9	2.2	1.9
Sensitivity / hurt feelings	0.5	0.9	11.5	-3.4	-0.5	-0.0	0.2	-0.8	0.1	-0.9	-0.7	-0.9	-0.8	-0.5	0.0	0.0	-1.2	-1.3	0.3	-0.3	0.2	0.8	-0.9	0.5	-0.5	-0.3
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	2.2	0.1	1.5	0.7	0.8	0.2	-0.1	-1.0	-0.2	0.3	-0.8	1.3	0.7	0.8	0.4	1.1	1.1	0.8	0.6	0.8	0.0	1.1	0.5	0.7
Leg fat-free mass (left)	0.5	2.7	5.7	-1.2	2.4	1.7	1.8	2.1	-0.4	0.5	1.7	0.4	1.9	2.0	1.6	1.6	2.1	2.2	1.1	2.3	-0.5	1.4	1.0	1.5	2.0	1.9
Townsend deprivation index at recruitment	0.5	0.7	2.8	0.3	-1.2	-0.8	-0.4	-0.2	0.4	1.2	0.1	-0.5	1.2	-0.8	-0.8	-0.9	-0.5	-0.8	-0.9	-0.4	-1.7	-0.8	-1.2	-0.9	-0.4	-0.7
Stomach or abdominal pain in last month	0.5	0.6	3.2	1.8	-1.0	-0.8	-0.4	-0.1	-0.2	0.6	-0.2	-0.6	0.2	-0.7	-0.8	-0.9	-0.5	-0.7	-0.8	-1.1	-0.4	-0.8	-0.4	-1.3	-0.8	-0.9
Leg predicted mass (left)	0.5	2.8	5.9	-1.1	2.4	1.8	1.8	2.2	-0.3	0.5	1.8	0.6	1.9	2.1	1.7	1.7	2.2	2.4	1.1	2.4	-0.5	1.4	1.2	1.6	2.1	1.9
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.2	5.2	2.3	-1.7	-0.8	-1.0	-0.1	-1.4	0.6	-1.5	0.7	0.3	-1.5	-0.8	-0.9	-0.5	-0.6	-1.4	-1.5	0.3	-1.2	1.1	-1.0	-0.7	-0.9
Medication: Ramipril	0.5	0.6	4.1	1.4	0.8	0.6	0.1	0.6	2.0	-0.2	0.8	1.3	0.1	0.5	0.6	0.5	0.8	0.7	0.3	0.5	0.4	0.2	0.9	0.5	0.6	0.5
Arm fat mass (right)	0.5	2.1	6.3	-0.1	-2.2	-1.8	-1.6	-0.8	-2.5	0.5	-0.1	-1.6	1.0	-1.4	-1.9	-1.9	-1.3	-1.0	-1.6	-1.6	-1.1	-1.7	-0.6	-1.6	-1.6	-1.8
Peak expiratory flow (PEF)	0.5	1.3	4.7	0.7	1.0	1.0	0.8	0.4	-1.1	-1.6	-1.8	1.9	-1.5	0.8	1.0	1.0	0.6	0.5	1.4	0.4	2.2	1.1	1.0	1.0	0.4	0.7
High blood pressure (siblings)	0.5	0.7	2.1	0.1	1.2	0.7	0.6	0.5	1.4	-0.9	-0.6	0.9	-0.4	1.1	0.8	0.7	0.7	0.2	1.4	0.8	0.8	1.3	-0.4	0.6	0.4	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.5	0.1	1.6	1.0	1.0	0.5	0.9	-0.8	0.3	0.7	-0.7	1.1	1.0	1.1	1.1	0.3	0.9	0.5	0.8	1.1	0.4	-0.1	0.9	1.0
Wheeze or whistling in the chest in last year	0.5	0.9	5.4	1.4	0.8	0.1	0.2	1.6	0.1	2.2	0.4	-0.1	2.3	0.3	0.1	-0.1	0.9	0.8	-0.6	0.5	-1.4	-0.6	0.0	-0.4	0.6	0.3
Medication: Ibuprofen	0.5	0.6	2.2	-1.5	0.6	0.8	0.7	0.9	-0.2	-1.4	-0.2	-0.1	-0.2	0.6	0.8	0.9	0.3	-0.3	1.1	0.9	0.2	1.1	-0.4	0.6	0.7	0.7
Pulse rate, automated reading	0.5	1.6	5.1	-1.2	-2.2	-1.1	-1.4	-1.7	-2.1	-1.2	-0.4	-1.4	-1.0	-1.1	-1.0	-1.1	-1.5	-1.6	-0.1	-1.0	-0.3	-0.6	-1.4	-0.8	-1.5	-1.3
Had major operations	0.5	0.6	5.2	-2.3	-1.0	-0.4	-0.3	-0.4	-1.9	-0.3	-0.7	-1.1	-0.2	-0.8	-0.3	-0.3	-0.5	-0.7	-0.4	-0.7	0.5	-0.1	0.5	-0.2	-0.5	-0.4
Age at last live birth	0.5	0.7	4.1	-0.1	0.3	0.2	0.4	-1.4	0.5	-1.7	-1.1	0.2	-2.0	0.2	0.2	0.1	-0.5	-1.0	0.7	-0.3	1.1	0.8	-0.7	-0.6	-0.7	-0.2
Knee pain experienced in last month	0.5	0.8	4.5	2.0	0.7	0.3	0.0	1.3	2.1	0.6	1.4	-0.3	1.6	0.7	0.3	0.3	1.0	0.0	0.2	0.7	-0.6	-0.3	-0.7	-1.0	0.6	0.5
Mineral and other dietary supplements	0.5	0.7	3.4	1.8	0.9	0.9	0.2	0.5	-0.3	0.5	-0.5	1.4	0.5	0.9	0.8	0.8	0.8	1.4	0.6	0.8	0.7	0.2	0.8	0.9	0.6	0.8
Osteoarthritis (self-reported)	0.5	0.6	3.6	1.9	-0.9	-0.4	-0.5	0.7	0.5	0.5	1.3	-0.2	1.6	-0.8	-0.4	-0.4	0.1	0.5	-1.0	-0.0	-0.9	-1.3	0.6	0.1	0.1	-0.1
Pain type(s) experienced in last month: Hip pain	0.5	0.6	2.6	0.8	0.7	0.3	0.3	1.0	1.0	1.3	1.3	-0.6	1.6	0.4	0.2	0.1	0.6	-0.2	-0.3	0.7	-1.4	-0.0	-0.7	-0.8	0.7	0.4
Ever smoked	0.5	0.9	4.7	-0.3	-0.6	0.0	0.1	-0.9	0.8	-2.2	-1.5	1.1	-2.1	0.1	0.1	0.1	-0.6	-0.8	1.5	-0.2	1.4	0.8	-0.8	0.5	-0.6	-0.3
Bipolar Disorder or Schizophrenia	0.4	1.1	4.8	0.0	0.6	0.9	1.2	0.2	-1.4	-1.8	-1.4	0.7	-1.6	0.8	1.0	0.9	0.5	0.4	1.2	-0.1	2.2	1.4	1.2	0.5	0.1	0.4
Schizophrenia (2018)	0.4	0.7	3.5	0.6	0.7	0.7	0.8	-0.0	-1.0	-1.5	-1.4	0.6	-1.3	0.6	0.8	0.7	0.5	0.1	0.7	-0.3	1.9	1.0	1.1	-0.2	0.1	0.3
Worry (Nagel 2018)	0.4	0.8	4.4	-2.1	0.7	0.4	0.6	1.1	0.6	1.2	1.9	-1.0	1.4	0.1	0.4	0.3	0.4	0.6	-0.7	0.3	-0.9	0.7	1.0	0.5	0.6	0.5
Body Mass Index (BMI) (2010)	0.4	0.5	2.0	-0.3	-0.2	0.4	0.5	-0.6	-1.1	-1.4	-1.3	0.9	-1.4	0.2	0.4	0.4	0.1	0.3	0.7	-0.2	1.4	0.4	0.7	0.7	-0.1	0.1
Crohns Disease (2012)	0.4	0.7	2.5	-1.6	1.5	0.9	0.3	0.2	0.8	-0.7	-0.8	0.2	-0.2	0.8	0.9	0.8	0.8	0.1	1.2	0.3	1.4	1.4	0.7	0.5	0.4	0.6
Systolic Blood Pressure	0.4	2.2	11.0	3.3	-1.5	-1.4	-1.9	-1.0	-1.3	-0.4	0.2	-0.1	-0.6	-1.4	-1.3	-1.4	-0.5	0.1	-1.8	-2.4	0.8	-2.0	1.8	-1.5	-1.5	-1.5
Chronotype (morning person)	0.4	0.8	3.4	1.3	-0.0	-0.3	-0.1	1.1	-0.8	1.1	1.4	-1.9	1.6	0.1	-0.3	-0.2	0.8	1.2	-1.0	-0.3	-0.9	-1.2	1.0	-0.6	0.3	0.1
Medication for hormone replacement therapy	0.4	0.4	1.5	1.0	1.2	0.5	0.3	0.6	0.4	-0.1	-0.3	1.1	-0.3	0.9	0.5	0.5	0.3	-0.2	0.9	0.9	0.1	0.6	-1.0	-0.1	0.4	0.5
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	4.4	2.1	-1.2	-0.6	-0.8	0.2	-1.6	0.4	-0.6	0.2	0.4	-1.3	-0.6	-0.8	-0.2	-0.2	-1.6	-1.3	0.2	-1.1	1.4	-1.1	-0.5	-0.7
Trunk fat mass	0.4	1.6	5.1	-1.0	-2.2	-1.5	-1.3	-1.1	-1.6	-0.0	0.3	-1.7	0.6	-1.3	-1.6	-1.6	-1.3	-1.0	-1.1	-1.3	-0.8	-1.3	-0.7	-1.1	-1.5	-1.6
Had other major operations	0.4	0.5	2.1	0.6	-0.8	-0.6	-0.6	0.1	0.5	0.9	0.7	-1.0	1.0	-0.2	-0.5	-0.6	-0.2	-0.5	-0.3	0.2	-1.4	-0.3	-1.4	-0.6	-0.3	-0.5
Diabetes (self-reported)	0.4	0.6	2.1	-0.2	-0.6	-0.8	-1.0	-1.1	-0.8	-0.5	-0.9	-0.6	-0.6	-0.2	-0.8	-0.8	-0.7	-1.0	-0.2	-1.1	0.2	-0.4	-0.8	-1.5	-1.1	-1.0
Hip circumference	0.4	1.6	8.4	0.0	-2.2	-1.4	-1.3	-0.9	-2.9	0.1	-0.2	-1.1	0.9	-1.1	-1.5	-1.5	-1.1	-0.2	-1.2	-1.2	-0.9	-1.7	-0.4	-0.8	-1.4	-1.4
Father’s age at death	0.4	0.5	2.1	-0.3	-0.7	-0.1	-0.6	-0.4	0.1	0.8	1.1	-0.8	1.4	-0.5	-0.1	-0.2	0.1	1.3	-0.9	-0.2	-0.2	-0.9	1.4	0.7	0.0	-0.1
Happiness	0.4	0.5	4.1	-0.5	-0.6	-0.2	-0.2	-0.3	-1.3	0.5	-2.0	0.9	0.1	-0.8	-0.2	-0.3	-1.1	-1.1	-0.5	-0.5	0.0	0.2	-0.3	-0.1	-0.6	-0.4
Medication: Cholesterol lowering	0.4	0.6	2.0	-0.3	-1.1	-0.6	-0.8	-1.2	0.2	-1.1	0.2	-1.4	-1.2	-0.5	-0.6	-0.7	-0.7	-0.8	-0.3	-0.8	0.2	-0.3	-0.4	-0.8	-0.9	-0.8
Length of working week for main job	0.4	0.5	1.3	-0.7	-0.8	-0.8	-0.6	-0.9	-1.2	-0.2	-0.1	-0.6	-0.1	-0.9	-0.8	-0.7	-0.8	-0.6	-0.9	-0.8	-0.5	-0.8	-0.1	-0.5	-0.7	-0.7
Tense / ‘highly strung’	0.4	0.6	1.8	0.8	-1.1	-0.9	-0.6	0.1	0.1	1.3	-0.1	-0.3	0.8	-0.9	-0.9	-1.0	-0.6	-0.9	-1.1	-0.8	-1.1	-0.5	-0.5	-1.0	-0.7	-0.9
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.5	-0.3	-1.2	-0.9	-0.3	-0.9	-0.0	0.7	0.6	-0.2	0.0	-0.9	-0.9	-0.9	-0.6	-0.5	-0.6	-0.4	-0.8	-1.1	-0.7	-0.3	-0.7	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	1.9	-0.3	1.2	0.7	0.5	1.4	0.2	-0.1	-0.7	0.8	-0.0	0.5	0.6	0.7	0.6	1.0	0.2	0.4	0.5	0.8	1.0	0.9	0.7	0.7
Emphysema/chronic bronchitis	0.4	0.4	3.5	0.1	-0.2	-0.1	0.0	-0.5	1.0	-0.8	-1.9	-0.0	-1.2	-0.0	-0.0	-0.1	-0.2	-0.5	0.4	-0.3	1.1	0.1	-0.2	-0.5	-0.5	-0.3
Chest pain or discomfort	0.4	0.5	2.5	1.6	-0.5	-0.4	-0.2	0.8	1.0	1.0	0.1	-0.2	1.3	-0.3	-0.5	-0.5	-0.2	0.8	-1.2	-0.5	-0.6	-0.9	0.7	-0.2	-0.2	-0.3
Illnesses of siblings: Diabetes	0.4	0.5	1.7	0.2	-1.0	-0.3	-0.2	-0.9	-0.5	-0.8	-1.3	-0.2	-1.3	-0.4	-0.3	-0.4	-0.5	-1.1	0.3	-0.8	0.9	-0.1	-0.4	-0.7	-0.7	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.4	0.7	3.7	0.4	0.3	0.2	-0.2	1.0	0.5	1.1	1.4	0.1	1.6	0.8	0.1	0.1	0.3	0.5	0.4	1.2	-1.9	0.0	-1.5	0.3	0.6	0.3
Breast cancer (self-reported)	0.4	0.5	1.9	0.8	0.2	0.8	0.7	1.0	1.4	-0.1	0.1	0.9	0.1	0.1	0.8	0.7	0.6	0.6	0.3	0.7	0.2	0.2	0.8	1.0	0.8	0.8
Medication: Aspirin	0.4	0.5	2.8	1.7	-0.9	-0.7	-0.7	-0.0	0.4	0.6	0.3	-0.0	0.4	0.3	-0.7	-0.7	-0.2	0.4	-0.0	0.1	-1.0	-0.9	-1.4	-0.3	-0.4	-0.6
Mother’s age at death	0.4	0.6	3.4	0.7	-0.5	-0.1	-0.4	0.3	1.0	1.6	1.3	-0.0	1.8	-0.5	-0.2	-0.2	-0.1	0.1	-1.3	0.0	-1.2	-0.4	0.3	-0.3	0.4	0.1
Tinnitus: Yes, now most or all of the time	0.4	0.5	2.2	1.5	-1.3	-0.6	-0.2	-0.0	-0.1	1.1	0.1	0.1	0.5	-0.5	-0.6	-0.6	-0.6	-0.4	0.0	0.2	-0.9	-0.7	-1.4	0.5	-0.3	-0.5
Eye problems/disorders: Glaucoma	0.4	0.5	1.9	0.6	-0.7	-0.6	-1.1	-0.4	-0.2	0.9	0.9	0.3	1.0	-1.0	-0.6	-0.7	0.1	0.4	-1.2	-0.7	-0.6	-1.4	1.0	-0.2	-0.3	-0.5
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.6	-0.7	-0.8	-0.8	-0.2	-0.7	0.2	-0.6	-0.1	-0.9	-0.7	-0.3	-0.8	-0.8	-0.4	-1.1	-0.2	-0.7	-0.2	-0.2	-1.0	-1.3	-0.8	-0.8
Heart disease (siblings)	0.4	0.5	1.8	1.2	0.3	-0.3	-0.7	0.7	1.0	0.8	0.0	0.1	1.1	0.3	-0.4	-0.4	0.0	-0.5	-0.4	0.2	-1.1	-0.0	-1.3	-1.2	-0.1	-0.2
Bipolar Disorder (2018)	0.3	0.4	1.3	-0.7	0.1	0.6	0.9	0.3	-1.0	-1.0	-0.5	0.5	-0.9	0.5	0.6	0.5	0.2	0.5	1.0	0.2	1.2	0.9	0.5	1.0	0.1	0.2
Depressed Affect (Nagel 2018)	0.3	0.5	2.3	-0.8	-1.0	-0.6	-0.7	-0.4	-1.0	0.0	0.5	-0.5	0.4	-1.0	-0.6	-0.7	-0.6	-0.5	-1.5	-1.2	-0.5	-0.5	0.7	-0.7	-0.6	-0.6
Ulcerative Colitis (UC)	0.3	0.5	3.1	-1.8	0.0	-0.7	-0.6	-0.8	-0.2	0.2	-0.6	-0.2	-0.5	-0.6	-0.7	-0.7	-1.1	-1.0	0.2	-0.7	-0.1	-0.0	-1.2	0.1	-1.0	-0.9
HbA1C	0.3	0.3	1.4	0.8	-0.1	-0.4	-0.4	-0.2	-0.2	0.5	-1.2	0.1	-0.4	-0.2	-0.4	-0.4	-0.6	-1.2	-0.2	-0.6	0.2	-0.1	-0.8	-1.0	-0.7	-0.6
Type 2 Diabetes (T2D) (2012)	0.3	0.4	3.3	0.2	1.8	0.6	0.2	0.9	0.4	-0.0	-0.7	0.6	0.1	0.7	0.5	0.6	0.7	-0.1	0.7	0.2	0.6	0.8	-0.0	-0.5	0.5	0.5
Waist Hip Ratio (WHR)	0.3	1.5	4.2	0.5	1.8	1.4	1.3	1.1	2.1	-0.2	1.6	1.4	-0.1	1.2	1.4	1.3	1.3	0.9	1.1	1.5	0.4	1.5	0.6	1.3	1.4	1.3
Allergy or Eczema	0.3	0.9	5.8	-0.3	1.1	0.2	0.1	0.9	1.2	2.4	1.0	-1.0	2.0	0.0	0.1	0.1	0.3	-0.1	-0.6	0.7	-1.8	0.3	-0.5	-0.1	0.8	0.4
Type 2 Diabetes (T2D) (2018)	0.3	0.6	2.6	1.4	-1.0	-0.9	-0.8	-0.5	-0.6	0.3	-0.5	-0.2	0.0	-0.6	-0.9	-0.8	-0.6	-1.1	-0.7	-1.0	-0.5	-0.7	-0.8	-1.6	-0.8	-0.8
Relative age of first facial hair	0.3	0.6	3.5	0.5	0.3	0.1	0.1	1.2	-0.1	1.2	1.3	-0.6	1.9	0.1	0.1	0.2	0.6	0.7	-1.0	0.2	-1.0	-0.4	0.8	-0.6	0.6	0.5
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.8	-1.1	-0.4	-0.3	0.1	-0.7	0.2	-0.8	-1.3	0.6	-1.1	-0.3	-0.2	-0.2	-0.8	-0.9	0.7	-0.3	0.6	0.2	-0.8	0.4	-0.6	-0.5
Maternal smoking around birth	0.3	0.4	2.0	-0.5	0.7	0.2	0.7	0.4	1.1	0.3	1.0	-0.3	0.2	0.9	0.2	0.2	0.5	-0.3	0.7	1.0	-0.9	0.7	-1.4	-0.4	0.5	0.3
Hayfever/allergic rhinitis (self-reported)	0.3	0.5	1.7	-1.3	-0.4	-0.6	-0.8	-0.5	-1.3	0.0	0.3	-1.1	-0.1	-0.8	-0.6	-0.6	-0.6	-1.0	-0.3	-0.7	-0.0	-0.4	-0.4	-0.6	-0.6	-0.7
Illnesses of siblings	0.3	0.5	2.0	0.7	-0.8	-0.6	-0.5	-0.5	-1.4	1.0	0.5	-0.3	0.2	-0.9	-0.7	-0.6	-0.6	0.1	-1.2	-0.6	-0.5	-1.2	0.5	-0.4	-0.3	-0.5
Number of live births	0.3	0.5	2.0	-1.4	0.2	0.4	0.4	0.6	0.3	-0.9	-1.2	0.4	-0.6	0.7	0.4	0.5	-0.1	-0.4	1.3	0.4	0.7	1.1	-1.0	0.4	0.1	0.3
Mouth/teeth dental problems: Dentures	0.3	0.5	2.6	0.0	-1.1	-0.7	-0.5	0.6	-0.1	1.6	1.0	-0.9	0.9	-0.5	-0.7	-0.7	-0.2	0.1	-0.6	-0.2	-1.1	-1.1	-0.5	-0.2	-0.2	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.6	-0.8	0.3	0.5	0.5	1.3	0.3	-0.8	0.1	-0.3	0.7	0.4	0.4	0.5	0.2	-0.4	0.5	0.8	-0.5	0.6	-0.7	0.2	0.7	0.6
Pulse wave Arterial Stiffness index	0.3	0.3	1.4	0.5	-0.3	0.3	0.6	-0.1	-0.4	-0.7	0.2	0.0	-0.4	0.8	0.3	0.3	0.4	1.2	0.9	0.7	0.3	0.2	-0.2	1.2	0.2	0.3
Exposure to tobacco smoke at home	0.3	0.3	2.5	1.1	0.2	-0.0	0.3	0.2	1.6	-0.1	0.7	0.5	0.4	0.5	-0.1	-0.0	0.6	0.9	0.4	0.5	0.0	-0.2	-0.1	0.4	0.2	0.1
Medication: Amlodipine	0.3	0.5	1.1	0.4	-0.9	-0.9	-1.0	-1.0	-0.6	-0.1	-0.8	-0.4	-0.6	-0.6	-0.9	-0.8	-0.8	-0.6	-0.5	-1.0	0.1	-0.4	-0.3	-0.5	-1.0	-0.9
Exposure to tobacco smoke outside home	0.3	0.3	2.2	-0.1	0.2	-0.2	-0.5	0.7	-0.6	0.8	0.2	-0.1	1.1	0.3	-0.3	-0.3	-0.0	-0.7	0.2	0.2	-0.9	0.1	-1.5	-1.0	-0.2	-0.3
Comparative body size at age 10	0.3	0.8	3.5	-1.5	0.3	0.2	-0.1	-0.9	-1.9	-1.7	-1.7	0.4	-1.7	0.6	0.2	0.1	-0.3	0.0	1.0	-0.2	1.1	0.8	-0.4	0.2	-0.6	-0.2
Number of children fathered	0.3	0.3	1.0	0.5	-0.4	-0.8	-0.6	-0.5	-0.5	0.2	-0.7	0.1	-0.4	-0.1	-0.8	-0.7	-0.3	-0.7	0.3	-0.7	0.4	-0.4	-1.0	-1.0	-0.8	-0.8
Medication for pain relief, constipation, heartburn	0.3	0.5	2.9	-1.3	0.9	0.1	0.3	-1.7	-0.3	-0.2	-0.4	0.6	-1.6	-0.1	0.1	0.0	-0.5	-0.2	0.2	-0.4	0.9	0.7	0.4	0.3	-0.6	-0.2
Medication: Blood pressure	0.3	0.4	2.6	-1.0	-0.8	-0.6	-0.6	-0.5	-0.2	0.3	1.3	-1.6	0.6	-0.6	-0.5	-0.6	-0.3	-0.3	-0.8	-0.4	-0.6	-0.4	0.1	-0.5	-0.5	-0.5
Medication: Seretide 50 evohaler	0.3	0.4	3.2	-0.7	-0.2	-0.0	-0.4	0.3	-1.8	0.2	0.1	0.3	0.4	-0.6	0.0	-0.0	0.4	0.5	-0.8	-0.3	-0.0	-0.3	1.7	0.3	0.2	0.1
Family relationship satisfaction	0.3	0.3	1.0	0.1	0.7	0.7	0.5	1.0	-0.1	0.4	-0.6	0.8	0.6	0.3	0.7	0.7	0.4	0.2	-0.1	0.4	0.2	0.5	0.8	-0.0	0.7	0.7
Medication: Aspirin	0.3	0.4	2.1	1.4	-1.0	-0.6	-0.5	-0.0	0.8	0.4	0.4	0.1	0.4	0.3	-0.6	-0.6	-0.3	0.6	0.0	0.3	-1.0	-0.9	-1.4	0.1	-0.3	-0.4
Supplements: Vitamin C	0.3	0.4	2.1	-0.2	0.0	-0.1	-0.2	-0.3	0.1	-0.7	-1.2	-0.7	-0.9	-0.1	-0.0	-0.1	-0.5	-1.4	0.2	-0.5	0.2	0.6	-1.0	-1.1	-0.4	-0.4
Diabetes diagnosed by doctor	0.3	0.5	2.4	-0.2	-0.5	-0.8	-0.7	-0.7	-0.5	-0.0	-0.2	-0.4	-0.1	-0.3	-0.8	-0.7	-0.6	-1.0	-0.4	-1.0	-0.2	-0.6	-0.8	-1.5	-0.9	-0.9
Guilty feelings	0.3	0.5	2.1	-1.0	0.9	0.6	0.9	0.4	0.1	-0.5	-0.9	0.5	-0.9	1.0	0.6	0.6	0.2	0.2	1.3	0.4	0.9	1.4	-0.1	0.7	0.1	0.3
Ever taken oral contraceptive pill	0.3	0.3	1.7	-1.3	0.3	0.5	0.3	-0.6	-0.2	-0.7	0.4	0.1	-0.8	-0.1	0.4	0.4	0.1	0.3	0.1	-0.1	0.8	0.6	1.1	0.7	0.3	0.3
Number of operations (self-reported)	0.3	0.4	1.2	-0.0	0.3	0.8	0.6	0.9	1.1	0.1	0.1	0.4	0.3	0.6	0.9	0.8	0.8	0.6	0.8	1.0	0.3	0.7	0.2	0.7	0.7	0.8
Irritability	0.3	0.4	1.2	0.1	-0.9	-0.7	-0.8	-0.7	-0.5	0.1	-0.3	0.1	-0.4	-0.8	-0.7	-0.8	-1.1	-1.1	-0.7	-0.7	-0.5	-0.1	-0.8	-0.6	-0.9	-0.8
Risk taking	0.3	0.4	3.5	1.2	-0.3	-0.0	0.5	0.1	-1.2	-0.2	-1.9	1.2	-0.7	-0.2	-0.1	-0.0	-0.1	0.3	0.3	-0.1	0.7	-0.3	0.4	0.5	-0.3	-0.1
Schizophrenia vs Biploar Disorder	0.2	0.3	3.1	0.6	0.8	0.2	-0.1	0.4	-0.2	1.0	-0.4	1.8	0.3	0.4	0.1	0.2	0.2	0.4	-0.0	0.2	-0.5	0.1	-0.2	-0.0	0.5	0.3
Mean Putamen Volume	0.2	0.3	0.9	0.4	-0.1	0.3	0.5	0.4	0.1	0.4	1.0	-0.3	1.0	0.3	0.3	0.3	0.6	0.9	-0.0	0.5	-0.4	-0.1	0.6	0.6	0.6	0.5
Ulcerative Colitis	0.2	0.2	2.4	-1.6	0.0	0.1	0.2	-0.2	0.1	-0.1	-0.6	0.2	-0.6	0.0	0.1	0.2	-0.2	-0.1	0.6	-0.3	0.9	0.6	0.3	0.8	-0.2	-0.0
Heel T-Score	0.2	1.6	12.0	3.5	-0.5	-0.7	-0.5	0.6	-1.6	1.5	-1.4	0.2	1.0	-1.0	-0.7	-0.8	0.4	0.2	-2.0	-1.3	-0.4	-1.6	1.6	-1.7	-0.2	-0.5
Medication: Metformin	0.2	0.2	1.1	-1.1	0.6	0.3	0.7	0.1	0.6	-0.4	-0.4	-0.3	-0.1	0.7	0.3	0.4	0.4	-0.1	0.9	0.3	0.4	0.6	-0.4	-0.1	0.2	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.2	-1.1	-0.3	-0.3	-0.6	0.2	-0.4	0.5	0.1	-0.1	0.6	-0.5	-0.3	-0.3	-0.3	-0.0	-0.8	-0.7	-0.4	-0.3	0.4	-0.2	-0.3	-0.2
Relative age voice broke	0.2	0.3	1.6	-0.0	0.3	-0.1	0.2	0.3	-0.2	0.3	1.2	-0.8	1.2	-0.1	-0.1	0.0	0.3	0.4	-0.9	0.1	-0.6	-0.5	0.6	-0.4	0.3	0.3
Serious illness, injury or assault to yourself	0.2	0.2	1.4	-0.0	0.7	0.6	0.3	0.7	-0.5	0.1	0.4	-0.2	0.3	0.2	0.6	0.5	0.6	0.6	-0.5	0.0	0.2	0.1	1.2	-0.2	0.6	0.5
Multivitamins +/- minerals	0.2	0.2	1.1	-0.5	-0.1	-0.1	0.1	-0.2	0.5	0.5	-1.1	0.6	-0.5	-0.1	-0.2	-0.1	-0.3	-0.9	0.3	-0.0	-0.3	0.2	-1.0	-0.3	-0.1	-0.2
Nervous feelings	0.2	0.4	3.3	-0.3	-0.3	-0.1	-0.1	0.5	-0.3	1.8	0.9	-0.7	1.3	-0.4	-0.1	-0.2	-0.0	0.3	-1.1	-0.2	-0.9	-0.3	0.7	-0.2	0.2	-0.1
Hearing difficulty/problems with background noise	0.2	0.3	1.7	1.3	0.5	0.3	0.0	1.1	0.6	0.1	0.8	-0.0	0.8	0.5	0.3	0.2	0.7	0.4	-0.0	0.3	-0.1	0.1	0.1	-0.3	0.4	0.3
Falls in the last year	0.2	0.3	2.2	-1.1	-0.0	0.0	0.3	0.6	-0.3	0.8	0.6	-0.7	1.5	-0.2	-0.0	-0.1	0.2	-0.1	-0.9	-0.2	-0.7	0.1	0.5	-0.7	0.2	0.0
Pulse rate	0.2	0.4	1.2	-0.4	-0.8	-0.3	-0.7	-0.3	-1.0	-0.4	-1.1	-0.8	-0.4	-0.6	-0.2	-0.4	-0.6	-1.1	-0.5	-0.6	-0.2	-0.3	-0.3	-1.0	-0.5	-0.4
Prospective memory result	0.2	0.2	1.2	0.5	-0.9	-0.4	0.0	-0.1	-0.6	-0.3	-1.1	-0.5	-0.5	-0.2	-0.4	-0.4	-0.6	0.2	0.1	-0.4	0.1	-0.2	-0.1	0.5	-0.5	-0.5
Lung cancer (father)	0.2	0.3	1.0	1.0	-1.0	-0.2	-0.6	-0.8	0.3	-0.3	-0.3	0.5	-0.9	-0.2	-0.2	-0.2	-0.4	0.2	0.4	-0.2	0.4	-0.4	-0.2	0.8	-0.4	-0.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.2	0.3	0.1	-0.3	-0.2	-0.3	-1.0	-0.5	-1.0	-0.7	-0.6	-0.1	-0.2	-0.3	-0.2	-0.7	-0.3	-0.8	0.6	0.1	-0.0	-1.1	-0.5	-0.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.0	0.5	-0.7	-0.3	-0.3	-0.6	-0.9	0.4	-1.0	0.4	0.3	-0.6	-0.4	-0.3	-0.4	0.5	-0.3	-0.1	-0.1	-0.8	0.5	1.0	-0.3	-0.2
Glaucoma (self-reported)	0.2	0.2	1.1	0.7	-0.1	-0.0	-0.3	-0.0	-0.5	0.5	1.1	0.7	0.5	-0.1	-0.0	-0.1	0.6	0.7	-0.4	0.1	-0.3	-0.7	0.9	0.0	0.2	0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.2	-0.1	0.5	0.2	0.1	0.3	0.4	0.8	0.6	-0.8	1.1	0.5	0.2	0.2	0.4	0.6	-0.1	0.7	-1.1	-0.2	-0.4	0.1	0.6	0.4
Number of full brothers	0.2	0.2	0.6	-0.3	-0.5	-0.6	-0.4	0.1	-0.7	-0.0	-0.7	-0.5	0.2	-0.1	-0.7	-0.7	-0.4	-0.4	-0.2	-0.5	-0.5	-0.4	-0.8	-0.7	-0.6	-0.7
Pulse wave peak to peak time	0.2	0.2	0.8	-0.8	0.9	0.1	-0.2	0.4	0.7	0.7	-0.1	0.3	0.5	-0.5	0.1	0.1	-0.1	-0.8	-0.7	-0.3	-0.2	0.2	0.5	-0.7	0.2	0.1
Medication: Omeprazole	0.2	0.2	1.6	1.3	-0.8	-0.4	-0.5	0.0	0.4	-0.2	0.6	0.1	0.3	-0.5	-0.4	-0.4	-0.1	0.0	-0.6	-0.3	-0.2	-0.7	0.3	-0.2	-0.1	-0.2
Commuting to job workplace: Car/motor vehicle	0.2	0.2	1.1	0.2	0.7	0.2	0.3	0.1	-0.1	1.0	-0.1	0.3	1.0	0.4	0.2	0.2	0.3	0.5	-0.4	0.3	-0.6	0.1	0.2	-0.2	0.4	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	1.6	1.1	-0.3	-0.4	-0.5	0.6	0.2	0.4	0.4	-1.3	0.9	-0.1	-0.3	-0.3	0.2	-0.3	-0.6	-0.3	-0.4	-0.1	0.1	-0.9	0.0	-0.1
Friendships satisfaction	0.2	0.3	2.2	1.0	0.2	0.4	-0.1	-0.2	0.2	-0.2	-1.1	1.5	-0.4	0.2	0.3	0.3	-0.2	-0.2	0.7	0.3	0.6	0.5	-0.4	0.4	0.0	0.2
Miserableness	0.2	0.3	0.7	-0.7	-0.8	-0.4	-0.6	-0.3	-0.8	-0.2	0.3	0.1	0.6	-0.5	-0.5	-0.5	-0.3	-0.6	-0.4	-0.3	-0.8	-0.4	-0.6	-0.6	-0.5	-0.5
Medication: Paracetamol	0.2	0.3	1.1	-1.1	0.2	0.6	0.4	0.9	0.1	0.6	-0.6	-0.6	0.9	0.2	0.6	0.6	0.7	-0.3	0.2	0.4	-0.3	0.5	0.2	-0.2	0.7	0.6
Illnesses of father: High blood pressure	0.2	0.3	1.3	0.1	-0.3	-0.3	-0.4	0.0	0.1	-0.1	-0.7	0.1	0.1	-0.9	-0.3	-0.4	-0.4	-1.1	-0.8	-0.9	0.0	-0.2	0.4	-1.0	-0.4	-0.5
Neuroticism (Nagel 2018)	0.1	0.3	4.6	-2.1	-0.3	-0.2	-0.1	-0.2	-0.0	0.1	0.7	-0.9	0.2	-0.4	-0.1	-0.3	-0.4	-0.4	-0.7	-0.4	-0.6	0.5	0.2	-0.2	-0.2	-0.3
Irritable Bowel Disease (IBD)	0.1	0.3	2.7	-1.6	-0.1	-0.6	-0.6	-0.6	0.0	0.5	-0.1	-0.5	0.1	-0.7	-0.6	-0.5	-0.8	-0.9	0.1	-0.7	0.1	-0.1	-0.5	0.1	-0.7	-0.7
Ovarian Cancer	0.1	0.2	1.6	-0.1	0.7	-0.0	-0.1	0.0	-0.4	-0.1	-0.7	0.1	0.2	-0.4	-0.0	0.0	0.3	0.2	-0.5	-0.4	0.5	-0.3	1.3	-0.1	-0.0	0.1
BMI	0.1	0.7	4.5	0.7	-1.6	-1.0	-0.7	-0.3	-2.1	-0.5	-0.7	-1.3	-0.0	-0.3	-0.9	-0.9	-0.3	-0.1	-0.3	-0.9	-0.1	-0.8	-0.2	-0.8	-1.0	-0.9
Neuroticism	0.1	0.3	1.5	-1.2	-0.6	-0.5	-0.3	0.1	-0.6	0.4	0.8	-0.6	0.5	-0.4	-0.5	-0.5	-0.6	-0.5	-0.9	-0.5	-0.9	0.2	-0.3	-0.4	-0.5	-0.5
Diabetes (father)	0.1	0.2	1.8	0.5	0.5	-0.0	-0.7	0.4	-0.1	1.3	0.1	0.4	0.6	0.1	-0.1	-0.1	0.1	0.2	-0.2	-0.1	-0.1	-0.2	0.2	-0.3	0.1	-0.1
Impedance of leg (right)	0.1	0.4	1.7	0.0	-0.3	-0.3	-0.1	-0.9	1.2	0.2	-0.1	0.1	-0.7	-1.3	-0.4	-0.4	-0.9	-1.0	-1.1	-1.1	0.4	-0.4	0.7	-0.4	-0.5	-0.5
Age when periods started (menarche)	0.1	0.2	2.0	1.4	-0.7	-0.0	0.3	-0.1	1.2	0.1	0.3	0.1	-0.5	-0.5	0.0	-0.1	-0.0	-0.1	0.0	0.0	0.2	-0.3	0.4	0.7	0.1	-0.1
Supplements: Glucosamine	0.1	0.1	0.8	-0.2	-0.8	-0.1	0.5	0.3	0.6	-0.5	0.9	-0.1	0.0	-0.3	-0.1	-0.1	-0.4	-0.3	0.0	0.1	-0.5	0.2	-0.5	0.5	0.0	-0.1
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	0.8	-0.0	-0.1	-0.4	-0.2	0.1	-0.4	0.6	0.5	-0.9	0.9	-0.5	-0.4	-0.4	-0.0	-0.1	-0.5	-0.3	-0.2	-0.6	0.2	-0.3	-0.3	-0.3
Impedance of leg (left)	0.1	0.5	1.5	0.3	-0.6	-0.4	-0.4	-1.1	1.1	-0.1	-0.3	0.1	-0.8	-1.2	-0.5	-0.5	-1.0	-1.0	-0.8	-1.1	0.6	-0.5	0.3	-0.3	-0.7	-0.6
Waist circumference	0.1	0.5	2.2	-0.1	-1.3	-0.8	-0.7	-0.4	-1.5	-0.3	0.9	-1.0	0.6	-0.6	-0.9	-0.9	-0.5	-0.1	-0.6	-0.6	-0.6	-0.8	-0.2	-0.4	-0.8	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	0.7	0.3	-0.4	-0.3	0.1	0.1	-0.4	0.2	-0.8	0.5	0.3	-0.3	-0.3	-0.2	-0.2	0.3	-0.8	-0.6	0.1	-0.4	0.8	-0.2	-0.4	-0.2
Heart attack	0.1	0.1	1.0	1.0	-0.7	-0.3	-0.4	0.6	0.6	-0.3	-0.2	-0.2	-0.2	-0.0	-0.2	-0.2	-0.2	0.0	-0.0	0.1	-0.2	-0.2	-0.5	0.0	-0.1	-0.2
Weight	0.1	0.4	2.7	-0.6	-0.0	-0.0	0.1	0.5	-1.6	0.3	1.1	-0.6	1.3	0.3	-0.1	-0.1	0.4	0.8	-0.3	0.3	-0.8	-0.3	0.3	0.0	0.2	0.1
Impedance of arm (right)	0.1	0.3	2.2	-1.1	0.2	0.4	0.4	-0.6	1.5	0.2	-0.5	1.0	-0.5	-0.7	0.4	0.3	-0.4	-0.4	-0.1	0.0	0.3	0.6	0.5	0.9	0.2	0.2
Worrier / anxious feelings	0.1	0.2	1.8	-1.3	-0.3	0.0	-0.3	0.5	-0.8	0.6	0.5	-0.1	0.6	-0.4	0.0	-0.1	-0.3	-0.2	-0.2	-0.1	-0.4	0.2	0.1	0.3	-0.1	-0.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.2	1.6	-0.3	0.3	0.3	0.6	0.2	0.3	-0.4	-1.3	0.8	-0.1	-0.0	0.3	0.2	0.1	-0.3	-0.1	-0.2	0.4	0.7	0.5	-0.2	-0.1	0.2
Impedance of arm (left)	0.1	0.5	3.5	-1.3	-0.3	0.2	0.2	-1.0	1.9	0.1	-0.6	0.8	-0.8	-0.9	0.1	0.1	-0.7	-0.8	-0.1	-0.2	0.5	0.4	0.3	0.7	-0.2	-0.1
Medication: Paracetamol	0.1	0.2	1.4	-0.1	-0.1	0.4	0.4	1.1	0.2	0.4	-0.4	-0.3	1.2	0.1	0.4	0.4	0.6	-0.2	0.2	0.4	-0.5	0.3	-0.1	-0.1	0.6	0.5
Leg pain on walking	0.1	0.1	0.7	0.2	-0.5	-0.4	0.2	-0.1	0.8	-0.4	-0.5	-0.3	0.2	-0.2	-0.4	-0.4	-0.3	-0.3	-0.2	-0.4	-0.2	-0.2	-0.4	-0.5	-0.5	-0.5
Eye problems/disorders: Cataract	0.1	0.1	0.9	0.0	-0.4	-0.3	-0.4	0.3	-0.1	0.1	1.0	-0.0	-0.4	-0.3	-0.3	-0.3	-0.4	-0.6	-0.3	-0.0	-0.5	-0.3	-0.7	-0.3	-0.1	-0.3
Alcohol drinker status: Never	0.1	0.1	0.5	0.4	-0.4	-0.0	0.3	0.1	-0.5	-0.6	-0.2	0.1	-0.6	0.1	0.1	0.0	0.2	0.4	0.1	-0.3	0.7	-0.0	0.7	0.2	-0.1	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	2.1	1.4	-0.3	-0.1	-0.2	0.6	0.6	-0.6	0.4	0.2	-0.0	0.2	-0.1	0.0	0.2	0.3	-0.0	0.2	0.1	-0.2	0.1	-0.1	0.2	0.1
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.9	1.0	-0.7	-0.2	-0.4	0.4	0.6	-0.6	-0.4	-0.0	-0.5	-0.0	-0.2	-0.2	-0.3	-0.1	0.1	0.0	0.1	-0.1	-0.6	-0.1	-0.2	-0.2
Impedance of whole body	0.1	0.4	3.6	-0.6	-0.3	0.1	0.1	-0.9	1.9	0.1	-0.5	0.6	-0.7	-0.9	0.0	0.0	-0.7	-0.6	-0.3	-0.4	0.6	0.1	0.4	0.6	-0.2	-0.1
Crohns Disease (2017)	0.0	0.1	0.4	-0.6	0.3	-0.0	-0.2	0.0	0.6	0.1	0.2	-0.3	0.4	-0.2	-0.0	0.0	0.0	-0.5	0.2	-0.3	0.4	0.2	0.2	-0.0	-0.0	-0.1
Tanning	0.0	0.3	2.4	0.2	0.1	-0.2	0.0	1.0	0.0	1.6	0.5	0.6	1.2	-0.1	-0.2	-0.1	0.3	-0.2	-0.4	0.2	-1.2	-0.3	-0.4	-0.5	0.4	0.2

Hub : Genes

FAM136A

Models

Trait associations