[Hub]/) : Traits : Sitting height : ← →

chr5:36,410,564-40,159,666

Best TWAS P=1.98e-27 · Best GWAS P=1.33e-30 conditioned to 2.79e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C5orf42 0.04 0.03 lasso 4 0.04 1.2e-05 -6.21 7.0 2.4e-12 -0.65 0.46 0.40 FALSE
2 GTEx Cells Transformed fibroblasts WDR70 0.06 0.03 lasso 8 0.03 3.5e-03 -8.86 9.1 1.3e-19 -0.72 0.41 0.38 FALSE
3 GTEx Nerve Tibial WDR70 0.17 0.07 lasso 3 0.05 1.4e-04 7.60 7.1 9.6e-13 -0.43 0.40 0.03 FALSE
4 GTEx Whole Blood NUP155 0.05 0.01 enet 14 0.04 1.1e-04 -11.50 6.8 9.8e-12 -0.61 0.01 0.87 FALSE
5 GTEx Whole Blood C5orf42 0.07 0.00 enet 16 0.01 1.8e-02 -11.50 5.8 5.6e-09 -0.68 0.02 0.79 FALSE
6 METSIM Adipose OSMR 0.03 0.00 blup 479 0.01 1.1e-02 2.66 -5.9 3.8e-09 -0.06 0.29 0.06 TRUE
7 YFS Blood DAB2 0.20 0.20 lasso 14 0.21 3.0e-67 7.13 -7.2 4.0e-13 0.05 1.00 0.00 TRUE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DAB2 0.04 0.01 enet 9 0.02 3.3e-03 -8.91 -7.1 1.7e-12 0.00 0.02 0.71 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma C9 0.04 0.00 blup 89 0.03 2.8e-04 -3.83 -6.1 9.7e-10 0.04 0.02 0.06 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C5orf42 0.04 0.05 lasso 3 0.04 1.1e-03 -11.00 10.9 2.0e-27 -0.92 0.00 0.94 TRUE
11 The Cancer Genome Atlas Prostate Adenocarcinoma DAB2 0.07 0.00 enet 6 0.02 2.1e-03 1.97 -6.0 1.6e-09 -0.03 0.01 0.67 TRUE
12 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma DAB2 0.18 -0.01 blup 83 0.05 2.0e-02 0.53 -6.4 1.3e-10 0.05 0.02 0.13 FALSE