Best TWAS P=3.63e-10 · Best GWAS P=2.19e-16 conditioned to 1.12e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | TRMT10A | 0.35 | 0.26 | lasso | 9 | 0.26 | 4.8e-12 | 5.2 | 6.3 | 3.6e-10 | 0.75 | 0.96 | 0.04 | TRUE |
| 2 | METSIM | Adipose | TRMT10A | 0.05 | 0.00 | bslmm | 512 | 0.01 | 2.1e-02 | 7.4 | 6.0 | 2.2e-09 | 0.57 | 0.03 | 0.81 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | MTTP | 0.02 | 0.01 | blup | 75 | 0.01 | 7.2e-03 | 3.8 | -5.5 | 4.0e-08 | -0.28 | 0.17 | 0.02 | FALSE |