[Hub]/) : Traits : Sitting height :

chr5:176,040,488-177,426,530

Best TWAS P=3.12e-15 · Best GWAS P=8.32e-12 conditioned to 0.025

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous MXD3 0.16 0.05 enet 13 0.06 1.7e-05 3.4 6.1 8.7e-10 -0.15 0.89 0.02 FALSE
2 GTEx Artery Aorta LMAN2 0.13 0.10 lasso 6 0.06 1.9e-04 -5.4 -5.5 3.0e-08 0.26 0.51 0.10 FALSE
3 GTEx Artery Aorta MXD3 0.36 0.22 enet 45 0.29 2.4e-16 3.4 5.2 2.4e-07 -0.27 1.00 0.00 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia MXD3 0.24 0.14 enet 10 0.25 2.9e-07 3.4 5.3 1.1e-07 -0.06 0.27 0.06 FALSE
5 GTEx Breast Mammary Tissue MXD3 0.26 0.08 lasso 5 0.10 1.3e-05 3.4 6.1 1.0e-09 -0.20 0.20 0.63 FALSE
6 GTEx Breast Mammary Tissue (Female) MXD3 0.23 0.08 lasso 3 0.09 1.1e-03 5.3 6.3 2.7e-10 -0.17 0.05 0.38 FALSE
7 GTEx Nerve Tibial MXD3 0.26 0.17 lasso 7 0.28 6.9e-20 3.4 5.3 1.3e-07 -0.04 1.00 0.00 FALSE
8 GTEx Skin Sun Exposed Lower leg MXD3 0.19 0.14 lasso 6 0.12 4.2e-10 5.3 5.8 5.5e-09 -0.10 0.94 0.06 FALSE
9 GTEx Stomach RGS14 0.11 0.17 enet 6 0.17 1.1e-08 -4.7 5.2 2.2e-07 -0.08 0.92 0.01 FALSE
10 GTEx Thyroid MXD3 0.31 0.17 lasso 8 0.24 1.1e-18 3.4 5.7 1.2e-08 -0.11 0.97 0.03 FALSE
11 YFS Blood MXD3 0.04 0.03 lasso 4 0.04 5.8e-13 -5.2 7.9 3.1e-15 -0.65 0.28 0.72 TRUE
12 The Cancer Genome Atlas Colon Adenocarcinoma RAB24 0.08 0.04 enet 7 0.06 3.4e-04 -5.4 6.2 5.3e-10 -0.26 0.01 0.70 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma LMAN2 0.04 0.00 blup 46 0.00 1.6e-01 5.3 -7.3 3.1e-13 0.53 0.01 0.41 FALSE
14 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RGS14 0.05 0.03 enet 5 0.05 7.2e-06 -4.1 5.2 1.8e-07 -0.06 0.20 0.70 FALSE
15 The Cancer Genome Atlas Brain Lower Grade Glioma RGS14 0.03 0.02 blup 39 0.03 8.1e-05 -3.0 5.6 1.8e-08 -0.17 0.03 0.96 FALSE