[Hub]/) : Traits : Sitting height : ← →

chr4:105,373,669-107,092,169

Best TWAS P=5.15e-35 · Best GWAS P=1e-42 conditioned to 2.36e-06

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PPA2	0.08	0.03	bslmm	429	0.04	2.2e-05	-8.6	-9.5	3.2e-21	0.61	0.04	0.94	FALSE
2	GTEx	Adipose Subcutaneous	PPA2	0.15	0.02	enet	36	0.06	7.0e-06	6.0	-5.3	9.2e-08	0.36	0.26	0.12	FALSE
3	GTEx	Artery Aorta	PPA2	0.11	-0.01	enet	24	0.01	1.6e-01	-13.1	-8.9	8.2e-19	0.61	0.05	0.53	FALSE
4	GTEx	Brain Cerebellum	PPA2	0.22	0.01	lasso	4	0.03	3.7e-02	-9.2	-7.8	5.3e-15	0.57	0.08	0.25	FALSE
5	GTEx	Brain Cortex	PPA2	0.14	0.09	lasso	9	0.09	1.6e-03	-10.9	-10.9	9.3e-28	0.83	0.06	0.53	FALSE
6	GTEx	Cells Transformed fibroblasts	PPA2	0.11	0.03	lasso	3	0.01	6.5e-02	-8.4	-9.6	6.0e-22	0.61	0.37	0.21	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	PPA2	0.29	0.15	lasso	5	0.14	8.8e-06	-13.1	-12.3	5.1e-35	0.84	0.04	0.94	TRUE
8	GTEx	Esophagus Mucosa	PPA2	0.18	0.06	enet	14	0.12	2.5e-08	11.7	-12.2	2.2e-34	0.71	0.02	0.98	TRUE
9	GTEx	Heart Atrial Appendage	PPA2	0.15	0.05	lasso	7	0.06	7.4e-04	-10.5	-6.8	8.9e-12	0.67	0.21	0.44	FALSE
10	GTEx	Muscle Skeletal	PPA2	0.19	0.06	enet	28	0.11	8.7e-11	-10.3	-6.5	9.6e-11	0.60	0.62	0.38	FALSE
11	GTEx	Nerve Tibial	PPA2	0.13	0.07	enet	23	0.07	2.1e-05	-9.2	-8.9	7.5e-19	0.66	0.49	0.26	TRUE
12	GTEx	Ovary	PPA2	0.18	0.10	lasso	3	0.14	2.2e-04	-9.2	-11.1	1.9e-28	0.73	0.06	0.69	FALSE
13	GTEx	Skin Sun Exposed Lower leg	PPA2	0.09	0.07	lasso	3	0.04	4.3e-04	6.4	-6.4	1.4e-10	0.38	0.66	0.04	FALSE
14	GTEx	Skin Sun Exposed Lower leg	TET2	0.09	0.01	enet	18	0.02	3.6e-03	-13.3	-10.3	4.2e-25	0.62	0.02	0.88	FALSE
15	GTEx	Thyroid	PPA2	0.22	0.01	enet	18	0.12	2.9e-09	7.7	-7.5	4.4e-14	0.50	0.68	0.15	FALSE
16	METSIM	Adipose	PPA2	0.08	0.05	lasso	2	0.04	3.7e-07	6.4	6.5	6.4e-11	-0.33	0.96	0.00	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	PPA2	0.32	0.38	lasso	2	0.38	1.1e-51	6.4	-7.1	1.0e-12	0.48	1.00	0.00	FALSE
18	YFS	Blood	PPA2	0.22	0.05	lasso	19	0.12	9.7e-38	-4.3	7.7	1.7e-14	-0.48	1.00	0.00	FALSE
19	The Cancer Genome Atlas	Thyroid Carcinoma	PPA2	0.04	0.02	blup	84	0.04	6.1e-05	-10.3	-9.1	8.6e-20	0.73	0.14	0.65	FALSE