[Hub]/) : Traits : Sitting height :

chr5:133,164,490-134,784,086

Best TWAS P=1.46e-10 · Best GWAS P=6.19e-18 conditioned to 6.04e-12

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SAR1B 0.12 0.06 lasso 6 0.09 8.1e-11 -4.5 -5.3 1.4e-07 0.22 0.99 0.00 FALSE
2 GTEx Cells EBV-transformed lymphocytes PHF15 0.26 0.18 lasso 6 0.22 7.1e-08 5.6 5.9 3.1e-09 -0.21 0.71 0.03 FALSE
3 GTEx Colon Transverse SAR1B 0.11 0.00 enet 17 0.03 1.2e-02 -4.2 -6.2 6.8e-10 0.16 0.07 0.04 TRUE
4 GTEx Muscle Skeletal SAR1B 0.10 0.04 lasso 7 0.04 6.1e-05 4.3 -6.0 2.7e-09 0.22 0.23 0.14 FALSE
5 GTEx Pituitary CAMLG 0.20 0.07 enet 10 0.09 3.3e-03 -4.6 -5.2 2.6e-07 0.25 0.50 0.03 FALSE
6 The Cancer Genome Atlas Glioblastoma Multiforme CAMLG 0.29 0.18 lasso 3 0.13 9.6e-05 -4.7 -5.2 2.2e-07 0.29 0.00 0.84 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SAR1B 0.03 0.00 blup 27 0.01 2.6e-02 5.6 -6.4 1.5e-10 0.27 0.00 0.85 TRUE